Renal Insufficiency clinical trials
The registry lists 1,409 studies for Renal Insufficiency across more than 10 countries. 143 are recruiting or about to start. 726 of them are mainly about Renal Insufficiency (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 4 narrower conditions too, such as Renal Insufficiency, Chronic: 7,549 studies, 1,389 open.
ClinicalTrials.gov finds 7,871 studies for Renal Insufficiency. How that becomes 1,408 here
This page counts the studies the registry files under Renal Insufficiency, and those it files under no condition that list Renal Insufficiencythemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 7,871Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −6,009Filed under a narrower condition, counted on its own pageRenal Insufficiency, Chronic 2,920 · Kidney Failure, Chronic 1,559 · Acute Kidney Injury 1,436 · Cardio-Renal Syndrome 48
- −50List Renal Insufficiency as a condition, but the registry did not file them under itMost often written as “End Stage Renal Failure on Dialysis” (22), “Renal Failure Chronic Requiring Hemodialysis” (13), and “Renal Failure Chronic Requiring Dialysis” (3). The registry filed them under other conditions only, most often Inflammation (5) and Kidney Diseases (5).
- −426Match it another way117 name it in the title, 6 in a keyword, and 303 by a synonym or other text the search reads.
- 1,386Counted here and found by its search12 of them list Renal Insufficiency in their own words; the registry filed them under no condition.
- +22
Counted here, but its search does not find them
- Quality of Life in Pre and Post Renal Transplant in Hispanic and Non-Hispanic RecipientsNCT00856895
- Eliminating the Need for Pancreas Biopsy Using Peripheral Blood Cell-free DNANCT04166149
- Impact of Microvascular Inflammation on Kidney Allograft OutcomeNCT06496269
- Evaluation Dose Adjustments in Kidney Transplant Patients on Immediate Release and Extended Release TacrolimusNCT03760263
- Randomized Trial of 2 Antibody Induction Steroid Avoidance ProtocolsNCT01172418
- Effectiveness of 20m-MB in KTR Symptom ControlNCT05809440
- The Learning Curve for Retroperitoneoscopic Donor NephrectomyNCT05790746
- Belatacept 3 Month Post Transplant Conversion StudyNCT02213068
- Clinical Pharmacy Guided Patient Counselling and Adherence Support on Renal Transplant RecipientsNCT04715412
- Utility of a Novel Dd-cfDNA Test to Detect Injury in Renal Post-Transplant PatientsNCT03765203
- Effects of Sevoflurane and Desflurane on TregNCT02559297
- Tacrolimus/Everolimus Versus Tacrolimus/Enteric-Coated Mycophenolate SodiumNCT01680861
- Desensitization Protocol for Deceased Donor ListNCT01642225
- Reducing Donor Specific Antibody (DSA) Strength in Maintenance Kidney Transplant Recipients (DSA Study)NCT01044303
- EASE-SOT Pilot StudyNCT06396702
- XM-One Study for Living Donor ProgramNCT01679184
- A Pilot Study to Assess the Safety and Efficacy of Alefacept in de Novo Kidney Transplant RecipientsNCT01163799
- Real-time Monitoring of Kidney Grafts on Hypothermic Machine PerfusionNCT04619732
- Mitra v Fingerprick Tacrolimus CreatinineNCT03601208
- Minimally Invasive Kidney TransplantationNCT03322709
- 1,408The count on this page
Get an email when these change. Save the Renal Insufficiency studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Novartis Pharmaceuticals (30) · Pfizer (25) · AstraZeneca (23) · Merck Sharp & Dohme LLC (22) · Massachusetts General Hospital (15) · Fresenius Medical Care Deutschland GmbH (15) · GlaxoSmithKline (14) · Astellas Pharma Inc (13)
What is being tested here
Drugs under test in Renal Insufficiency studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cyclophosphamide | 3 | 1 | 10 |
| Dexamethasone | 2 | 1 | 8 |
| Isatuximab | 2 | 0 | 3 |
| Dapagliflozin | 1 | 3 | 8 |
| Rituximab | 1 | 0 | 6 |
| Empagliflozin | 1 | 1 | 5 |
| Furosemide | 1 | 1 | 5 |
| Bortezomib | 1 | 0 | 5 |
| Terlipressin | 1 | 1 | 3 |
| Dexmedetomidine | 1 | 0 | 3 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 3 open · SGLT2 inhibitors 3 open · Alkylating agents 3 open · Diuretics 2 open · Corticosteroids 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026A Study to Evaluate Migalastat in Fabry Subjects With Amenable GLA Variant and Renal Disease · Phase 3 · Amicus Therapeutics
- Jul 2027The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD · Phase 3 · University Medical Center Groningen
- Nov 2026Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or Cystectomy · Nazmy Edward Seif
- Nov 2026Worldwide Assessment of Deceased Donor Kidney Utilization · Paris Translational Research Center for Organ Transplantation
