Drug
Mesna clinical trials
Also written Mesnex, Uromitexan, UCB 3983 and D-7093.
- studies test it
- 87
- open now
- 14
- in phase 3
- 8
- first study started
- 1991
Keep track of what changes. Save the Mesna studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
87 studies that test it; most in 2003 (5)
| Year | Studies |
|---|---|
| 1991 | 1 |
| 1992 | 2 |
| 1994 | 2 |
| 1995 | 1 |
| 1996 | 2 |
| 1997 | 1 |
| 1999 | 1 |
| 2000 | 1 |
| 2002 | 2 |
| 2003 | 5 |
| 2004 | 5 |
| 2005 | 3 |
| 2006 | 3 |
| 2007 | 5 |
| 2008 | 1 |
| 2009 | 3 |
| 2010 | 3 |
| 2011 | 1 |
| 2012 | 2 |
| 2013 | 4 |
| 2014 | 3 |
| 2015 | 4 |
| 2016 | 3 |
| 2017 | 3 |
| 2018 | 3 |
| 2019 | 4 |
| 2020 | 3 |
| 2021 | 5 |
| 2022 | 1 |
| 2023 | 2 |
| 2024 | 2 |
| 2025 | 3 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 23
- Phase 2
- 53
- Phase 3
- 8
- Phase 4
- 1
- No phase
- 12
What it is tested for
Each study’s main condition, where its own words name it.
- Lymphoma
- 12
Who runs them
Industry 1 · Other 86
St. Jude Children's Research Hospital (14) · M.D. Anderson Cancer Center (9) · National Cancer Institute (NCI) (6) · Northwestern University (6) · Masonic Cancer Center, University of Minnesota (5) · Children's Oncology Group (4) · Baylor College of Medicine (4) · Memorial Sloan Kettering Cancer Center (3)
Often tested with
Tested in the same studies.
Cyclophosphamide (63) · Fludarabine (30) · Filgrastim (28) · Etoposide (26) · Ifosfamide (20) · Rituximab (16) · Granulocyte Colony-Stimulating Factor (15) · Vincristine (13)
Studies
Open first, then newest update. How each study uses Mesna is read from its arms, and is right about nine times in ten.
Testing it · 87
- Haploidentical HCT for Severe Aplastic AnemiaRecruitingPhase 2St. Jude Children's Research HospitalNCT04558736Written as Mesna
- Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk OsteosarcomaRecruitingPhase 2St. Jude Children's Research HospitalNCT07428993Written as Mesna
- Study of CD19 Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ LeukemiaRecruitingPhase 1St. Jude Children's Research HospitalNCT04881240Written as Mesna
- CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and LymphomaRecruitingPhase 1St. Jude Children's Research HospitalNCT07257419Written as Mesna
- Autologous Stem Cell Transplantation in Patients With Systemic SclerosisRecruitingPhase 2Paul SzabolcsNCT03630211Written as Mesna
- A FIH, Phase I/IIa, Trial Assessing Feasibility of Administrations of TIL-based Immunotherapy in Patients With Metastatic CRC and PCRecruitingPhase 1/2CuraCell TX ABNCT07255664Written as Uromitexan
- CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)RecruitingPhase 1St. Jude Children's Research HospitalNCT04318678Written as Mesna
- CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic LeukemiaRecruitingPhase 1St. Jude Children's Research HospitalNCT06777979Written as Mesna
- BMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI)RecruitingPhase 2University of Illinois at ChicagoNCT04187105Written as Conditioning regimen with half-matched (haploidentical) stem cell transplant
- CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive LeukemiaRecruitingPhase 2St. Jude Children's Research HospitalNCT06847269Written as Mesna
- Stem Cell Transplantation in Crohn's DiseaseRecruitingPhase 1/2Cedars-Sinai Medical CenterNCT04224558Written as Mesna
- Modified R-MINE Regimen vs. R-GemOx Regimens on the Treatment of Late Relapsed DLBCLNot yet recruitingNot applicableThe First Affiliated Hospital with Nanjing Medical UniversityNCT07389356Written as Rituximab+Ifosfamide+Mesna+Mitoxantrone hydrochloride liposome+Etoposide
- CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological MalignanciesRecruitingPhase 1St. Jude Children's Research HospitalNCT06326463Written as Mesna
- IS-free Treg HaploHCTRecruitingPhase 1Dana-Farber Cancer InstituteNCT04678401Written as Mesna
- Concurrent Chemotherapy and Radiation Therapy for Newly Diagnosed Nasal NK Cell LymphomaActive, not recruitingPhase 2M.D. Anderson Cancer CenterNCT02106988Written as Mesna
- Therapy for Children With Advanced Stage NeuroblastomaCompletedPhase 2St. Jude Children's Research HospitalNCT01857934Written as mesna
- Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell LymphomaActive, not recruitingPhase 2Canadian Cancer Trials GroupNCT02436707Written as Mesna
