Drug
Floxuridine clinical trials
Also written FUDR, WR-138720 and 5-FUdR.
- studies test it
- 50
- open now
- 7
- in phase 3
- 8
- first study started
- 1994
Keep track of what changes. Save the Floxuridine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
Combined with it in one product
Studies by the year they started
49 studies that test it; most in 2000 (4); 1 more planned to start later
| Year | Studies |
|---|---|
| 1994 | 1 |
| 1995 | 1 |
| 1996 | 2 |
| 1997 | 2 |
| 1998 | 2 |
| 2000 | 4 |
| 2002 | 2 |
| 2003 | 4 |
| 2004 | 1 |
| 2005 | 3 |
| 2006 | 2 |
| 2007 | 1 |
| 2008 | 1 |
| 2011 | 1 |
| 2012 | 1 |
| 2013 | 2 |
| 2014 | 1 |
| 2015 | 2 |
| 2018 | 3 |
| 2019 | 2 |
| 2020 | 2 |
| 2021 | 4 |
| 2022 | 1 |
| 2024 | 4 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 11
- Phase 2
- 33
- Phase 3
- 8
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 50
Memorial Sloan Kettering Cancer Center (13) · National Cancer Institute (NCI) (5) · City of Hope Medical Center (3) · University of Miami (3) · NYU Langone Health (3) · Sun Yat-sen University (2) · Alliance for Clinical Trials in Oncology (2) · Oslo University Hospital (2)
Often tested with
Tested in the same studies.
Oxaliplatin (13) · Fluorouracil (11) · Dexamethasone (10) · Irinotecan (8) · Leucovorin (7) · Gemcitabine (6) · Bevacizumab (3) · Docetaxel (3)
Studies
Open first, then newest update. How each study uses Floxuridine is read from its arms, and is right about nine times in ten.
Testing it · 50
- Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With SurgeryRecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT04891289Written as Floxuridine (FUDR)
- CCR5 Targeting Leronlimab in Combination With Hepatic Arterial Infusion Floxuridine and Systemic Therapy for the Treatment of Colorectal Cancer Liver Metastases, CHAMP TrialNot yet recruitingPhase 1City of Hope Medical CenterNCT07842965Written as Floxuridine
- Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP TrialRecruitingPhase 3ECOG-ACRIN Cancer Research GroupNCT05863195Written as Floxuridine
- Hepatic Arterial Infusion Chemotherapy in Patients With Inoperable Colorectal Cancer Liver MetastasisRecruitingPhase 2Sunnybrook Health Sciences CentreNCT07764497Written as Floxuridine (FUDR)
- HAI-Floxuridine, or SIRT, Combined With Gemox For Patients With Intra-Hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT)RecruitingPhase 2Oslo University HospitalNCT06313203Written as Floxuridine
- Induction Treatment for Initially Unresectable Colorectal Liver Metastases: Combined Hepatic Arterial Infusion Pump Therapy With Systemic TherapyRecruitingPhase 3The Netherlands Cancer InstituteNCT06857773Written as Intra arterial infusion Floxuridine (FUDR) combined with systemic therapy
- Prospective Real-World Study of HAIC With Raltitrexed or 5-Fluorouracil for the Treatment of Hepatocellular CarcinomaRecruitingNot applicableRenJi HospitalNCT06519578Written as hepatic artery infusion chemotherapy
- HAI-Floxuridine, or Liver-Tx, Combined With 2nd Line Chemotherapy Versus 2nd Line Chemotherapy Alone for Patients With Colorectal Liver Metastases and Heavy Tumour Burden.TerminatedPhase 2Oslo University HospitalNCT04898504Written as Floxuridine
- Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the LiverCompletedPhase 2National Cancer Institute (NCI)NCT03366155Written as Floxuridine
- Hepatic Artery Infusional Floxuridine to Treat Pancreatic Cancer Liver MetastasesActive, not recruitingPhase 2Corewell Health WestNCT03856658Written as Floxuridine (FUDR)
