Cicatrix, Hypertrophic clinical trials
The registry lists 129 studies for Cicatrix, Hypertrophic across more than 10 countries. 31 are recruiting or about to start. 85 of them are mainly about Cicatrix, Hypertrophic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.
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Who runs them
Cairo University (10) · The Hong Kong Polytechnic University (3) · Pfizer (3) · Mahidol University (3) · Hangang Sacred Heart Hospital (3) · Massachusetts General Hospital (3) · Kaohsiung Veterans General Hospital. (2) · RXi Pharmaceuticals, Corp. (2)
What is being tested here
Drugs under test in Cicatrix, Hypertrophic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Triamcinolone Acetonide | 1 | 0 | 2 |
| Triamcinolone | 1 | 0 | 2 |
| ETD001 | 1 | 0 | 1 |
| Fluorouracil | 1 | 0 | 1 |
| Polidocanol | 1 | 0 | 1 |
| Remimazolam besilate | 1 | 0 | 1 |
| Remimazolam | 1 | 0 | 1 |
| Propofol | 1 | 0 | 1 |
| Bimatoprost | 1 | 0 | 1 |
| Botulinum toxin type A | 0 | 1 | 4 |
Drug classes tested here Corticosteroids 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization · Phase 3 · Henry Ford Health System
- Jun 2027Topical Cryotherapy and Keloid/Hypertrophic Scars · Phase 3 · Sonal Choudhary
- Nov 2026Efficacy in Preventing Hypertrophic Scars: A Randomised Controlled Trial Comparing Chitosan Cream, Silicone Gel & Olive Oil · Universiti Sains Malaysia
- Dec 2026Hypertrophic Scar Prosthetic Pressure in Burn Amputee · Centre hospitalier de l'Université de Montréal (CHUM)
- Jan 2027Remimazolam vs Propofol in Laser Burn Cases · Medical University of South Carolina
- Jan 2027Differential Pressure Distribution Orthosis by 3D Printing Process in the Treatment of Post-burn Hypertrophic Scarring · Centre Hospitalier Régional Metz-Thionville
- Apr 2027Surgical Care And Recovery With Laser Evaluation Trial (SCARLET) · AdventHealth
- Jun 2027Nano-Fat Grafting for Post-Burn Scars on the Chest, Shoulders, and Back · Assiut University
- Jun 2027Cost-Effectiveness of ESWT Plus Rehabilitation vs Rehabilitation Alone in Post-Burn Scars · Al Hayah University In Cairo
- Jul 2027Carbon Dioxide Laser-Assisted Delivery of Triamcinolone With or Without 5-Fluorouracil for Hypertrophic Burn Scars · University of California, Davis
Who these studies take
Of the 19 Cicatrix, Hypertrophic studies recruiting now, 8 (42%) set no upper age limit and 10 (53%) stop at 75 or younger. 1 (5%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (26%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (5%) | 1 (5%) |
| 18 | 17 (89%) | 17 (89%) |
| 30 | 19 (100%) | 19 (100%) |
| 40 | 19 (100%) | 19 (100%) |
| 50 | 18 (95%) | 18 (95%) |
| 65 | 15 (79%) | 15 (79%) |
| 75 | 10 (53%) | 10 (53%) |
| 85 | 9 (47%) | 9 (47%) |
Across all 129 studies, recruiting or not: 57% stop at 75 or younger and 47% at 65; 17% take children; 7% are for women only and 1% for men only; 31% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Cicatrix, Hypertrophic studies take
Of 33 interventional studies with no phase under Cicatrix, Hypertrophic, half reached primary completion within 18 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 18 mo12–30 · 33 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 129. Browse all 129 → or search them.
- Hypertrophic Scar Prosthetic Pressure in Burn AmputeeNot yet recruitingNCT078505571 country
- Phase II Clinical Study on Preliminary Efficacy and Safety of ETD-001 Gel for Hypertrophic ScarsNot yet recruitingNCT07891416Phase 21 country
- Umbilical Cord Stem Cells for Skin Grafts in Donor Site WoundsRecruitingNCT05984628Not applicable1 country
- Zinc Oxide Versus Petrolatum Following Skin SurgeryRecruitingNCT03561376Early Phase 11 country
- Carbon Dioxide Laser-Assisted Delivery of Triamcinolone With or Without 5-Fluorouracil for Hypertrophic Burn ScarsNot yet recruitingNCT07660120Not applicable
- Scar Gel Product Family Clinical InvestigationNot yet recruitingNCT07684573
- Differential Pressure Distribution Orthosis by 3D Printing Process in the Treatment of Post-burn Hypertrophic ScarringRecruitingNCT06487910Not applicable1 country
- Topical Cryotherapy and Keloid/Hypertrophic ScarsRecruitingNCT07336368Phase 31 country
- A Self-Controlled Clinical Study of Fast-Absorbable Versus Slow-Absorbable Sutures Applied in Ultra Tension-Reducing Suture TechniqueRecruitingNCT07639372Not applicable1 country
- Polidocanol 1% and Steroid in Keloids and Hypertrophic ScarsNot yet recruitingNCT07606391Not applicable1 country
- Nano-Fat Grafting for Post-Burn Scars on the Chest, Shoulders, and BackNot yet recruitingNCT07557472Not applicable
- Preoperative Silicone Ointment and Wound HealingEnrolling by invitationNCT05461157Not applicable1 country
- Surgical Care And Recovery With Laser Evaluation Trial (SCARLET)Not yet recruitingNCT07359352Not applicable
