Drug
Tenofovir clinical trials
Also written Viread, TDF and GSK548470.
- studies test it
- 281
- open now
- 11
- in phase 3
- 60
- first study started
- 1999
Keep track of what changes. Save the Tenofovir studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
264 studies that test it; most in 2012 (28)
| Year | Studies |
|---|---|
| 1999 | 1 |
| 2000 | 2 |
| 2001 | 4 |
| 2002 | 2 |
| 2003 | 5 |
| 2004 | 7 |
| 2005 | 8 |
| 2006 | 10 |
| 2007 | 9 |
| 2008 | 19 |
| 2009 | 15 |
| 2010 | 8 |
| 2011 | 18 |
| 2012 | 28 |
| 2013 | 6 |
| 2014 | 10 |
| 2015 | 25 |
| 2016 | 10 |
| 2017 | 14 |
| 2018 | 16 |
| 2019 | 12 |
| 2020 | 7 |
| 2021 | 8 |
| 2022 | 4 |
| 2023 | 4 |
| 2024 | 4 |
| 2025 | 4 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 53
- Phase 2
- 55
- Phase 3
- 60
- Phase 4
- 93
- No phase
- 31
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 77 · Other 204
Gilead Sciences (27) · National Institute of Allergy and Infectious Diseases (NIAID) (18) · GlaxoSmithKline (9) · CONRAD (9) · ANRS, Emerging Infectious Diseases (8) · Bristol-Myers Squibb (8) · University of North Carolina, Chapel Hill (6) · Kirby Institute (6)
Often tested with
Tested in the same studies.
Emtricitabine (79) · Lamivudine (27) · Efavirenz (21) · Ritonavir (20) · Entecavir (18) · Atazanavir (11) · Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (10) · Raltegravir (10)
Studies
Open first, then newest update. How each study uses Tenofovir is read from its arms, and is right about nine times in ten.
Testing it · 281
- Sleep Outcomes and Multidimensional Sleep Assessment - a Randomized Trial of Dolutegravir- vs Doravirine-based Antiretroviral Therapy in People Living With HIVNot yet recruitingPhase 4University of Witwatersrand, South AfricaNCT07673965Written as Tenofovir disoproxil fumarate 300mg / Lamivudine 300mg / Doravirine 100mg
- Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized StudyRecruitingPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT05652478Written as Tenofovir Disoproxil Fumarate
- Efficacy and Safety of Doravirine in the Rapid InitiationRecruitingPhase 4Fundación HuéspedNCT07357584Written as Doravirine / lamivudine/ Tenofovir Disoproxil Oral Tablet
- DORAvirine Versus DOlutegravir Based Antiretroviral Regimens in Treatment-naïve People Living With HIV-1 InfectionRecruitingPhase 3ANRS, Emerging Infectious DiseasesNCT06203132Written as Doravirine + tenofovir DF + lamivudine
- Comparative Trial Between Ainuovirine(ANV)/Lamivudine(3TC)/Tenofovir(TDF) and Efavirenz(EFV)/Lamivudine/Tenofovir RegimensNot yet recruitingPhase 4Shanghai Public Health Clinical CenterNCT07631897Written as Ainuovirine, Lamivudine and Tenofovir Disoproxil Fumarate Tablets
- Antiviral Clinical Trial for Long Covid-19RecruitingPhase 2Icahn School of Medicine at Mount SinaiNCT06511063Written as tenofovir disoproxil/emtricitabine
- Tenofovir Disoproxil Fumarate in the Treatment of Parkinson's DiseaseRecruitingPhase 1The Fourth Affiliated Hospital of Zhejiang University School of MedicineNCT06356662Written as Tenofovir Disoproxil Fumarate
- Study Evaluating the Safety, in Terms of HBV Virological Control At 96 Weeks, of 2 Antiviral Treatment Relief Strategies, in Patients Co-infected with the HIV-1 and HBV VirusesNot yet recruitingPhase 2ANRS, Emerging Infectious DiseasesNCT06338826Written as TDF - 245mg or TAF -25mg associated to 3TC - 300mg or FTC - 200mg and a NNRTI or PI/r or INSTI
