Spondylitis, Ankylosing clinical trials
The registry lists 531 studies for Spondylitis, Ankylosing across more than 10 countries. 98 are recruiting or about to start. 360 of them are mainly about Spondylitis, Ankylosing (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
ClinicalTrials.gov finds 557 studies for Spondylitis, Ankylosing. How that becomes 531 here
This page counts the studies the registry files under Spondylitis, Ankylosing, and those it files under no condition that list Spondylitis, Ankylosingthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 557Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −6List Spondylitis, Ankylosing as a condition, but the registry did not file them under itMost often written as “Spondylarthropathies; Spondylitis, Ankylosing” (2), “Juvenile Ankylosing Spondylitis” (1), and “Active Ankylosing Spondylitis or Non-Radiographic Axial Spondyloarthritis” (1). The registry filed them under other conditions only, most often Spondylitis (3) and Spondylarthropathies (2).
- −20Match it another way17 name it in the title, 1 in a keyword, and 2 by a synonym or other text the search reads.
- 531The count on this page9 of them list Spondylitis, Ankylosing in their own words; the registry filed them under no condition.
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Status
Who runs them
Pfizer (20) · Novartis Pharmaceuticals (19) · AbbVie (15) · Wyeth is now a wholly owned subsidiary of Pfizer (14) · Merck Sharp & Dohme LLC (13) · Charite University, Berlin, Germany (13) · AbbVie (prior sponsor, Abbott) (10) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (8)
What is being tested here
Drugs under test in Spondylitis, Ankylosing studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Secukinumab | 3 | 11 | 20 |
| Etanercept | 2 | 7 | 27 |
| Adalimumab | 2 | 8 | 19 |
| Infliximab | 1 | 6 | 20 |
| Golimumab | 1 | 4 | 10 |
| Certolizumab Pegol | 1 | 2 | 7 |
| Bimekizumab | 1 | 2 | 6 |
| Celecoxib | 1 | 2 | 6 |
| Methotrexate | 1 | 1 | 5 |
| Ixekizumab | 1 | 4 | 5 |
Drug classes tested here JAK inhibitors 3 open · Tyrosine kinase inhibitors (TKIs) 3 open · NSAIDs 1 open · COX-2 inhibitors 1 open · Antimetabolites 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026A Study to Evaluate Efficacy and Safety of LNK01001 in Adults With Ankylosing Spondylitis · Phase 3 · Lynk Pharmaceuticals Co., Ltd
- Dec 2026A Study of Comparing Overall Improvement of Patients With Spondyloarthritis Treated With Jitongning Tablets and Placebo · Phase 3 · Tasly Pharmaceutical Group Co., Ltd
- Jan 2027A Study to Evaluate the Efficacy and Safety of 608 in Adult Subjects With Active Ankylosing Spondylitis(AS) · Phase 3 · Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
- Aug 2027Efficacy and Safety Phase III Clinical Study of VC005 Tablets in Subjects With Active Ankylosing Spondylitis. · Phase 3 · Jiangsu vcare pharmaceutical technology co., LTD
- Nov 2026An Investigation of the Effect of Smartphone Usage Levels on Cervical Posture, Tongue Pressure, Balance, and Neck Disability in Individuals With Rheumatoid Arthritis and Ankylosing Spondylitis · Merve Şahin
- Nov 2026Evaluation of Serum IL-41 Level in Patients With Ankylosing Spondylitis and Psoriatic Arthritis · Assiut University
- Nov 2026Deep Breathing Combined With Core Stability Exercises in the Treatment of Patients With Ankylosing Spondylitis · Beni-Suef University
- Dec 2026Ankylosing Spondylitis · Sohag University
- Dec 2026Safety and Tolerance of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in Patients With Ankylosing Spondylitis · Asia Cell Therapeutics (Shanghai) Co., Ltd.
- Dec 2026A Study of HB0017 Injection in Healthy Volunteers to Evaluate Safety and Tolerability of a Single Subcutaneous Injection in Low-Body-Weight Subjects; and Pharmacokinetics at Different Subcutaneous Injection Sites at the Same Dose · Huabo Biopharm Co., Ltd.
