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Cholangiocarcinoma clinical trials

The registry lists 824 studies for Cholangiocarcinoma across more than 10 countries. 287 are recruiting or about to start. 450 of them are mainly about Cholangiocarcinoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its narrower condition Klatskin Tumor too: 871 studies, 299 open.

ClinicalTrials.gov finds 1,101 studies for Cholangiocarcinoma. How that becomes 824 here

This page counts the studies the registry files under Cholangiocarcinoma, and those it files under no condition that list Cholangiocarcinomathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 1,101Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −47Filed under a narrower condition, counted on its own pageKlatskin Tumor 45
  3. −42List Cholangiocarcinoma as a condition, but the registry did not file them under itMost often written as “Cholangiocarcinoma of the Extrahepatic Bile Duct” (14), “Cholangiocarcinoma of the Gallbladder” (9), and “Adult Primary Cholangiocellular Carcinoma” (6). The registry filed them under other conditions only, most often Gallbladder Neoplasms (16) and Pancreatic Neoplasms (14).
  4. −188Match it another way32 name it in the title, 19 in a keyword, and 137 by a synonym or other text the search reads.
  5. 824The count on this page44 of them list Cholangiocarcinoma in their own words; the registry filed them under no condition.

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Status

Completed
232
Recruiting
211
Terminated
103
Status unknown
95
Not yet recruiting
66
Active, not recruiting
66

Phase

Phase 2
364
Phase 1
174
Phase 3
58
Phase 4
8
Early Phase 1
7

Where

United States
327
China
229
France
74
Korea, Republic of
68
Germany
62
Italy
57

Who runs them

National Cancer Institute (NCI) (23) · Fudan University (17) · Shanghai Zhongshan Hospital (16) · Mayo Clinic (15) · M.D. Anderson Cancer Center (12) · Tianjin Medical University Cancer Institute and Hospital (11) · Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest (9) · Weill Medical College of Cornell University (9)

What is being tested here

Drugs under test in Cholangiocarcinoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Lenvatinib17330
Durvalumab14020
Gemcitabine10649
Cisplatin9527
Tislelizumab7013
Adebrelimab707
Pemigatinib5112
Apatinib409
Fluorouracil3313
Pembrolizumab3412

Drug classes tested here Immune checkpoint inhibitors 49 open · Tyrosine kinase inhibitors (TKIs) 40 open · Antimetabolites 18 open · Antimitotic agents 2 open · Angiogenesis inhibitors 1 open

Coming up

27phase 3 studies under way
82studies finish main data collection within a year7 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 211 Cholangiocarcinoma studies recruiting now, 141 (67%) set no upper age limit and 49 (23%) stop at 75 or younger. 10 (5%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 14 (7%) take healthy volunteers.

Recruiting studies that take each age, of 211
AgeWomenMen
108 (4%)8 (4%)
18200 (95%)200 (95%)
30209 (99%)209 (99%)
40211 (100%)211 (100%)
50211 (100%)211 (100%)
65211 (100%)211 (100%)
75201 (95%)201 (95%)
85154 (73%)154 (73%)

Across all 824 studies, recruiting or not: 17% stop at 75 or younger and 1% at 65; 5% take children; 0% are for women only and 0% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Cholangiocarcinoma studies take

Of 173 phase 2 interventional studies under Cholangiocarcinoma, half reached primary completion within 46 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 146 mo30–63 · 67 studies41 mo28–60 · 44 studies—
Phase 1/268 mo41–77 · 40 studies——
Phase 246 mo29–65 · 173 studies—46 mo30–65 · 147 studies
Interventional, no phase43 mo28–… · 67 studies—43 mo28–… · 66 studies
Observational60 mo33–… · 70 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 14, 2026.

Started recruiting2

Results posted1

Stopped1

Newly registered3

Studies

Recruiting first, then most recently updated. Showing 50 of 824. Browse all 824 → or search them.