Obstetric Labor, Premature clinical trials
The registry lists 242 studies for Obstetric Labor, Premature across more than 10 countries. 36 are recruiting or about to start. 135 of them are mainly about Obstetric Labor, Premature (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Premature Birth too: 2,692 studies, 516 open.
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Who runs them
Assiut University (14) · Ain Shams University (7) · Ain Shams Maternity Hospital (6) · GlaxoSmithKline (5) · Stanford University (5) · University of California, San Francisco (4) · Indiana University (4) · University of Pennsylvania (4)
What is being tested here
Drugs under test in Obstetric Labor, Premature studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Azithromycin | 3 | 1 | 3 |
| Amoxicillin | 2 | 0 | 2 |
| Caffeine citrate | 2 | 0 | 2 |
| Caffeine | 2 | 0 | 2 |
| Progesterone | 1 | 2 | 21 |
| Indomethacin | 1 | 2 | 10 |
| Aspirin | 1 | 0 | 1 |
| Erythromycin | 1 | 0 | 1 |
| Metformin | 1 | 1 | 1 |
| Vitamin D | 1 | 0 | 1 |
Drug classes tested here NSAIDs 2 open · Progestins 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Sleep Improvement Therapy Affects Pregnancy Outcomes in Chinese Singletons and Twins by Improving Sleep Quality · Jun Wei
- Dec 2026Urinary Infection in Pregnant Women with Urinary Infection · Assiut University
- Dec 2026Single Dose of Antenatal Corticosteroids for Pregnancies at Risk of Preterm Delivery (SNACS) · McMaster University
- Jan 2027Short-Term Tocolysis in Preterm Labor · Sohag University
- Jan 2027Low Dose Antenatal Corticosteroids for Late Preterm Delivery · Rambam Health Care Campus
- Feb 2027Low Dose Aspirin vs Placebo in Prevention of Recurrent Spontaneous Preterm Labour · University of Health Sciences Lahore
- Feb 2027FB-CT2 Includes Two Prospective, Multi-centre Studies With a Medical Device in Hospital Settings: a Randomized, Dual-arm, Open-label Pilot Study in Spain, Followed by a Single-arm, Non-randomized, Open-label International Pivotal Study · Ultrasound-Innovation Medtech, S.L.
- Apr 2027The Combined Effect of Magnesium, Palmitoylethanolamide, High-Molecular-weight Hyaluronic Acid, Vitamin B6, and Vitamin D in Preventing Preterm Birth: · University of Roma La Sapienza
- Apr 2027Is the Vaginal Microbiome and Metabolome Associated With Spontaneous Preterm Birth (sPTB) in Multiple Pregnancies? · University of Liverpool
- Jun 2027Pharmacokinetics and Placental Transfer of Caffeine · Indiana University
Who these studies take
Of the 24 Obstetric Labor, Premature studies recruiting now, 14 (58%) set no upper age limit and 9 (38%) stop at 75 or younger. 5 (21%) take children under 18. 20 (83%) are for women only and 0 (0%) for men only; 8 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (8%) | 0 (0%) |
| 18 | 20 (83%) | 2 (8%) |
| 30 | 22 (92%) | 2 (8%) |
| 40 | 22 (92%) | 2 (8%) |
| 50 | 19 (79%) | 1 (4%) |
| 65 | 16 (67%) | 1 (4%) |
| 75 | 16 (67%) | 1 (4%) |
| 85 | 14 (58%) | 1 (4%) |
Across all 242 studies, recruiting or not: 60% stop at 75 or younger and 59% at 65; 28% take children; 90% are for women only and 0% for men only; 43% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Obstetric Labor, Premature studies take
Of 45 interventional studies with no phase under Obstetric Labor, Premature, half reached primary completion within 27 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 27 mo12–49 · 45 studies | — | 27 mo12–47 · 44 studies |
| Observational | 29 mo14–48 · 39 studies | — | 30 mo19–48 · 33 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
- Cervical Stiffness in Women With Threatened Preterm LaborOct 21, 2026NCT07840235
Studies
Recruiting first, then most recently updated. Showing 50 of 242. Browse all 242 → or search them.
