Community-Acquired Pneumonia clinical trials

The registry lists 324 studies for Community-Acquired Pneumonia across more than 10 countries. 77 are recruiting or about to start. 259 of them are mainly about Community-Acquired Pneumonia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.

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Status

Completed: 154
Status unknown: 45
Recruiting: 41
Not yet recruiting: 34
Terminated: 24
Withdrawn: 16

Phase

Phase 3: 55
Phase 4: 35
Phase 2: 29
Phase 1: 8
Early Phase 1: 3

Where

United States: 52
France: 40
Spain: 32
China: 29
Germany: 23
Italy: 17

Who runs them

Pfizer (13) · Capital Medical University (6) · Assistance Publique - Hôpitaux de Paris (6) · Assiut University (6) · Qingyuan Zhan (6) · Hellenic Institute for the Study of Sepsis (5) · UMC Utrecht (5) · Bayer (5)

What is being tested here

Drugs under test in Community-Acquired Pneumonia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Amoxicillin	5	2	12
Methylprednisolone	5	4	8
Azithromycin	2	3	6
Ceftriaxone	2	0	5
Interleukin 1 Receptor Antagonist Protein	2	2	3
Hydroxychloroquine	2	3	3
Tocilizumab	2	2	2
Aspirin	2	2	2
Baloxavir	2	2	2
Baricitinib	2	2	2

Drug classes tested here Corticosteroids 6 open · Beta-lactamase inhibitors 2 open

Coming up

18phase 3 studies under way

22studies finish main data collection within a year6 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Dec 2026Targeting Vascular INflammation in Patients With Community-Acquired Pneumonia · Phase 3 · Ottawa Heart Institute Research Corporation
May 2027Customized Antibiotic Treatment Duration Among Hospitalized Patients With Moderately Severe Community-Acquired Pneumonia · Phase 3 · Assistance Publique - Hôpitaux de Paris
May 2027Amoxicillin Alone Versus Amoxicillin/Clavulanate for Community-acquired Pneumonia in Patients Aged 65 Years or Older, and Hospitalized in a Non-intensive Care Unit Ward · Phase 3 · Nantes University Hospital
Jun 2027Twice Daily Treatment With Amoxicillin for Non-severe Community Acquired Pneumonia. · Phase 3 · St. Justine's Hospital
Jun 2027Adaptive RCT of Corticosteroids for Severe Adenovirus Pneumonia in Adults · Phase 3 · Qingyuan Zhan
Jun 2027Corticosteroids for PJP in Non-HIV Immunocompromised Adults · Phase 3 · Qingyuan Zhan
Nov 2026Noninvasive Support Methods for Acute Respiratory Failure of Community-acquired Pneumonia · Assiut University
Nov 2026A Study to Learn How Effective is PCV20 to Help Stop Adults Who Have a Higher Chance of Getting Pneumonia · Pfizer
Nov 2026ESCAPE10: Epidemiology, Risk Factors, and Outcomes of Severe Community-acquired Pneumonia in Elderly Patients Acquired Pneumonia in Elderly Patients · Joan Sabater-Riera
Dec 2026Clinical Impact of Rapid Molecular Testing for Pathogens in Patients With Severe Acute Respiratory Illness : A Pragmatic Trial · National Taiwan University Clinical Trial Center

Who these studies take

Of the 41 Community-Acquired Pneumonia studies recruiting now, 29 (71%) set no upper age limit and 9 (22%) stop at 75 or younger. 13 (32%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (12%) take healthy volunteers.

Recruiting studies that take each age, of 41
Age	Women	Men
10	11 (27%)	11 (27%)
18	36 (88%)	36 (88%)
30	30 (73%)	30 (73%)
40	30 (73%)	30 (73%)
50	30 (73%)	30 (73%)
65	33 (80%)	33 (80%)
75	32 (78%)	32 (78%)
85	32 (78%)	32 (78%)

Across all 324 studies, recruiting or not: 23% stop at 75 or younger and 19% at 65; 25% take children; 0% are for women only and 0% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Community-Acquired Pneumonia studies take

Of 43 interventional studies with no phase under Community-Acquired Pneumonia, half reached primary completion within 24 months of starting, counting those still running.

Start to primary completion	Every sponsor	Industry	Non-industry
Interventional, no phase	24 mo14–38 · 43 studies	—	24 mo15–38 · 42 studies
Observational	31 mo22–57 · 38 studies	—	—

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Stopped1

Community-Acquired Pneumonia Diagnosis Using Lung Ultrasound in Emergency Room AdultsTerminatedNov 4, 2026NCT04210102

Newly registered2

Multimodal Stewardship Programme to Improve Antibiotic Prescribing for Children With Lower Respiratory Tract InfectionsOct 26, 2026NCT07893834
Chest Radiography Versus Ultra-Low-Dose Chest Computed Tomography in Adults in the Emergency DepartmentOct 13, 2026NCT07870525

Studies

Recruiting first, then most recently updated. Showing 50 of 324. Browse all 324 → or search them.