- Efficacy in Preventing Hypertrophic Scars: A Randomised Controlled Trial Comparing Chitosan Cream, Silicone Gel & Olive OilRecruitingNCT07269093Not applicable1 country
- Remimazolam vs Propofol in Laser Burn CasesRecruitingNCT07213544Phase 41 country
- Evaluation of Clinical, Perceived and Instrumental Efficacy of a Scar Gel in Preventing Hypertrophic ScarsRecruitingNCT06751433Phase 1/21 country
- Cost-Effectiveness of ESWT Plus Rehabilitation vs Rehabilitation Alone in Post-Burn ScarsRecruitingNCT06913257Not applicable1 country
- Silicone Taping for the Improvement of Abdominal Donor Site ScarsRecruitingNCT04506255Not applicable1 country
- Measuring the Volumes of Hypertrophic Scars and Keloids, Two Specific Kind of Scars, Over Different Points in Time in Patients Who Have Undergone Surgery and Evaluate 3D-cameras As a Possible Measuring and Documenting Tool Including VolumetryRecruitingNCT068067351 country
- Pulsed High Intensity Laser Versus Extracorporeal Shockwave Therapy on Hypertrophic Scar Post BurnNot yet recruitingNCT06803472Not applicable
- Microporous Tape and Post Surgical ScarsNot yet recruitingNCT06768047Not applicable
- Intralesional Treatment of KeloidsRecruitingNCT06729840Phase 31 country
- Effect of PRF & Fractional CO2 Laser in Postburn Hypertrophic ScarsNot yet recruitingNCT06664268Early Phase 1
- Electromotive Drug Administration of Magnesium Sulphate on Hypertrophic ScarNot yet recruitingNCT06649188Not applicable1 country
- Effectiveness of Dry Needling in Linear Scar TissueRecruitingNCT06033430Not applicable2 countries
- Clinical Utility of ESWT in Restoring Hand Function of Patients With Nerve Injury and Hypertrophic Scars Due to BurnsRecruitingNCT06438224Not applicable1 country
- Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald BurnsRecruitingNCT06104540Not applicable1 country
- Treatment of Hypopigmented Scars With BimatoprostRecruitingNCT06122090Phase 21 country
- Clinical Investigation to Evaluate the Performance of Hyaluronic Acid for the Treatment of Hypertrophic ScarsRecruitingNCT04614415Not applicable1 country
- Botulinum Toxin Type a Iontophoresis for Postburn Hypertrophic ScarRecruitingNCT05771623Not applicable1 country
- Web Based Investigation of Natural History of Keloid Disorder, an Online SurveyRecruitingNCT014239811 country
- An Innovative Image-Based Method for Extensibility AssessmentCompletedNCT06940999Not applicable1 country
- Study to Assess Efficacy and Safety of Dupilumab in the Treatment of KeloidsCompletedNCT05128383Phase 21 country
- Evaluating the Efficacy of Force Modulating Tissue Bridge Device in Preventing Hypertrophic Scars Following Gender-Affirming MastectomyTerminatedNCT07147166Not applicable1 country
- Safety, Tolerability, Pharmacokinetics, Immunogenicity and Efficacy of STP705 in Adult Patients With Hypertrophic ScarsWithdrawnNCT05196373Phase 1/21 country
- Safety, Tolerability and Efficacy of Nefopam Cream in Burn PatientsCompletedNCT04685577Phase 21 country
- Microneedling vs. 5-Fluorouracil or Steroid Injections for Hypertrophic Scars and KeloidsCompletedNCT07718269Phase 41 country
- A Study to Evaluate the Safety, Tolerability and Efficacy of AK3280 Cream on Hypertrophic ScarCompletedNCT05434897Phase 1/21 country
- Randomized Control Trial of CO2 Laser to Treat Hypertrophic Burn ScarCompletedNCT03692273Not applicable1 country
- Treatment of Hypertrophic Scars Using Fractional CO2 Laser Alone in Comparison With Adding Botulinum Toxin Either Through Intralesional Injection or Assisted Drug DeliveryCompletedNCT07360483Not applicable1 country
- Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar MinimizationActive, not recruitingNCT05478551Phase 2/31 country
- Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 LaserWithdrawnNCT04364217Not applicable1 country
- Comparative Study Between Intralesional Corticosteroid Injection Alone and Combined Intralesional Corticosteroid Injection With Either Long-pluse Nd YAG or Erbium Yag for Treating Hypertrophic or Keloid ScarsCompletedNCT07263100Not applicable1 country
- COMPARISON STUY OF KINESIOTAPE AND LOW-LEVEL LASER THERAPY ON HYPERTROPHIC SCARCompletedNCT07209891Not applicable1 country
- Topical Heparin for Prevention of Hypertrophic Scarring in Split-Thickness Skin Graft Donor SitesCompletedNCT07196358Not applicable1 country
- The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar FormationCompletedNCT03887377Phase 2/31 country
- Silicone vs Pirfenidone in the Treatment of Hypertrophic Scars and KeloidsCompletedNCT06909812Phase 31 country
- Intra-lesional ACE Inhibitor for Treatment of Hypertrophic ScarsWithdrawnNCT05259137Phase 2/3
- The Effect of Amniotic Membrane Application on Post-Cesarean Wound Healing and Cosmetic OutcomesCompletedNCT06770946Not applicable1 country
- Treatment of Fibrotic Scars With Rapid Acoustic Pulse (RAP) DeviceCompletedNCT04702529Not applicable1 country