Drug
Saquinavir clinical trials
Also written Invirase.
- studies test it
- 41
- open now
- 0
- in phase 3
- 12
- first study started
- 1999
How studies write it
Studies that test it under each name
Name
Brand
Studies by the year they started
18 studies that test it; most in 2001 (3)
| Year | Studies |
|---|---|
| 1999 | 2 |
| 2001 | 3 |
| 2002 | 2 |
| 2003 | 1 |
| 2004 | 2 |
| 2005 | 3 |
| 2006 | 3 |
| 2008 | 1 |
| 2013 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 8
- Phase 2
- 17
- Phase 3
- 12
- Phase 4
- 6
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 21 · Other 20
Hoffmann-La Roche (16) · National Institute of Allergy and Infectious Diseases (NIAID) (7) · The HIV Netherlands Australia Thailand Research Collaboration (4) · Abbott (3) · Germans Trias i Pujol Hospital (2) · French National Agency for Research on AIDS and Viral Hepatitis (1) · Boehringer Ingelheim (1) · Radboud University Medical Center (1)
Often tested with
Tested in the same studies.
Ritonavir (16) · Nelfinavir (7) · Zidovudine (5) · Lopinavir-ritonavir drug combination (4) · Lamivudine (4) · Efavirenz (4) · Amprenavir (3) · Lopinavir (3)
Studies
Open first, then newest update. How each study uses Saquinavir is read from its arms, and is right about nine times in ten.
Testing it · 41
- Dual Boosted Protease Inhibitor Regimens Without Any Additional Antiretroviral Therapy in HIV-1 Infected Patients (ANRS127)CompletedPhase 2French National Agency for Research on AIDS and Viral HepatitisNCT00122603Written as Saquinavir
- Dual Boosted - Protease Inhibitor (PI) Pharmacokinetics (PK) Trial (Tipranavir / Ritonavir) in Highly Treatment-experienced HIV-1 Infected PatientsCompletedPhase 2Boehringer IngelheimNCT00056641Written as saquinavir
- The Anti-HIV Effects of Saquinavir Soft Gelatin Capsules Versus Indinavir in Patients Who Have Used Saquinavir Hard Gelatin Capsules for One YearCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00000848Written as Saquinavir
- A Study of Several Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Used IndinavirCompletedNot applicableNational Institute of Allergy and Infectious Diseases (NIAID)NCT00000892Written as Saquinavir
- Safety of Saquinavir and High Doses of Lopinavir/Ritonavir in Children With HIVCompletedPhase 1/2National Institute of Allergy and Infectious Diseases (NIAID)NCT00084058Written as Saquinavir
- Fortovase (Saquinavir) Given With Low-Dose Ritonavir, Zidovudine, and Lamivudine to HIV-Positive Pregnant Women During and After Pregnancy and to Their NewbornsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT00000920Written as Saquinavir
- A Study to Compare Two Anti-HIV Combination Therapies Each Containing Saquinavir in HIV-Positive ChildrenCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00000913Written as Saquinavir
- The Effects of Staggered Dosing on Interactions Between Paired Combinations of Nelfinavir, Ritonavir, and SaquinavirCompletedNot applicableNational Institute of Allergy and Infectious Diseases (NIAID)NCT00000898Written as Saquinavir
- The Pharmacokinetic Study of Saquinavir New Tablet Formulation in HIV-infected Pregnant Women.CompletedPhase 1/2Radboud University Medical CenterNCT00145561Written as Saquinavir and Ritonavir
- Study to Determine the Pharmacokinetic Behavior of Antiretroviral Drugs in Patients Infected by HIVCompletedPhase 1Germans Trias i Pujol HospitalNCT00307502Written as Saquinavir/ritonavir
- Saquinavir/Ritonavir in Single Therapy as Maintenance TreatmentCompletedPhase 4Germans Trias i Pujol HospitalNCT00379405Written as Saquinavir/Ritonavir : 2 capsules (500 mg) / 12 hours
- Influence of the MDR1 Genotype on Blood Levels of Indinavir and Saquinavir in Healthy VolunteersCompletedPhase 4National Institutes of Health Clinical Center (CC)NCT00050180Written as Saquinavir
