Drug
Megestrol Acetate clinical trials
Also written Megace, BDH 1298, SC-10363 and 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate.
A product of Megestrol; its studies count on that page too.
Keep track of what changes. Save the Megestrol Acetate studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
58 studies that test it; most in 2025 (11)
| Year | Studies |
|---|---|
| 1998 | 1 |
| 2000 | 4 |
| 2001 | 1 |
| 2002 | 1 |
| 2003 | 1 |
| 2004 | 4 |
| 2005 | 1 |
| 2006 | 5 |
| 2007 | 3 |
| 2008 | 1 |
| 2011 | 2 |
| 2013 | 1 |
| 2014 | 1 |
| 2015 | 1 |
| 2017 | 3 |
| 2018 | 1 |
| 2019 | 2 |
| 2020 | 3 |
| 2021 | 1 |
| 2022 | 4 |
| 2023 | 1 |
| 2024 | 1 |
| 2025 | 11 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 19 · Other 46
Changchun GeneScience Pharmaceutical Co., Ltd. (7) · Fudan University (5) · Xiaojun Chen (3) · Wake Forest University Health Sciences (3) · Bristol-Myers Squibb (3) · Par Pharmaceutical, Inc. (3) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Endo Pharmaceuticals (2)
Often tested with
Tested in the same studies.
Tamoxifen (3) · Rosuvastatin (2) · Metformin (2) · Paclitaxel (2) · Medroxyprogesterone Acetate (2) · Medroxyprogesterone (2) · Letrozole (2) · Levonorgestrel (2)
Studies
Open first, then newest update. How each study uses Megestrol Acetate is read from its arms, and is right about nine times in ten.
Testing it · 65
- A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)RecruitingPhase 2Merck Sharp & Dohme LLCNCT06979596Written as Megestrol acetate/Medroxyprogesterone acetate
- Megestrol Acetate for Fatigue Management in T-DXd Treated Breast CancerRecruitingPhase 3Sun Yat-sen UniversityNCT07543536Written as Megestrol Acetate + Trastuzumab Deruxtecan
- Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical HyperplasiaRecruitingPhase 2/3Xiaojun ChenNCT05316493Written as Megestrol Acetate 160 MG Oral Tablet
- Nanocrystalline Megestrol Acetate Versus Placebo for Anorexia in Patients With Unresectable Hepatocellular Carcinoma Receiving TACE Combined With Targeted and ImmunotherapyNot yet recruitingPhase 2Nanfang Hospital, Southern Medical UniversityNCT07565415Written as Nanocrystalline megestrol acetate
- Refining Fertility-sparing Treatment in Endometrial Carcinoma Based on Molecular ClassificationRecruitingPhase 2/3Fudan UniversityNCT07319429Written as Megestrol Acetate 160 MG
- Nanocrystalline Megestrol Acetate for Cachectic Stage Locally Advanced Hepatocellular CarcinomaNot yet recruitingPhase 3Changchun GeneScience Pharmaceutical Co., Ltd.NCT07356037Written as Nanocrystalline Megestrol Acetate
- Megestrol Acetate in Improving Neoadjuvant Chemotherapy-Related Weight Loss in Locally Advanced CRCRecruitingPhase 3Sixth Affiliated Hospital, Sun Yat-sen UniversityNCT06998758Written as Megestrol Acetate
- A Study on Nausea and Vomiting Caused by T-DXd in Breast Cancer PatientsNot yet recruitingPhase 4Tianjin Medical University Cancer Institute and HospitalNCT07254416Written as Megestrol Acetate
- A Prospective Real-World Observational Study of Nanocrystalline Megestrol Acetate in Patients With Cancer CachexiaRecruitingPhase 4Changchun GeneScience Pharmaceutical Co., Ltd.NCT07243379Written as Nanocrystalline Megestrol Acetate
- Nanocrystalline Megestrol Acetate in Concurrent Chemoradiotherapy for Locally Advanced Non-Small Cell Lung CancerRecruitingPhase 3Changchun GeneScience Pharmaceutical Co., Ltd.NCT07150663Written as Nano-crystalline Megestrol Acetate Oral Suspension
