Urinary Bladder, Overactive clinical trials
The registry lists 858 studies for Urinary Bladder, Overactive across more than 10 countries. 127 are recruiting or about to start. 710 of them are mainly about Urinary Bladder, Overactive (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
ClinicalTrials.gov finds 945 studies for Urinary Bladder, Overactive. How that becomes 858 here
This page counts the studies the registry files under Urinary Bladder, Overactive, and those it files under no condition that list Urinary Bladder, Overactivethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 945Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −29List Urinary Bladder, Overactive as a condition, but the registry did not file them under itMost often written as “Overactive Bladder Syndrome” (22), “Urinary Retention and Symptoms of Overactive Bladder (Urge, Frequency)” (1), and “Overactive Bladder With Symptoms of Frequency, Urgency, and Urge Urinary Incontinence” (1). The registry filed them under other conditions only, most often Urinary Incontinence, Urge (6) and Lower Urinary Tract Symptoms (4).
- −58Match it another way52 name it in the title, 3 in a keyword, and 3 by a synonym or other text the search reads.
- 858The count on this page56 of them list Urinary Bladder, Overactive in their own words; the registry filed them under no condition.
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Who runs them
Astellas Pharma Inc (42) · Pfizer (35) · Allergan (24) · National Taiwan University Hospital (13) · Pamukkale University (12) · Bayer (11) · Astellas Pharma Europe B.V. (9) · Far Eastern Memorial Hospital (9)
What is being tested here
Drugs under test in Urinary Bladder, Overactive studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Mirabegron | 6 | 17 | 56 |
| Solifenacin | 5 | 17 | 54 |
| Botulinum toxin type A | 3 | 18 | 43 |
| Tolterodine | 2 | 4 | 28 |
| Onabotulinum toxin A | 2 | 5 | 10 |
| Nitrofurantoin | 2 | 0 | 2 |
| Oxybutynin | 1 | 4 | 10 |
| Lidocaine | 1 | 1 | 7 |
| Tadalafil | 1 | 0 | 4 |
| Nitrous Oxide | 1 | 0 | 2 |
Drug classes tested here Antimuscarinics 6 open · Beta-3 agonists 6 open · Estrogens 2 open · PDE5 inhibitors 1 open · NK1 receptor antagonists 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Oct 2027Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry) · Phase 3 · University of Aarhus
- Nov 2026APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women · Medstar Health Research Institute
- Nov 2026A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections · TriHealth Inc.
- Nov 2026Aquarius Pilot Study to Evaluate the New Axonics Trial System · Axonics, Inc.
- Nov 2026SGLT-2 Inhibitors and Lower Urinary Tract Symptoms · Marmara University
- Nov 2026Real-world Experiences and Voices Exploring the Actual Lived Burden of OAB: A Mixed-methods Multi-country PROMs Study on OAB Patients' Quality of Life · European Association of Urology Research Foundation
- Nov 2026The Efficacy of Transcutaneous Tibial Nerve Stimulation in Women With Idiopathic Overactive Bladder · Inonu University
- Nov 2026Effect of Neuromodulation and Therapeutic Exercise in Urinary Incontinence · Fundación Universidad Católica de Valencia San Vicente Mártir
- Nov 2026Efficacy and Safety of 7 Millimeters Vaginal Radiofrequency in Overactive Bladder · IRCCS San Raffaele
- Nov 2026Impact of TTNS on Bladder Symptoms Among People With MS, A RCT · Hawra Al-Dandan
Who these studies take
Of the 74 Urinary Bladder, Overactive studies recruiting now, 45 (61%) set no upper age limit and 15 (20%) stop at 75 or younger. 6 (8%) take children under 18. 39 (53%) are for women only and 1 (1%) for men only; 8 (11%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (8%) | 6 (8%) |
| 18 | 47 (64%) | 27 (36%) |
| 30 | 62 (84%) | 30 (41%) |
| 40 | 64 (86%) | 30 (41%) |
| 50 | 66 (89%) | 30 (41%) |
| 65 | 66 (89%) | 30 (41%) |
| 75 | 61 (82%) | 26 (35%) |
| 85 | 54 (73%) | 25 (34%) |
Across all 858 studies, recruiting or not: 20% stop at 75 or younger and 14% at 65; 10% take children; 41% are for women only and 6% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Urinary Bladder, Overactive studies take
Of 54 phase 4 interventional studies under Urinary Bladder, Overactive, half reached primary completion within 23 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 9 mo4–22 · 30 studies | 6 mo4–11 · 20 studies | — |
| Phase 2 | 17 mo11–22 · 22 studies | — | — |
| Phase 3 | 18 mo11–34 · 33 studies | 16 mo11–24 · 26 studies | — |
| Phase 4 | 23 mo15–48 · 54 studies | — | 29 mo18–51 · 42 studies |
| Interventional, no phase | 19 mo10–40 · 174 studies | 13 mo8–25 · 41 studies | 22 mo11–40 · 133 studies |
| Observational | 32 mo17–45 · 59 studies | — | 35 mo17–50 · 46 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
Newly registered1
- Parasacral TENS ProjectOct 23, 2026NCT07892417
Studies
Recruiting first, then most recently updated. Showing 50 of 858. Browse all 858 → or search them.
