Hidradenitis Suppurativa clinical trials
The registry lists 285 studies for Hidradenitis Suppurativa across more than 10 countries. 88 are recruiting or about to start. 247 of them are mainly about Hidradenitis Suppurativa (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Status
Who runs them
Novartis Pharmaceuticals (21) · AbbVie (15) · Incyte Corporation (12) · Henry Ford Health System (7) · University of Miami (6) · UCB Biopharma SRL (6) · Montefiore Medical Center (5) · MoonLake Immunotherapeutics AG (5)
What is being tested here
Drugs under test in Hidradenitis Suppurativa studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Povorcitinib | 2 | 4 | 8 |
| Secukinumab | 2 | 3 | 6 |
| Remibrutinib | 2 | 3 | 5 |
| Roflumilast | 2 | 0 | 3 |
| Bimekizumab | 1 | 4 | 6 |
| Ruxolitinib | 1 | 2 | 5 |
| Sonelokimab | 1 | 4 | 5 |
| Lutikizumab | 1 | 1 | 3 |
| Brivekimig | 1 | 0 | 2 |
| Botulinum toxin type A | 1 | 0 | 2 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 6 open · JAK inhibitors 3 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa · Phase 3 · AbbVie
- Dec 2026A Study to Assess the Pharmacokinetics and Safety of Bimekizumab in Children and Adolescents With Moderate to Severe Hidradenitis Suppurativa · Phase 3 · UCB Biopharma SRL
- Dec 2026A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa · Phase 3 · Incyte Corporation
- Feb 2027Efficacy of an Adapted Antibiotherapy in Hurley Stage 2 Hidradenitis Suppurativa Patients · Phase 3 · Institut Pasteur
- May 2027A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (RECHARGE 1) · Phase 3 · Novartis Pharmaceuticals
- Jun 2027A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa · Phase 3 · Novartis Pharmaceuticals
- Aug 2027A Study Evaluating BFB759 in Moderate to Severe Hidradenitis Suppurativa · Phase 3 · Bluefin Biomedicine, Inc.
- Nov 2026Study of Single Doses of SBT777101 in Subjects With Hidradenitis Suppurativa · Sonoma Biotherapeutics, Inc.
- Nov 2026Acceptability of MBSR for People With HS · University of California, San Francisco
- Nov 2026Comparison of the Clinical Efficacy and Safety of Topical and Subcutaneous Injection of Secukinumab in HS · Peking Union Medical College
Who these studies take
Of the 61 Hidradenitis Suppurativa studies recruiting now, 33 (54%) set no upper age limit and 17 (28%) stop at 75 or younger. 13 (21%) take children under 18. 1 (2%) are for women only and 0 (0%) for men only; 12 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 7 (11%) | 7 (11%) |
| 18 | 60 (98%) | 59 (97%) |
| 30 | 60 (98%) | 59 (97%) |
| 40 | 60 (98%) | 59 (97%) |
| 50 | 59 (97%) | 58 (95%) |
| 65 | 57 (93%) | 56 (92%) |
| 75 | 51 (84%) | 50 (82%) |
| 85 | 41 (67%) | 40 (66%) |
Across all 285 studies, recruiting or not: 26% stop at 75 or younger and 13% at 65; 18% take children; 2% are for women only and 0% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hidradenitis Suppurativa studies take
Of 54 phase 2 interventional studies under Hidradenitis Suppurativa, half reached primary completion within 15 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 17 mo11–29 · 20 studies | — | — |
| Phase 2 | 15 mo11–24 · 54 studies | 15 mo10–20 · 44 studies | — |
| Phase 3 | 25 mo20–38 · 26 studies | — | — |
| Interventional, no phase | 17 mo11–31 · 25 studies | — | — |
| Observational | 34 mo25–… · 44 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting3
- Efficacy and Safety of Olatorepatide Versus Placebo in Adults With Moderate to Severe Hidradenitis Suppurativa Living With Overweight or ObesityNov 10, 2026NCT07830329
- A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial)Oct 19, 2026NCT07766005
- A Study to Explore the Tissue Level Effects of Remibrutinib in Adults With Moderate to Severe HSOct 16, 2026NCT07855276
Results posted1
Newly registered3
- A Study of SL-325 in Participants With Hidradenitis SuppurativaNov 12, 2026NCT07934017
- Early Pathophysiology of Hidradenitis Suppurativa and Prediction of the Risk of Progression: a Prospective CohortNov 6, 2026NCT07920848
- Acceptability of MBSR for People With HSOct 29, 2026NCT07903948
Studies
Recruiting first, then most recently updated. Showing 50 of 285. Browse all 285 → or search them.