- Efficacy and Safety of SQV in Patients Who Have Chronic IDV NephrotoxicityCompletedPhase 2The HIV Netherlands Australia Thailand Research CollaborationNCT00477048Written as Saquinavir
- Pharmacokinetic and Efficacy of SQV/r 1500/100 Plus Tenofovir/Emtricitabine 300/200 mgWithdrawnPhase 2/3The HIV Netherlands Australia Thailand Research CollaborationNCT00476983Written as saquinavir/ritonavir plus truvada
- A Comparison of Nelfinavir Plus Saquinavir Plus Delavirdine or 3TC/ZDV Versus Nelfinavir Plus 3TC/ZDV in HIV-Infected PatientsWithdrawnPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00001094Written as Saquinavir
- Testing of HIV Protease Inhibitors to Suppress Inflammation and Improve Cardio Pulmonary Hemodynamics in Subjects With Pulmonary Arterial HypertensionStatus unknownEarly Phase 1The Third Xiangya Hospital of Central South UniversityNCT02023450Written as saquinavir and ritonavir
- The Pharmacokinetics of Double Boosted Protease Inhibitors in Antiretroviral-naive HIV-1 Infected PatientsCompletedPhase 2The HIV Netherlands Australia Thailand Research CollaborationNCT00400738Written as Saquinavir, lopinavir, ritonavir
- Pharmacokinetics of Low Dose RitonavirCompletedPhase 1/2The HIV Netherlands Australia Thailand Research CollaborationNCT00622206Written as ritonavir and saquinavir
- Lopinavir Capsules to Kaletra or Invirase TabletsCompletedPhase 4Royal Free Hampstead NHS TrustNCT00438152Written as Saquinavir (Invirase®)
- Atazanavir (BMS-232632) in Combination With Ritonavir or Saquinavir, and Lopinavir/Ritonavir, Each With Tenofovir and a Nucleoside in Subjects With HIVCompletedPhase 3Bristol-Myers SquibbNCT00035932Written as Atazanavir + saquinavir + tenofovir + nucleoside
See all 41 studies that test Saquinavir →
Given in every arm · 6 — Saquinavir is usual care beside what is tested
- Effect of an Enfuvirtide-based Anti-HIV Drug Regimen on Latent HIV Reservoirs in Treatment Naive AdultsCompletedNot applicableNational Institute of Allergy and Infectious Diseases (NIAID)NCT00051831Written as Saquinavir
- A Study of Saquinavir/Ritonavir in Liver-Impaired Patients With HIV Infection.CompletedPhase 1Hoffmann-La RocheNCT00435929Written as saquinavir [Invirase]
- A Study of Ritonavir-Boosted Invirase (Saquinavir) in Treatment-Naïve HIV-1 Infected PatientsCompletedPhase 1Hoffmann-La RocheNCT01638650Written as saquinavir [Invirase]
- A Study of Invirase (Saquinavir)/Ritonavir in HIV-Infected Infants and Children.CompletedPhase 2Hoffmann-La RocheNCT00623597Written as saquinavir [Invirase]
- GEMINI Study - A Study of Saquinavir/Ritonavir in Treatment-Naive Patients With HIV-1 InfectionCompletedPhase 3Hoffmann-La RocheNCT00105079Written as saquinavir [Invirase]
- Pharmacokinetics, Safety And Toleration Of Maraviroc Administered To Subjects With Various Degrees Of Renal Impaired And Normal Renal FunctionCompletedPhase 4ViiV HealthcareNCT00717067Written as Saquinavir
As the comparator · 1 — what is tested is compared with Saquinavir
Codes
What other systems call Saquinavir · ClinicalTrials.gg INT008667
- MeSH (NLM) D019258SaquinavirConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) L3JE09KZ2FSAQUINAVIRConfirmed FDA, NLM, Wikidata
- RxNorm 83395Confirmed FDA, Wikidata
- Wikidata Q422654saquinavirConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C29444SaquinavirOne source FDA
- DrugBank DB01232One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D019258 | Saquinavir | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | L3JE09KZ2F | SAQUINAVIR | Confirmed FDA, NLM, Wikidata |
| RxNorm | 83395 | — | Confirmed FDA, Wikidata |
| Wikidata | Q422654 | saquinavir | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C29444 | Saquinavir | One source FDA |
| DrugBank | DB01232 | — | One source Wikidata |
Also registered as saquinavir mesylate (UNII UHB9Z3841A · RxNorm 859857).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.