Kidney Neoplasms clinical trials
The registry lists 969 studies for Kidney Neoplasms across more than 10 countries. 210 are recruiting or about to start. 279 of them are mainly about Kidney Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 3 narrower conditions too, such as Carcinoma, Renal Cell: 2,691 studies, 556 open.
ClinicalTrials.gov finds 3,348 studies for Kidney Neoplasms. How that becomes 968 here
This page counts the studies the registry files under Kidney Neoplasms, and those it files under no condition that list Kidney Neoplasmsthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 3,348Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −1,662Filed under a narrower condition, counted on its own pageCarcinoma, Renal Cell 1,482 · Wilms Tumor 143 · Clear-cell metastatic renal cell carcinoma 10
- −5List Kidney Neoplasms as a condition, but the registry did not file them under itMost often written as “Recurrent Childhood Kidney Neoplasm” (1), “Childhood Kidney Neoplasm” (1), and “Clear Cell Renal Cancer” (1). The registry filed them under other conditions only, most often Hepatoblastoma (1) and Precursor Cell Lymphoblastic Leukemia-Lymphoma (1).
- −713Match it another way11 name it in the title, 5 in a keyword, and 697 by a synonym or other text the search reads.
- 968The count on this page11 of them list Kidney Neoplasms in their own words; the registry filed them under no condition.
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Who runs them
National Cancer Institute (NCI) (55) · Memorial Sloan Kettering Cancer Center (35) · Pfizer (21) · M.D. Anderson Cancer Center (21) · Children's Oncology Group (15) · Bristol-Myers Squibb (12) · National Institutes of Health Clinical Center (CC) (11) · Novartis Pharmaceuticals (10)
What is being tested here
Drugs under test in Kidney Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Pembrolizumab | 4 | 3 | 9 |
| Nivolumab | 3 | 3 | 17 |
| Axitinib | 3 | 4 | 12 |
| Ipilimumab | 3 | 3 | 11 |
| Cabozantinib | 3 | 1 | 6 |
| Fludarabine | 2 | 0 | 10 |
| Casdatifan | 2 | 1 | 3 |
| Lenvatinib | 2 | 1 | 3 |
| Lutetium (¹⁷⁷Lu) vipivotide tetraxetan | 2 | 1 | 3 |
| Gallium-68 | 2 | 0 | 2 |
Drug classes tested here Immune checkpoint inhibitors 13 open · Tyrosine kinase inhibitors (TKIs) 10 open · Antimetabolites 2 open · Alkylating agents 2 open · Angiogenesis inhibitors 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Aug 2027Phase 3 Study to Assess Safety and Efficacy of 177Lu-TLX250 in Advanced Relapsed or Recurrent ccRCC · Phase 3 · Telix Pharmaceuticals (Innovations) Pty Limited
- Oct 2027Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery · Phase 3 · Hans Bahlmann
- Nov 2026A Preregistered Multi-Cohort Evaluation of the FATHOM AI System for Molecular Testing Prioritization to Support Clinical Trial Enrollment · Harvard Medical School (HMS and HSDM)
- Nov 2026A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma · HiberCell, Inc.
