Spinal Dysraphism clinical trials
The registry lists 142 studies for Spinal Dysraphism across more than 10 countries. 39 are recruiting or about to start. 70 of them are mainly about Spinal Dysraphism (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its narrower condition Spina Bifida Cystica too: 145 studies, 40 open.
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Who runs them
Rennes University Hospital (7) · University of Alabama at Birmingham (4) · McGill University (4) · Holland Bloorview Kids Rehabilitation Hospital (4) · University Hospital, Clermont-Ferrand (4) · Assistance Publique - Hôpitaux de Paris (3) · Medstar Health Research Institute (3) · Baylor College of Medicine (3)
What is being tested here
Drugs under test in Spinal Dysraphism studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Grand Valley State University (GVSU) Skills on Wheels · Grand Valley State University
- Dec 2026Comparing Digitally and Traditionally Made Ankle Foot Orthoses · Holland Bloorview Kids Rehabilitation Hospital
- Dec 2026Motor Imagery-Supported Thoracic Expansion in Children With Spina Bifida · Karabuk University
- Dec 2026Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical Setting · ABLE Human Motion S.L.
- Dec 2026Evaluation of the Transitional and Lifelong Care Program · Western University, Canada
- Jan 2027Psychosocial Teleassistance Programme for Adults With Spina Bifida · University of Deusto
- Mar 2027EVALUATION OF THE SAFETY AND EFFICACY OF ADJUSTABLE CONTINENT THERAPY IN CHILDREN WITH SPINAL DYSRAPHISM. · Assistance Publique Hopitaux De Marseille
- Apr 2027Fetoscopic Repair of Isolated Fetal Spina Bifida · Johns Hopkins University
- Apr 2027Folic Acid Salt Study (FISFA Zambia) · University of Alabama at Birmingham
- Jul 2027Evaluation of muLtimodal and Non-invasive SPINa Bifida Neurovessels During Prospective Follow-up · Rennes University Hospital
Who these studies take
Of the 29 Spinal Dysraphism studies recruiting now, 12 (41%) set no upper age limit and 17 (59%) stop at 75 or younger. 20 (69%) take children under 18. 5 (17%) are for women only and 0 (0%) for men only; 3 (10%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 17 (59%) | 17 (59%) |
| 18 | 19 (66%) | 14 (48%) |
| 30 | 16 (55%) | 11 (38%) |
| 40 | 15 (52%) | 10 (34%) |
| 50 | 14 (48%) | 10 (34%) |
| 65 | 14 (48%) | 10 (34%) |
| 75 | 13 (45%) | 9 (31%) |
| 85 | 12 (41%) | 8 (28%) |
Across all 142 studies, recruiting or not: 63% stop at 75 or younger and 61% at 65; 69% take children; 16% are for women only and 1% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Spinal Dysraphism studies take
Of 62 interventional studies with no phase under Spinal Dysraphism, half reached primary completion within 31 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 31 mo20–57 · 62 studies | — | 31 mo20–57 · 60 studies |
| Observational | 29 mo8–36 · 22 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
- Parenting Program for Young Children With Spina BifidaNov 4, 2026NCT07915557
Studies
Recruiting first, then most recently updated. Showing 50 of 142. Browse all 142 → or search them.
- Transcutaneous Spinal Stimulation for Children and Youth With Spina BifidaRecruitingNCT06918119Not applicable1 country
- Parenting Program for Young Children With Spina BifidaNot yet recruitingNCT07915557Not applicable1 country
- EVALUATION OF THE SAFETY AND EFFICACY OF ADJUSTABLE CONTINENT THERAPY IN CHILDREN WITH SPINAL DYSRAPHISM.RecruitingNCT03351634Not applicable1 country
- Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement DisordersRecruitingNCT05726591Not applicable1 country
- Motor Imagery-Supported Thoracic Expansion in Children With Spina BifidaNot yet recruitingNCT07846202Not applicable1 country
- Bowel Continence Across the Lifespan in People With Spina BifidaRecruitingNCT073903181 country
- Autologous Human Umbilical Cord Tissue Patch for Postnatal Closure of Open Neural Tube DefectsRecruitingNCT06929572Not applicable1 country
- tSCS in Children With Spina BifidaRecruitingNCT07615686Not applicable1 country
- Clinical Investigation to Validate the Safety and Performance of the ABLE Kids Device in Pediatric Patients With Neurological Gait Disorders in a Clinical SettingRecruitingNCT07745712Not applicable1 country
- Enema Device for Children With Spina BifidaRecruitingNCT05253196Not applicable1 country
- Mobile Health Self-Management and Support System for Chronic and Complex Health ConditionsRecruitingNCT02592291Not applicable1 country
