Bosentan: all 86 studies that test it

Page 1 of 1. Open to participants first (4), then studies with results posted, then the rest; newest registration first within each.

• Bosentan in the Treatment of Giant Cell ArteritisNot yet recruitingNCT06957002Phase 2
• Dapagliflozin and Endothelin Receptor Antagonism in Large Vessel Vasculitis (DERAIL-LVV)RecruitingNCT06887062Phase 2
• Endothelin-1 Receptor Blockade in Resistant HypertensionRecruitingNCT04388124Phase 2
• ENDOTHELION Study Group: Effect of Bosentan in NAION PatientsRecruitingNCT02377271Phase 3
• A Study in Healthy Men to Test Whether Bosentan Influences the Amount of BI 425809 in the BloodCompletedNCT05723874Phase 1Results posted
• Study to Evaluate the Effect of Bosentan on the Pharmacokinetics of Lurbinectedin in Patients With Advanced Solid TumorsCompletedNCT05072106Phase 1Results posted
• Influence of Bosentan on the Pharmacokinetics of NintedanibCompletedNCT02667704Phase 1Results posted
• Bosentan and Pulmonary Endothelial FunctionCompletedNCT01721564Not applicableResults posted
• Pharmacokinetic Effects of QTI571 on Sildenafil and Bosentan in Pulmonary Arterial Hypertension ParticipantsCompletedNCT01392469Phase 3Results posted
• Persistent Pulmonary Hypertension of the NewbornTerminatedNCT01389856Phase 3Results posted
• FUTURE 3 Study ExtensionCompletedNCT01338415Phase 3Results posted
• Effects of Two Dosing Regimens of Bosentan in Children With Pulmonary Arterial HypertensionCompletedNCT01223352Phase 3Results posted
• Endothelin Blockade in Patients With Single Ventricle PhysiologyCompletedNCT00989911Not applicableResults posted
• Insulin Resistance in Pulmonary Arterial HypertensionTerminatedNCT00825266Phase 2Results posted
• Bosentan for Poorly Controlled AsthmaTerminatedNCT00815347Phase 2Results posted
• Open Label Extension Study in Patients With Idiopathic Pulmonary Fibrosis Who Completed Protocol AC-052-321/ BUILD 3 / NCT00391443CompletedNCT00631475Phase 3Results posted
• Combination Therapy in Pulmonary Arterial HypertensionCompletedNCT00433329Phase 4Results posted
• BUILD 3: Bosentan Use in Interstitial Lung DiseaseCompletedNCT00391443Phase 3Results posted
• Placebo Controlled Trial of Bosentan in Scleroderma PatientsTerminatedNCT00377455Phase 2Results posted
• BREATHE 5-OL: Tracleer (Bosentan) in Patients With Pulmonary Arterial Hypertension Related to Eisenmenger PhysiologyCompletedNCT00367770Phase 4Results posted
• Bosentan in Digital UlcersCompletedNCT00319696Phase 3Results posted
• Bosentan in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH)CompletedNCT00319111Phase 3Results posted
• Bosentan in Children With Pulmonary Arterial Hypertension Extension StudyCompletedNCT00319020Phase 3Results posted
• Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH)CompletedNCT00303459Phase 4Results posted
• A Study in Healthy Men to Test How Bosentan Influences the Amount of Zongertinib in the BloodCompletedNCT07649941Phase 1
• A Study in Healthy Men to Test How Bosentan Influences the Amount of Nerandomilast in the BloodCompletedNCT07081932Phase 1
• Bioequivalence Study to Compare Bosentan 32 mg Dispersible Tablets Versus Tracleer® 32 mg TabletsCompletedNCT06484673Phase 1
• Reflex Responses to Intermittent Hypoxia in Humans: Mechanisms and ConsequencesCompletedNCT05146089Early Phase 1
• Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of BosentanCompletedNCT04991207Phase 1
• Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic CancerSuspendedNCT04158635Phase 1
• Bioequivalence Study of Bosentan 125 mg Tablets Immediate Release (IR) Versus Tracleer® 125 mg Tablets IR In Healthy SubjectsCompletedNCT04101370Phase 1
• Safety of Bosentan in Type II Diabetic PatientsCompletedNCT04068272Phase 1
• the Effect of Tracleer on Tourniquet-associated HypertensionStatus unknownNCT03229694Phase 4
• The Clinical And Subclinical Effects on Arterial Stiffness of Bosentan in Patients With Systemic SclerosisCompletedNCT02480335Phase 4
• Treatment of Resistant Port-wine Stains With Bosentan and Pulsed Dye Laser: a Pilot StudyCompletedNCT02317679Phase 2
• Endothelin Receptor Function and Acute StressActive, not recruitingNCT02116335Not applicable
• Study of Bosentan in the Treatment of Stable Severe Chronic Obstructive Pulmonary Disease PatientsStatus unknownNCT02093195Phase 2
• Clinical Trial to Investigate the Pharmacokinetic Drug Interaction Between Udenafil and Bosentan After Oral AdministrationStatus unknownNCT01929213Phase 1
• To Compare the Pharmacokinetics of Traclear 62.5 mg Tablets and HGP1206 125mg 1 Tablet in Healthy Male VolunteersCompletedNCT01864863Phase 1
• Bosentan In Exercise Induced Pulmonary Arterial Hypertension in CongenitaL Heart diseasEStatus unknownNCT01827059Phase 2
• ET-blockade and Exercise-induced Vascular Adaptations in T2DMCompletedNCT01779609Phase 4
• ET-blockade and Exercise Induced Blood Flow in T2DMCompletedNCT01779596Phase 4