- Liver Transplantation With Tregs at MGHCompletedPhase 1/2National Institute of Allergy and Infectious Diseases (NIAID)NCT03577431Written as mesna
- Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in AdultsActive, not recruitingPhase 3National Cancer Institute (NCI)NCT04530565Written as Mesna
- Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic MelanomaActive, not recruitingPhase 2M.D. Anderson Cancer CenterNCT00338377Written as Mesna
See all 87 studies that test Mesna →
Given in every arm · 71 — Mesna is usual care beside what is tested
- CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF)RecruitingPhase 1CERo Therapeutics Holdings, Inc.NCT06834282Written as Mesna
- The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell TransplantationRecruitingPhase 1/2National Cancer Institute (NCI)NCT05436418Written as Mesna
- Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic MalignanciesRecruitingPhase 1/2National Cancer Institute (NCI)NCT04959175Written as Mesna
- A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCTRecruitingPhase 2Children's Oncology GroupNCT04684368Written as Mesna
- High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With SplenomegalyRecruitingPhase 2M.D. Anderson Cancer CenterNCT06345495Written as Mesna
- Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post ConsolidationRecruitingEarly Phase 1C17 CouncilNCT06942039Written as Mesna
- TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic MalignanciesRecruitingPhase 1St. Jude Children's Research HospitalNCT07052370Written as Mesna
- B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)RecruitingPhase 1St. Jude Children's Research HospitalNCT04897321Written as MESNA
- Autologous Stem Cell Transplantation for Crohn's DiseaseRecruitingPhase 1/2Paul SzabolcsNCT00692939Written as Mesna
- IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic CancersRecruitingPhase 1/2Indapta Therapeutics, INC.NCT06119685Written as Mesna
- Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic MelanomaActive, not recruitingPhase 1M.D. Anderson Cancer CenterNCT05470283Written as Mesna
- TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic MalignanciesActive, not recruitingPhase 2St. Jude Children's Research HospitalNCT03849651Written as Mesna
- Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue SarcomaTerminatedPhase 1Washington University School of MedicineNCT05813327Written as Mesna
- HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD ProphylaxisActive, not recruitingPhase 2Center for International Blood and Marrow Transplant ResearchNCT06001385Written as Mesna
- Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic LeukemiaActive, not recruitingPhase 1/2St. Jude Children's Research HospitalNCT03573700Written as Mesna
- Paclitaxel, Ifosfamide and Cisplatin (TIP) Versus Bleomycin, Etoposide and Cisplatin (BEP) for Patients With Previously Untreated Intermediate- and Poor-risk Germ Cell TumorsActive, not recruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT01873326Written as Mesna
- Siplizumab for Sickle Cell Disease TransplantTerminatedPhase 1/2Columbia UniversityNCT06078696Written as Mesna
- A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With Fludarabine and Melphalan Reduced Intensity Conditioning in Adults With Acute Lymphoblastic Leukaemia (ALL) in Complete Remission. (ALL-RIC)Active, not recruitingPhase 2University of BirminghamNCT03821610Written as Mesna
- Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing SarcomaActive, not recruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT01864109Written as Mesna
- HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation CyclophosphamideActive, not recruitingPhase 2Center for International Blood and Marrow Transplant ResearchNCT04904588Written as Mesna
Showing 20 of 71.
Codes
What other systems call Mesna · ClinicalTrials.gg INT008435
- MeSH (NLM) D015080MesnaConfirmed NLM, Wikidata
- UNII (FDA) NR7O1405Q9MESNAConfirmed FDA, NLM, Wikidata
- RxNorm 44Confirmed FDA, Wikidata
- Wikidata Q424997mesnaConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C192MesnaConfirmed FDA, Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D015080 | Mesna | Confirmed NLM, Wikidata |
| UNII (FDA) | NR7O1405Q9 | MESNA | Confirmed FDA, NLM, Wikidata |
| RxNorm | 44 | — | Confirmed FDA, Wikidata |
| Wikidata | Q424997 | mesna | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C192 | Mesna | Confirmed FDA, Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.