- Maternal Stress on Human Milk and Infant OutcomesRecruitingNCT04821544Not applicable1 country
- The Periviable GOALS Decision Support ToolRecruitingNCT05264779Not applicable1 country
- Cervical Stiffness in Women With Threatened Preterm LaborRecruitingNCT078402351 country
- Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve CareRecruitingNCT07738874Not applicable1 country
- Low Dose Aspirin vs Placebo in Prevention of Recurrent Spontaneous Preterm LabourNot yet recruitingNCT07745595Not applicable
- Short-Term Tocolysis in Preterm LaborNot yet recruitingNCT07696858
- Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum DatasetRecruitingNCT056857458 countries
- Pharmacokinetics and Placental Transfer of CaffeineRecruitingNCT07570121Phase 11 country
- A Clinical Trial on Safety in Pregnant Women and How Well the Infant is Protected Against RSV-associated Lower Respiratory Tract Infection When the Pregnant Woman Receives the Approved RSV Vaccine Compared to a Placebo.RecruitingNCT06955728Phase 34 countries
- Bed Rest With a Short Cervix on Preterm BirthNot yet recruitingNCT07577388Not applicable
- The Combined Effect of Magnesium, Palmitoylethanolamide, High-Molecular-weight Hyaluronic Acid, Vitamin B6, and Vitamin D in Preventing Preterm Birth:RecruitingNCT07305519Not applicable1 country
- The Combined First Trimester ScreeningRecruitingNCT070152031 country
- PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)RecruitingNCT072634901 country
- Evaluation of Cervical Invasion and Length in Placenta Accreta PatientsNot yet recruitingNCT07452185
- Single Dose of Antenatal Corticosteroids for Pregnancies at Risk of Preterm Delivery (SNACS)RecruitingNCT05114096Phase 41 country
- Prospective Data Bank Creation to Study Vaginal ConditionsRecruitingNCT018292041 country
- Development and Clinical Evaluation of an Innovative Medical Device to Predict Preterm Birth (PrediMAP)RecruitingNCT05586334Not applicable1 country
- PLatform for Adaptive Trials In Perinatal UnitS - [Core Protocol]Not yet recruitingNCT06461429Not applicable
- FB-CT2 Includes Two Prospective, Multi-centre Studies With a Medical Device in Hospital Settings: a Randomized, Dual-arm, Open-label Pilot Study in Spain, Followed by a Single-arm, Non-randomized, Open-label International Pivotal StudyRecruitingNCT06968364Not applicable1 country
- Urinary Infection in Pregnant Women with Urinary InfectionRecruitingNCT067521611 country
- Sleep Improvement Therapy Affects Pregnancy Outcomes in Chinese Singletons and Twins by Improving Sleep QualityEnrolling by invitationNCT06687044Not applicable1 country
- Effects of Kangaroo Care on Circadian Rhythm, Growth and Physiological EffectsNot yet recruitingNCT06589349Not applicable1 country
- Low Dose Antenatal Corticosteroids for Late Preterm DeliveryRecruitingNCT05698966Not applicable1 country
- Selected Immunological Indicators and Microbiota in Patients With Premature Birth and PreeclampsiaRecruitingNCT062812621 country
- Cervical Volume and Prediction of Preterm LaborNot yet recruitingNCT06190496
- Nifedipine Plus Magnesium Sulfate Versus Magnesium Sulfate for Very Early Preterm TocolysifsRecruitingNCT05345132Not applicable1 country
- Labor Status Monitor for Diagnosing True vs False Labor in Preterm PatientsRecruitingNCT061572031 country
- Cervical Softening and the Prediction of Preterm BirthRecruitingNCT054773811 country
- Adjunctive Vaginal Progesterone in Management of Preterm LaborRecruitingNCT05997563Phase 41 country
- Effect Of Azithromycin in Women at Risk of Preterm LabourNot yet recruitingNCT05971654Phase 2/31 country
- Azithromycin to Improve Latency in Exam Indicated Cerclage Control TrialRecruitingNCT05132829Phase 41 country
- Cyclin-dependent Kinase Inhibitor 2A (Placental Senescence Marker) on Labor-related SignalsNot yet recruitingNCT05864066
- Impact of Threatened Preterm Labour in Fetal Cardiovascular and Metabolic Programming (SHs)RecruitingNCT056706651 country
- Metformin to Prevent Preterm Birth in Twin PregnancyNot yet recruitingNCT05412056Phase 2/3
- Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGARecruitingNCT04047849Phase 41 country
- Vaginal Indomethacin for Preterm LaborNot yet recruitingNCT04404686Phase 2/3
- Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm LaborCompletedNCT05469984Not applicable1 country
- Oral Nifedipine vs Vaginal Progesterone for Prolonging Pregnancy in Preterm LaborCompletedNCT07865949Phase 41 country
- Music Therapy in the Threat of Premature BirthCompletedNCT05602883Not applicable1 country
- Is the Vaginal Microbiome and Metabolome Associated With Spontaneous Preterm Birth (sPTB) in Multiple Pregnancies?Active, not recruitingNCT060536971 country
- Fetal Brain Growth - Pilot StudyCompletedNCT059944431 country
- Analyze Changes in Respiratory Rate When Using the Scare RespiratorCompletedNCT04584814Not applicable1 country
- Phospholipase A2 Producing Bacteria and Pre-Term LaborCompletedNCT008555431 country
- Uterine Artery Doppler Indices and Uterocervical Angle Measurment in Prediction of Preterm LaborCompletedNCT073361731 country
- Hippo-YAP Pathway and Related miRNAs in Preterm BirthCompletedNCT076954671 country
- Threatened Preterm Labour: Vaginal Progesterone Versus NifedipineCompletedNCT07649668Phase 41 country
- Impact of Age at Conization on Obstetrical Outcome: A Case-Control StudyCompletedNCT057651881 country
- Maternal Serum Osteopontin Levels in Pregnant Women Diagnosed With PPROMCompletedNCT076263851 country
- Omega-3 Fatty Acids for Smoking Cessation in PregnancyCompletedNCT04417595Phase 21 country
- Prediction of Preterm Delivery With Serial Cervical Length Measurements After Threatened Preterm LaborCompletedNCT050441431 country