Hodgkin Disease clinical trials
The registry lists 1,383 studies for Hodgkin Disease across more than 10 countries. 163 are recruiting or about to start. 586 of them are mainly about Hodgkin Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
ClinicalTrials.gov finds 7,164 studies for Hodgkin Disease. How that becomes 1,383 here
This page counts the studies the registry files under Hodgkin Disease, and those it files under no condition that list Hodgkin Diseasethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 7,164Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −71List Hodgkin Disease as a condition, but the registry did not file them under itMost often written as “Classical Hodgkin Lymphoma” (18), “Recurrent/Refractory Childhood Hodgkin Lymphoma” (14), and “Classic Hodgkin Lymphoma” (6). The registry filed them under other conditions only, most often Recurrence (26) and Lymphoma, Large B-Cell, Diffuse (18).
- −5,713Match it another way29 name it in the title, 46 in a keyword, and 5,638 by a synonym or other text the search reads.
- 1,380Counted here and found by its search79 of them list Hodgkin Disease in their own words; the registry filed them under no condition.
- +3
Counted here, but its search does not find them
- HD12 for Advanced StagesNCT00265031
- HD11 for Intermediate StagesNCT00264953
- HD10 for Early StagesNCT00265018
- 1,383The count on this page
Get an email when these change. Save the Hodgkin Disease studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
National Cancer Institute (NCI) (84) · Fred Hutchinson Cancer Center (60) · M.D. Anderson Cancer Center (52) · Memorial Sloan Kettering Cancer Center (48) · City of Hope Medical Center (38) · University of Cologne (30) · St. Jude Children's Research Hospital (27) · Baylor College of Medicine (23)
What is being tested here
Drugs under test in Hodgkin Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Nivolumab | 12 | 3 | 40 |
| Cyclophosphamide | 9 | 6 | 106 |
| Brentuximab Vedotin | 8 | 6 | 67 |
| Pembrolizumab | 8 | 2 | 22 |
| Etoposide | 5 | 5 | 54 |
| Doxorubicin | 5 | 5 | 30 |
| Dacarbazine | 5 | 6 | 26 |
| Fludarabine | 4 | 1 | 77 |
| Vinblastine | 4 | 5 | 30 |
| Tislelizumab | 4 | 0 | 5 |
Drug classes tested here Immune checkpoint inhibitors 29 open · Alkylating agents 18 open · Antimetabolites 12 open · Antibody-drug conjugates (ADCs) 9 open · Antimitotic agents 6 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1) · Phase 3 · State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
- Nov 2026Communication Skills Intervention to Promote Transition Into Survivorship · Memorial Sloan Kettering Cancer Center
- Nov 2026Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma · Veronika Bachanova
- Nov 2026A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent & Young Adults With Hodgkin or Non-Hodgkin Lymphoma. · Murdoch Childrens Research Institute
- Nov 2026Interrupting Sedentary Time to Improve Cardiometabolic Health and Toxicity in Patients With Lymphoma Receiving Chemotherapy: The iSTAND Trial · Dana-Farber Cancer Institute
- Dec 2026Evaluating Combination of Nivolumab and Axatilimab in Patients With Relapsed/Refractory Classical Hodgkin Lymphoma · University of Utah
- Dec 2026A Phase 1 of CTX-8371 in Patients With Advanced Malignancies · Compass Therapeutics
- Dec 2026Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors · University of Wisconsin, Madison
- Dec 2026Cardiopulmonary Function and Cerebral Blood Flow in Hodgkin Lymphoma Survivors · St. Jude Children's Research Hospital
- Dec 2026The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen · Wake Forest University Health Sciences
Who these studies take
Of the 135 Hodgkin Disease studies recruiting now, 73 (54%) set no upper age limit and 50 (37%) stop at 75 or younger. 46 (34%) take children under 18. 2 (1%) are for women only and 0 (0%) for men only; 9 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 30 (22%) | 30 (22%) |
| 18 | 131 (97%) | 129 (96%) |
| 30 | 120 (89%) | 118 (87%) |
| 40 | 113 (84%) | 112 (83%) |
| 50 | 114 (84%) | 113 (84%) |
| 65 | 108 (80%) | 107 (79%) |
| 75 | 101 (75%) | 100 (74%) |
| 85 | 80 (59%) | 79 (59%) |
Across all 1,383 studies, recruiting or not: 39% stop at 75 or younger and 22% at 65; 34% take children; 1% are for women only and <1% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hodgkin Disease studies take
Of 206 phase 2 interventional studies under Hodgkin Disease, half reached primary completion within 75 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 57 mo41–79 · 91 studies | — | 60 mo41–80 · 66 studies |
| Phase 1/2 | 69 mo53–97 · 63 studies | — | 72 mo59–103 · 48 studies |
| Phase 2 | 75 mo42–111 · 206 studies | — | 80 mo48–115 · 183 studies |
| Phase 3 | 75 mo52–108 · 33 studies | — | 81 mo51–108 · 27 studies |
| Interventional, no phase | 43 mo29–128 · 52 studies | — | 43 mo29–128 · 49 studies |
| Observational | 61 mo34–149 · 65 studies | — | 63 mo31–149 · 58 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Results posted1
Studies
Recruiting first, then most recently updated. Showing 50 of 1,383. Browse all 1,383 → or search them.
- Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy ProtocolsRecruitingNCT026826671 country
- Pembrolizumab in Combination With Chemotherapy for the Treatment of Frail Hodgkin Lymphoma Patients Ineligible for Standard TreatmentRecruitingNCT07275216Phase 21 country
- A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and NivolumabRecruitingNCT05675410Phase 33 countries
- Autologous iC-Nine, CD30 CAR, and Constitutive IL7R Expressing EBVST for CD30 LymphomaNot yet recruitingNCT07729397Phase 11 country
- Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell LymphomaRecruitingNCT05272384Phase 11 country
- Patient-Reported Outcomes and Quality of Life in Adult and Pediatric Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma (NLPHL)RecruitingNCT060984301 country
- Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin LymphomaRecruitingNCT03618550Phase 21 country
- Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and LymphomaNot yet recruitingNCT07790913Phase 21 country
- A Phase 1 of CTX-8371 in Patients With Advanced MalignanciesRecruitingNCT06150664Phase 11 country
- Auto Stem Cell Transplant for Lymphoma PatientsRecruitingNCT03125642Phase 21 country
- Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer PatientsAvailableNCT05974410
- Personalized NK Cell Therapy in CBTRecruitingNCT02727803Phase 21 country
- Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin LymphomaRecruitingNCT03681561Phase 1/21 country
- Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a SolutionRecruitingNCT061318011 country
- Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic CancerRecruitingNCT011376431 country
- Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid TumorsRecruitingNCT02508038Phase 11 country
- Tissue Collection for Studies of Lymph CancerRecruitingNCT016768052 countries
- AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell DepletionRecruitingNCT04099966Phase 21 country
- A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell TransplantRecruitingNCT07020533Phase 11 country
- CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell TransplantRecruitingNCT06059391Phase 21 country
- Biology Studies of Hematologic CancersEnrolling by invitationNCT009234421 country
- ctDNA-Guided Therapy for Relapsed/Refractory Hodgkin LymphomaRecruitingNCT07021989Phase 21 country
- Wisconsin Ginseng for Decreasing Cancer Related FatigueRecruitingNCT06395441Phase 31 country
- Early Detection and Screening of Hematological Malignancies - SANGUINERecruitingNCT057357044 countries
- AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.RecruitingNCT06137144Phase 1/211 countries
- Establishing a Tumor Bank in Families With Multiple Lymphoproliferative MalignanciesRecruitingNCT001310141 country
- Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Bone Marrow or Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific AntibodiesRecruitingNCT06398457Early Phase 11 country
- Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive LymphomasRecruitingNCT06176690Phase 11 country
- CD30 CAR T Cells, Relapsed CD30 Expressing Lymphoma (RELY-30)RecruitingNCT02917083Phase 11 country
- The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding AreasRecruitingNCT07285044Phase 21 country
- MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin LymphomaRecruitingNCT06377540Phase 21 country
- Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic LeukemiaRecruitingNCT03418038Phase 21 country
- Positron Emission Tomography (PET) Imaging of Chemotherapy-Induced CardiotoxicityNot yet recruitingNCT07838649Phase 11 country
- Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin LymphomaRecruitingNCT04561206Phase 21 country
- Faecal Microbiota Transplantation After Allogeneic Stem Cell TransplantationRecruitingNCT04935684Phase 21 country
- A Phase II Trial of Mosunetuzumab, Polatuzumab, Tafasitamab, and Lenalidomide in Patients With Relapsed B-cell NHLRecruitingNCT05615636Phase 21 country
- Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO TrialNot yet recruitingNCT07576725Phase 21 country
- Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory LymphomaRecruitingNCT05798897Phase 11 country
- Proton Therapy for Mediastinal Lymphoma (PROMLY)RecruitingNCT07817641Not applicable1 country
- Study to Characterize Mismatched to Fully HLA-Matched Ossium HPC, Marrow and Living Donor Transplantation in Patients With Hematologic MalignanciesNot yet recruitingNCT07710781Not applicable
- Personalized Reduction of Chemotherapy Intensity Through ctDNA Evaluation for the Treatment of Patients With Advanced Hodgkin LymphomaRecruitingNCT06745076Phase 21 country
- Brentuximab Vedotin and Nivolumab for the Treatment of Relapsed/Refractory Classic Hodgkin Lymphoma Previously Treated With Brentuximab Vedotin or Checkpoint InhibitorsRecruitingNCT05039073Phase 21 country
- Phase1 Basket Trial Of CAR.70-Engineered IL15-Transduced With TGFBR2 Knock Out Cord Blood-Derived NK Cells For Relapsed/Refractory Lymphoid MalignanciesRecruitingNCT07444632Phase 11 country
- Cardiopulmonary Function and Cerebral Blood Flow in Hodgkin Lymphoma SurvivorsRecruitingNCT064219871 country
- Phase II Study Of Nivolumab Plus AVD In Pediatric, Adolescent, And Young Adult Patients With CHLRecruitingNCT07551583Phase 21 country
- New Approaches for the Diagnosis of Lymphoma and Multicentric Castleman DiseaseRecruitingNCT07793006Not applicable1 country
- A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent & Young Adults With Hodgkin or Non-Hodgkin Lymphoma.RecruitingNCT06383338Phase 11 country
- PET Guided Dose Reduction for InvOlved Site Radiotherapy In Early sTage Unfavourable Hodgkin LymphomaRecruitingNCT07256158Phase 31 country
- Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's LymphomaRecruitingNCT07514819Not applicable1 country
- Efficacy and Safety of Frontline Tislelizumab in Patients With de Novo Hodgkin Lymphoma Unsuitable for Standard Frontline ChemotherapyRecruitingNCT05977673Phase 21 country