- Nano-crystalline Megestrol Acetate for Anorexia-Cachexia Syndrome in Advanced Lung CancerNot yet recruitingPhase 2Guangzhou Institute of Respiratory DiseaseNCT07092137Written as Nano-crystalline Megestrol Acetate Oral Suspension
- Clinical Study on Nanocrystalline Megestrol Acetate for Appetite Improvement and Weight Gain in Pre-Cachexia and Cachexia Stages Key Terminology AnalysisNot yet recruitingPhase 3Changchun GeneScience Pharmaceutical Co., Ltd.NCT06961188Written as Nano-crystalline Megestrol Acetate Oral Suspension
- Nano-crystalline Megestrol Acetate Combined With Standard Treatment Versus Standard Treatment for First-line Extensive-stage Small Cell Lung Cancer in the Cachexia PhaseNot yet recruitingPhase 3Changchun GeneScience Pharmaceutical Co., Ltd.NCT06961201Written as Nano-crystalline Megestrol Acetate Oral Suspension
- Nanocrystalline Megestrol Acetate for the Treatment of Anorexia-Cachexia Syndrome in Extensive-Stage Small Cell Lung Cancer: A Prospective, Open-Label, Single-Arm Phase II Clinical StudyNot yet recruitingPhase 2Guangzhou Institute of Respiratory DiseaseNCT06909383Written as Nanocrystalline megestrol acetate
- Nanocrystalline Megestrol for First-line Treatment of Advanced Gastric or Colorectal Cancer With Cancer-related FatigueRecruitingNot applicableChangchun GeneScience Pharmaceutical Co., Ltd.NCT06830018Written as Nano-crystalline Megestrol Acetate Oral Suspension
- Nano-crystalline Megestrol Acetate for Adjuvant Treatment in High-risk Head and Neck Squamous Cell Carcinoma After Surgery.Not yet recruitingPhase 3Changchun GeneScience Pharmaceutical Co., Ltd.NCT06772428Written as Nano-crystalline Megestrol Acetate Oral Suspension
- Evaluation of the Efficacy of Addition of Progesterone to Standard Chemotherapy in Adrenocortical Carcinoma (ACC)RecruitingPhase 2Azienda Socio Sanitaria Territoriale degli Spedali Civili di BresciaNCT05913427Written as Etoposide, doxorubicin, cisplatin and Mitotane plus Megestrol Acetate 160 MG
- Nutrition Impact on Immunotherapy of CancerRecruitingPhase 3Qingdao Central HospitalNCT06500234Written as Megestrol Acetate and olanzapine
- Prospective Study for Endometrial Carcinoma and Hyperplasia in Childbearing-age WomenRecruitingNot applicableWomen's Hospital School Of Medicine Zhejiang UniversityNCT06417736Written as Megestrol Acetate 40 MG
- Weight Management Plus Megestrol Acetate in Early-stage Endometrioid CarcinomaTerminatedPhase 2/3Xiaojun ChenNCT05316467Written as Megestrol Acetate 160 MG Oral Tablet
See all 65 studies that test Megestrol Acetate →
Given in every arm · 7 — Megestrol Acetate is usual care beside what is tested
- Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial CancersActive, not recruitingPhase 1/2National Cancer Institute (NCI)NCT05538897Written as Megestrol Acetate
- Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing HysterectomyActive, not recruitingPhase 2City of Hope Medical CenterNCT03671811Written as Megestrol Acetate
- Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial CancerActive, not recruitingPhase 2Northwestern UniversityNCT04576104Written as Megestrol Acetate
- Liraglutide Plus Megestrol Acetate in Endometrial Atypical HyperplasiaWithdrawnPhase 2/3Xiaojun ChenNCT04683237Written as Megestrol Acetate 160 MG
- Phase II Study of Everolimus Beyond ProgressionTerminatedPhase 2Emory UniversityNCT02269670Written as megestrol acetate
