Spondylosis clinical trials
The registry lists 142 studies for Spondylosis across more than 10 countries. 42 are recruiting or about to start. 66 of them are mainly about Spondylosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04. Counting its narrower condition Spondylolisthesis too: 345 studies, 81 open.
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Who runs them
Riphah International University (7) · University of Medicine and Pharmacy at Ho Chi Minh City (5) · SeaSpine, Inc. (4) · Duke University (3) · Cairo University (3) · Shanghai University of Traditional Chinese Medicine (3) · Peking University Third Hospital (3) · Lahey Clinic (3)
What is being tested here
Drugs under test in Spondylosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| EC5026 | 1 | 0 | 1 |
| Ropivacaine | 0 | 0 | 1 |
| Ketorolac | 0 | 0 | 1 |
| Acetaminophen | 0 | 0 | 1 |
| Teriparatide | 0 | 0 | 1 |
| Propofol | 0 | 0 | 1 |
| Pregabalin | 0 | 0 | 1 |
| Platelet rich plasma | 0 | 0 | 1 |
| Ibuprofen | 0 | 0 | 1 |
| Dexmedetomidine | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026The NOTICE Study: Neurosurgery and OrThopedIcs Communication Evaluation Study Following Lumbar Fusions · Duke University
- Dec 2026Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials · Jiangxi University of Traditional Chinese Medicine
- Dec 2026Transcutaneous Auricular Vagus Nerve Stimulation Combined With Cervical Epidural Injection for Cervical Radiculopathy · Second Affiliated Hospital, School of Medicine, Zhejiang University
- Jan 2027Particulate vs. Non-Particulate Steroid for Sacroiliac Joint Injection · University of New Mexico
- Jan 2027Recording of Intraoperative Spinal Cord Stimulation and Monitoring · University of California, Los Angeles
- Feb 2027Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery · John O'Toole
- Mar 2027Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain · R3 Stem Cell
- Apr 2027Validity of the Turkish Translation of the Modified JOA · Izmir Democracy University
- Jul 2027RFA Using Multi-Tined Electrodes vs.Traditional Electrodes for Lumbar Spondylosis · University of Arkansas
- Aug 2027CEM-Plate and CEM-Cage First-In-Human Use Efficacy Study · ReVivo Medical, Corp.
Who these studies take
Of the 28 Spondylosis studies recruiting now, 12 (43%) set no upper age limit and 11 (39%) stop at 75 or younger. 1 (4%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (4%) | 1 (4%) |
| 18 | 20 (71%) | 20 (71%) |
| 30 | 24 (86%) | 24 (86%) |
| 40 | 27 (96%) | 27 (96%) |
| 50 | 27 (96%) | 27 (96%) |
| 65 | 23 (82%) | 23 (82%) |
| 75 | 18 (64%) | 18 (64%) |
| 85 | 13 (46%) | 13 (46%) |
Across all 142 studies, recruiting or not: 43% stop at 75 or younger and 23% at 65; 6% take children; 0% are for women only and 0% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Spondylosis studies take
Of 58 interventional studies with no phase under Spondylosis, half reached primary completion within 27 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 27 mo6–47 · 58 studies | — | 14 mo6–42 · 53 studies |
| Observational | 41 mo28–74 · 18 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 142. Browse all 142 → or search them.
- The NOTICE Study: Neurosurgery and OrThopedIcs Communication Evaluation Study Following Lumbar FusionsRecruitingNCT04140344Not applicable1 country
- Comparative Effectiveness of Two Different Approaches to Radiofrequency Ablation of Lumbar Medial Branch NervesNot yet recruitingNCT06283628Not applicable1 country
- Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture TrialsNot yet recruitingNCT07868224Not applicable1 country
- To Brace or Not to Brace for Single Level Lumbar Fusion PilotRecruitingNCT03439228Not applicable1 country
- Hard Cervical Collar Use Following Posterior Cervical FusionRecruitingNCT07789288Not applicable1 country
- Effectiveness of Pressure Biofeedback-Assisted Deep Cervical Flexor Training With and Without Scapular Stabilization Exercises on Pain, Range of Motion and Neck Disability in Cervical SpondylosisRecruitingNCT07814833Not applicable1 country
- RFA Using Multi-Tined Electrodes vs.Traditional Electrodes for Lumbar SpondylosisRecruitingNCT06477094Not applicable1 country
- Comparison of Radiographic Fusion Rate and Clinical Outcome of ALIF and XLIF Performed With Either Recombinant Human Bone Morphogenetic Protein-2 or ViviGen®RecruitingNCT05238740Not applicable1 country
- Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic PainRecruitingNCT076390601 country
- Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set RecoverNot yet recruitingNCT07766824Early Phase 11 country
- High-Frequency Electroacupuncture at Cervical Huatuo Jiaji Points Combined With Electromagnetic Field Therapy for Cervical Spondylotic RadiculopathyRecruitingNCT07712354Not applicable1 country