- Nov 2026Hypothermic Machine Perfusion With Omnisol of Deceased Donor Kidneys Prior to Transplantation · Vivalyx GmbH
- Nov 2026Clinical Characteristics and In-Hospital Outcomes of Critically Ill Patients Receiving Hemodialysis or Continuous Venovenous Hemodiafiltration in the Emergency Department · Antalya Health Sciences University
- Nov 2026Study of Lutetium (177Lu) Vipivotide Tetraxetan in mCRPC Participants With Moderately and Severely Impaired and With Normal Renal Function · Novartis Pharmaceuticals
- Nov 2026Comparison of HYDROLINK™ and HeprAN™ mEmbranes in a Per Dialytic Heparin Weaning Strategy in Chronic Hemodialysis Patients · CHU de Reims
- Nov 2026The Study is to Investigate D-2570 in Participants With Different Levels of Kidney Function. · InventisBio Co., Ltd
- Nov 2026Renal Dysfunction in Patients With Inflammatory Bowel Disease and the General Population (NEPHRO-IBD) · Państwowy Instytut Medyczny Ministerstwa Spraw Wewnętrznych i Administracji
Who these studies take
Of the 90 Renal Insufficiency studies recruiting now, 47 (52%) set no upper age limit and 18 (20%) stop at 75 or younger. 8 (9%) take children under 18. 3 (3%) are for women only and 1 (1%) for men only; 15 (17%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (6%) | 6 (7%) |
| 18 | 77 (86%) | 75 (83%) |
| 30 | 83 (92%) | 80 (89%) |
| 40 | 86 (96%) | 83 (92%) |
| 50 | 85 (94%) | 83 (92%) |
| 65 | 85 (94%) | 83 (92%) |
| 75 | 75 (83%) | 74 (82%) |
| 85 | 60 (67%) | 59 (66%) |
Across all 1,409 studies, recruiting or not: 26% stop at 75 or younger and 9% at 65; 9% take children; 1% are for women only and 1% for men only; 27% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Renal Insufficiency studies take
Of 230 phase 1 interventional studies under Renal Insufficiency, half reached primary completion within 8 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 8 mo5–16 · 230 studies | 8 mo5–15 · 212 studies | — |
| Phase 2 | 30 mo13–34 · 26 studies | — | — |
| Phase 3 | 42 mo24–77 · 36 studies | — | — |
| Phase 4 | 37 mo20–48 · 32 studies | — | 38 mo20–67 · 29 studies |
| Interventional, no phase | 22 mo8–48 · 149 studies | 16 mo4–27 · 31 studies | 22 mo8–49 · 118 studies |
| Observational | 30 mo14–56 · 101 studies | — | 29 mo14–58 · 86 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting5
- NightWare and Cardiovascular Health in Women With PTSDNov 6, 2026NCT07021014
- A Study to Investigate the Pharmacokinetics and Safety of PKN605 in Participants With Moderate and Severe Renal Impairment Compared to Matched Control Subjects With Normal Renal FunctionNov 6, 2026NCT07797322
- Renal Impairment Pharmacokinetics (PK) Trial of AfabicinOct 26, 2026NCT07758608
- Study to Assess the Plasma Concentration of Rilzabrutinib Given as a Tablet to Adult Participants With Severe Renal Impairment Compared to Matched Participants With Normal Renal FunctionOct 23, 2026NCT07853131
- The Study is to Investigate D-2570 in Participants With Different Levels of Kidney Function.Oct 13, 2026NCT07715175
Results posted3
- Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKDOct 30, 2026NCT05614115
- A Clinical Study of Enlicitide in Participants With Severe Renal Impairment (MK-0616-032)Oct 20, 2026NCT06643377
- A Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics and Safety of VIR-2218Oct 16, 2026NCT05844228
Stopped2
- Tolerability and Safety of CARDIOMEMS™ Intracardiac Continuous Cardiac Hemodynamic Monitoring Device in Patients With Cardio Renal Syndrome With Severe Renal ImpairmentTerminatedOct 22, 2026NCT05428631
- Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for CKDTerminatedOct 20, 2026NCT05018845
Newly registered6
- A Study of Tersolisib (LY4064809) in Participants With Kidney Impairment Compared With Participants With Normal Kidney FunctionNov 9, 2026NCT07924930
- Hypothermic Kidney Machine Perfusion With OmnisolNov 6, 2026NCT07920926
- A Clinical Trial of MK-6916 in Participants With Moderate and Severe Kidney Disease Compared to Healthy Controls (MK-6916-013)Nov 6, 2026NCT07922174
- Days-Off Versus Daily Initial Peritoneal Dialysis PrescriptionNov 6, 2026NCT07922772
- A Study to Assess the Pharmacokinetics and Safety of Revumenib in Participants With Advanced Cancer and Hepatic or Renal ImpairmentNov 6, 2026NCT07923071
Show 1 moreShow fewer
- A Real World Evidence Retrospective Data Collection Study of Edoxaban and RivaroxabanOct 15, 2026NCT07874555
Studies
Recruiting first, then most recently updated. Showing 50 of 1,409. Browse all 1,409 → or search them.