Who these studies take
Of the 63 Spondylitis, Ankylosing studies recruiting now, 25 (40%) set no upper age limit and 32 (51%) stop at 75 or younger. 10 (16%) take children under 18. 0 (0%) are for women only and 1 (2%) for men only; 15 (24%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 7 (11%) | 7 (11%) |
| 18 | 57 (90%) | 58 (92%) |
| 30 | 62 (98%) | 63 (100%) |
| 40 | 62 (98%) | 63 (100%) |
| 50 | 60 (95%) | 61 (97%) |
| 65 | 53 (84%) | 54 (86%) |
| 75 | 35 (56%) | 35 (56%) |
| 85 | 30 (48%) | 30 (48%) |
Across all 531 studies, recruiting or not: 42% stop at 75 or younger and 29% at 65; 9% take children; 1% are for women only and 1% for men only; 16% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Spondylitis, Ankylosing studies take
Of 40 phase 3 interventional studies under Spondylitis, Ankylosing, half reached primary completion within 21 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 15 mo12–31 · 22 studies | — | — |
| Phase 3 | 21 mo15–32 · 40 studies | 21 mo15–28 · 38 studies | — |
| Phase 4 | 32 mo25–36 · 18 studies | — | — |
| Interventional, no phase | 12 mo7–20 · 64 studies | — | 12 mo7–20 · 61 studies |
| Observational | 47 mo30–116 · 78 studies | 44 mo33–73 · 33 studies | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
- Pain Phenotyping of Rheumatic Diseases - An Observational StudyNov 3, 2026NCT07829497
- Phase Ia Study of MST-931 in Healthy Adult SubjectsNov 3, 2026NCT07903493
Newly registered7
- A Study of HB0017 Injection in Healthy Volunteers to Evaluate Safety and Tolerability of a Single Subcutaneous Injection in Low-Body-Weight Subjects; and Pharmacokinetics at Different Subcutaneous Injection Sites at the Same DoseNov 6, 2026NCT07920861
- A Study of GKL-006Allo Injection in Patients With Ankylosing SpondylitisNov 4, 2026NCT07915544
- SLAMF1 Gene Expression in Ankylosing SpondylitisOct 30, 2026NCT07907913
- Phase Ia Study of MST-931 in Healthy Adult SubjectsOct 29, 2026NCT07903493
- Ivarmacitinib With or Without Celecoxib for Ankylosing SpondylitisOct 26, 2026NCT07894497
Show 2 moreShow fewer
- Nurse-Led Exercise Program for Older Adults With Ankylosing SpondylitisOct 23, 2026NCT07891507
- Posture Exercises in Ankylosing SpondylitisOct 16, 2026NCT07879157
Studies
Recruiting first, then most recently updated. Showing 50 of 531. Browse all 531 → or search them.
- A Study of HB0017 Injection in Healthy Volunteers to Evaluate Safety and Tolerability of a Single Subcutaneous Injection in Low-Body-Weight Subjects; and Pharmacokinetics at Different Subcutaneous Injection Sites at the Same DoseRecruitingNCT07920861Phase 11 country
- Pain Phenotyping of Rheumatic Diseases - An Observational StudyRecruitingNCT078294971 country
- A Study of GKL-006Allo Injection in Patients With Ankylosing SpondylitisNot yet recruitingNCT07915544Phase 11 country
- Phase Ia Study of MST-931 in Healthy Adult SubjectsRecruitingNCT07903493Phase 11 country
- SLAMF1 Gene Expression in Ankylosing SpondylitisNot yet recruitingNCT07907913
- Natural History and Development of SpondyloarthritisRecruitingNCT014226941 country
- Ivarmacitinib With or Without Celecoxib for Ankylosing SpondylitisNot yet recruitingNCT07894497Phase 4
- Posture Exercises in Ankylosing SpondylitisNot yet recruitingNCT07879157Not applicable1 country
- A Randomized Trial of Ultrasound-Guided Acupotomy for Ankylosing SpondylitisRecruitingNCT07578220Not applicable1 country
- Surface Topography and Radiographic Spinal Damage in Radiographic Axial SpondyloarthritisRecruitingNCT078553931 country
- Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an Inflatable Positioning Device: Technical Note and Retrospective Single-centre Case SeriesNot yet recruitingNCT07847320
- Effects of Land- and Water-Based Exercise in Axial SpondyloarthritisNot yet recruitingNCT07833033Not applicable1 country
- Exactech Shoulder Post Market Clinical Follow-up StudyRecruitingNCT056037286 countries
- Ocular Surface Changes and Meibomian Gland Dysfunction in Rheumatologic PatientsNot yet recruitingNCT07810569
- Mass Spectrometry-based Immune Profiling in Autoimmune DiseasesEnrolling by invitationNCT071882851 country
- Postural Biofeedback and Exercise in Axial SpondyloarthritisNot yet recruitingNCT07776652Not applicable1 country
- Real-world Study on Secukinumab Effectiveness in Biologic-naïve Ankylosing Spondylitis (AS) Patients in Korea.RecruitingNCT069052881 country
- Fecal Microbiota Transplantation in Axial SpondyloarthritisRecruitingNCT06451588Phase 21 country