- A Study of SL-325 in Participants With Hidradenitis SuppurativaNot yet recruitingNCT07934017Phase 2
- A Study to Explore the Tissue Level Effects of Remibrutinib in Adults With Moderate to Severe HSRecruitingNCT07855276Phase 11 country
- A Real-world Study of Patients With Hidradenitis Suppurativa and High Cardiovascular Risk or Established Coronary Plaque Treated With SecukinumabNot yet recruitingNCT07454889
- Efficacy and Safety of Olatorepatide Versus Placebo in Adults With Moderate to Severe Hidradenitis Suppurativa Living With Overweight or ObesityRecruitingNCT07830329Phase 21 country
- An Extension Study to Assess Safety and Efficacy of Remibrutinib in Participants With Moderate to Severe HSRecruitingNCT07665437Phase 312 countries
- Early Pathophysiology of Hidradenitis Suppurativa and Prediction of the Risk of Progression: a Prospective CohortNot yet recruitingNCT07920848Not applicable
- Rollover Study for Participants Previously Enrolled in Clinical Trials of PovorcitinibRecruitingNCT06855498Phase 320 countries
- ORKA-002 Versus Placebo in Participants With Moderate-to-Severe Hidradenitis SuppurativaRecruitingNCT07783542Phase 22 countries
- Collection of Samples From Subjects With Various Skin Conditions and Healthy VolunteersRecruitingNCT059949761 country
- A Study of Early Secukinumab Treatment in Moderate to Severe Hidradenitis Suppurativa PatientsNot yet recruitingNCT07690319
- A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial)RecruitingNCT07766005Phase 22 countries
- A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis SuppurativaRecruitingNCT07225569Phase 215 countries
- Safety and Efficacy of Soquelitinib in Adults With Hidradenitis SuppurativaRecruitingNCT07828860Phase 11 country
- Brivekimig for the Treatment of Moderate to Severe Hidradenitis SuppurativaRecruitingNCT07170917Phase 219 countries
- Safety and Efficacy of Roflumilast Foam 0.3% in Adolescent and Adult Subjects With Hidradenitis SuppurativaRecruitingNCT07689188Phase 21 country
- Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis SuppurativaRecruitingNCT07213973Phase 22 countries
- Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis SuppurativaRecruitingNCT07049575Phase 11 country
- Global Healthcare Study on Hidradenitis SuppurativaRecruitingNCT076597691 country
- Regulation of Inflammatory Genes in Hidradenitis SuppurativaRecruitingNCT055071251 country
- Establishing Personalized Phage Therapy and Its Comparative Cost in Difficult-to-treat Infections (EPHICACI)RecruitingNCT063683881 country
- A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)RecruitingNCT06888193Phase 15 countries
- Botulinum Toxin Blockade of Neuronal Signals to Immune Cells as a Novel Treatment for Hidradenitis SuppurativaNot yet recruitingNCT07756346Phase 21 country
- An Observational Study of Patients With Dermatologic DiseaseNot yet recruitingNCT077481691 country
- Targeting Nociceptors in Hidradenitis SuppurativaRecruitingNCT054037101 country
- Study of Efficacy and Safety of Secukinumab in Chinese Adult Patients With Moderate to Severe Hidradenitis SuppurativaRecruitingNCT07489573Phase 41 country
- Skin-in-Sight: a Longitudinal Cohort Infrastructure for Standardized Remote Monitoring and the Evaluation of Digital Care Innovations in Chronic Skin DiseasesNot yet recruitingNCT078041341 country
- Urinary Bladder Matrix (UBM) RegistryNot yet recruitingNCT07805798
- Capsule Microbiota Transplant Therapy for Hidradenitis SuppurativaRecruitingNCT06058520Early Phase 11 country
- Mediterranean Dietary Intervention for HSNot yet recruitingNCT07800416Not applicable1 country
- Evaluate the Safety and Efficacy of Subcutaneous Siplizumab in the Treatment of Hidradenitis Suppurativa.RecruitingNCT06326476Early Phase 11 country
- Determinants of Chronic Inflammatory Skin Disease TrajectoriesRecruitingNCT059281691 country
- A Study to Explore the Safety, Tolerability, Efficacy, and Pharmacokinetics of LT-002-158 Tablets in Chinese Adult Patients With Hidradenitis SuppurativaRecruitingNCT06932003Phase 1/21 country
- Expanded Access to UpadacitinibAvailableNCT04159597
- A Proof-of-Concept Study of LAD328 in Adults With Hidradenitis SuppurativaRecruitingNCT07547813Phase 21 country
- Exploration of Brain Functional Networks in Patients With Hidradenitis Suppurativa Using fMRIRecruitingNCT077556701 country
- A Study to Assess NAV-240 in Adult Participants With Hidradenitis SuppurativaRecruitingNCT07384975Phase 28 countries
- Long Term Observational Study to Collect in a Real-world populatIon Data on the Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe HS Within the Italian PopulationRecruitingNCT075434191 country
- Myriad™ Augmented Soft Tissue Reconstruction RegistryRecruitingNCT052439661 country
- The Safety and Efficacy of Roflumilast Foam in HSRecruitingNCT07263230Phase 21 country
- FEcal tranSplantation in HidradeniTIs suppuratiVA : a piLot StudyNot yet recruitingNCT07668713Phase 11 country
- Real-world Secukinumab Outcomes in Canadian HS PatientsRecruitingNCT072820151 country
- Identification of Cutaneous and Blood Biomarkers Predictive of Response to Systemic Treatments During Chronic Inflammatory Skin DiseasesRecruitingNCT065994111 country
- A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Moderate to Severe Hidradenitis SuppurativaEnrolling by invitationNCT07007637Phase 316 countries
- Pelashield™ PainGuard™ vs Restrata® in HS SurgeryRecruitingNCT07316192Not applicable1 country
- Radiotherapy for Refractory Hidradenitis SuppurativaRecruitingNCT07414550Not applicable1 country
- A Study of LAD191 in Adults With Hidradenitis SuppurativaRecruitingNCT07151937Phase 21 country
- Clinical and Biological Characteristics of Hidradenitis SuppurativaRecruitingNCT039676001 country
- Hidradenitis Suppurativa Prospective Observational Registry and Biospecimen RepositoryRecruitingNCT041155661 country
- Nd:YAG vs Alexandrite Laser Treatment in Hidradenitis SuppurativaNot yet recruitingNCT06960447Not applicable
- A Single-center, Prospective, Self-controlled, Observational Real-world Study of the Efficacy and Safety of Anti-IL-17A/F Monoclonal Antibody Combined With Non-ablative Dot Laser for the Treatment of Mild to Moderate Hidradenitis SuppurativaNot yet recruitingNCT07554014Phase 41 country