- Megestrol Acetate Plus LNG-IUS in Young Women With Early Endometrial CancerCompletedPhase 2/3Fudan UniversityNCT03241914Written as Megestrol Acetate
- Megestrol Acetate With or Without Mirtazapine in Treating Cancer Patients With Weight Loss or Loss of AppetiteWithdrawnPhase 2Washington University School of MedicineNCT01501396Written as Megestrol Acetate
As the comparator · 11 — what is tested is compared with Megestrol Acetate
- Progestins for the Treatment of Endometrial Cancer or Precancers of the Uterus Before Surgery, The Pro-Window TrialRecruitingPhase 2New Mexico Cancer Research AllianceNCT07436793Written as Megestrol Acetate
- Nanocrystalline Megestrol + Immunochemo As 1st-Line for ES-SCLC CachexiaNot yet recruitingPhase 2Henan Cancer HospitalNCT06793228Written as Nanocrystalline Megestrol Acetate
- Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial CancerActive, not recruitingPhase 2Fudan UniversityNCT05247268Written as Megestrol Acetate 160 MG Oral Tablet
- Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer PatientsActive, not recruitingPhase 3Alliance for Clinical Trials in OncologyNCT04939090Written as Megestrol Acetate
- Levonorgestrel-Releasing Intrauterine System (LNG-IUS) in the Management of Atypical Endometrial HyperplasiaWithdrawnPhase 3Wake Forest University Health SciencesNCT04897217Written as Megestrol Acetate
- Mirtazapine Versus Megestrol Acetate in Treatment of Anorexia-cachexia in Advanced Cancer Patients.Status unknownPhase 2Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshNCT05380479Written as Megestrol Acetate
- The Study of Oral Steroid Sulphatase Inhibitor BN83495 Versus Megestrol Acetate (MA) in Women With Advanced or Recurrent Endometrial CancerCompletedPhase 2IpsenNCT00910091Written as Megestrol Acetate (MA)
- The Safety and Effect Study of Acupuncture for Anorexia in Patients With Gastrointestinal Tract and Lung CancersStatus unknownPhase 2/3Xinqiao Hospital of ChongqingNCT02619266Written as Megestrol Acetate
- Phase 1 Study of Daewon-ES(B) & Megace in Healthy Male Volunteers Under Fasting and Fed ConditionCompletedPhase 1Asan Medical CenterNCT01456624Written as Megace
- Phase 1 Study of Daewon-ES(B) & Megace in Healthy Male Volunteers Under Fed ConditionCompletedPhase 1Daewon Pharmaceutical Co., Ltd.NCT01589562Written as Megace 800mg/20ml
- Multicenter Follow Up Study Of Subjects Who Participated In An Original Protocol Of Exemestane Vs. Megestrol Acetate In Postmenopausal Women With Metastatic Breast CancerCompletedPhase 3PfizerNCT01237327Written as Megestrol acetate
Codes
What other systems call Megestrol Acetate · ClinicalTrials.gg INT008675
- MeSH (NLM) D019290Megestrol AcetateConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) TJ2M0FR8ESMEGESTROL ACETATEConfirmed FDA, NLM, Wikidata
- RxNorm 29451Confirmed FDA, Wikidata
- Wikidata Q6808975megestrol acetateConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C1156Megestrol AcetateOne source FDA
- DrugBank DB00351One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D019290 | Megestrol Acetate | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | TJ2M0FR8ES | MEGESTROL ACETATE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 29451 | — | Confirmed FDA, Wikidata |
| Wikidata | Q6808975 | megestrol acetate | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C1156 | Megestrol Acetate | One source FDA |
| DrugBank | DB00351 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.