- Hypothermic Kidney Machine Perfusion With OmnisolNot yet recruitingNCT07920926Not applicable
- A Study Investigating the Safety of RO7795081 and How the Body Processes RO7795081 in People With Normal or Decreased Kidney FunctionsRecruitingNCT07741604Phase 11 country
- A Study of Tersolisib (LY4064809) in Participants With Kidney Impairment Compared With Participants With Normal Kidney FunctionNot yet recruitingNCT07924930Phase 11 country
- A Study to Investigate the Pharmacokinetics and Safety of PKN605 in Participants With Moderate and Severe Renal Impairment Compared to Matched Control Subjects With Normal Renal FunctionRecruitingNCT07797322Phase 11 country
- A Study to Assess the Pharmacokinetics and Safety of Revumenib in Participants With Advanced Cancer and Hepatic or Renal ImpairmentNot yet recruitingNCT07923071Phase 1
- A Clinical Trial of MK-6916 in Participants With Moderate and Severe Kidney Disease Compared to Healthy Controls (MK-6916-013)Not yet recruitingNCT07922174Phase 1
- Days-Off Versus Daily Initial Peritoneal Dialysis PrescriptionNot yet recruitingNCT07922772Not applicable1 country
- NightWare and Cardiovascular Health in Women With PTSDRecruitingNCT07021014Not applicable1 country
- DESIR. Evaluation of the Pre-therapeutic Activity of Dihydropyrimidine dEShydrogenase (DPD) in Patients With Cancer and/or Renal FailureNot yet recruitingNCT07124403
- Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney DiseaseRecruitingNCT07271186Phase 21 country
- Renal Impairment Pharmacokinetics (PK) Trial of AfabicinRecruitingNCT07758608Phase 11 country
- Study to Assess the Plasma Concentration of Rilzabrutinib Given as a Tablet to Adult Participants With Severe Renal Impairment Compared to Matched Participants With Normal Renal FunctionRecruitingNCT07853131Phase 11 country
- Product Surveillance RegistryRecruitingNCT0152427641 countries
- SPYRAL GEMINI Pilot StudyRecruitingNCT06907147Not applicable6 countries
- STarting incrEmental Prescription of Peritoneal DialysisRecruitingNCT06642597Not applicable5 countries
- Prevent Cardiac Surgery Associated AKI TrialRecruitingNCT06620523Phase 21 country
- The Study is to Investigate D-2570 in Participants With Different Levels of Kidney Function.RecruitingNCT07715175Phase 11 country
- A Study to Investigate the Effects of Moderate or Severe Renal Impairment (RI) on VelzatinibNot yet recruitingNCT07867171Phase 1
- CAR-T Cell Therapy for Desensitization in Kidney TransplantationRecruitingNCT06056102Phase 11 country
- Study of Sulthiame (S-054502) in Participants With Renal Impairment and Matched Healthy ControlsNot yet recruitingNCT07857837Phase 11 country
- Impact of Extrarenal Myoglobin Clearance on Renal Recovery in Patients With Severe RhabdomyolysisRecruitingNCT078536771 country
- A Study to Evaluate the Pharmacokinetics and Safety of INCB161734 in Participants With Impaired Renal Function and Participants on HemodialysisNot yet recruitingNCT07854249Phase 1
- A Study to Evaluate the Impact of Renal Impairment on the Pharmacokinetics (PK) of RibupatideRecruitingNCT07793929Phase 11 country
- Delayed Tolerance Through Mixed ChimerismRecruitingNCT05900401Phase 1/21 country
- A Patient-centered Trial of a Process-of-care Intervention in Hospitalized AKI Patients: the COPE-AKI TrialRecruitingNCT05805709Not applicable1 country
