Botulinum Toxins clinical trials
Also written Botulinum toxin.
A group of medicines. Botulinum toxin type A (820 studies) is counted on its own page; this page counts the studies that name Botulinum Toxins itself.
How each study uses Botulinum Toxins is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the Botulinum Toxins studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Medicines filed under Botulinum Toxins
As reviewed, so not every one. Each counts its studies on its own page, not here.
Studies by the year they started
64 studies that test it; most in 2014 (8)
| Year | Studies |
|---|---|
| 2001 | 1 |
| 2003 | 1 |
| 2005 | 4 |
| 2007 | 1 |
| 2009 | 3 |
| 2010 | 1 |
| 2011 | 1 |
| 2012 | 4 |
| 2013 | 6 |
| 2014 | 8 |
| 2015 | 2 |
| 2016 | 5 |
| 2018 | 1 |
| 2019 | 4 |
| 2020 | 5 |
| 2021 | 2 |
| 2022 | 4 |
| 2023 | 3 |
| 2024 | 4 |
| 2025 | 3 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 4 · Other 60
Meshalkin Research Institute of Pathology of Circulation (5) · Galderma R&D (4) · Assistance Publique - Hôpitaux de Paris (3) · Henry Ford Health System (2) · National Institute of Neurological Disorders and Stroke (NINDS) (2) · University of Miami (2) · Centre Hospitalier Universitaire de Nice (1) · Antony Barbosa Institute (1)
Often tested with
Tested in the same studies.
Injection Route of Administration (1) · Adrenal Cortex Hormones (1) · Amlodipine (1) · Insulin (1) · Triamcinolone Acetonide (1) · Triamcinolone (1) · Bupivacaine (1) · Botulinum toxin type A (1)
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 4, 2 in phase 3
Studies that test Botulinum Toxins, phase 3 first.
- Dec 2026Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar MinimizationPhase 2/3 · Henry Ford Health System
- Feb 2027Botulinum Toxin Injection After Sternotomies to Improve Scar Aspect and ImpactPhase 3 · University Hospital, Bordeaux
- Dec 2026Intrapapillary Botulinum Toxin Injection for PREvention of Post-surgical PAncREactic FistulaNot applicable · Assistance Publique - Hôpitaux de Paris
- Mar 2027Botox for Chronic Pelvic PainPhase 1 · University of Miami
Studies
Open first, then newest update. How each study uses Botulinum Toxins is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 64
- Botox for Chronic Pelvic PainRecruitingPhase 1University of MiamiNCT06796985Written as Botulinum neurotoxin
- EMG-Based Evaluation of Occlusal Splint and Masseter Botox Effects on Head and Neck MusclesRecruitingPhase 4Istanbul UniversityNCT07082972Written as Botulinum toxin injection
- Botulinum Toxin Injection After Sternotomies to Improve Scar Aspect and ImpactNot yet recruitingPhase 3University Hospital, BordeauxNCT07013240Written as Botulinum toxin injection
- Low or High Botox Dilution for the Hemiplegic Gait?RecruitingPhase 1University of IoanninaNCT04630873Written as Botulinum toxin
- Injection of Botulinum Toxin for Thumb Carpometacarpal ArthritisRecruitingPhase 3Rhode Island HospitalNCT05990881Written as Botulinum toxin
- Ultrasound-guided Botulinum Toxin Injection on Cricopharyngeal Muscle DysfunctionRecruitingNot applicableZeng ChanghaoNCT06271395Written as Injectable Type A Botulinum Toxin
- Efficacy and Safety of Fractional CO2 Laser Combined With Intralesional Insulin, Botulinum Toxin or Triamcinolone Acetonide in the Treatment of Keloid: A Clinical, Dermoscopic and Immunohistochemical Study.Not yet recruitingPhase 1/2Assiut UniversityNCT06230146Written as Botulinum toxin group
- Intrapapillary Botulinum Toxin Injection for PREvention of Post-surgical PAncREactic FistulaRecruitingNot applicableAssistance Publique - Hôpitaux de ParisNCT04220931Written as botulinum toxin injection
- Male Intimate Harmonization: Efficacy, Satisfaction, and SafetyCompletedNot applicableAntony Barbosa InstituteNCT07901465Written as Botulinum toxin
- Botulinum Toxin in Raynaud's PhenomenonCompletedPhase 4Emory UniversityNCT05125029Written as Botulinum toxin
