Drug
Estetrol clinical trials
Also written E4.
Includes 1 study of Estetrol monohydrate.
- studies test it
- 23
- open now
- 1
- in phase 3
- 4
- first study started
- 2005
Keep track of what changes. Save the Estetrol studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
23 studies that test it; most in 2016 (6)
| Year | Studies |
|---|---|
| 2005 | 1 |
| 2007 | 2 |
| 2015 | 1 |
| 2016 | 6 |
| 2017 | 2 |
| 2018 | 2 |
| 2019 | 3 |
| 2020 | 1 |
| 2021 | 1 |
| 2023 | 1 |
| 2024 | 3 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 9
- Phase 2
- 9
- Phase 3
- 4
- Phase 4
- 2
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 17 · Other 6
Estetra (11) · Pantarhei Oncology B.V. (3) · Pantarhei Bioscience (3) · Donesta Bioscience (2) · Chulalongkorn University (1) · University of Palermo (1) · Andrew Zakhari (1) · NEURALIS s.a. (1)
Often tested with
Tested in the same studies.
Drospirenone (8) · Nomegestrol acetate (1) · Megestrol (1) · Estradiol (1) · Ethinyl Estradiol (1) · Dienogest (1) · Valine (1) · Desogestrel (1)
Studies
Open first, then newest update. How each study uses Estetrol is read from its arms, and is right about nine times in ten.
Testing it · 23
- Estetrol/Drospirenone to Reduce the Average Size of EndometriomasRecruitingPhase 4Andrew ZakhariNCT05837624Written as Estetrol/Drospirenone
- Estetrol for the Treatment of Female Sexual Arousal Disorder in Postmenopausal WomenCompletedPhase 2EstetraNCT06308614Written as Estetrol
- Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort II)CompletedPhase 3EstetraNCT04090957Written as Estetrol oral tablet
- "Quick-starting" of a New Combined Hormonal Contraceptive Pills, 15 mg Estetrol/3 mg Drospirenone VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation InhibitionCompletedNot applicableChulalongkorn UniversityNCT06396221Written as Estetrol 15 mg/Drospirenone 3 mg (24/4)
- Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort Study I)CompletedPhase 3EstetraNCT04209543Written as Estetrol
- E4Relief (Response to Estetrol in Life Improvement for MEnopausal-associated Hot Flushes)CompletedPhase 2Donesta BioscienceNCT02834312Written as Estetrol
- The Use of Drospirenone/Estetrol, Nomegestrol Acetate/Estradiol and Ethinylestradiol/Dienogest in Random Start Rapid Endometrial PreparationCompletedPhase 4University of PalermoNCT06324851Written as Drospirenone / Estetrol
- Effect of Estetrol Monohydrate (E4) on QTc IntervalCompletedPhase 1EstetraNCT04819906Written as Estetrol 20 mg
- E4/DRSP Ovarian Function Inhibition StudyCompletedPhase 2EstetraNCT03091595Written as 15 mg E4/3 mg DRSP
- Estetrol (E4) for the Treatment of Patients With Confirmed SARS-COV-2 InfectionStatus unknownPhase 2NEURALIS s.a.NCT04801836Written as Estetrol monohydrate 15 mg
- Evaluation of Effects of Estetrol on Testosterone Suppression and Quality of Life in Prostate Cancer Patients Treated With an LHRH Agonist.CompletedPhase 2Pantarhei Oncology B.V.NCT03361969Written as Estetrol
- Assessment of Safety and Efficacy of Estetrol in Postmenopausal Women With Advanced Estrogen Receptor Positive (ER+) Breast CancerCompletedPhase 1/2Pantarhei Oncology B.V.NCT02718144Written as Estetrol
- E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - United States/Canada StudyCompletedPhase 3EstetraNCT02817841Written as 15 mg E4/3 mg DRSP
- E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - EU/Russia StudyCompletedPhase 3EstetraNCT02817828Written as 15 mg E4/3 mg DRSP
- Effect of Food on the Bioavailability of 30 mg Estetrol (E4) Tablet in Healthy Postmenopausal Female VolunteersCompletedPhase 1Donesta BioscienceNCT03798197Written as 30 mg estetrol (E4)
- Study Conducted to Further Understand the Elimination Pathways, Metabolite Profile and PK Profile of 14C-estetrolCompletedPhase 1EstetraNCT02720224Written as Estetrol
- Estetrol (E4)/Drospirenone (DRSP) Drug-drug Interaction (DDI) StudyCompletedPhase 1EstetraNCT03512860Written as E4/DRSP
- "E4/DRSP Endocrine Function, Metabolic Control and Hemostasis Study"CompletedPhase 1/2EstetraNCT02957630Written as 15 mg E4/3 mg DRSP
- Evaluation of Safety and Efficacy of Estetrol in Healthy MenCompletedPhase 1Pantarhei Oncology B.V.NCT02718378Written as estetrol
- Effect of Food on the Bioavailability of 15 mg Estetrol/3 mg Drospirenone Tablets in Healthy Female VolunteersCompletedPhase 1EstetraNCT02852681Written as 15 mg E4/3 mg DRSP
See all 23 studies that test Estetrol →
As the comparator · 1 — what is tested is compared with Estetrol
Codes
What other systems call Estetrol · ClinicalTrials.gg INT007440
- MeSH (NLM) D004953EstetrolConfirmed NLM, Wikidata
- UNII (FDA) ENB39R14VFESTETROL ANHYDROUSConfirmed FDA, NLM, Wikidata
- RxNorm 2539031One source FDA
- Wikidata Q5401078estetrolConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C68928Therapeutic EstetrolOne source FDA
- DrugBank DB12235One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D004953 | Estetrol | Confirmed NLM, Wikidata |
| UNII (FDA) | ENB39R14VF | ESTETROL ANHYDROUS | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2539031 | — | One source FDA |
| Wikidata | Q5401078 | estetrol | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C68928 | Therapeutic Estetrol | One source FDA |
| DrugBank | DB12235 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.