Hematologic Neoplasms clinical trials
The registry lists 1,444 studies for Hematologic Neoplasms across more than 10 countries. 420 are recruiting or about to start. 982 of them are mainly about Hematologic Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 2 narrower conditions too, such as Polycythemia Vera: 1,754 studies, 479 open.
ClinicalTrials.gov finds 14,387 studies for Hematologic Neoplasms. How that becomes 1,442 here
This page counts the studies the registry files under Hematologic Neoplasms, and those it files under no condition that list Hematologic Neoplasmsthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 14,387Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −309Filed under a narrower condition, counted on its own pagePolycythemia Vera 272 · Blastic Plasmacytoid Dendritic Cell Neoplasm 37
- −52List Hematologic Neoplasms as a condition, but the registry did not file them under itMost often written as “Transplant-Related Hematologic Malignancy” (7), “Advanced Hematologic Malignancies” (6), and “Lymphoid Hematological Malignancies” (4). The registry filed 22 of them under no condition at all, and the others under other conditions only, most often Leukemia, Myeloid, Acute (8) and Recurrence (8).
- −12,584Match it another way616 name it in the title, 11 in a keyword, and 11,957 by a synonym or other text the search reads.
- 1,442The count on this page
Get an email when these change. Save the Hematologic Neoplasms studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
M.D. Anderson Cancer Center (99) · National Cancer Institute (NCI) (60) · Fred Hutchinson Cancer Center (28) · City of Hope Medical Center (25) · St. Jude Children's Research Hospital (22) · Novartis Pharmaceuticals (17) · Dana-Farber Cancer Institute (16) · Assistance Publique - Hôpitaux de Paris (16)
What is being tested here
Drugs under test in Hematologic Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cyclophosphamide | 17 | 3 | 52 |
| Fludarabine | 10 | 1 | 40 |
| Venetoclax | 7 | 1 | 9 |
| Thymoglobulin | 4 | 1 | 9 |
| Azacitidine | 4 | 2 | 9 |
| Busulfan | 3 | 1 | 25 |
| Melphalan | 3 | 1 | 16 |
| Bortezomib | 3 | 1 | 10 |
| Trametinib | 3 | 2 | 8 |
| Thiotepa | 3 | 0 | 7 |
Drug classes tested here Alkylating agents 20 open · Antimetabolites 17 open · Tyrosine kinase inhibitors (TKIs) 17 open · Immune checkpoint inhibitors 5 open · Proteasome inhibitors 3 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Feb 2027Platelet Transfusions in Hematopoietic Stem Cell Transplantation (The PATH III Trial) · Phase 3 · Ottawa Hospital Research Institute
- Mar 2027Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia · Phase 3 · Quetzal Therapeutics
- Apr 2027Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or Extension · Phase 3 · Monash University
- Apr 2027Influenza Vaccination Strategy for Patients With Hematologic Malignancy · Phase 3 · Asan Medical Center
- Jun 2027An Extension Study for Patients Previously Enrolled in Studies With Pelabresib · Phase 3 · Novartis Pharmaceuticals
- Aug 2027Fentanyl Buccal Tablet or Morphine for Exertional Dyspnea in Cancer Patients · Phase 3 · M.D. Anderson Cancer Center
- Nov 2026Outcomes After Chimeric Antigen Receptor Therapy and Radiation Therapy for Hematologic Malignancies · M.D. Anderson Cancer Center
- Nov 2026Atezolizumab in Treating Patients With Cancer Following Adoptive Cell Transfer · National Cancer Institute (NCI)
- Nov 2026Progressive Relaxation and Psychoeducation in Patients With Hematological Malignancies · Necmettin Erbakan University
- Nov 2026A Study of the Effect of Laughter Therapy on the Mental Health and Quality of Survival of Hematopoietic Stem Cell Transplant Patients · Institute of Hematology & Blood Diseases Hospital, China
Who these studies take
Of the 313 Hematologic Neoplasms studies recruiting now, 208 (66%) set no upper age limit and 78 (25%) stop at 75 or younger. 80 (26%) take children under 18. 1 (<1%) are for women only and 0 (0%) for men only; 34 (11%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 63 (20%) | 63 (20%) |
