Drug
Vorinostat clinical trials
Also written Zolinza, Suberoylanilide Hydroxamic Acid, MSK-390 and MK-0683.
- studies test it
- 244
- open now
- 9
- in phase 3
- 7
- first study started
- 2000
Keep track of what changes. Save the Vorinostat studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
242 studies that test it; most in 2009 (35)
| Year | Studies |
|---|---|
| 2000 | 1 |
| 2001 | 1 |
| 2003 | 1 |
| 2004 | 2 |
| 2005 | 26 |
| 2006 | 22 |
| 2007 | 17 |
| 2008 | 23 |
| 2009 | 35 |
| 2010 | 25 |
| 2011 | 14 |
| 2012 | 16 |
| 2013 | 8 |
| 2014 | 8 |
| 2015 | 6 |
| 2016 | 6 |
| 2017 | 9 |
| 2018 | 3 |
| 2019 | 3 |
| 2020 | 4 |
| 2021 | 2 |
| 2023 | 1 |
| 2024 | 2 |
| 2025 | 3 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 152
- Phase 2
- 136
- Phase 3
- 7
- No phase
- 5
What it is tested for
Each study’s main condition, where its own words name it.
- Lymphoma
- 18
Who runs them
Industry 28 · Other 216
National Cancer Institute (NCI) (60) · Merck Sharp & Dohme LLC (26) · M.D. Anderson Cancer Center (16) · University of Washington (6) · City of Hope Medical Center (5) · Fred Hutchinson Cancer Center (5) · Masonic Cancer Center, University of Minnesota (5) · H. Lee Moffitt Cancer Center and Research Institute (4)
Often tested with
Tested in the same studies.
Bortezomib (25) · Dexamethasone (9) · Decitabine (9) · Gemcitabine (9) · Lenalidomide (8) · Doxorubicin (8) · Temozolomide (7) · Cytarabine (7)
Studies
Open first, then newest update. How each study uses Vorinostat is read from its arms, and is right about nine times in ten.
Testing it · 244
- Vorinostat for Graft-versus-host Disease (GVHD) Prevention in Non-Malignant Adolescent and Young Adults (AYA) PopulationRecruitingPhase 2Sung Won ChoiNCT06995521Written as Vorinostat
- An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With UstekinumabRecruitingPhase 1/2National Institute of Allergy and Infectious Diseases (NIAID)NCT03167437Written as Vorinostat
- Rett REVOLUTION Trial: An Exploratory Evaluation of the Safety and Efficacy of Vorinostat in Rett SyndromeRecruitingPhase 1Unravel Biosciences, Inc.NCT07150013Written as Vorinostat (SAHA)
- An Exploratory Evaluation of the Safety and Efficacy of Vorinostat in Pitt Hopkins SyndromeRecruitingPhase 1Unravel Biosciences, Inc.NCT07150026Written as Vorinostat (SAHA)
- NANT 2021-02: Randomized MIBG With Vorinostat/Dinutuximab/Vorinostat + DinutuximabNot yet recruitingPhase 2New Approaches to Neuroblastoma Therapy ConsortiumNCT07261241Written as Vorinostat
- Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate CancerRecruitingPhase 2Fred Hutchinson Cancer CenterNCT06145633Written as Vorinostat
- TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia IIRecruitingPhase 1/2Tanja Andrea GruberNCT05848687Written as Vorinostat
- A Window of Opportunity Trial of Mirdametinib Plus Vorinostat for NF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST]RecruitingEarly Phase 1University of MinnesotaNCT06693284Written as mirdametinib and vorinostat
- Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS MalignanciesRecruitingPhase 1New York Medical CollegeNCT04308330Written as Vorinostat
- Vorinostat, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Diffuse Large B-Cell LymphomaActive, not recruitingPhase 1/2National Cancer Institute (NCI)NCT00972478Written as Vorinostat
- Pembro and Vorinostat for Patients With Stage IV Non-small Cell Lung Cancer (NSCLC)Active, not recruitingPhase 1/2H. Lee Moffitt Cancer Center and Research InstituteNCT02638090Written as Vorinostat
- Vorinostat in Combination With Vinorelbine in Patients With Advanced CancerTerminatedPhase 1Institut Claudius RegaudNCT00801151Written as Zolinza (vorinostat), vinorelbine
- Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic LeukemiaActive, not recruitingPhase 2National Cancer Institute (NCI)NCT01522976Written as Vorinostat
- A Study of Carfilzomib, Lenalidomide, Vorinostat, and Dexamethasone in Relapsed and/or Refractory Multiple MyelomaActive, not recruitingPhase 1/2Hackensack Meridian HealthNCT01297764Written as Vorinostat, Lenalidomide, Carfilzomib, Dexamethasone
- Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL.Active, not recruitingPhase 1City of Hope Medical CenterNCT03150329Written as Vorinostat
- Vorinostat and Temozolomide in Treating Patients With Malignant GliomasActive, not recruitingPhase 1National Cancer Institute (NCI)NCT00268385Written as Vorinostat