- Change in Body Weight and BMI in PWH with DOR/3TC/TDF Compared with INSTIRecruitingPhase 4Instituto Mexicano del Seguro SocialNCT06602622Written as Doravirine + tenofovir DF + lamivudine
- HBsAg Seroclearance in Adults With HBV Related Liver Fibrosis After Receiving Combined Therapy of Peg-IFN and Tenofovir.RecruitingPhase 4Third Affiliated Hospital, Sun Yat-Sen UniversityNCT04640129Written as PEG-Interferon Alfa, Tenofovir Disoproxil Fumarate
- Implementing Oral (Event-driven and Daily) and Long-acting Pre-Exposure Prophylaxis in Mobile Men in Sub-Saharan AfricaNot yet recruitingPhase 3MRC/UVRI and LSHTM Uganda Research UnitNCT06133686Written as Tenofovir disoproxil fumarate/emtricitabine (TDF-FTC), cabotegravir (CAB-LA)
- Efficacy of Tenofovir Disoproxil on Mother-to-child Transmission of HBV in Tokombéré, Cameroon in Pregnant WomenActive, not recruitingPhase 4ANRS, Emerging Infectious DiseasesNCT05403047Written as Fumarate, Tenofovir Disoproxil
- Reducing Vertical Transmission of Hepatitis B in AfricaActive, not recruitingPhase 3University of Alabama at BirminghamNCT04704024Written as Tenofovir Disoproxil Fumarate
- IN-US-276-1340: Pre-Exposure Prophylaxis to Prevent HIV Acquisition in US Women: A Demonstration ProjectCompletedPhase 4Rutgers, The State University of New JerseyNCT03058835Written as tenofovir disoproxil and emtricitabine
- Immediate Initiation of Antiretroviral Therapy During "Hyperacute" HIV InfectionActive, not recruitingPhase 4University of California, San FranciscoNCT02656511Written as Emtricitabine/Tenofovir
- Clinical Trial of Gammora® Plus Antiretroviral Treatment for HIVActive, not recruitingPhase 2Federal University of São PauloNCT06799650Written as Gammora®
- Measure of Pharmacokinetic Parameters and Adherence With MEMS in Naive HIV Infected Patients Treated With Reyataz Once Daily Combined With Norvir and TruvadaCompletedPhase 2French National Agency for Research on AIDS and Viral HepatitisNCT00528060Written as Tenofovir/emtricitabine
- Pre-Exposure Prophylaxis (PrEP)- Gender Affirming Hormone Therapy (GAHT) Interactions in TGWCompletedPhase 1Johns Hopkins UniversityNCT04760691Written as Truvada alone
- The COMBAT HBV Feasibility TrialCompletedPhase 4University of North Carolina, Chapel HillNCT05705427Written as Tenofovir Disoproxil Fumarate 300 MG
- Study to Evaluate the Antiviral Efficacy, Safety and Tolerability of Tenofovir Disoproxil Fumarate Versus Placebo in Pediatric Participants With Chronic Hepatitis B InfectionActive, not recruitingPhase 3Gilead SciencesNCT01651403Written as Tenofovir DF
See all 281 studies that test Tenofovir →
Given in every arm · 86 — Tenofovir is usual care beside what is tested
- Clinical Trial of TQA3605 Tablet in Combination With Nucleos(t)Ide Analogues(NAs) Versus NAs Alone for the Treatment of Patients With Chronic Hepatitis B Virus Infection Who Have Undergone Treatment and Exhibit Low Viral Load or Poor ResponseNot yet recruitingPhase 3Chia Tai Tianqing Pharmaceutical Group Co., Ltd.NCT07797231Written as Tenofovir Disoproxil Fumarate Tablets
- Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCTRecruitingPhase 3Africa Health Research InstituteNCT06250504Written as tenofovir disoproxil and emtricitabine
- Efficacy and Safety of Pegylated Interferon Alpha-2β in Patients With Hepatitis B-related Hepatocellular Carcinoma After Radical ResectionNot yet recruitingEarly Phase 1Ningbo No.2 HospitalNCT07553767Written as TDF