- Hepatic Arterial Infusion (HAI) With Floxuridine (FUDR) and Dexamethasone (Dex) Combined With Systemic Gemcitabine and Oxaliplatin in Patients With Unresectable Intrahepatic Cholangiocarcinoma (ICC)CompletedPhase 2Memorial Sloan Kettering Cancer CenterNCT01862315Written as Floxuridine (FUDR)
- mFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic CholangiocarcinomaTerminatedPhase 2OHSU Knight Cancer InstituteNCT04251715Written as Floxuridine
- A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or CholangiocarcinomaCompletedPhase 2Memorial Sloan Kettering Cancer CenterNCT03693807Written as Floxuridine (FUDR)
- Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal CancerCompletedPhase 1Memorial Sloan Kettering Cancer CenterNCT00059930Written as floxuridine
- Floxuridine and Dexamethasone as a Hepatic Arterial Infusion and Bevacizumab in Treating Patients With Primary Liver Cancer That Cannot be Removed by SurgeryCompletedPhase 2Memorial Sloan Kettering Cancer CenterNCT00410956Written as floxuridine
- Adjuvant Systemic Chemotherapy With or Without HAI-FUDR in Patients With Resected CRLMTerminatedPhase 3Sun Yat-sen UniversityNCT03500874Written as FUDR
- A Phase II Study of Continuous Hepatic Arterial Infusion With Floxuridine (FUDR) and Dexamethasone (DEX) in Patients With Unresectable Primary Hepatic MalignancyCompletedPhase 2Memorial Sloan Kettering Cancer CenterNCT00587067Written as FLOXURIDINE
- A Study of Systemic Chemotherapy With CPT-11 Plus HAI (FUDR+L-OHP) in Patients With Initially Unresectable CRCLMCompletedPhase 2Sun Yat-sen UniversityNCT03493061Written as Floxuridine
- HAIC Combined With Sintilimab and Bevacizumab Biosimilar for Unresectable HCCStatus unknownPhase 2Tianjin Medical University Cancer Institute and HospitalNCT05029973Written as HAIC
- Sintilimab Combined With Regorafenib and HAIC in Patients With Colorectal Liver MetastasisStatus unknownPhase 2Tianjin Medical University Cancer Institute and HospitalNCT05524155Written as HAIC
See all 50 studies that test Floxuridine →
Given in every arm · 5 — Floxuridine is usual care beside what is tested
- PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical CarcinomaRecruitingPhase 2National Cancer Institute (NCI)NCT05286814Written as Floxuridine
- Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the LiverActive, not recruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT00492999Written as floxuridine
- FUDR/Oxaliplatin HAI Plus Irinotecan vs. FOLFOXIRI Chemotherapy in Treating Initially Unresectable CRCLMTerminatedPhase 3Sun Yat-sen UniversityNCT03678428Written as Floxuridine
- Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic CholangiocarcinomaTerminatedPhase 1Washington University School of MedicineNCT01525069Written as Floxuridine
- Study of Chemotherapy With or Without Hepatic Arterial Infusion for Patients With Unresectable Metastatic Colorectal Cancer to the LiverWithdrawnPhase 2Memorial Sloan Kettering Cancer CenterNCT03069950Written as Floxuridine (FUDR)
Codes
What other systems call Floxuridine · ClinicalTrials.gg INT007509
- MeSH (NLM) D005467FloxuridineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 039LU44I5MFLOXURIDINEConfirmed FDA, NLM, Wikidata
- RxNorm 4488Confirmed FDA, Wikidata
- Wikidata Q5462356floxuridineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C504FloxuridineOne source FDA
- DrugBank DB00322One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D005467 | Floxuridine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 039LU44I5M | FLOXURIDINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 4488 | — | Confirmed FDA, Wikidata |
| Wikidata | Q5462356 | floxuridine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C504 | Floxuridine | One source FDA |
| DrugBank | DB00322 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.