- Vorinostat and Azacitidine in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer or Nasal Natural Killer T-Cell LymphomaActive, not recruitingPhase 1National Cancer Institute (NCI)NCT00336063Written as Vorinostat
- Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid LeukemiaActive, not recruitingPhase 1/2National Cancer Institute (NCI)NCT00392353Written as Vorinostat
- Vorinostat in Treating Patients With Metastatic Melanoma of the EyeActive, not recruitingPhase 2National Cancer Institute (NCI)NCT01587352Written as Vorinostat
- Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell TransplantationActive, not recruitingPhase 1Johns Hopkins All Children's HospitalNCT03843528Written as Vorinostat
See all 244 studies that test Vorinostat →
Given in every arm · 15 — Vorinostat is usual care beside what is tested
- Pediatric Precision Laboratory Advanced Neuroblastoma TherapyRecruitingPhase 2Giselle ShollerNCT02559778Written as vorinostat
- Venetoclax to Augment Epigenetic Modification and ChemotherapyRecruitingPhase 1Medical College of WisconsinNCT05317403Written as Vorinostat
- High-Dose or Low-Dose Vorinostat in Combination With Carboplatin or Paclitaxel in Treating Patients With Advanced Solid TumorsActive, not recruitingPhase 1National Cancer Institute (NCI)NCT01281176Written as Vorinostat
- The DART DELIVER-02 StudySuspendedPhase 1University of North Carolina, Chapel HillNCT07217379Written as Vorinostat
- Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell TransplantCompletedPhase 1M.D. Anderson Cancer CenterNCT03259503Written as Vorinostat
- Sirolimus or Everolimus or Temsirolimus and Vorinostat in Advanced CancerActive, not recruitingPhase 1M.D. Anderson Cancer CenterNCT01087554Written as Vorinostat
- Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine GliomaCompletedPhase 1M.D. Anderson Cancer CenterNCT02420613Written as Vorinostat
- Selective Estrogen Receptor Modulators to Enhance the Efficacy of Viral Reactivation With Histone Deacetylase InhibitorsCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT03382834Written as Vorinostat
- Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)TerminatedPhase 1/2M.D. Anderson Cancer CenterNCT01110876Written as Vorinostat
- Phase I Vorinostat in Combination With Niacinamide and Etoposide for Lymphoid MalignanciesCompletedPhase 1Columbia UniversityNCT00691210Written as Vorinostat
- Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV InfectionTerminatedPhase 1AIDS Malignancy ConsortiumNCT01249443Written as vorinostat
- Reversing Therapy Resistance With Epigenetic-Immune ModificationTerminatedPhase 2University of California, San FranciscoNCT02395627Written as Vorinostat
- Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic MalignanciesTerminatedPhase 2St. Jude Children's Research HospitalNCT02419755Written as Vorinostat
- Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or LeukemiaCompletedPhase 1National Cancer Institute (NCI)NCT00217412Written as vorinostat
- Vorinostat and Bortezomib in Treating Patients With Progressive, Recurrent Glioblastoma MultiformeCompletedPhase 2National Cancer Institute (NCI)NCT00641706Written as vorinostat
As the comparator · 3 — what is tested is compared with Vorinostat
- Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein in Subjects With Mycosis FungoidesWithdrawnPhase 2Virogen Biotechnology Inc.NCT02943642Written as Vorinostat
- Study of KW-0761 Versus Vorinostat in Relapsed/Refractory CTCLCompletedPhase 3Kyowa Kirin, Inc.NCT01728805Written as Vorinostat
- SOLAR: Efficacy and Safety of Cobomarsen (MRG-106) vs. Active Comparator in Subjects With Mycosis FungoidesTerminatedPhase 2miRagen Therapeutics, Inc.NCT03713320Written as Vorinostat
Codes
What other systems call Vorinostat · ClinicalTrials.gg INT006704
- MeSH (NLM) D000077337VorinostatConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 58IFB293JIVORINOSTATConfirmed FDA, NLM, Wikidata
- RxNorm 194337Confirmed FDA, Wikidata
- Wikidata Q905901vorinostatConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C1796VorinostatOne source FDA
- DrugBank DB02546One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077337 | Vorinostat | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 58IFB293JI | VORINOSTAT | Confirmed FDA, NLM, Wikidata |
| RxNorm | 194337 | — | Confirmed FDA, Wikidata |
| Wikidata | Q905901 | vorinostat | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C1796 | Vorinostat | One source FDA |
| DrugBank | DB02546 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.