- Concomitant Renal and Urinary Bladder Allograft TransplantationRecruitingNCT04626167Early Phase 11 country
- A Clinical Trial of Nemtabrutinib in Participants With Severe Kidney Disease (MK-1026-027)RecruitingNCT07734610Phase 11 country
- The Effect of Daratumumab in Patients With Monoclonal Gammopathy of Renal Significance (MGRS) in FinlandRecruitingNCT06889948Phase 21 country
- SGLT2 Inhibition in Addition to Lifestyle Intervention and Risk for Complications in Subtypes of Patients With PrediabetesRecruitingNCT06054035Phase 41 country
- Extended-Release Tacrolimus Following Liver TransplantationRecruitingNCT05242315Phase 41 country
- Differentiating True Nephrotoxicity From Pseudo-nephrotoxicity: A Prospective Comparative Study of Vancomycin Plus Piperacillin-Tazobactam vs. Meropenem Using Serum Creatinine and Cystatin-CNot yet recruitingNCT078182651 country
- Feasibility of the COMFORT (COmplex Symptom Management Intervention FOR adulTs With Advanced Kidney Disease) Intervention for Adults With Advanced Kidney Disease and Their Informal CaregiversNot yet recruitingNCT07815639Not applicable1 country
- Tenofovir Exposures in Advanced Kidney Disease StudyNot yet recruitingNCT078125711 country
- Subclinical Renal Dysfunction in Rheumatoid ArthritisNot yet recruitingNCT07805109
- PD Catheter Data CollectionRecruitingNCT071561231 country
- Analysis of Paediatric Treatments With multiFiltratePRORecruitingNCT06603324Not applicable2 countries
- Analysis of Continuous Kidney Replacement Therapy (CKRT) Treatments With multiFlux Hemofilters Using Regional Citrate Anticoagulation (RCA) or Systemic Heparin AnticoagulationNot yet recruitingNCT076795681 country
- Predictors of Rapid CKD ProgressionNot yet recruitingNCT07803237
- Clinical Performance of the Therapy Option FlexPoint of the PD Cycler Sleep•Safe HarmonyNot yet recruitingNCT06390592Not applicable
- Hypothermic Machine Perfusion With Omnisol of Deceased Donor Kidneys Prior to TransplantationRecruitingNCT07792317Not applicable1 country
- Terlipressin vs. Somatostatin in Cirrhotic Patients With Acute Variceal Bleeding and Renal DysfunctionNot yet recruitingNCT07252401Not applicable1 country
- Clinical Characteristics and In-Hospital Outcomes of Critically Ill Patients Receiving Hemodialysis or Continuous Venovenous Hemodiafiltration in the Emergency DepartmentNot yet recruitingNCT077650301 country
- Study of the Quality of Life in School Aged-children With Posterior Urethral ValvesRecruitingNCT064398621 country
- Contrast-Induced Acute Kidney Injury Prevention in Acute Heart FailureRecruitingNCT07550790Not applicable1 country
- Moda-flx Hemodialysis System™ Under Professional Care Settings by Trained Individuals and At Home by ParticipantsRecruitingNCT06613568Not applicable1 country
- A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Severe Renal Impairment or End Stage Renal DiseaseRecruitingNCT07559396Phase 11 country
- Moderate-Intensity Statin Plus Ezetimibe in CKD and ASCVDRecruitingNCT07524101Not applicable1 country
- Acute Kidney Injury in Upper GI Bleeding PatientsNot yet recruitingNCT076360831 country
- Impact of Trans-catheter Aortic Valve Implantation on Renal FunctionRecruitingNCT076267101 country
- Comparison of Citrate and Heparin Anticoagulation During Postdilution HemodiafiltrationNot yet recruitingNCT07618858Not applicable1 country