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Wilms Tumor clinical trials

The registry lists 200 studies for Wilms Tumor across more than 10 countries. 25 are recruiting or about to start. 44 of them are mainly about Wilms Tumor (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04.

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Status

Completed
122
Recruiting
23
Active, not recruiting
16
Status unknown
15
Terminated
13
Withdrawn
8

Phase

Phase 1
72
Phase 2
67
Phase 3
20
Phase 4
2
Early Phase 1
1

Where

United States
157
Canada
23
Puerto Rico
22
Australia
21
New Zealand
10
France
9

Who runs them

National Cancer Institute (NCI) (31) · Children's Oncology Group (29) · Fred Hutchinson Cancer Center (10) · Memorial Sloan Kettering Cancer Center (8) · St. Jude Children's Research Hospital (6) · M.D. Anderson Cancer Center (5) · National Institutes of Health Clinical Center (CC) (4) · Emory University (4)

What is being tested here

Drugs under test in Wilms Tumor studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Doxorubicin2511
Vincristine2511
Temozolomide206
Irinotecan204
Etoposide1310
Ifosfamide106
Topotecan103
Cabozantinib102
Liposomal doxorubicin102
Vorinostat102

Drug classes tested here Alkylating agents 3 open · Antimitotic agents 2 open · Tyrosine kinase inhibitors (TKIs) 1 open · PARP inhibitors 1 open · Immune checkpoint inhibitors 1 open

Coming up

1phase 3 study under way
12studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest

Who these studies take

Of the 23 Wilms Tumor studies recruiting now, 3 (13%) set no upper age limit and 19 (83%) stop at 75 or younger. 22 (96%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (4%) take healthy volunteers.

Recruiting studies that take each age, of 23
AgeWomenMen
1021 (91%)21 (91%)
1822 (96%)22 (96%)
3012 (52%)12 (52%)
405 (22%)5 (22%)
504 (17%)4 (17%)
654 (17%)4 (17%)
754 (17%)4 (17%)
854 (17%)4 (17%)

Across all 200 studies, recruiting or not: 73% stop at 75 or younger and 71% at 65; 91% take children; 0% are for women only and 1% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Wilms Tumor studies take

Of 23 phase 1 interventional studies under Wilms Tumor, half reached primary completion within 70 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 170 mo57–134 · 23 studies——
Phase 263 mo49–81 · 22 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

Studies

Recruiting first, then most recently updated. Showing 50 of 200. Browse all 200 → or search them.