- Predictive Value of Inflammatory Biomarkers for Mirabegron Response in Women With Overactive BladderRecruitingNCT077735321 country
- Ambulatory Long Length URodynamics EvaluationRecruitingNCT07425015Not applicable1 country
- Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson DiseaseNot yet recruitingNCT07187466Phase 41 country
- Transcranial Direct Current Stimulation for Neurogenic Overactive Bladder Symptoms Among People With StrokeNot yet recruitingNCT07768137Not applicable1 country
- Tensi+ European Post-Market Clinical Follow-UpRecruitingNCT072054453 countries
- Parasacral TENS ProjectNot yet recruitingNCT07892417Not applicable
- A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)RecruitingNCT05685433Not applicable1 country
- Migraine Medication Effects on Urinary SymptomsEnrolling by invitationNCT062126611 country
- RELIEVE Study: NT 201 Intravesical Administration Using Vibe System (ViXe Combination Product) for the Treatment of Idiopathic Overactive BladderRecruitingNCT07553065Phase 21 country
- Pelvic Health Electrically Evoked Recording (PEER) 2 StudyRecruitingNCT05200923Not applicable1 country
- PMCF Study of the Axonics SNM System Model 5101 (R20) for the Indication of OABRecruitingNCT06789406Not applicable2 countries
- Sacral Neuromodulation for Male Overactive Bladder (MOAB)RecruitingNCT06511141Not applicable1 country
- Aquarius Pilot Study to Evaluate the New Axonics Trial SystemRecruitingNCT07335484Not applicable2 countries
- Long-Term Effectiveness and Safety of Sacral Neuromodulation With InterStim for Lower Urinary Tract DysfunctionNot yet recruitingNCT078562381 country
- Antibiotic Prophylaxis for Bladder BotoxRecruitingNCT04444440Phase 41 country
- Effectiveness of Ambulatory Transcutaneous Tibial Nerve Stimulation for Overactive BladderRecruitingNCT07540273Not applicable1 country
- Tensi+ for Treating Overactive BladderRecruitingNCT07300904Not applicable2 countries
- Efficacy and Safety of Peroneal Electric Transcutaneous Neuromodulation in the Real-world Clinical PracticeNot yet recruitingNCT077969581 country
- Flyte Device for Improving Urinary Incontinence Among Endometrial and Cervical Cancer Survivors Who Have Undergone Radiation TherapyRecruitingNCT07662824Not applicable1 country
- Cefar URO - Symptomatic Treatment of Overactive BladderRecruitingNCT06659536Not applicable1 country
- Peroneal Neuromodulation vs Pelvic Floor Exercises in OABNot yet recruitingNCT07788560Not applicable1 country
- Impact of Transcutaneous Electrical Nerve Stimulation on the Autonomic Nervous System in the Treatment of Overactive BladderNot yet recruitingNCT07781033Not applicable
- Non-invasive Saphenous Nerve Stimulation Therapy for Overactive BladderNot yet recruitingNCT07780786Phase 32 countries
- Methenamine Hippurate Following Intradetrusor OnabotulinumtoxinA InjectionRecruitingNCT06953271Phase 41 country
- Does Use of a Pre-Procedure Educational Video for Urodynamic Testing Reduces Anxiety?RecruitingNCT07740629Not applicable1 country
- Treatment Efficacy for Overactive Bladder: Comparing Education, Biofeedback, and Nerve StimulationNot yet recruitingNCT07744620Not applicable1 country
