Bronchiolitis Obliterans Syndrome clinical trials
The registry lists 714 studies for Bronchiolitis Obliterans Syndrome across more than 10 countries. 128 are recruiting or about to start. 243 of them are mainly about Bronchiolitis Obliterans Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
ClinicalTrials.gov finds 783 studies for Bronchiolitis Obliterans Syndrome. How that becomes 714 here
This page counts the studies the registry files under Bronchiolitis Obliterans Syndrome, and those it files under no condition that list Bronchiolitis Obliterans Syndromethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 783Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −75Match it another way21 name it in the title and 54 by a synonym or other text the search reads.
- 708Counted here and found by its search1 of them list Bronchiolitis Obliterans Syndrome in their own words; the registry filed them under no condition.
- +6
Counted here, but its search does not find them
- Study of the Safety and Efficacy of Ruxolitinib Cream for Non-Sclerotic Chronic Cutaneous Graft-Versus-Host DiseaseNCT03954236
- Tacrolimus Toothpaste for Management of Oral Chronic Graft vs. Host Disease (cGVHD)NCT06638879
- Topical Dexamethasone and Tacrolimus for the Treatment of Oral Chronic Graft-Versus-Host DiseaseNCT00686855
- Observational Cohort Study on Ocular Chronic Graft-Versus-Host DiseaseNCT07794800
- UVB Phototherapy Treatment of Oral Chronic GVHDNCT00374257
- Safety and Efficacy of Efavaleukin Alfa in Subjects With Steroid Refractory Chronic Graft Versus Host DiseaseNCT03422627
- 714The count on this page
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Status
Who runs them
Novartis Pharmaceuticals (17) · Hoffmann-La Roche (12) · Incyte Corporation (11) · Dana-Farber Cancer Institute (11) · Fred Hutchinson Cancer Center (11) · National Cancer Institute (NCI) (10) · AstraZeneca (9) · Pfizer (9)
What is being tested here
Drugs under test in Bronchiolitis Obliterans Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Belumosudil | 7 | 2 | 14 |
| Axatilimab | 5 | 3 | 10 |
| Ruxolitinib | 3 | 2 | 11 |
| Cyclophosphamide | 2 | 1 | 5 |
| Entecavir | 2 | 0 | 2 |
| Azithromycin | 1 | 2 | 4 |
| Asciminib | 1 | 0 | 3 |
| Fostamatinib | 1 | 0 | 3 |
| JAK2 Inhibitor TQ05105 | 1 | 0 | 2 |
| Butylene glycol | 1 | 0 | 1 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 7 open · JAK inhibitors 4 open · Alkylating agents 2 open · Local anesthetics 2 open · Corticosteroids 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026A Long-term Extension Study of PCI-32765 (Ibrutinib) · Phase 3 · Janssen Research & Development, LLC
- Mar 2027An Efficacy and Safety Study of DFL24498 in the Treatment of AKC · Phase 3 · Dompé Farmaceutici S.p.A
- Apr 2027Extracorporeal Photopheresis for Medicare Recipients of Lung Allografts · Phase 3 · Washington University School of Medicine
- Sep 2027A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease · Phase 3 · Incyte Corporation
- Nov 2027Evaluation of the Efficacy of Azithromycin in Idiopathic Purulent Oedematous Sinusitis in Adults · Phase 3 · Centre Hospitalier Intercommunal Creteil
- Nov 2026HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical Therapy · Ömer Faruk Okumuş
- Dec 2026Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD - a Pilot Study · Karolinska Institutet
- Dec 2026LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome. · Steven Hays, MD
- Dec 2026Tele-Palliative Care Intervention for Patients With Chronic Graft-Versus-Host Disease · Massachusetts General Hospital
- Dec 2026Study on 30 Outpatients With Chronic Migraine Treated With Well-Being Therapy or With a Control Therapy · University of Florence
Who these studies take
Of the 100 Bronchiolitis Obliterans Syndrome studies recruiting now, 45 (45%) set no upper age limit and 45 (45%) stop at 75 or younger. 25 (25%) take children under 18. 3 (3%) are for women only and 0 (0%) for men only; 12 (12%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 15 (15%) | 14 (14%) |
| 18 | 91 (91%) | 88 (88%) |
| 30 | 93 (93%) | 90 (90%) |
| 40 | 95 (95%) | 92 (92%) |
| 50 | 93 (93%) | 90 (90%) |
| 65 | 89 (89%) | 87 (87%) |
| 75 | 62 (62%) | 60 (60%) |
| 85 | 48 (48%) | 46 (46%) |
