Lymphoproliferative Disorders clinical trials
The registry lists 216 studies for Lymphoproliferative Disorders across more than 10 countries. 49 are recruiting or about to start. 34 of them are mainly about Lymphoproliferative Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 53 narrower conditions too, such as Multiple Myeloma: 15,145 studies, 3,324 open.
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
National Cancer Institute (NCI) (12) · Baylor College of Medicine (9) · Seagen Inc. (7) · National Institute of Allergy and Infectious Diseases (NIAID) (6) · Cancer Research UK (6) · Mayo Clinic (5) · Children's Oncology Group (5) · Amgen Research (Munich) GmbH (5)
What is being tested here
Drugs under test in Lymphoproliferative Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Pacritinib | 2 | 0 | 3 |
| Dabrafenib | 2 | 2 | 2 |
| Trametinib | 2 | 2 | 2 |
| Alectinib | 2 | 2 | 2 |
| Atezolizumab | 2 | 2 | 2 |
| Entrectinib | 2 | 2 | 2 |
| Cyclophosphamide | 1 | 0 | 10 |
| Prednisone | 1 | 0 | 4 |
| Etoposide | 1 | 0 | 2 |
| Doxorubicin | 1 | 0 | 2 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 6 open · Immune checkpoint inhibitors 3 open · Alkylating agents 1 open · Corticosteroids 1 open · Antimetabolites 14
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Feb 2027A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312) · Phase 3 · Acerta Pharma BV
- Dec 2026A Study of Venetoclax and Rituximab/Hyaluronidase Human in Relapsed/Refractory CLL · Georgetown University
- Dec 2026A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study · OriCell Therapeutics Co., Ltd.
- Dec 2026HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis · Center for International Blood and Marrow Transplant Research
- Dec 2026Epcoritamab for the Treatment of Relapsed or Refractory Post Transplant Lymphoproliferative Disorders · Timothy Voorhees
- Mar 2027A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma · Kelonia Therapeutics, Inc.
- Mar 2027Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE · Baylor College of Medicine
- Apr 2027Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD) · Jennifer Amengual
- May 2027Ultrasound to Detect Splenomegally in Patients With Isolated Thrombocytopenia · Assiut University
- Jun 2027A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases · Pierre Fabre Medicament
Who these studies take
Of the 39 Lymphoproliferative Disorders studies recruiting now, 28 (72%) set no upper age limit and 6 (15%) stop at 75 or younger. 18 (46%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (5%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 15 (38%) | 15 (38%) |
| 18 | 38 (97%) | 38 (97%) |
| 30 | 37 (95%) | 37 (95%) |
| 40 | 37 (95%) | 37 (95%) |
| 50 | 37 (95%) | 37 (95%) |
| 65 | 38 (97%) | 38 (97%) |
| 75 | 36 (92%) | 36 (92%) |
| 85 | 33 (85%) | 33 (85%) |
Across all 216 studies, recruiting or not: 24% stop at 75 or younger and 15% at 65; 39% take children; 0% are for women only and 0% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Lymphoproliferative Disorders studies take
Of 30 phase 2 interventional studies under Lymphoproliferative Disorders, half reached primary completion within 144 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 144 mo57–356 · 30 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Results posted1
- Immune Disorder HSCT ProtocolOct 27, 2026NCT01821781
Studies
Recruiting first, then most recently updated. Showing 50 of 216. Browse all 216 → or search them.
- Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomasRecruitingNCT03258567Phase 21 country
- Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of ImmunityRecruitingNCT04339777Phase 21 country
- Loncastuximab Tesirine and Rituximab as First-line Therapy in Patients With Post-transplant Lymphoproliferative Disorder (PLUTO)RecruitingNCT07573436Phase 1/21 country
- Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesRecruitingNCT02579967Phase 21 country
- Genetic Studies of Chronic Active Epstein-Barr DiseaseRecruitingNCT000325131 country
- Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic CancerRecruitingNCT011376431 country
- A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and ChemotherapyRecruitingNCT03394365Phase 39 countries
- Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)RecruitingNCT06052618Phase 21 country
- Establishing a Tumor Bank in Families With Multiple Lymphoproliferative MalignanciesRecruitingNCT001310141 country
- CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)RecruitingNCT03328078Phase 1/27 countries
- Understanding the Mechanisms of Clonal and Non-clonal Cytopenia Following CAR-T Therapy for Multiple Myeloma or CD19+ Lymphoproliferative Disorder (LPD)RecruitingNCT06630104Not applicable1 country
- Epcoritamab for the Treatment of Relapsed or Refractory Post Transplant Lymphoproliferative DisordersRecruitingNCT06672705Phase 11 country
- Virtual Rehabilitation for Cancer SurvivorsRecruitingNCT05898789Not applicable1 country
- A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple MyelomaRecruitingNCT07075185Phase 12 countries
- Project: Every Child for Younger Patients With CancerRecruitingNCT024022446 countries
- Recombinant Glycosylated Human Interleukin-7 (CYT107) for the Treatment of Kaposi Sarcoma in Participants With HIV and Immune Non-Response (REGIMENKS HIV)RecruitingNCT07308886Phase 21 country
- A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and LymphomasRecruitingNCT04104776Phase 1/27 countries
- DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.RecruitingNCT07440290Phase 2/31 country
- Pathogenesis of Hematologic MalignanciesEnrolling by invitationNCT017284021 country
- Evaluation of Lymphoma Prognosis and Survivorship in Recently Diagnosed Patients, LEO StudyEnrolling by invitationNCT049967061 country
- DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening ProtocolRecruitingNCT05722886Phase 2/31 country
- Registry of Older Patients With CancerRecruitingNCT011378251 country
- Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD)RecruitingNCT06954805Phase 21 country
- Comparison of Serratus Posterior Superior Intercostal Plane Block and Deep Serratus Anterior Plane Block After Video-Assisted Thoracoscopic SurgeryNot yet recruitingNCT07553195Not applicable1 country
- The OPAL Study: AVM0703 for Treatment of Lymphoid MalignanciesRecruitingNCT04329728Phase 1/21 country
- Tafasitamab and Rituximab for Front-Line Treatment of Post-Transplant Lymphoproliferative DisorderRecruitingNCT05786040Phase 21 country
- A Comprehensive Register Of Lymphoproliferative Disorders (ReLy)RecruitingNCT075193561 country
- Clonal Hematopoiesis of Immunological SignificanceNot yet recruitingNCT059698211 country
- EBV-AST Cell Injection for EBV-Associated Lymphoproliferative DisordersRecruitingNCT07450391Phase 1/21 country
- Feasibility of a Multi-omics Platform for Hematological MalignanciesRecruitingNCT07445438Not applicable1 country
- Chemogenomic Profiling in Hematological Malignancies (HEM-Profiling 2021)RecruitingNCT07445984Not applicable1 country
- Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALERecruitingNCT01555892Phase 11 country
- Acalabrutinib and Obinutuzumab for the Treatment of Previously Untreated Follicular Lymphoma or Other Indolent Non-Hodgkin LymphomasRecruitingNCT04883437Phase 21 country
- Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative NeoplasmsRecruitingNCT04858256Phase 21 country
- DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) DispositionRecruitingNCT05770102Phase 2/31 country
- DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive CancersRecruitingNCT05770037Phase 2/31 country
- DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers.RecruitingNCT05770544Phase 2/31 country
- T Cell Therapy of Opportunistic Cytomegalovirus InfectionRecruitingNCT02982902Early Phase 11 country
- Ultrasound to Detect Splenomegally in Patients With Isolated ThrombocytopeniaNot yet recruitingNCT07182760
- Application of PD-1 Inhibitors, Tenofovir, Chidamide, and Lenalidomide in Relapsed/Refractory EBV-associated Lymphoproliferative Disorders.Not yet recruitingNCT07133763Phase 1/2
- Pivotal, Clinical Study for the Accuracy Evaluation of the IdentiClone Dx TRG AssayNot yet recruitingNCT068765713 countries
- CAR-NK Cells Production and Expansion From Patients With Lympho or Myeloproliferative Disorders and From Healthy DonorsRecruitingNCT06727383Not applicable1 country
- Clinical Study of Therapeutic Immunological Agent for EBV Lymphoproliferative DiseasesNot yet recruitingNCT06666153Phase 11 country
- BCMA-GPRC5D CAR-T Therapy in Relapsed or Refractory Multiple MyelomaRecruitingNCT06644443Phase 1/21 country
- Remote Multichannel Monitoring of Patients With Chronic DIseAses Using Speech technoLogies Based On Artificial intelliGenceNot yet recruitingNCT06644339Not applicable1 country
- ISRT 20 Gy for Indolent Localized Gastrointestinal (GI)-LymphomaRecruitingNCT04097067Not applicable1 country
- A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL StudyRecruitingNCT06271252Phase 11 country
- Familial B-cell Lymphoproliferative DisordersNot yet recruitingNCT05718986
- Liquid Biopsy to Enable Diagnostics and Monitoring for Immune-mediated Lymphoproliferative DisordersRecruitingNCT058036161 country
- Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell LymphomaActive, not recruitingNCT03922724Phase 21 country