- Nov 2026CD70-targeted immunoPET Imaging of Kidney Cancer · RenJi Hospital
- Nov 2026Neoadjuvant Pembrolizumab and Axitinib in Renal Cell Carcinoma With Inferior Vena Cava Tumor Thrombus · University of Colorado, Denver
- Dec 2026Perioperative Ursodeoxycholic Acid for Renal Protection in Adults Undergoing Partial Nephrectomy for Renal Tumors · Jinling Hospital, China
- Dec 2026Occupational Situation and Return to Work of Urological Patients · Jagiellonian University
- Dec 2026Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders · Memorial Sloan Kettering Cancer Center
- Dec 2026177LuPSMA in Renal Cell Carcinoma · Dana-Farber Cancer Institute
Who these studies take
Of the 173 Kidney Neoplasms studies recruiting now, 133 (77%) set no upper age limit and 15 (9%) stop at 75 or younger. 20 (12%) take children under 18. 1 (1%) are for women only and 2 (1%) for men only; 24 (14%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 18 (10%) | 18 (10%) |
| 18 | 162 (94%) | 163 (94%) |
| 30 | 165 (95%) | 166 (96%) |
| 40 | 166 (96%) | 167 (97%) |
| 50 | 167 (97%) | 168 (97%) |
| 65 | 169 (98%) | 170 (98%) |
| 75 | 165 (95%) | 166 (96%) |
| 85 | 143 (83%) | 144 (83%) |
Across all 969 studies, recruiting or not: 11% stop at 75 or younger and 5% at 65; 14% take children; <1% are for women only and 1% for men only; 5% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Kidney Neoplasms studies take
Of 74 phase 2 interventional studies under Kidney Neoplasms, half reached primary completion within 67 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 56 mo33–75 · 65 studies | 53 mo28–61 · 42 studies | — |
| Phase 1/2 | 66 mo61–91 · 31 studies | — | — |
| Phase 2 | 67 mo36–112 · 74 studies | — | 67 mo41–112 · 64 studies |
| Phase 3 | 70 mo35–89 · 22 studies | — | — |
| Interventional, no phase | 42 mo21–90 · 97 studies | — | 48 mo24–94 · 90 studies |
| Observational | 74 mo28–… · 107 studies | — | 74 mo34–… · 89 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
Results posted2
Newly registered6
- Lifileucel (TIL) Therapy After PD-1 Blockade Failure in Kidney CancerNov 9, 2026NCT07925333
- Prospective Study of Cadonilimab With Lenvatinib in Renal Cell CarcinomaNov 2, 2026NCT07909265
- Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and ProstateOct 22, 2026NCT07888322
- Effect of Non-Clamping and Sutureless Technique on Postoperative Renal Function in Robot-Assisted Partial NephrectomyOct 22, 2026NCT07888608
- Phase 2a Study to Assess Safety and Efficacy of Two 177Lu-TLX250 Dosing Regimens in Advanced Relapsed or Recurrent ccRCCOct 13, 2026NCT07870746
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- A Study of Treatment Delivery Preference In People With Kidney CancerOct 13, 2026NCT07872553
Studies
Recruiting first, then most recently updated. Showing 50 of 969. Browse all 969 → or search them.
- Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal CancerRecruitingNCT000507521 country
- A Phase 1b/2 Study of the Safety and Efficacy of the Monoclonal Antibody OM-RCA-01 in Patients With Metastatic Tumors Expressing Fibroblast Growth Factor Receptor 1RecruitingNCT07292168Phase 1/21 country
- Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant DiseaseRecruitingNCT000268841 country
- Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney CancerRecruitingNCT000331371 country
- Lifileucel (TIL) Therapy After PD-1 Blockade Failure in Kidney CancerNot yet recruitingNCT07925333Phase 21 country
- Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated ConditionsRecruitingNCT031602741 country
- A Study Comparing Single-Port and Multi-Port Robot-Assisted Surgery in Patients With Prostate or Kidney (Renal) CancerNot yet recruitingNCT076100831 country
- cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual DiseaseRecruitingNCT053668811 country
- Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant DisordersRecruitingNCT000012381 country
- Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell CarcinomaRecruitingNCT07300241Phase 11 country
- Distance-Based Exercise to Preserve Function and Prevent DisabilityRecruitingNCT07059884Not applicable1 country
- Prospective Study of Cadonilimab With Lenvatinib in Renal Cell CarcinomaRecruitingNCT07909265Phase 21 country
- Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell CarcinomaRecruitingNCT07011719Phase 317 countries
- A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid TumorsRecruitingNCT05536141Phase 14 countries
- Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and ProstateNot yet recruitingNCT078883224 countries
- Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment DisorderRecruitingNCT07072728Phase 21 country
- A Study of a Side Effects and Resource Navigation Program for People With CancerRecruitingNCT07646847Not applicable1 country
- Stereotactic Body RadioTherapy With Continuous Tracking for Primary and Secondary Renal CancerRecruitingNCT07285538Not applicable1 country
- Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell ManufacturingRecruitingNCT049811191 country
- Effect of Non-Clamping and Sutureless Technique on Postoperative Renal Function in Robot-Assisted Partial NephrectomyRecruitingNCT07888608Not applicable1 country
- Palbociclib and Sasanlimab for the Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Papillary Renal Cell Carcinoma (pRCC)RecruitingNCT05665361Phase 1/21 country
- A Study of Treatment Delivery Preference In People With Kidney CancerRecruitingNCT07872553Phase 41 country
- Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological StudiesRecruitingNCT011093941 country
- Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid TumorsRecruitingNCT06239194Phase 1/21 country
- Perioperative Ursodeoxycholic Acid for Renal Protection in Adults Undergoing Partial Nephrectomy for Renal TumorsRecruitingNCT07672860Phase 21 country
- Post-immunotherapy Nephrectomy for Metastatic Kidney Cancer After Complete or Major Response to Systemic TherapyRecruitingNCT06882486Not applicable1 country
- KO-2806 Monotherapy and Combination Therapies in Advanced Solid TumorsRecruitingNCT06026410Phase 15 countries
- Phase 2a Study to Assess Safety and Efficacy of Two 177Lu-TLX250 Dosing Regimens in Advanced Relapsed or Recurrent ccRCCNot yet recruitingNCT07870746Phase 21 country
- Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell CancerRecruitingNCT07227415Phase 1/26 countries
- Benchmarking Large Language Models Against Tumour Boards for Oncology Treatment RecommendationsRecruitingNCT077391211 country
- [212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck CancersRecruitingNCT06479811Phase 11 country
- A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell CarcinomaRecruitingNCT06234605Phase 11 country
- The Impact of Time-of-day-Dependent Administration of Nivolumab-Ipilimumab (ICI/ICI) Combination on Overall Survival in Adults With Advanced Kidney Cancer: A Pragmatic Multicenter, Randomized Controlled Trial.Not yet recruitingNCT07338981Phase 31 country
- Patient Reported Outcomes and Different Renal Artery Clamping Techniques During Robot Assisted Kidney ResectionNot yet recruitingNCT07853001Not applicable1 country
- HTL0039732 in Participants With Advanced Solid TumoursRecruitingNCT05944237Phase 1/21 country
- Study of Orellanine in Metastatic Clear-Cell or Papillary Renal Cell CarcinomaRecruitingNCT05287945Phase 1/25 countries
- The Application of 18F-G1 PET/CT Targeting Granzyme B in the Pan-cancer ImmunotherapyRecruitingNCT070394741 country
- A Phase 1b Study of HC-7366, an Agonist of ISR With Immunotherapy in Kidney Cancer (SHARK)RecruitingNCT07401875Phase 11 country
- QLESP Block for Pain Control in Robotic Partial NephrectomyRecruitingNCT07704970Not applicable1 country
- Liquid Biopsy Evaluation and Repository Development at Princess MargaretRecruitingNCT037023091 country
- Microwave Ablation for Treatment of Small Renal Tumors and Primary and Secondary Liver NeoplasmsRecruitingNCT039814971 country
- Deferred Cytoreductive Nephrectomy in Synchronous Metastatic Renal Cell Carcinoma: The NORDIC-SUN-TrialRecruitingNCT03977571Not applicable4 countries
- A Study of Theranostic Pair PD-32766D/T in Participants With Carbonic Anhydrase IX Positive Clear Cell Renal Cell CarcinomaRecruitingNCT07688187Phase 11 country
- Photodynamic Diagnosis of Upper Tract Urothelial Carcinoma Using Fluorescence Endoscopy and Oral 5-ALARecruitingNCT06948552Phase 21 country
- Photodynamic Diagnosis of Kidney Cancer Using Fluorescence Endoscopy and Oral 5-ALARecruitingNCT07828704Phase 21 country
- Development of a Preclinical 3D Vascularized and Perfused Tumoroid Model in Oncology and Urology Developed From Patient Tumors (Kidney, Bladder, and Prostate Cancers)RecruitingNCT078205661 country
- SL-28 for Advanced Solid TumoursRecruitingNCT07341737Phase 1/21 country
- A Preregistered Multi-Cohort Evaluation of the FATHOM AI System for Molecular Testing Prioritization to Support Clinical Trial EnrollmentNot yet recruitingNCT078148721 country
- Hyperspectral Imaging in Robot-Assisted Partial NephrectomyRecruitingNCT078033151 country
- Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer PatientsRecruitingNCT06138067Not applicable1 country