| 18 | 292 (93%) | 291 (93%) |
| 30 | 292 (93%) | 291 (93%) |
| 40 | 289 (92%) | 288 (92%) |
| 50 | 289 (92%) | 288 (92%) |
| 65 | 287 (92%) | 286 (91%) |
| 75 | 264 (84%) | 263 (84%) |
| 85 | 225 (72%) | 224 (72%) |
Across all 1,444 studies, recruiting or not: 27% stop at 75 or younger and 15% at 65; 24% take children; <1% are for women only and <1% for men only; 7% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hematologic Neoplasms studies take
Of 159 phase 1 interventional studies under Hematologic Neoplasms, half reached primary completion within 51 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 51 mo28–78 · 159 studies | 43 mo30–78 · 95 studies | 56 mo28–88 · 64 studies |
| Phase 1/2 | 76 mo51–127 · 64 studies | — | — |
| Phase 2 | 57 mo40–94 · 136 studies | — | 59 mo42–95 · 114 studies |
| Phase 3 | 58 mo42–81 · 41 studies | — | — |
| Interventional, no phase | 40 mo21–125 · 191 studies | — | 40 mo21–125 · 185 studies |
| Observational | 74 mo34–322 · 186 studies | — | 74 mo35–322 · 164 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Started recruiting8
- A Clinical Trial of MK-1045 in People With B-cell Cancer (MK-1045-006)Nov 4, 2026NCT07709000
- Study of ORM-1153 in Acute Myeloid Leukemia (AML) With CD123 ExpressionNov 2, 2026NCT07809906
- Virtual Reality Intervention to Improve Comfort in Hospitalized Hematology PatientsNov 2, 2026NCT07894601
- Prophylactic DLI-X for Leukemia Relapse After HCTOct 29, 2026NCT07254793
- Safety and Tolerability of REGN17235 in Adult Participants With Clonal Cytopenia of Undetermined Significance and Low-Risk Myelodysplastic Syndrome With SF3B1 MutationOct 27, 2026NCT07753148
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- Role of Viscoelastometric Testing in the Development and Validation of a Clinical-biological Score for Predicting Bleeding in Patients With Malignant Haematological Disorders and Severe ThrombocytopeniaOct 22, 2026NCT07653672
- A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS)Oct 16, 2026NCT06782373
- Addition of Venetoclax to Combined Hematopoietic Stem Cell and Kidney TransplantationOct 14, 2026NCT07358195
Results posted1
- Acalabrutinib for the Treatment of Chronic Graft Versus Host DiseaseOct 14, 2026NCT04198922
Stopped1
- Hu8F4 in Treating Patients With Advanced Hematologic MalignanciesTerminatedNov 4, 2026NCT02530034
Newly registered12
- High-Dose Versus Standard-Dose Influenza Vaccine in Patients With Hematologic Malignancies Receiving B-Cell-Depleting TherapyNov 9, 2026NCT07926217
- Lanoracopan to Prevent Acute GVHD Following Haploidentical Peripheral Blood Stem Cell Transplantation: A Prospective Multicenter Single-Arm Exploratory StudyNov 9, 2026NCT07926698
- A Study to Assess the Pharmacokinetics and Safety of Revumenib in Participants With Advanced Cancer and Hepatic or Renal ImpairmentNov 6, 2026NCT07923071
- MACE and BTK InhibitorsNov 6, 2026NCT07923162
- Middle East Study of Infections in Patients With Hematological MalignanciesOct 28, 2026NCT07900542
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- A Study of MDSY-1240, a STAT3 Degrader, for the Treatment of Hematologic Malignancies and Advanced Solid TumorsOct 27, 2026NCT07899632
- Virtual Reality Intervention to Improve Comfort in Hospitalized Hematology PatientsOct 26, 2026NCT07894601
- Comprehensive Palliative Care After Stem Cell Transplantation: a Feasability StudyOct 26, 2026NCT07895693
- Phase 2 Study of Oral Epetraborole in Adults With Polycythemia VeraOct 23, 2026NCT07891533
- Symptom Monitoring and Management Intervention After CAR-TOct 21, 2026NCT07886190
- Effects of Resistance Training on Recovery During Hematopoietic Stem Cell TransplantationOct 14, 2026NCT07872813
- KATALYST-HEME-01: Study of the KAT6 Inhibitor MEN2312 in Heme MalignanciesOct 14, 2026NCT07873827
Studies
Recruiting first, then most recently updated. Showing 50 of 1,444. Browse all 1,444 → or search them.