- Efficacy of Three-Needle Dazhui and Electroacupuncture for Cervical Spondylosis With Wind-Cold SyndromeRecruitingNCT07640126Not applicable1 country
- Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord InjuryRecruitingNCT06438471Phase 11 country
- Effects of Clinical Based Versus Synchronized Telerehabilitation on Pain, Exercise Adherence, and Functional Disability Among Patients With Grade-II Cervical Spondylosis.Not yet recruitingNCT07679373Not applicable1 country
- Catgut Embedding for Lumbar Spondylosis With Blood Stasis SyndromeRecruitingNCT07590050Not applicable1 country
- Validity of the Turkish Translation of the Modified JOARecruitingNCT074488831 country
- Transcutaneous Auricular Vagus Nerve Stimulation Combined With Cervical Epidural Injection for Cervical RadiculopathyNot yet recruitingNCT07557823Not applicable1 country
- Effect of Vestibular Rehabilitation on Evoked Myogenic Potentials in Patients With Cervical SpondylosisNot yet recruitingNCT07502625Not applicable
- PRP Injection Into the Sacroiliac Joint After Ipsilateral THA: Effects on Early Recovery and Function (SIJ-THA Randomized Trial)Not yet recruitingNCT07498660Not applicable1 country
- Regional Anesthesia in Minimally Invasive Lumbar Spine SurgeryRecruitingNCT05029726Phase 41 country
- Comparison of Artificial Disc Implants in Cervical Disc ArthroplastyRecruitingNCT057010591 country
- Dose Responsiveness as a Measure of Clinical Effectiveness During Neuromonitored Spine SurgeryEnrolling by invitationNCT051108331 country
- NuVasive® ACP System StudyEnrolling by invitationNCT050667111 country
- Particulate vs. Non-Particulate Steroid for Sacroiliac Joint InjectionRecruitingNCT06268704Phase 41 country
- Efficacy of Acupuncture at Lieque (LU7) for Neck Pain in Cervical SpondylosisNot yet recruitingNCT07151404Not applicable1 country
- Salt Water Gargling on Swallowing Following ACDFEnrolling by invitationNCT06475365Not applicable1 country
- Cupping Therapy for Neck Pain in Cervical SpondylosisNot yet recruitingNCT06893185Not applicable
- CEM-Plate and CEM-Cage First-In-Human Use Efficacy StudyRecruitingNCT04883411Not applicable1 country
- Predictors of Axial Pain Improvement After Anterior Cervical Discectomy and FusionRecruitingNCT066016341 country
- Recording of Intraoperative Spinal Cord Stimulation and MonitoringRecruitingNCT05356286Not applicable1 country
- Correlation Between Radiculopathy And Quality Of Life In Patients With Chronic Lumbar SpondylosisNot yet recruitingNCT06720103
- Radiofrequency Plus Superficial Cervical Plexus Block in Treatment of Cervical Spondylosis PainRecruitingNCT06480175Not applicable1 country
- Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar PainRecruitingNCT06361485Phase 11 country
- Enhancing Recovery in Non-Traumatic Spinal Cord InjuryRecruitingNCT03320759Not applicable1 country
- Establishing the Validity and Reliability of a Dexterity Assessment ToolRecruitingNCT059105931 country
- Effect of Cupping Therapy on Nitric Oxide Level in Patients With Cervical SpondylosisNot yet recruitingNCT06271525Not applicable
- Cervical Arthroplasty Cost Effectiveness Study (CACES)RecruitingNCT04623593Not applicable1 country
- Effects of Different Health Qigong Routines on CS Among Chinese College StudentsRecruitingNCT06130982Not applicable1 country
- Impact of Lateral Bone Grafting With Intraoperative Fusion in ACDF on Clinical OutcomesRecruitingNCT060278271 country
- OSTEOAMP Lumbar Fusion Intra-Patient Controlled StudyRecruitingNCT05405374Not applicable1 country
- Upper Trapezius Stretching in Patients With Cervical SpondylosisRecruitingNCT05920564Not applicable1 country
- Mulligan Mobilizations and McKenzie Exercises Along With Neural Mobilizations in Cervical SpondylosisRecruitingNCT05768438Not applicable1 country
- Efficacy of Electroacupuncture Combined With Auricular Acupressure for Chronic Low Back Pain.CompletedNCT07530042Not applicable1 country
- Battlefield Acupuncture as an Adjunct to Electroacupuncture for Chronic Low Back Pain Due to Lumbar Spine OsteoarthritisCompletedNCT06874959Not applicable1 country
- Patient Reported Recovery of Muscle Strength After Surgery for Cervical Radiculopathy, Impact of Duration and Severity on Recovery.CompletedNCT078255451 country
- Comparative Effects of Gong's Mobilization and Maitland Mobilization in Patients With Cervical SpondylosisCompletedNCT07808372Not applicable1 country
- PREventing Pain After SurgeryCompletedNCT05306665Not applicable1 country
- Perioperative ACT for Preventing CPSPCompletedNCT06750874Not applicable1 country
- Study on the Treatment of C/S of Qi Stagnation and Blood-stasis Type by Moving Cupping With BloodlettingCompletedNCT06093997Not applicable1 country
- Proprio Spine Measurement ToolWithdrawnNCT07023393Not applicable1 country