• Safety and Efficacy Study of Bosentan for Intermittent Claudication in Peripheral Arterial DiseaseCompletedNCT01738542Not applicable
• Bosentan Therapy in Children With Functional Single VentricleCompletedNCT01662037Phase 2
• Examination of the Bronchoprotective Effect of Endothelin Receptor Blockade in AsthmaStatus unknownNCT01617746Phase 2
• Bosentan for Treatment of Hepatopulmonary Syndrome in Patients With Liver CirrhosisTerminatedNCT01518595Phase 2
• Comparison of Efficacy Different Treatment Regimens in Pulmonary Hypertension Secondary to Lung Disease and or HypoxiaStatus unknownNCT01449253Phase 4
• Bosentan in Systemic SclerosisCompletedNCT01395732Phase 4
• Prognostic Influence of Light Rheography Measurement of Patients With Secondary Raynaud Syndrome With Ulcers on HandsStatus unknownNCT01378845Not applicable
• Effect of Bosentan on Endothelial Function in Patients With Type 2 DiabetesCompletedNCT01357109Phase 2
• Characterization and Detection of Prolonged Endothelin Receptors Antagonists AdministrationCompletedNCT01352065Phase 2/3
• Study of Placebo or Bosentan to Treat Patients With Single Ventricle Physiology.CompletedNCT01292551Phase 2
• Bosentan for Severe Mitral Valve DysfunctionStatus unknownNCT01270750Phase 1/2
• Effect of Bosentan in Scleroderma Renal CrisisCompletedNCT01241383Phase 2
• Bosentan for Mild Pulmonary Vascular Disease in Asd Patients.CompletedNCT01218607Phase 3
• Bosentan Improves Clinical Outcome of Adults With Congenital Heart Disease or Mitral Valve Lesions Who Undergo CArdiac SurgeryStatus unknownNCT01184404Not applicable
• Effect of Bosentan in Patients With Metastatic Melanoma Treated With Dacarbazine (DTIC)CompletedNCT01009177Phase 2
• Safety and Efficacy Study of Bosentan in Progressive Pulmonary SarcoidosisTerminatedNCT00926627Phase 2
• Early Therapy of Pulmonary Arterial HypertensionCompletedNCT00909337Not applicable
• A Study to Evaluate the Use of Bosentan in Patients With Exercise Induced Pulmonary Arterial Hypertension Associated With Connective Tissue DiseaseStatus unknownNCT00864201Phase 3
• Safety and Efficacy of Bosentan in Patients With Diastolic Heart Failure and Secondary Pulmonary HypertensionCompletedNCT00820352Phase 3
• Preventive Effects of Bosentan on the Systemic Cardiovascular Consequence of Sleep ApneaCompletedNCT00777985Phase 2
• Effects of Non-Specific Endothelin-A Receptor Blockade on Ocular Blood Flow in Patients With GlaucomaCompletedNCT00701597Phase 1
• Effects of Bosentan on Respiratory MechanicsTerminatedNCT00679068Phase 4
• Bosentan Use in Patients With Diabetic NephropathyTerminatedNCT00638131Phase 3
• Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment StudyStatus unknownNCT00637065Phase 4
• Pulmonary Arterial Hypertension Secondary to Idiopathic Pulmonary Fibrosis and Treatment With BosentanWithdrawnNCT00625469Phase 4
• Pulmonary Artery Remodelling With BosentanCompletedNCT00595049Phase 4
• Double Blind, Randomized Trial of Bosentan for Sarcoidosis Associated Pulmonary HypertensionCompletedNCT00581607Phase 2/3
• A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET StudyTerminatedNCT00360087Phase 3
• Bosentan in Children With Pulmonary Arterial HypertensionCompletedNCT00319267Phase 3
• Open-label Study With Bosentan in Interstitial Lung DiseaseCompletedNCT00319033Phase 2/3
• Effect of Bosentan on Skin Fibrosis in Patients With Systemic SclerosisCompletedNCT00318175Phase 2
• Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger PhysiologyCompletedNCT00317486Phase 4
• Bosentan Effects in Inoperable Forms of Chronic Thromboembolic Pulmonary HypertensionCompletedNCT00313222Phase 3
• Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients Diagnosed With Pulmonary Hypertension (PH)TerminatedNCT00313196Phase 3
• Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients With Pulmonary Arterial Hypertension (PAH)TerminatedNCT00310830Phase 3
• Combination Treatment With Bosentan and Sildenafil to Patients With Eisenmengers SyndromeCompletedNCT00303004Phase 3
• Effects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by HypoxiaCompletedNCT00260819Phase 1
• Treatment of Early Systemic Sclerosis by BosentanTerminatedNCT00226889Phase 1/2
• Treatment of Supine Hypertension in Autonomic FailureCompletedNCT00223717Phase 1
• Efficacy and Safety of Oral Bosentan in Pulmonary Arterial Hypertension Class IICompletedNCT00091715Phase 3
• The Effect of Tracleer® on Male FertilityCompletedNCT00082186Phase 4
• Efficacy and Safety of Oral Bosentan on Healing/Prevention of Digital (Finger) Ulcers in Patients With SclerodermaCompletedNCT00077584Phase 3
• Efficacy and Safety of Oral Bosentan in Patients With Idiopathic Pulmonary FibrosisCompletedNCT00071461Phase 2/3
• Efficacy and Safety of Oral Bosentan in Pulmonary Fibrosis Associated With SclerodermaCompletedNCT00070590Phase 2/3

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