Drug
Lopinavir clinical trials
- studies test it
- 41
- open now
- 1
- in phase 3
- 10
- first study started
- 1999
Keep track of what changes. Save the Lopinavir studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Studies by the year they started
39 studies that test it; most in 2008 (8)
| Year | Studies |
|---|---|
| 1999 | 1 |
| 2001 | 1 |
| 2002 | 1 |
| 2003 | 1 |
| 2004 | 4 |
| 2005 | 3 |
| 2006 | 1 |
| 2007 | 2 |
| 2008 | 8 |
| 2009 | 5 |
| 2010 | 4 |
| 2012 | 1 |
| 2015 | 1 |
| 2016 | 3 |
| 2020 | 3 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 4
- Phase 2
- 7
- Phase 3
- 10
- Phase 4
- 16
- No phase
- 4
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 8 · Other 33
The HIV Netherlands Australia Thailand Research Collaboration (4) · Bristol-Myers Squibb (3) · GlaxoSmithKline (2) · Juan A. Arnaiz (2) · Boehringer Ingelheim (1) · Columbia University (1) · Allina Health System (1) · Willem Daniel Francois Venter (1)
Often tested with
Tested in the same studies.
Ritonavir (36) · Tenofovir (7) · Efavirenz (7) · Zidovudine (5) · Lamivudine (5) · Emtricitabine (5) · Atazanavir (4) · Saquinavir (3)
Studies
Open first, then newest update. How each study uses Lopinavir is read from its arms, and is right about nine times in ten.
Testing it · 41
- Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired PneumoniaRecruitingPhase 3UMC UtrechtNCT02735707Written as Hydroxychloroquine + lopinavir/ritonavir
- Dual Boosted - Protease Inhibitor (PI) Pharmacokinetics (PK) Trial (Tipranavir / Ritonavir) in Highly Treatment-experienced HIV-1 Infected PatientsCompletedPhase 2Boehringer IngelheimNCT00056641Written as lopinavir
- Immune Reconstitution of Lopinavir/Ritonavir-Based vs Efavirenz-based HAART in Advanced HIV DiseaseTerminatedPhase 4Rush University Medical CenterNCT00775606Written as Lopinavir 400 mg/ritonavir 100 mg
- Lopinavir and Ritonavir in Improving Immune Response to Vaccines in Patients With Complete Remission Following A Bone Marrow Transplant for Hodgkin LymphomaWithdrawnNot applicableMayo ClinicNCT01165645Written as lopinavir
- OUTpatient Treatment of COVID-19 in Patients With Risk Factor for Poor OutcomeWithdrawnPhase 3Fondation Hôpital Saint-JosephNCT04365582Written as Lopinavir 200Mg/Ritonavir 50Mg Tab
- A Study of Combination Therapies to Treat COVID-19 InfectionWithdrawnPhase 2ProgenaBiomeNCT04459702Written as Lopinavir
- Hydroxychloroquine and Lopinavir/ Ritonavir to Improve the Health of People With COVID-19: "The Hope Coalition - 1"Status unknownPhase 3CardresearchNCT04403100Written as Hydroxychloroquine Sulfate Tablets plus Lopinavir/ Ritonavir Oral Tablets
- Kaletra and Maraviroc in Antiretroviral Therapy (ART)-Naive Patients (KALMAR Study)TerminatedPhase 4Temple UniversityNCT01068873Written as lopinavir/ritonavir plus maraviroc
- Latency and Early Neonatal Provision of Antiretroviral Drugs Clinical TrialCompletedPhase 4Columbia UniversityNCT02431975Written as LPV/r
- Second-line Therapy Antiretroviral in Patients Who Failed Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI) - Based RegimensCompletedPhase 4The HIV Netherlands Australia Thailand Research CollaborationNCT00627055Written as LPV/r
- Pharmacokinetics (PK) and Safety of 2 Different Doses of Lopinavir/Ritonavir in in HIV/Tuberculosis (TB) Co-infected Patients Receiving Rifampicin Containing Anti-tuberculosis TherapyCompletedPhase 2The HIV Netherlands Australia Thailand Research CollaborationNCT01138202Written as LPV/r
- Pharmacokinetic Study of Super-boosted Lopinavir/Ritonavir Given With RifampinTerminatedPhase 4University of MiamiNCT01700790Written as Lopinavir/ritonavir and ritonavir
- Raltegravir Kaletra PharmacokineticsCompletedPhase 4Allina Health SystemNCT00564772Written as Raltegravir, lopinavir, ritonavir
- Evaluation of Low-dose Darunavir in a Switch StudyCompletedPhase 3Willem Daniel Francois VenterNCT02671383Written as Lopinavir
- Interventions for HIV Negative Men and Women Who Have High-risk Suspected Exposure to HIVCompletedPhase 2University of California, Los AngelesNCT00949234Written as tenofovir + emtricitabine, lopinavir/ritonavir