Across all 714 studies, recruiting or not: 37% stop at 75 or younger and 26% at 65; 18% take children; 2% are for women only and 1% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Bronchiolitis Obliterans Syndrome studies take
Of 63 phase 2 interventional studies under Bronchiolitis Obliterans Syndrome, half reached primary completion within 35 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 47 mo18–65 · 22 studies | — | — |
| Phase 1/2 | 64 mo37–87 · 24 studies | — | — |
| Phase 2 | 35 mo23–58 · 63 studies | — | 43 mo27–70 · 38 studies |
| Phase 3 | 34 mo19–62 · 30 studies | — | — |
| Phase 4 | 22 mo17–79 · 16 studies | — | — |
| Interventional, no phase | 22 mo11–54 · 122 studies | — | 21 mo11–50 · 110 studies |
| Observational | 40 mo20–62 · 57 studies | — | 42 mo15–75 · 49 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting4
- A Study to Investigate the Efficacy and Safety of Belumosudil Compared With Best Available Therapy in Participants Aged 12 Years or Older With Chronic Graft-versus-host DiseaseNov 6, 2026NCT07771439
- Evaluation of the Short-term Effectiveness of Spinal Manipulation to Treat Acute and Subacute Low Back Pain.Oct 23, 2026NCT07403500
- A Preliminary Clinical Study on the Efficacy of Cyclophosphamide and Sirolimus Combined With VIC-1911 in Preventing Graft-versus-Host Disease After Haploidentical Stem Cell Transplantation in ChildrenOct 20, 2026NCT07350057
- Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host DiseaseOct 16, 2026NCT07733141
Stopped1
- Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-DiseaseSuspendedOct 16, 2026NCT06046248
Newly registered5
- A New ECP Protocol for the Treatment of cGVHDNov 5, 2026NCT07918547
- Multimodal Manual Therapy vs. Maitland Mobilization for Chronic Non-Specific Neck PainNov 3, 2026NCT07912099
- Evaluating and Promoting Resilience in Adolescents With Tourette SyndromeOct 30, 2026NCT07905898
- A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB)Oct 27, 2026NCT07897448
- Comparision of Enzymatic and Active Salt ToothpasteOct 19, 2026NCT07880483
Studies
Recruiting first, then most recently updated. Showing 50 of 714. Browse all 714 → or search them.
- Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CPRecruitingNCT07354074Phase 217 countries
- A Study to Investigate Safety of Belumosudil in Participants Aged 12 Years and Above, With Chronic Graft-versus-host Disease (cGVHD)Not yet recruitingNCT07135973Phase 4
- Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male ParticipantsNot yet recruitingNCT07726914Phase 1
- Evaluation of the Quality of Life Induced by the Cinnamon Anti-odor Dressing in Patients With Malodorous WoundsRecruitingNCT05685628Not applicable1 country
- Evaluation of Patients With Immune Function AbnormalitiesRecruitingNCT001289731 country
- Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic MalignanciesRecruitingNCT04959175Phase 1/21 country
- Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic MalignanciesRecruitingNCT05327023Phase 1/21 country
- A Study to Investigate the Efficacy and Safety of Belumosudil Compared With Best Available Therapy in Participants Aged 12 Years or Older With Chronic Graft-versus-host DiseaseRecruitingNCT07771439Phase 32 countries
- A New ECP Protocol for the Treatment of cGVHDNot yet recruitingNCT07918547Not applicable1 country
- Effect of Anomia Rehabilitation Combined With Metacognitive Training in Patients With Chronic Vascular AphasiaRecruitingNCT06930131Not applicable1 country
- Ex Vivo-Expanded Regulatory T Cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic GVHDRecruitingNCT06991361Phase 11 country
- Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune DisordersRecruitingNCT06434363Phase 1/21 country
- A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host DiseaseRecruitingNCT06585774Phase 313 countries
- Evaluating and Promoting Resilience in Adolescents With Tourette SyndromeNot yet recruitingNCT07905898Not applicable1 country
- Uncovering the Mechanism of Pain Relief by Peripheral Transcutaneous Magnetic StimulationRecruitingNCT07199361Not applicable1 country
- A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB)Not yet recruitingNCT07897448Phase 1/2
