Drug
Pentostatin clinical trials
Also written Nipent, Deoxycoformycin, CI-825 and PD-81565.
- studies test it
- 44
- open now
- 1
- in phase 3
- 2
- first study started
- 1994
Keep track of what changes. Save the Pentostatin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
44 studies that test it; most in 2005 (7)
| Year | Studies |
|---|---|
| 1994 | 1 |
| 1997 | 1 |
| 1998 | 1 |
| 2000 | 4 |
| 2002 | 3 |
| 2003 | 5 |
| 2004 | 2 |
| 2005 | 7 |
| 2006 | 2 |
| 2007 | 2 |
| 2008 | 4 |
| 2009 | 1 |
| 2010 | 3 |
| 2011 | 3 |
| 2014 | 1 |
| 2017 | 1 |
| 2018 | 1 |
| 2021 | 1 |
| 2024 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 12
- Phase 2
- 37
- Phase 3
- 2
- Phase 4
- 1
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
- Lymphoma
- 11
Who runs them
Industry 4 · Other 40
M.D. Anderson Cancer Center (4) · National Cancer Institute (NCI) (3) · National Heart, Lung, and Blood Institute (NHLBI) (3) · Eastern Cooperative Oncology Group (3) · Mayo Clinic (3) · Memorial Sloan Kettering Cancer Center (3) · University of Nebraska (2) · Ohio State University Comprehensive Cancer Center (2)
Often tested with
Tested in the same studies.
Cyclophosphamide (18) · Rituximab (13) · Alemtuzumab (6) · Mycophenolic Acid (4) · Methotrexate (4) · Ofatumumab (3) · Bendamustine (2) · Sirolimus (2)
Studies
Open first, then newest update. How each study uses Pentostatin is read from its arms, and is right about nine times in ten.
Testing it · 44
- A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic AnemiaRecruitingPhase 1City of Hope Medical CenterNCT05757310Written as Pentostatin
- Randomized Phase II Trial of Rituximab With Either Pentostatin or Bendamustine for Multiply Relapsed or Refractory Hairy Cell LeukemiaActive, not recruitingPhase 2National Cancer Institute (NCI)NCT01059786Written as Pentostatin
- Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant FailureActive, not recruitingPhase 2National Heart, Lung, and Blood Institute (NHLBI)NCT02105766Written as Pentostatin
- Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell DiseaseActive, not recruitingPhase 1/2National Heart, Lung, and Blood Institute (NHLBI)NCT03077542Written as Pentostatin
- Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationActive, not recruitingPhase 2National Cancer Institute (NCI)NCT03663933Written as Pentostatin
- Combination of Pentostatin, Bendamustine and Ofatumumab for Treatment of Chronic Lymphocytic Leukemia and LymphomaTerminatedPhase 1Sidney Kimmel Cancer Center at Thomas Jefferson UniversityNCT01352312Written as Pentostatin
- Dose-finding Study Using Pentostatin for Injection in the Treatment of Steroid-refractory aGvHDTerminatedPhase 1/2Astex Pharmaceuticals, Inc.NCT00032773Written as pentostatin for injection
- Safety and Efficacy of Pentostatin and Low Dose TBI With Allogenic Peripheral Blood Stem Cell TransplantCompletedPhase 2University of NebraskaNCT00571662Written as Pentostatin
- Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological CancerWithdrawnPhase 1/2University of NebraskaNCT00816413Written as pentostatin
- Pentostatin, Cyclophosphamide, and Rituximab Followed By Campath-1H in Patients With Relapsed or Refractory B-Cell CLLCompletedPhase 2Eastern Cooperative Oncology GroupNCT00074282Written as pentostatin
- Reduced-Intensity Regimen Before Donor Bone Marrow Transplant in Treating Patients With Myelodysplastic SyndromesCompletedPhase 2Eastern Cooperative Oncology GroupNCT00045305Written as Pentostatin
- Reduced-Intensity Regimen Before Allogeneic Transplant for Patients With Relapsed Non-Hodgkin's or Hodgkin's LymphomaTerminatedPhase 2Eastern Cooperative Oncology GroupNCT00057954Written as Pentostatin
- Evaluation of the Safety and Efficacy of Nipent, Cytoxan, and RituxanCompletedPhase 2M.D. Anderson Cancer CenterNCT00496873Written as Nipent
- DCF Combined With Camrelizumab in the Treatment of Esophageal CancerStatus unknownNot applicableXijing HospitalNCT05050760Written as DCF
- Pentostatin in Treating Patients With Refractory Chronic Graft-Versus-Host DiseaseCompletedPhase 2Alliance for Clinical Trials in OncologyNCT00074035Written as pentostatin
- Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302)CompletedPhase 2National Heart, Lung, and Blood Institute (NHLBI)NCT00224874Written as Pentostatin
- Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell TransplantCompletedPhase 2Fred Hutchinson Cancer CenterNCT00096161Written as Pentostatin
- Rituximab, Pentostatin, Cyclophosphamide, and Lenalidomide in Treating Patients With Previously Untreated B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaCompletedPhase 2Mayo ClinicNCT00602836Written as Pentostatin
- SS1P and Pentostatin Plus Cyclophosphamide for MesotheliomaCompletedPhase 1/2National Cancer Institute (NCI)NCT01362790Written as Pentostatin
- A Study Of Deoxycoformycin(DCF)/Pentostatin In Lymphoid MalignanciesCompletedPhase 2M.D. Anderson Cancer CenterNCT00038025Written as Deoxycoformycin (DCF)
See all 44 studies that test Pentostatin →
Given in every arm · 4 — Pentostatin is usual care beside what is tested
- A Blood Stem Cell Transplant for Sickle Cell DiseaseActive, not recruitingPhase 1City of Hope Medical CenterNCT03249831Written as Pentostatin
- Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney CancerCompletedPhase 2National Cancer Institute (NCI)NCT00923845Written as Pentostatin
- Pentostatin, Cyclophosphamide, and Rituximab With or Without Bevacizumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaCompletedPhase 2Mayo ClinicNCT00816595Written as pentostatin
- A Trial of Extracorporeal Photopheresis, Pentostatin, and Total Body Irradiation in Patients Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation for the Treatment of MalignanciesCompletedPhase 2Yale UniversityNCT00402714Written as Pentostatin
As the comparator · 1 — what is tested is compared with Pentostatin
Codes
What other systems call Pentostatin · ClinicalTrials.gg INT008479
- MeSH (NLM) D015649PentostatinConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 395575MZO7PENTOSTATINConfirmed FDA, NLM, Wikidata
- RxNorm 8011Confirmed FDA, Wikidata
- Wikidata Q425470pentostatinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C732PentostatinOne source FDA
- DrugBank DB00552One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D015649 | Pentostatin | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 395575MZO7 | PENTOSTATIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 8011 | — | Confirmed FDA, Wikidata |
| Wikidata | Q425470 | pentostatin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C732 | Pentostatin | One source FDA |
| DrugBank | DB00552 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.