- Coupled Gentamicin-Lactobacillus Rhamnosus in NLUTDNot yet recruitingNCT07643974Early Phase 11 country
- Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young AdultsRecruitingNCT069981341 country
- Folic Acid Salt Study (FISFA Zambia)RecruitingNCT06734611Not applicable2 countries
- Establishing the Preliminary Utility of a Novel Pediatric Manual Mobile Standing WheelchairRecruitingNCT07290556Not applicable1 country
- Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CICRecruitingNCT05491525Phase 2/316 countries
- Adult Bladder and Quality of Life Evaluation in Spina BifidaRecruitingNCT076424661 country
- Efficacy of Intravesical Oxybutynin in Children With Neurogenic Bladder DysfunctionRecruitingNCT07027020Phase 31 country
- Evaluation of the Transitional and Lifelong Care ProgramRecruitingNCT058492851 country
- Transcutaneous Tibial Nerve Stimulation (TTNS) Treatment in Spina Bifida Pediatric Patients With Neurogenic BladderRecruitingNCT06025734Not applicable1 country
- Evaluation of muLtimodal and Non-invasive SPINa Bifida Neurovessels During Prospective Follow-upRecruitingNCT06041334Not applicable1 country
- Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair CasesRecruitingNCT05672849Not applicable1 country
- Psychosocial Teleassistance Programme for Adults With Spina BifidaRecruitingNCT07178873Not applicable1 country
- Comparing Digitally and Traditionally Made Ankle Foot OrthosesRecruitingNCT06828653Not applicable1 country
- Cryopreserved Human Umbilical Cord as a Meningeal Patch in Fetoscopic Spina Bifida RepairRecruitingNCT06042140Not applicable1 country
- Fetoscopic Neural Tube Defect RepairRecruitingNCT069465631 country
- QUALAS Validation in DutchRecruitingNCT067239511 country
- Effectiveness of Biofeedback Training in Children with Neurogenic Bladder and Bowel Disorder Wıth Spina BifidaNot yet recruitingNCT06618378Not applicable
- Impact of Standing Programs in Children With Spina Bifida: A Single Subject DesignRecruitingNCT06419049Not applicable1 country
- Uronephrological Complications Risk Factors in Spinal DysraphismRecruitingNCT057184401 country
- The Effect of Press Needle in the Combination of Ear and Body Acupuncture Points on Visual Analog Scale in Post-Operative Patients of Open Spine SurgeryRecruitingNCT06165575Not applicable1 country
- Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Non-cardiac SurgeryNot yet recruitingNCT06144099Phase 4
- Downstream Effects of Personalized 'Top-down' Participation-based Interventions Among Youth With Physical DisabilitiesNot yet recruitingNCT05784285Not applicable1 country
- Examining Capacity Building of Youth With Physical Disabilities to Pursue Participation Following the PREP Intervention.Not yet recruitingNCT06007885Not applicable1 country
- Determining Developmental and Clinical Markers Affecting Urinary Function of Children With Spinal DysraphismRecruitingNCT059620861 country
- Complications of Enterocystoplasty in ChildrenEnrolling by invitationNCT058408741 country
- The Role of Active Administration of Peristeen Bowel Evacuation for the Management of Urinary Tract InfectionEnrolling by invitationNCT04815226Not applicable1 country
- Laparotomy Versus Percutaneous Endoscopic Correction of MyelomeningoceleRecruitingNCT03856034Not applicable1 country
- Urothelium Tissue Engineering Using Biopsies From Transurethral Resection of ProstateNot yet recruitingNCT03698721
- Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement DisordersCompletedNCT01961557Not applicable1 country
- Incontinence and Quality of Life in Children With Spina BifidaCompletedNCT03410667Not applicable1 country
- The Impact of Community-based Wellness Programs on The Triple AimCompletedNCT029381301 country
- Metformin in Children With Motor DeficitCompletedNCT00720161Not applicable1 country
- Fetoscopic NEOX Cord 1K® Spina Bifida RepairActive, not recruitingNCT04243889Not applicable1 country
- A New Training to Enhance Physical Activity in Adolescents With Cerebral PalsyCompletedNCT05865418Not applicable1 country
- Assessing Transition Practices for Children With Disabilities: Pathways to a Successful AdulthoodCompletedNCT077065171 country
- Fetoscopic Meningomyelocele Repair StudyCompletedNCT02230072Phase 11 country
- Spina Bifida Healthcare Navigator ProgramActive, not recruitingNCT07531862Not applicable1 country
- In-Utero Endoscopic Correction of Spina BifidaActive, not recruitingNCT04362592Not applicable1 country
- Fetoscopic Repair of Isolated Fetal Spina BifidaActive, not recruitingNCT03090633Not applicable1 country