- The Effect of COVID-19 Pandemic on Adolescent and Young Adult Cancer Patients and SurvivorsRecruitingNCT045513781 country
- A Clinical Trial of MK-1045 in People With B-cell Cancer (MK-1045-006)RecruitingNCT07709000Phase 23 countries
- The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell TransplantationRecruitingNCT05436418Phase 1/21 country
- Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)RecruitingNCT03486873Phase 351 countries
- Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood CancersNot yet recruitingNCT07524530Phase 21 country
- The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer DrugsRecruitingNCT05159245Phase 21 country
- High-Dose Versus Standard-Dose Influenza Vaccine in Patients With Hematologic Malignancies Receiving B-Cell-Depleting TherapyRecruitingNCT07926217Phase 21 country
- Lanoracopan to Prevent Acute GVHD Following Haploidentical Peripheral Blood Stem Cell Transplantation: A Prospective Multicenter Single-Arm Exploratory StudyNot yet recruitingNCT07926698Phase 2
- Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic MalignanciesRecruitingNCT04959175Phase 1/21 country
- Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...RecruitingNCT05470491Phase 1/21 country
- Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell TransplantRecruitingNCT068562261 country
- Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic MalignanciesRecruitingNCT05327023Phase 1/21 country
- Follow-Up Evaluation for Gene-Therapy-Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical TrialsEnrolling by invitationNCT023155991 country
- Screening for Hematology Branch ProtocolsEnrolling by invitationNCT000016201 country
- An Exploratory Study to Evaluate Immune Determinants of the Response to Adoptive Cell Therapy (ACT) in Solid and Hematologic TumorsRecruitingNCT05481502Not applicable1 country
- HMCT/CT2401: Abatacept GVHD Prophylaxis Following Omidubicel HCTRecruitingNCT06731504Early Phase 11 country
- MACE and BTK InhibitorsNot yet recruitingNCT07923162Phase 41 country
- A Study to Assess the Pharmacokinetics and Safety of Revumenib in Participants With Advanced Cancer and Hepatic or Renal ImpairmentNot yet recruitingNCT07923071Phase 1
- Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family MembersEnrolling by invitationNCT000710451 country
- Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer DetectionRecruitingNCT053340691 country
- Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side EffectsRecruitingNCT042420951 country
- Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell TherapyRecruitingNCT065794691 country
- Dose-Escalation/Expansion Study of iMagic in Relapsed/Refractory Hematologic MalignanciesNot yet recruitingNCT07802756Early Phase 11 country
- A Study of JNJ-95804306 for Relapsed or Refractory Hematological MalignanciesRecruitingNCT07572006Phase 17 countries
- A Study of Talquetamab in Participants With Relapsed or Refractory Multiple MyelomaRecruitingNCT04634552Phase 211 countries
- Gene Therapy Follow-up Protocol for People Previously Enrolled in CAR-T Cell StudiesEnrolling by invitationNCT024737571 country
- Virtual Reality Intervention to Improve Comfort in Hospitalized Hematology PatientsRecruitingNCT07894601Not applicable1 country
- Study of ORM-1153 in Acute Myeloid Leukemia (AML) With CD123 ExpressionRecruitingNCT07809906Phase 11 country
- Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic MalignanciesRecruitingNCT06904066Phase 11 country
- Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT)RecruitingNCT05322850Phase 1/21 country
- Middle East Study of Infections in Patients With Hematological MalignanciesRecruitingNCT079005425 countries
- Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic LeukemiaRecruitingNCT07504458Phase 35 countries
- Mosaic Trial for Stem Cell Transplant RecipientsRecruitingNCT06960993Not applicable1 country
- Micro Assays for HemATology Malignancies Antibody TreatmentNot yet recruitingNCT07018310Not applicable1 country
- Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a SolutionRecruitingNCT061318011 country
- Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or VenetoclaxRecruitingNCT057241211 country
- Prophylactic DLI-X for Leukemia Relapse After HCTRecruitingNCT07254793Phase 11 country
- Avera Cancer Sequencing and Analytics Protocol (ASAP)RecruitingNCT051420331 country
- HEME Home Transfusion ProgramRecruitingNCT06487247Not applicable1 country
- Safety and Tolerability of REGN17235 in Adult Participants With Clonal Cytopenia of Undetermined Significance and Low-Risk Myelodysplastic Syndrome With SF3B1 MutationRecruitingNCT07753148Phase 11 country
- A Study of MDSY-1240, a STAT3 Degrader, for the Treatment of Hematologic Malignancies and Advanced Solid TumorsNot yet recruitingNCT07899632Phase 1/2
- Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)RecruitingNCT04728893Phase 222 countries
- Comprehensive Palliative Care After Stem Cell Transplantation: a Feasability StudyRecruitingNCT07895693Not applicable1 country
- A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.RecruitingNCT06697184Phase 1/26 countries
- Phase 2 Study of Oral Epetraborole in Adults With Polycythemia VeraNot yet recruitingNCT07891533Phase 21 country
- Symptom Monitoring and Management Intervention After CAR-TNot yet recruitingNCT07886190Not applicable1 country
- Why Patients Decline or Are Being Deemed Ineligible to Receive Home-based Treatment: a Mixed Methods StudyNot yet recruitingNCT076342631 country
- Follow-Up for Study Participants Treated With an Allogeneic CAR T Cell ProductEnrolling by invitationNCT069256851 country
- Role of Viscoelastometric Testing in the Development and Validation of a Clinical-biological Score for Predicting Bleeding in Patients With Malignant Haematological Disorders and Severe ThrombocytopeniaRecruitingNCT076536721 country
- Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor MicroenvironmentEnrolling by invitationNCT056009331 country