- 15-Hydroxyprostaglandin Dehydrogenase in Osteoarthritis and Ankylosing SpondylitisNot yet recruitingNCT07751263
- Korean Post-marketing Surveillance for Xeljanz XRRecruitingNCT048767811 country
- A Study to Assess the Safety of Subcutaneous Secukinumab for Treatment in Adult Indian Participants With Axial Spondyloarthritis (axSpA), Ankylosing Spondylitis (AS), and Non-Radiographic Axial Spondyloarthritis (nr-axSpA)Not yet recruitingNCT07737730
- Evaluation of Serum IL-41 Level in Patients With Ankylosing Spondylitis and Psoriatic ArthritisNot yet recruitingNCT07648836
- Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyRecruitingNCT07138898Phase 21 country
- Assessment of Peripheral Neuropathy in Ankylosing SpondylitisNot yet recruitingNCT076419201 country
- An Investigation of the Effect of Smartphone Usage Levels on Cervical Posture, Tongue Pressure, Balance, and Neck Disability in Individuals With Rheumatoid Arthritis and Ankylosing SpondylitisRecruitingNCT076275421 country
- Efficacy of the Erector Spinae Plane Block for Persistent Back Pain in Patients With Ankylosing SpondylitisRecruitingNCT07633730Not applicable1 country
- Safety and Efficacy of Allogeneic Bone Marrow MSCs in Ankylosing SpondylitisNot yet recruitingNCT07632599Phase 11 country
- Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint InhibitorsRecruitingNCT047513961 country
- Vilamakitug in Spondyloarthritis Placebo-controlled Investigation for EfficacyNot yet recruitingNCT06526377Phase 2
- Effectiveness and Safety of Acemetacin in Active Axial Spondyloarthritis: A Real-world StudyNot yet recruitingNCT07582146Phase 41 country
- Exploratory Investigation of the Acceptance and Utility of 14-day Trial Periods and Application-related Outcome Measurement (AbEM) Within the Routine Prescription of the DiGA Axia.RecruitingNCT07561255Not applicable1 country
- Evaluating the Efficacy and Short-Term Prognosis of Integrated Traditional Chinese and Western Medicine for Ankylosing Spondylitis(AS): A Protocol for a Cohort StudyRecruitingNCT075562241 country
- Oxidative Stress in Autoimmune Rheumatic DiseasesRecruitingNCT075365291 country
- A Phase I/Ⅱ Clinical Trial for Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in the Treatment of Ankylosing SpondylitisNot yet recruitingNCT07534644Phase 1/2
- The Disease Progression of Chinese Axial Spondyloarthritis in a Real-word Cohort StudyRecruitingNCT068446431 country
- Integrated Traditional Chinese and Western Medicine for Ankylosing Spondylitis (AS): A Cohort Study Protocol Focusing on Spondyloarthritis Research Consortium of Canada (SPARCC) Scoring SystemRecruitingNCT075097751 country
- Impact of Low Back Pain Phenotypes on Function and Quality of Life in Ankylosing SpondylitisRecruitingNCT075107891 country
- TNFAIP3 Gene Expression in Ankylosing Spondylitis and Psoriatic Arthritis Patients and Its Relation to Disease ActivityNot yet recruitingNCT07507487Not applicable
- Effectiveness of Telerehabilitation in Ankylosing SpondylitisRecruitingNCT07503327Not applicable1 country
- Deep Breathing Combined With Core Stability Exercises in the Treatment of Patients With Ankylosing SpondylitisRecruitingNCT07262294Not applicable1 country
- Rheumatology Patient Registry and BiorepositoryRecruitingNCT044020861 country
- Ankylosing SpondylitisNot yet recruitingNCT07396194
- Expression of Tim-3 on Neutrophils in Ankylosing SpondylitisNot yet recruitingNCT073838051 country
- A Study Evaluating the Efficacy of Secukinumab 300mg in Chinese Adults With Active Ankylosing SpondylitisRecruitingNCT05303285Phase 41 country
- Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation ResearchRecruitingNCT048066201 country
- The Effect of Exercise on Serum Irisin Levels and Clinical Parameters in Patients With Axial Spondyloarthritis.Not yet recruitingNCT07327073Not applicable1 country
- Skin Autofluorescence Assessment of Advanced Glycation End Products in Rheumatic DiseasesNot yet recruitingNCT07329556
- Efficacy and Safety Phase III Clinical Study of VC005 Tablets in Subjects With Active Ankylosing Spondylitis.RecruitingNCT07172360Phase 31 country
- Effects of Phytocannabinoids on Immune Response and Autophagy During Chronic Immune-mediated Inflammatory DiseasesRecruitingNCT068423161 country
- A Study to Evaluate the Efficacy and Safety of 608 in Adult Subjects With Active Ankylosing Spondylitis(AS)RecruitingNCT07261644Phase 31 country