- A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D VirusCompletedPhase 2Janssen Research & Development, LLCNCT04535544Written as Tenofovir disoproxil
- Inhibition of HBV Replication and Biological Reversal of Cirrhosis (F3-F4) and HCC by FlavonoidsCompletedPhase 4Trieu, Nguyen Thi, M.D.NCT07084948Written as Tenofovir
- Intensification With Enfuvirtide in Naive HIV-infected Patients (ANRS130)CompletedPhase 3French National Agency for Research on AIDS and Viral HepatitisNCT00302822Written as emtricitabine/tenofovir
- Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With MenCompletedPhase 2/3National Institute of Allergy and Infectious Diseases (NIAID)NCT02720094Written as TDF/FTC tablets
- A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B InfectionCompletedPhase 1/2Vir Biotechnology, Inc.NCT05612581Written as TDF
- Study of ARC-520 With or Without Other Drugs Used in the Treatment of Chronic Chronic Hepatitis B Virus (HBV)TerminatedPhase 2Arrowhead PharmaceuticalsNCT02577029Written as tenofovir disoproxil
- A Multi-dose Study of ARC-520 in Patients With Hepatitis B 'e' Antigen (HBeAg) Positive, Chronic Hepatitis B Virus InfectionTerminatedPhase 2Arrowhead PharmaceuticalsNCT02604212Written as tenofovir
- A Multi-dose Study of ARC-520 in Patients With Hepatitis B 'e' Antigen (HBeAg) Negative, Chronic Hepatitis B Virus (HBV) InfectionTerminatedPhase 2Arrowhead PharmaceuticalsNCT02604199Written as tenofovir
- A Study of ARC-521 Injection in Normal Adult Volunteers and Patients With Chronic Hepatitis B (CHB)TerminatedPhase 1Arrowhead PharmaceuticalsNCT02797522Written as tenofovir
- Study of ARC-520 in Participants With Hepatitis B Virus e Antigen (HBeAg) Positive Chronic Hepatitis B VirusTerminatedPhase 2Arrowhead PharmaceuticalsNCT02452528Written as Tenofovir
- Evaluating the Safety and Efficacy of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected WomenActive, not recruitingPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT03164564Written as Oral TDF/FTC
- Clinical Trial to Evaluate the Efficacy, Pharmacokinetics (PK) Interactions and Safety of Dolutegravir Plus 2 Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in HIV-1-Infected Solid Organ Transplant PatientsCompletedPhase 4Fundacion Clinic per a la Recerca BiomédicaNCT03360682Written as Tenofovir Disoproxil 245Mg Tablet
- DOT Diary Mobile App for Pre-Exposure Prophylaxis Adherence in Young MenCompletedPhase 4Public Health Foundation Enterprises, Inc.NCT03771638Written as Emtricitabine / Tenofovir Disoproxil Oral Tablet
- A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) InfectionCompletedPhase 2Janssen Research & Development, LLCNCT04439539Written as Tenofovir disoproxil
- A Study of JNJ-73763989, JNJ-64300535, and Nucleos(t)Ide Analogs in Virologically Suppressed, Hepatitis B e Antigen (HBeAg)- Negative Participants With Chronic Hepatitis B Virus InfectionCompletedPhase 1Janssen Research & Development, LLCNCT05123599Written as Tenofovir disoproxil
- A Study to Assess Intrahepatic and Peripheral Changes of Immunologic and Virologic Markers in Chronic Hepatitis B Virus InfectionCompletedPhase 2Janssen Research & Development, LLCNCT04585789Written as Tenofovir disoproxil
- Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent MalesCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT04692077Written as Tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) tablet
Showing 20 of 86.