- Cyclops Syndrome After Anterior Cruciate Ligament ReconstructionTerminatedPhase 3GCS Ramsay Santé pour l'Enseignement et la RechercheNCT05008731Written as Botulinum toxin
- Comparison of Non-Surgical Treatment Options for Chronic Exertional Compartment Syndrome (CECS)CompletedPhase 2Walter Reed National Military Medical CenterNCT04409600Written as Botulinum Toxin Injection
- Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar MinimizationActive, not recruitingPhase 2/3Henry Ford Health SystemNCT05478551Written as Botulinum Toxin
- Analysis of Gait Before and After Botulinum Toxin Treatment in Patients With Focal DystoniaCompletedNot applicableUniversity Hospital, GrenobleNCT03938363Written as Botulinum Toxin injection
- Botulinum Toxin Efficiency on Spasticity of Rectus Femoris and Semitendinosus Muscles as Functional Agonist and Antagonist MusclesCompletedPhase 2/3Hospices Civils de LyonNCT00133861Written as Botulinum toxin
- Assessment of Pain After Intra-articular Botulinum Toxin Injections in Carpometacarpal Osteoarthritis of the ThumbActive, not recruitingPhase 4Centre Hospitalier Universitaire de NiceNCT04829565Written as Botulinum toxin
- The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar FormationCompletedPhase 2/3Henry Ford Health SystemNCT03887377Written as Botulinum Toxins
- The Use of Botulinum Toxin in the Management of Myofascial Pain SyndromeCompletedPhase 1/2Yassir R. Al-khannaqNCT06824324Written as intramuscular Botulinum Toxin
- Effect of Topical Botulinum Toxin Eyedrop on Palpebral FissureTerminatedPhase 4University of MiamiNCT06080438Written as Botulinum toxin
- Effect of Different Treatment Techniques on Masseter Muscle ThicknessCompletedNot applicableZonguldak Bulent Ecevit UniversityNCT06593821Written as Botulinum toxin
See all 64 studies that test Botulinum Toxins →
Given beside what is tested · 4 — Botulinum Toxins is usual care or a partner of the new treatment
- Extracorporeal Shockwave Therapy as an Additional Treatment for Spasticity Secondary to Spinal Cord InjuryRecruitingPhase 2Kessler FoundationNCT07894991Written as Botulinum toxin
- A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain ManagementNot yet recruitingEarly Phase 1HillMed Inc.NCT05062902Written as Botulinum Neurotoxin
- Imaging of 3D Innervation Zone Distribution in Spastic Muscles From High-density Surface EMG RecordingsCompletedPhase 4The University of Texas Health Science Center, HoustonNCT03302741Written as Botulinum neurotoxin (BTX)
- Dynamic Lycra Orthosis as an Adjunct to Botulinum Toxin-A Injection for Post-stroke SpasticityCompletedNot applicableMarmara UniversityNCT03546959Written as Botulinum Toxin
As the comparator · 3 — what is tested is compared with Botulinum Toxins
- Evaluation of Tibial Nerve Selective Neurotomy Compared to Botulinum Toxin Injections for Spastic Foot Treatment in Post-stroke Patients According to a Goal-centered ApproachRecruitingNot applicableHospices Civils de LyonNCT05874154Written as Botulinum toxin injection
- Essential Voice Tremor: A Study of Botulinum Toxin Treatment and Injection AugmentationCompletedNot applicableWeill Medical College of Cornell UniversityNCT02711995Written as Botulinum Toxin
- Efficacy Study of Selective Tibial Neurotomy in the Treatment of the Spastic Equinovarus Foot Among Adult Hemiplegic PatientsCompletedPhase 3Cliniques universitaires Saint-Luc- Université Catholique de LouvainNCT00825097Written as Botulinum toxin injection
What changed recently
From the registry's own updates since Oct 16, 2026.
Newly registered1
- Male Intimate Harmonization: Efficacy, Satisfaction, and SafetyOct 28, 2026NCT07901465
Codes
What other systems call Botulinum Toxins · ClinicalTrials.gg INT007085
- MeSH (NLM) D001905Botulinum ToxinsOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D001905 | Botulinum Toxins | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.