- Evaluation of the Short-term Effectiveness of Spinal Manipulation to Treat Acute and Subacute Low Back Pain.RecruitingNCT07403500Not applicable1 country
- A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)RecruitingNCT06615050Phase 31 country
- Dental Cleaning to Prevent Chronic Graft-Versus-Host DiseaseRecruitingNCT07535008Not applicable1 country
- A Preliminary Clinical Study on the Efficacy of Cyclophosphamide and Sirolimus Combined With VIC-1911 in Preventing Graft-versus-Host Disease After Haploidentical Stem Cell Transplantation in ChildrenRecruitingNCT07350057Phase 11 country
- Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host DiseaseRecruitingNCT07733141Not applicable1 country
- Chronic Exogenous Ketosis in HFpEFEnrolling by invitationNCT06937320Phase 21 country
- A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)RecruitingNCT07124078Phase 26 countries
- Observational Study for Patients at Risk for Chronic Graft-Versus-Host DiseaseRecruitingNCT059195111 country
- Axatilimab for Sclerotic Chronic Graft-versus-Host DiseaseRecruitingNCT07011810Phase 21 country
- Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEADRecruitingNCT07348783Not applicable1 country
- A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK)RecruitingNCT07116031Phase 213 countries
- An Efficacy and Safety Study of DFL24498 in the Treatment of AKCRecruitingNCT07395232Phase 33 countries
- Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host DiseaseRecruitingNCT05996627Phase 21 country
- Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke FatigueRecruitingNCT05584124Phase 21 country
- Mobile Health Self-Management and Support System for Chronic and Complex Health ConditionsRecruitingNCT02592291Not applicable1 country
- Observational Cohort Study on Ocular Chronic Graft-Versus-Host DiseaseRecruitingNCT077948001 country
- Evaluation of Belumosudil Whole Tablets vs. Crushed Tablets Pharmacokinetics in Patients Suffering From Chronic GvHDRecruitingNCT07127926Phase 11 country
- A Clinical Trial of TQ05105 Tablets in the Treatment of Chronic Graft-versus-host DiseaseRecruitingNCT06300320Phase 21 country
- Anrikefon vs Nalfurafine for Sleep Quality in Hemodialysis Patients With CKD-aPRecruitingNCT07380113Phase 41 country
- Efficacy of an Anti-TSLP Monoclonal Antibody in the Management of Chronic Bronchial Disease Induced by Bronchiolitis Obliterans Syndrome in Allogeneic Hematopoietic Stem Cells Transplantation RecipientsRecruitingNCT07771855Phase 21 country
- Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung TransplantRecruitingNCT05654922Phase 31 country
- Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic TherapyRecruitingNCT06660355Phase 21 country
- Efficacy of Bee Venom Phonophoresis in Treating Chronic Sinusitis:Not yet recruitingNCT07151313Not applicable1 country
- Shortwave Infrared Surgical Imaging Device StudyEnrolling by invitationNCT077444251 country
- A Clinical Study Evaluating the Pharmacokinetic Characteristics and Safety of AHB-137 Injection in Participants With Mild to Moderate Liver Dysfunction and Those With Normal Liver Function.RecruitingNCT07600788Phase 11 country
- NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health DisparitiesRecruitingNCT06810622Not applicable1 country
- Study of AHB-171 in Chronic Hepatitis B ParticipantsRecruitingNCT07630727Phase 21 country
- Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD)RecruitingNCT06247150Not applicable1 country
- Autologous Adipose-Derived Mesenchymal Stem Cells for Chronic Traumatic Brain InjuryRecruitingNCT05951777Phase 21 country
- UTSW NORC Pilot Spinal Cord Injury Dietary ProgramRecruitingNCT06924177Not applicable1 country
- A Multicentre Randomised Controlled Trial Evaluating the Efficacy of the SMILE™ Module for Improving Short-term Periodontal Outcomes, Compliance, and Acceptability Among Clinical Dental StudentsNot yet recruitingNCT07702383Not applicable1 country
- Plasma and Radiologic Biomarkers of Response to ECP in Lung Transplant Recipients With CLADRecruitingNCT074348691 country
- Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With GingivitisNot yet recruitingNCT076897861 country
- Dry Dynamic Cupping vs Instrument-Assisted Soft Tissue Mobilization for Chronic Myofascial Low Back PainRecruitingNCT07685340Not applicable1 country