Hypertriglyceridemia clinical trials
The registry lists 294 studies for Hypertriglyceridemia across more than 10 countries. 38 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Completed
- 192
- Recruiting
- 24
- Status unknown
- 21
- Active, not recruiting
- 17
- Terminated
- 16
- Not yet recruiting
- 12
Phase
- Phase 2
- 63
- Phase 3
- 60
- Phase 4
- 36
- Phase 1
- 35
- Early Phase 1
- 4
Where
- United States
- 136
- Canada
- 43
- China
- 26
- France
- 18
- Hungary
- 17
- Germany
- 17
Who runs them
AstraZeneca (13) · Ionis Pharmaceuticals, Inc. (9) · Arrowhead Pharmaceuticals (8) · National Heart, Lung, and Blood Institute (NHLBI) (5) · Essentialis, Inc. (5) · GlaxoSmithKline (5) · Regeneron Pharmaceuticals (5) · Montana State University (4)
Studies
Recruiting first, then most recently updated. Showing 50 of 294 — search for more.
- Plasma Lipids-Dependent Vitamin E Metabolism During Dynamic HyperlipidemiaNot yet recruitingNCT07715890Not applicable1 country
- A Study of Solbinsiran (LY3561774) in Participants With Severe HypertriglyceridemiaRecruitingNCT07269210Phase 24 countries
- Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute PancreatitisRecruitingNCT06880770Phase 327 countries
- A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory DyslipidemiasRecruitingNCT07491172Phase 14 countries
- Comparing Two Low-Carbohydrate Diets With a Standard Diet in Type 2 DiabetesNot yet recruitingNCT07801378Not applicable
- A Study to Assess the Safety, Tolerability and Efficacy of ION775RecruitingNCT07604974Phase 22 countries
- Study of MAR001 in Adults With Elevated Triglycerides and Remnant CholesterolRecruitingNCT07028749Phase 24 countries
- Icosapent Ethyl for High-Risk Coronary Plaques Assessed by 18F-NaF PET/CTNot yet recruitingNCT07762755Phase 41 country
- Long-Term Safety and Efficacy of Plozasiran in Adults With HypertriglyceridemiaRecruitingNCT06822790Phase 323 countries
- Pemafibrate for Symptomatic ICAS RCTRecruitingNCT07562178Not applicable1 country
- Culturally Adapted Dietary Clinical Trial in PRRecruitingNCT05962372Not applicable1 country
- Cardiovascular-Kidney-Metabolic Syndrome RegistryNot yet recruitingNCT07718789
- Phase 1b Study of VERVE-201 in Patients With Refractory HyperlipidemiaRecruitingNCT06451770Phase 16 countries
- A Phase III Study to Evaluate the Efficacy and Safety of of DR10624 in Subjects With Severe HypertriglyceridemiaNot yet recruitingNCT07693777Phase 31 country
- A Phase 3 Trial of DR10624 Versus Placebo in Patients With Severe HypertriglyceridemiaNot yet recruitingNCT07680829Phase 31 country
- CS-121 APOC3 Base Editing in Severe HypertriglyceridemiaNot yet recruitingNCT07657780Early Phase 11 country
- A Trial to Evaluate the Efficacy and Safety of DR10624 in Patients With Hypertriglyceridemia and Carotid Atherosclerotic PlaqueEnrolling by invitationNCT07050134Not applicable1 country
- A Study of SHR-1918 In Participants With HypertriglyceridemiaRecruitingNCT07349615Phase 31 country
- GLP-1 Agonists for Prevention of Recurrent Hypertriglyceridemic Acute PancreatitisNot yet recruitingNCT07617155Phase 41 country
- Effect of Consuming n-3 Polyunsaturated Fatty Acids Rich Foods on Triglyceride Concentration and Lipoprotein CompositionRecruitingNCT07004777Not applicable1 country
- Russian Extreme Hypertriglyceridemia RegistryRecruitingNCT075089301 country
- First-in-Human Study of ISH0688: Safety, Tolerability, Pharmacokinetics, and PharmacodynamicsNot yet recruitingNCT07505043Phase 11 country
- CS-121 APOC3 Base Editing in FCSRecruitingNCT07176923Early Phase 11 country
- Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans With Different Insulin Resistance PhenotypesRecruitingNCT05743868Not applicable1 country
- a Phase 1b/2a Study of JMT202 Injection in Participants With HypertriglyceridemiaRecruitingNCT07140809Phase 1/21 country
- A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant CholesterolRecruitingNCT07199309Phase 21 country
- Differential Thrombogenesis by EPA and DHA Mediated by HDLRecruitingNCT06494488Early Phase 11 country
- Interest of High-speed Centrifugation for Measuring Anti-Xa Activity on Lipemic PlasmaRecruitingNCT072006741 country
- Multicenter Prospective Cohort Study of Hypertriglyceridemia Acute PancreatitisEnrolling by invitationNCT069760991 country
- Vitamin C Administration and Triglycerides Level in Critical Care PatientsRecruitingNCT062067591 country
- Phase 2a Study of Safety, Tolerability, and Efficacy of TLC-2716 in Subjects With Hypertriglyceridemia and NAFLDRecruitingNCT06564584Phase 21 country
- Exploring Physical Exercise for the Regulation and Control of Metabolic Disorders in College Students.Not yet recruitingNCT06555159Not applicable1 country
- Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal WomenRecruitingNCT06220266Phase 2/31 country
- A Study on the Effects of Mastiha Oil in Adults With HypertriglyceridemiaNot yet recruitingNCT06323252Not applicable
- Study of the Efficacy and Safety of EPA in Patients With Type-2 DiabetesNot yet recruitingNCT06129526Phase 41 country
- Safety Study of Fenofibrate During PregnancyRecruitingNCT058838651 country
- Abnormal Lipids - Causes and EffectsRecruitingNCT021950501 country
- Impact of Foods on Bile Acids, Metabolites, and InflammationRecruitingNCT05245357Not applicable1 country
- Compassionate Use of Metreleptin in Previously Treated People With Partial LipodystrophyActive, not recruitingNCT02262806Phase 21 country
- Compassionate Use of Metreleptin in Previously Treated People With Generalized LipodystrophyActive, not recruitingNCT02262832Phase 31 country
- Effects of DHA-NAT on Postprandial Lipidaemia in Healthy Male SubjectsCompletedNCT05953064Not applicable1 country
- Genes Involved in Lipid DisordersCompletedNCT023113351 country
- RBD5044 in Chinese Participants With HypertriglyceridemiaActive, not recruitingNCT07587788Phase 21 country
- A Pilot Study to Determine the Efficacy of a Low Carbohydrate Diet in Treatment of Adolescents With Metabolic SyndromeCompletedNCT00940966Not applicable1 country
- Expanded Access for Metreleptin for the Treatment of Diabetes Mellitus and/or Hypertriglyceridemia Associated With LipodystrophyNo longer availableNCT00677313
- Nutritional Transitions to More Plant Proteins and Less Animal Proteins: Understanding the Induced Metabolic Reorientations and Searching for Their Biomarkers (ProVegOmics)CompletedNCT04236518Not applicable1 country
- Study of Plozasiran in Adults With Severe HypertriglyceridemiaActive, not recruitingNCT06347016Phase 316 countries
- A Study of the Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)CompletedNCT06548100Phase 31 country
- Study of Plozasiran (ARO-APOC3) in Adults With Severe HypertriglyceridemiaActive, not recruitingNCT06347003Phase 317 countries
- To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe HypertriglyceridemiaCompletedNCT05852431Phase 320 countries