As the comparator · 61 — what is tested is compared with Tenofovir
- Dolutegravir/Lamivudine Dual Therapy for ART-naïve People With HIV and TB Receiving Rifampin-based TB TreatmentRecruitingPhase 3Johns Hopkins UniversityNCT06497465Written as Dolutegravir plus Tenofovir disoproxil fumarate (TDF)/ lamivudine (3TC)
- TAF in Early/Middle Pregnancy With CHBEnrolling by invitationPhase 4The Third Affiliated Hospital of Guangzhou Medical UniversityNCT07668934Written as TDF
- Comparison of TAF and TDF in Preventing Mother-to-Child Transmission of HBV in Pregnancies With High Viral LoadsRecruitingNot applicableGuangzhou 8th People's HospitalNCT06947356Written as TDF group
- Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLFRecruitingNot applicableThird Affiliated Hospital, Sun Yat-Sen UniversityNCT03920618Written as Tenofovir Disoproxil Fumarate
- A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)Active, not recruitingPhase 2Aligos TherapeuticsNCT06963710Written as TDF
- Dolutegravir-Lamivudine for naïve HIV-Infected Patients With ≤200 CD4/mm3CompletedPhase 4Fundación HuéspedNCT04880395Written as Comparator ARM: TDF/XTC plus Dolutegravir (XTC stand for lamivudine OR emtricitabine)
- The ADAPT Study: Use of Emtricitabine and Tenofovir Disoproxil Fumarate for Pre-Exposure Prophylaxis (PrEP)CompletedPhase 2HIV Prevention Trials NetworkNCT01327651Written as Daily dosing
- Change of Renal Function and Bone Mineral Density in CHB Patients Switch From TDF to TAF vs. Maintaining TDFCompletedPhase 4Humanity and Health Research CentreNCT03356834Written as Tenofovir disoproxil fumarate(TDF)
- Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Positive Hepatitis B (China)CompletedPhase 3Gilead SciencesNCT02836249Written as TDF
- Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Negative Hepatitis B (China)CompletedPhase 3Gilead SciencesNCT02836236Written as TDF
- PK of TAF and TDF for PrEP in Pregnant and Postpartum WomenCompletedPhase 3University of California, Los AngelesNCT04937881Written as Tenofovir Disoproxil Fumarate
- A Study of Peginterferon Alfa-2b Combined With TDF in Patients With Chronic Hepatitis BCompletedPhase 3Xiamen Amoytop Biotech Co., Ltd.NCT04846491Written as TDF
- A Study to Determine Safety and Efficacy of Dolutegravir/Abacavir/Lamivudine (DTG/ABC/3TC) in Human Immunodeficiency Virus (HIV)-1 Infected Antiretroviral Therapy (ART) Naïve Women (ARIA)CompletedPhase 3ViiV HealthcareNCT01910402Written as Tenofovir/emtricitabine FDC
- Adjuvant Entecavir or Tenofovir for Postoperative HBV-HCCCompletedPhase 3Guangxi Medical UniversityNCT02650271Written as Tenofovir
- Open-Label Study Comparing Efficacy and Safety of ATV/RTV+3TC With ATV/RTV+TDF/FTC in HIV-Infected, Treatment Naïve Subjects, Followed by Treatment With ATV/RTV+3TCTerminatedPhase 3Bristol-Myers SquibbNCT01620944Written as Tenofovir/Emtricitabine
- An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir (DTG) Plus Lamivudine (3TC) With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Participants (Gemini 2)CompletedPhase 3ViiV HealthcareNCT02831764Written as Tenofovir disoproxil fumarate/Emtricitabine (TDF/FTC FDC)
- Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Positive for Hepatitis B e AntigenCompletedPhase 3Gilead SciencesNCT01940471Written as TDF
- Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Negative for Hepatitis B e AntigenCompletedPhase 3Gilead SciencesNCT01940341Written as TDF
- An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir Plus Lamivudine With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Subjects (Gemini 1)CompletedPhase 3ViiV HealthcareNCT02831673Written as Tenofovir disoproxil fumarate/Emtricitabine (TDF/FTC FDC)
- Finite Versus Continuous Nucleos(t)Ide Analogues for Chronic Hepatitis BActive, not recruitingNot applicableE-DA HospitalNCT05793268Written as Entecavir or Tenofovir
Showing 20 of 61.
Codes
What other systems call Tenofovir · ClinicalTrials.gg INT006531
- MeSH (NLM) D000068698TenofovirConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 99YXE507ILTENOFOVIRConfirmed FDA, NLM, Wikidata
- RxNorm 117466One source FDA
- Wikidata Q106010187tenofovir hydrateConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C29490TenofovirOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000068698 | Tenofovir | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 99YXE507IL | TENOFOVIR | Confirmed FDA, NLM, Wikidata |
| RxNorm | 117466 | — | One source FDA |
| Wikidata | Q106010187 | tenofovir hydrate | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C29490 | Tenofovir | One source FDA |
Also registered as tenofovir disoproxil (UNII F4YU4LON7I · RxNorm 300195) and tenofovir disoproxil fumarate (UNII OTT9J7900I · RxNorm 322248).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.