- Self-Start Triage Model for Post-Botox® Lower Urinary Tract SymptomsRecruitingNCT07648290Early Phase 11 country
- Efficacy of Transcutaneous Electrical Stimulation Therapy in the Treatment of Overactive Bladder Developing After StrokeNot yet recruitingNCT07740668Not applicable1 country
- Low-Intensity Shock Wave Therapy for Refractory Overactive Bladder in WomenNot yet recruitingNCT07739550Not applicable1 country
- Comparison of the Efficacy of Perineal and Intravaginal Electrical Stimulation in Women With Idiopathic Overactive BladderRecruitingNCT07366918Not applicable1 country
- Burden and Efficacy of Anticholinergic vs Mirabegron in Overactive Bladder - A Randomized Controlled StudyNot yet recruitingNCT07711808Phase 4
- Pretibial TENS for Pain and Anxiety During Intravesical OnabotulinumtoxinA InjectionNot yet recruitingNCT07707791Not applicable
- Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)RecruitingNCT07195656Not applicable1 country
- BTL Emsella Chair Versus Sham for the Treatment of Overactive BladderRecruitingNCT04873037Not applicable1 country
- Zinc Supplementation With Botulinum Toxin for Overactive BladderRecruitingNCT07405554Phase 21 country
- Defining the Safety and Efficacy of POSterIor Tibial NeRve StimulatiON in ChildrenNot yet recruitingNCT06769854Phase 4
- Efficacy of Probiotics for OAB Patients With AnxietyNot yet recruitingNCT07635212Not applicable1 country
- A Novel Wearable Transcutaneous Tibial Nerve Stimulation (TTNS) Device in the Treatment of Patients With Overactive Bladder (OAB) and NocturiaNot yet recruitingNCT07635251Not applicable1 country
- Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)RecruitingNCT06551246Phase 31 country
- Pilot Deprescribing of Antimuscarinic Overactive Bladder Medications in Parkinson DiseaseNot yet recruitingNCT07627529Phase 41 country
- INOPASE - Performance and Safety Study of a Personalised SNM SystemRecruitingNCT07193407Not applicable1 country
- Impact of TTNS on Bladder Symptoms Among People With MS, A RCTRecruitingNCT06341673Not applicable1 country
- The Effectiveness of Transcutaneous Sacral Neuromodulation Techniques-Magnetic Stimulation and Electrical Stimulation-on Detrusor Overactivity in Patients With Spinal Cord InjuryRecruitingNCT07578532Not applicable1 country
- Add-On ZIDA Sock Therapy for Overactive BladderRecruitingNCT07432659Not applicable1 country
- Evaluation of Autonomic Nervous System Changes in Response to Stimulation by Sacral NeuromodulationRecruitingNCT06434831Not applicable1 country
- Real-world Experiences and Voices Exploring the Actual Lived Burden of OAB: A Mixed-methods Multi-country PROMs Study on OAB Patients' Quality of LifeNot yet recruitingNCT07545148
- Low-Energy Shock Wave Therapy for Overactive Bladder in Women With Metabolic SyndromeRecruitingNCT07563764Not applicable1 country
- Vitamin D Treat-to-Target Strategy for Children With Overactive Bladder-WetRecruitingNCT06201013Not applicable1 country
- Does Position Influence the Diagnosis of Detrusor Overactivity in a Neurological PopulationRecruitingNCT05949567Not applicable1 country
- The Role of Urinary RhoA, NGF, and BDNF Levels in Overactive Bladder and Vitamin D DeficiencyNot yet recruitingNCT07513363Not applicable1 country