Our grouping. This page groups the registry's lead sponsor names by company — our grouping, not the registry's. It can be wrong or incomplete: an acquired company whose name never mentions its owner may be missing. Use “Something wrong?” under any name below to correct it.
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PharmaMar clinical trials
Also known as Zeltia.
The registry lists 67 studies whose lead sponsor is PharmaMar or one of 3 companies grouped under it. 5 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 21, 2026.
Keep track of what changes. Save the PharmaMar studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesRegistry sponsor names on this page
Each name exactly as ClinicalTrials.gov lists it, and how it relates to PharmaMar.
- PharmaMar50 studiesSame company
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- Sylentis, S.A.12 studies →Subsidiary
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- Noscira SA3 studies →Subsidiary
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- PharmaMar, Spain2 studies →Regional office
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Focus areas
Conditions PharmaMar leads ten or more studies in, by study count. A broader condition is left out when almost all its studies are already in a narrower one listed here.
Studies
Recruiting first, then most recently updated. Showing 50 of 67. Browse all 67 →
- Study of PM54 in Combination With Immunotherapy in Adult Participants With Advanced MalignanciesRecruitingNCT07644039Phase 1/2
- Study of PM54 in Combination With Cytotoxic and Targeted Agents in Adult Participants With Advanced MalignanciesNot yet recruitingNCT07839819Phase 1/2
- Clinical Trial of PM54 in Advanced Solid Tumors Patients.RecruitingNCT05841563Phase 1
- PM534 Administered Intravenously to Patients With Advanced Solid TumorsRecruitingNCT05835609Phase 1
- Clinical Pharmacokinetic Study of Lurbinectedin in Patients With Advanced Solid Tumors and Varying Degrees of Hepatic ImpairmentRecruitingNCT05101265Phase 1
- Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)CompletedNCT05153239Phase 3
- Safety Study of Tivanisiran to Treat Dry EyeCompletedNCT05310422Phase 3
Sponsor listed in the registry: Sylentis, S.A.
- Study of Lurbinectedin in Combination With Doxorubicin Versus Doxorubicin Alone as First-line Treatment in Participants With Metastatic Leiomyosarcoma (SaLuDo)Active, not recruitingNCT06088290Phase 3
- PM14 Administered Intravenously to Patients With Advanced Solid TumorsCompletedNCT05076396Phase 1
- A Randomized, Double Masked, Parallel Group, Dose-finding Study to Evaluate SYL1801 in Patients With Neovascular Age-related Macular Degeneration (AMD)CompletedNCT05637255Phase 2
Sponsor listed in the registry: Sylentis, S.A.
- Study to Evaluate the Effect of Bosentan on the Pharmacokinetics of Lurbinectedin in Patients With Advanced Solid TumorsCompletedNCT05072106Phase 1
- Clinical Trial of Lurbinectedin (PM01183) in Patients With Advanced Solid TumorsCompletedNCT05063318Phase 1
- Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid TumorsCompletedNCT02611024Phase 1/2
- Trial to Determine the Efficacy/Safety of Plitidepsin vs Control in Patients With Moderate COVID-19 InfectionTerminatedNCT04784559Phase 3
- Extension Study in a Cohort of Adult Patients With COVID-19 InfectionCompletedNCT05121740Phase 1/2
- Plitidepsin Versus Control in Immunocompromised Adult Participants With Symptomatic COVID-19 Requiring Hospital Care (NEREIDA)TerminatedNCT05705167Phase 2
- Tivanisiran for Dry Eye in Subjects With Sjögren's SyndromeCompletedNCT04819269Phase 3
Sponsor listed in the registry: Sylentis, S.A.
- Efficacy and Safety of Trabectedin (Yondelis®) in Patients With Advanced Soft Tissue SarcomaCompletedNCT02367924
Sponsor listed in the registry: PharmaMar, Spain
- Clinical Trial of Lurbinectedin (PM01183) in Selected Advanced Solid TumorsCompletedNCT02454972Phase 2
- Proof of Concept Study to Evaluate the Safety Profile of Plitidepsin in Patients With COVID-19CompletedNCT04382066Phase 1
- Safety, Tolerability and Pharmacokinetic Profile of SYL1801 Eye DropsCompletedNCT04782271Phase 1
Sponsor listed in the registry: Sylentis, S.A.
