Drug
D-serine zwitterion clinical trials
- studies test it
- 25
- open now
- 4
- in phase 3
- 3
- first study started
- 2002
Keep track of what changes. Save the D-serine zwitterion studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
- D-serine
- 18
Combined with it in one product
Studies by the year they started
24 studies that test it; most in 2009 (4)
| Year | Studies |
|---|---|
| 2002 | 1 |
| 2003 | 2 |
| 2004 | 1 |
| 2005 | 2 |
| 2006 | 1 |
| 2009 | 4 |
| 2011 | 1 |
| 2012 | 1 |
| 2013 | 1 |
| 2014 | 2 |
| 2019 | 1 |
| 2021 | 2 |
| 2022 | 1 |
| 2025 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 5
- Phase 2
- 15
- Phase 3
- 3
- Phase 4
- 2
- No phase
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 25
Nathan Kline Institute for Psychiatric Research (5) · Herzog Hospital (5) · New York State Psychiatric Institute (2) · Yale University (2) · Hadassah Medical Organization (2) · André Schmidt (1) · Johns Hopkins University (1) · China Medical University Hospital (1)
Often tested with
Tested in the same studies.
Riluzole (1) · Sarcosine (1) · Modafinil (1) · Psilocybin (1)
Studies
Open first, then newest update. How each study uses D-serine zwitterion is read from its arms, and is right about nine times in ten.
Testing it · 25
- Cognitive Strategies in Early Psychosis 2RecruitingPhase 3University of MinnesotaNCT07263022Written as D-serine solution
- D-SPARK: A Clinical Trial of D-Serine for Modifying Parkinson's Disease ProgressionRecruitingPhase 2Haukeland University HospitalNCT07312110Written as D-serine
- Pharmacologic Augmentation of TMS for Depression With D-serineRecruitingPhase 1Mclean HospitalNCT06876129Written as D-serine
- Safety and Psychological Effects of Psilocybin and D-Serine Formulation in Healthy VolunteersRecruitingPhase 1Hadassah Medical OrganizationNCT07079930Written as Psilocybin and D-Serine
- D-serine AudRem: R33 PhaseSuspendedPhase 1/2New York State Psychiatric InstituteNCT05046353Written as D-serine
- D-serine Supplementation for DepressionCompletedNot applicableAndré SchmidtNCT04721249Written as D-serine
- The Effect of D-serine as add-on Therapy in Recent-onset PsychosisTerminatedNot applicableDragos IntaNCT04140773Written as D-serine
- D-serine Augmentation of NeuroplasticityCompletedPhase 1/2New York State Psychiatric InstituteNCT03711500Written as D-serine
- D-serine and Cognitive Remediation in SchizophreniaCompletedPhase 2Nathan Kline Institute for Psychiatric ResearchNCT02156908Written as D-serine
- Safety and Effectiveness of D-serine in SchizophreniaCompletedPhase 2Nathan Kline Institute for Psychiatric ResearchNCT00322023Written as D-serine
- D-Serine Treatment For Tardive DyskinesiaStatus unknownNot applicableHerzog HospitalNCT01804920Written as D-serine
- Developing New Treatments for Tourette Syndrome: Therapeutic Trials With Modulators of Glutamatergic NeurotransmissionCompletedPhase 4Johns Hopkins UniversityNCT01018056Written as D-serine
- D-serine for the Schizophrenia ProdromeCompletedPhase 2Nathan Kline Institute for Psychiatric ResearchNCT00826202Written as D-serine
- Biomarkers in SchizophreniaCompletedPhase 2Nathan Kline Institute for Psychiatric ResearchNCT00817336Written as D Serine
- D-Serine Treatment of Negative Symptoms and Cognitive Deficits in SchizophreniaCompletedPhase 3Yale UniversityNCT00237809Written as D-serine
- D-Serine for Cocaine Dependence PilotWithdrawnPhase 2Theresa WinhusenNCT01715051Written as D-serine
- D-serine Monotherapy for SchizophreniaCompletedPhase 2Herzog HospitalNCT00816894Written as D-serine
- N-methyl-D-aspartic Acid (NMDA) and Cognitive Remediation in SchizophreniaStatus unknownPhase 2Nathan Kline Institute for Psychiatric ResearchNCT01474395Written as D-serine
- D-serine Adjuvant Treatment for Parkinson's DiseaseCompletedPhase 4Herzog HospitalNCT00215904Written as D-serine (~2g/day)
- D-serine for Posttraumatic Stress Disorder TreatmentCompletedPhase 2Herzog HospitalNCT00215878Written as D-serine (~2g /day)
See all 25 studies that test D-serine zwitterion →
As the comparator · 1 — what is tested is compared with D-serine zwitterion
Codes
What other systems call D-serine zwitterion · ClinicalTrials.gg INT014328
- UNII (FDA) 1K77H2Z9B1SERINE, D-Confirmed FDA, Wikidata
- RxNorm 1742747Confirmed FDA, Wikidata
- Wikidata Q106345496D-serine zwitterionConfirmed FDA, Wikidata
- Wikidata Q27077119D-SerineConfirmed FDA, Wikidata
- NCI Thesaurus C61739D-SerineOne source FDA
- DrugBank DB03929One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| UNII (FDA) | 1K77H2Z9B1 | SERINE, D- | Confirmed FDA, Wikidata |
| RxNorm | 1742747 | — | Confirmed FDA, Wikidata |
| Wikidata | Q106345496 | D-serine zwitterion | Confirmed FDA, Wikidata |
| Wikidata | Q27077119 | D-Serine | Confirmed FDA, Wikidata |
| NCI Thesaurus | C61739 | D-Serine | One source FDA |
| DrugBank | DB03929 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.