- Drug Interaction Study Between Eltrombopag and Lopinavir/Ritonavir in Healthy Adult Subjects.CompletedPhase 1GlaxoSmithKlineNCT00833378Written as Eltrombopag and Lopinavir/Ritonavir
- Evaluation of Three Strategies of Second-line Antiretroviral Treatment in Africa (Dakar - Bobo-Dioulasso - Yaoundé)CompletedPhase 3ANRS, Emerging Infectious DiseasesNCT00928187Written as emtricitabine/tenofovir + lopinavir/ritonavir (WHO recommended second line)
- Raltegravir + Lopinavir/Ritonavir or Emtricitabine/Tenofovir for HIV Treatment Naive SubjectsCompletedPhase 2Margaret A. Fischl, M.D.NCT00654147Written as Raltegravir & Lopinavir/ritonavir
- Clinical Study of an Aluvia-based HAART Regimen for Prevention of Mother-to-child HIV Transmission in AfricaCompletedPhase 4University of ZambiaNCT01088516Written as Lopinavir/Ritonavir (200/50 mg) Tablets + Zidovudine + 3TC
- Pilot Assessment of Lopinavir/Ritonavir and MaravirocTerminatedPhase 4Rodwick, Barry M., M.D.NCT00981318Written as lopinavir/ritonavir plus maraviroc
See all 41 studies that test Lopinavir →
Given in every arm · 7 — Lopinavir is usual care beside what is tested
- Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIVActive, not recruitingPhase 2/3Gilead SciencesNCT02016924Written as LPV/r
- Low Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19Status unknownNot applicableGrupo de Investigación Clínica en Oncología RadioterapiaNCT04380818Written as Ritonavir/lopinavir
- Effects of Intensive cART During Acute/Early HIV InfectionCompletedPhase 2/3University of TorontoNCT01154673Written as lopinavir 400 mg/ritonavir 100mg
- PK TDF in Thai HIV-infected ChildrenCompletedNot applicableThe HIV Netherlands Australia Thailand Research CollaborationNCT02404259Written as lopinavir/ritonavir, atazanavir/ritonavir
- Lopinavir/Ritonavir Monotherapy Versus Standard Highly Active Antiretroviral Therapy (HAART) in HIV/HCV Coinfected Antiretroviral (ARV) Naive Patients Starting Treatment With Anti-HCV TherapyStatus unknownPhase 3IRCCS San RaffaeleNCT00437476Written as LPV/r
- Lopinavir/Ritonavir Monotherapy Versus Standard Highly Active Antiretroviral Therapy (HAART) in HIV/HCV Coinfected Patients Starting Treatment With Anti-Hepatitis C Virus (HCV) TherapyStatus unknownPhase 3IRCCS San RaffaeleNCT00437684Written as LPV/r
- Efficacy of Simplified Two Drug Kaletra Regimen vs. Kaletra Triple Drug Standard of Care Regimen in Treatment naïve HIV Infected PatientsCompletedPhase 3AbbottNCT00234910Written as lopinavir/ritonavir with 2 Nucleoside RTIs
As the comparator · 3 — what is tested is compared with Lopinavir
- Evaluation of Renal Function, Efficacy, and Safety When Switching From Tenofovir/Emtricitabine Plus a Protease Inhibitor/Ritonavir, to a Combination of Raltegravir (MK-0518) Plus Nevirapine Plus Lamivudine in HIV-1 Participants With Suppressed Viremia and Impaired Renal Function (MK-0518-284)TerminatedPhase 2Merck Sharp & Dohme LLCNCT02116660Written as Lopinavir
- Study on the Impact of Triptolide Woldifiion on HIV-1 Reservoir In Acute HIV-1 InfectionStatus unknownPhase 3Peking Union Medical CollegeNCT02219672Written as Tenofovir plus lamivudine plus Lopinavir / ritonavir plus raltegravir
- A Multicentre Trial of Second-line Antiretroviral Treatment Strategies in African Adults Using Atazanavir or Lopinavir/RitonavirWithdrawnPhase 3ANRS, Emerging Infectious DiseasesNCT01255371Written as Lopinavir
Codes
What other systems call Lopinavir · ClinicalTrials.gg INT008952
- MeSH (NLM) D061466LopinavirConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 2494G1JF75LOPINAVIRConfirmed FDA, NLM, Wikidata
- RxNorm 195088Confirmed FDA, Wikidata
- Wikidata Q422585lopinavirConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C2095LopinavirOne source FDA
- DrugBank DB01601One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D061466 | Lopinavir | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 2494G1JF75 | LOPINAVIR | Confirmed FDA, NLM, Wikidata |
| RxNorm | 195088 | — | Confirmed FDA, Wikidata |
| Wikidata | Q422585 | lopinavir | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C2095 | Lopinavir | One source FDA |
| DrugBank | DB01601 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.