- Non-interventional European Study of Trabectedin + PLD in the Treatment of Relapsed Ovarian Cancer (ROC) PatientsCompletedNCT02825420
- Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of ChemotherapyCompletedNCT01222767Phase 2
- Clinical Trial of PM00104 (Zalypsis®) in Patients With Advanced and/or Metastatic Endometrial or Cervical Cancer Previously Treated With One Line of Systemic ChemotherapyTerminatedNCT00900562Phase 2
- Clinical Trial of Lurbinectedin (PM01183)/Doxorubicin Versus CAV or Topotecan as Treatment in Patients With Small-Cell Lung CancerCompletedNCT02566993Phase 3
- A Phase I Study of Zalypsis (PM00104) in Subjects With Advanced Malignant Solid Tumors or LymphomaTerminatedNCT00359294Phase 1
- Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM060184 in Combination With Gemcitabine in Selected Patients With Advanced Solid TumorsCompletedNCT02533674Phase 1
- Clinical Trial of PM60184 in Advanced Colorectal Cancer After Standard TreatmentCompletedNCT03427268Phase 2
- SYL040012, Treatment for Open Angle GlaucomaCompletedNCT02250612Phase 2
Sponsor listed in the registry: Sylentis, S.A.
- Trial of Plitidepsin (Aplidin®) in Combination With Bortezomib and Dexamethasone in Multiple Myeloma Patients Double Refractory to Bortezomib and LenalidomideTerminatedNCT03117361Phase 2
- A Study of Aplidin ( Plitidepsin) in Subjects With Advanced Prostate CancerTerminatedNCT00780975Phase 2
- Aplidin - Dexamethasone in Relapsed/Refractory MyelomaCompletedNCT01102426Phase 3
- A Study of Plitidepsin in Patients With Relapsed or Refractory Angioimmunoblastic T-cell LymphomaTerminatedNCT03070964Phase 2
- Study of Plitidepsin (Aplidin®) in Combination With Bortezomib and Dexamethasone in Patients With Multiple MyelomaCompletedNCT02100657Phase 1
- Clinical Trial of Aplidin® in Patients With Primary MyelofibrosisCompletedNCT01149681Phase 2
- A Phase II Clinical Trial of PM01183 in BRCA 1/2-Associated or Unselected Metastatic Breast CancerCompletedNCT01525589Phase 2
- Phase I Study of Lurbinectedin (PM01183) in Combination With Paclitaxel, With or Without Bevacizumab, in Selected Advanced Solid TumorsCompletedNCT01831089Phase 1
- Clinical Trial of Lurbinectedin (PM01183) in Platinum Resistant Ovarian Cancer PatientsCompletedNCT02421588Phase 3
- Study Escalating Doses of PM01183 in Combination With Fixed Doxorubicin in Patients With Specific Advanced Unresectable Solid TumorsCompletedNCT01970540Phase 1
- Evaluation of the Effect of Lurbinectedin (PM01183) on Cardiac Repolarization in Patients With Selected Solid TumorsCompletedNCT02451007Phase 2
- A Clinical Study in Three-arm of Lurbinectedin (PM01183) Alone or in Combination With Gemcitabine and a Control Arm With Docetaxel as Second Line Treatment in Non-Small Cell Lung Cancer (NSCLC) PatientsCompletedNCT01951157Phase 2
- HELIX, a Double-masked Study of SYL1001 in Patients With Moderate to Severe Dry Eye Disease (DED)CompletedNCT03108664Phase 3
Sponsor listed in the registry: Sylentis, S.A.
- Clinical Study of Plitidepsin (Aplidin®) in Combination With Cytarabine in Patients With Relapsed/Refractory LeukemiaTerminatedNCT00780143Phase 1/2
- Multicenter Trial to Treat Patients With Relapsed/Refractory Aggressive Non Hodgkin LymphomaCompletedNCT00884286Phase 2
- An Observational Study of YONDELIS®+PLD for the Treatment of Patients With Platinum-sensitive Relapse of Ovarian CancerCompletedNCT01869400
Sponsor listed in the registry: PharmaMar, Spain
- Study of Lurbinectedin (PM01183) in Combination With Cisplatin in Patients With Solid TumorsCompletedNCT01980667Phase 1
- Study in Patients With Advanced Soft Tissue Sarcoma (STS) After Failure of Anthracyclines and/or IfosfamideCompletedNCT01299506
- Study of Lurbinectedin (PM01183) in Combination With Capecitabine in Patients With Metastatic Breast Cancer (MBC), Pancreatic Cancer (PC) or Metastatic Colorectal Cancer (CRC).CompletedNCT02210364Phase 1
- Dose-finding Study to Assess the Safety and Effect of SYL1001 in Patients With Ocular PainCompletedNCT02455999Phase 2
Sponsor listed in the registry: Sylentis, S.A.
- Study of PM01183 in Non-Colorectal Cancer Patients as a Days 1 and 8 Intravenous Short Infusion Every 3 WeeksCompletedNCT01405391Phase 1