An observational study in Myelopathy Cervical, Cervical Spondylosis and Spinal Cord Compression, sponsored by Western University, Canada. Recruiting at 1 site in Canada. Open to participants aged 18 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-03-28.
Sponsored by Western University, Canada · Observational
Every year, thousands of Canadians are diagnosed with degenerative cervical myelopathy (DCM), a form of non-traumatic injury caused by spinal cord compression in the neck. While DCM causes a range of symptoms, one of the most disabling is loss of hand dexterity. Surgical decompression is standard treatment for DCM, but reduced dexterity often remains.
The investigators have developed a portable, easy-to-use dexterity assessment tool for measuring hand dexterity. Hand function is often assessed using tools incapable of measuring subtle changes in function, limiting a clinician's ability to monitor progression of or recovery from a disease over time. The hope is that if subtle changes in function are identified early, leading to an early DCM diagnosis and treatment, this may prevent patients from experiencing a greater loss of hand function.
The goals of this study are to determine the relationship between dexterity and myelopathy severity, as well as to establish the validity and reliability of the dexterity tool. This will be done by assessing dexterity using the dexterity tool in DCM patients (to determine the relationship between disease severity and dexterity, and measure validity) and healthy participants (to establish reliability).
142 studies on the registry are indexed under Spondylosis; 42 are open to participants now.
This study's planned enrollment of 102 is close to the median of 100 across 36 observational studies indexed under Spondylosis.
Browse Spondylosis studies →Western University, Canada is the lead sponsor of 224 studies on the registry; 56 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Cervical myelopathy patients will be recruited from a neurosurgery clinic.
Healthy participants will be recruited from individuals who accompany patients to the neurosurgery clinic, in an effort to recruit participants of a similar age to the patient participants.
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Exclusion criteria for all participants:
Patients diagnosed with degenerative cervical myelopathy; will have dexterity measured once with dexterity tool being tested.
Diagnostic Test: Dexterity Assessment Tool
Healthy volunteers will have their dexterity measured at two time points to perform reliability analysis.
Diagnostic Test: Dexterity Assessment Tool
Measures finger dexterity using pressure sensor pads.
Dexterity measurements using the Dexterity Assessment Tool in patients with cervical myelopathy
It is anticipated that disease severity will be defined based on the dexterity assessment tool
Time frame: Dexterity will be assessed at one time point, when the participant is recruited
Correlation between the Dexterity Assessment Tool and the GRASSP-M tool (Graded Redefined Assessment of Strength, Sensation and Prehension-Myelopathy)
Concurrent validity will be measured by correlating the Dexterity Assessment Tool with another validated tool, the GRASSP-M
Time frame: Dexterity will be assessed with both tools at one time point, when the participant is recruited
Correlation of dexterity measurements in healthy participants using the Dexterity Assessment Tool to measure inter-rater reliability
Inter-rater reliability will be assessed by measuring dexterity in healthy participants with two testers administering the tool one hour apart, and correlating the values from the two testers.
Time frame: Dexterity will be assessed in healthy participants at one time point, when the participant is recruited.
Correlation of dexterity measurements in healthy participants using the Dexterity Assessment Tool to measure test-retest reliability
Test-retest reliability will be assessed by measuring dexterity in healthy participants at two time points, one week apart. The data from the two time points will be correlated to determine reliability.
Time frame: Dexterity well be assessed in healthy participants at two time points, once when the participant is recruited, and once one week later.
Plan to share: No
No publications or documents are linked to this record.
Started Jun 2023 (actual). Primary completion is estimated for Jun 2024, 12 months after the start.
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