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Active, not recruitingNCT06360536OVERCOME-ITUpdated May 22, 2026

Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women

An interventional study of Resistance Training in Overweight or Obesity, Prediabetes or Diabetes and Prehypertension (Elevated Blood Pressure) or Hypertension, sponsored by University of Alabama at Birmingham. Active, not recruiting at 1 site in United States. Open to female participants aged 30 Years to 64 Years. Per ClinicalTrials.gov, last updated 2026-05-22.

Sponsored by University of Alabama at Birmingham · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
37
Allocation
Not applicable
Ages
30 Years to 64 Years
Sex
Female
01

Study summary

The purpose of this study is to collect preliminary data on the feasibility, acceptability, and potential effects of a novel, remotely delivered resistance training program.

Read the detailed description

This trial will enroll Black women with elevated cardiometabolic risk (e.g., overweight or obesity, pre- or established diabetes, and elevated or high blood pressure) in early-to-middle adulthood (n=36; age=30-64 years) with insufficient resistance training (RT) participation. This 4-month single group pilot trial evaluates the feasibility, acceptability, and potential effects of a novel, remotely-delivered resistance training (RT) intervention. All participants will engage in RT during this trial and the web-based platform is the primary modality through which the remote RT intervention is delivered. Assessments are conducted at baseline and follow-up (month 4). Aim 1 will examine the feasibility and acceptability of the remotely delivered RT program. Aim 2 will examine the potential effects on RT behaviors. Aim 3 will examine the potential effects on clinical and patient-reported outcomes.

02

Conditions studied

  • Overweight or Obesity
  • Prediabetes or Diabetes
  • Prehypertension (Elevated Blood Pressure) or Hypertension
  • Resistance Training
03

Who can participate

Ages eligible
30 Years to 64 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • Self-identifies as Black or African American
  • Female
  • Age 30-64 years
  • Insufficient resistance training engagement (\<2 sessions/week in the past 6 months)

AND

  • Self-reported or documented diagnosis of at least one of the following conditions: Overweight, obesity, prediabetes, type 2 diabetes, elevated blood pressure, hypertension, or taking medications for any of these conditions
  • Has an internet- connected device (i.e., computer, smartphone) and is willing to use it for intervention delivery
  • If indicated during screening, willing to obtain medical clearance for exercise from their healthcare provider prior to enrollment
  • Residing within a 50-mile radius of the University

Exclusion criteria

Exclusion Criteria:

  • Uncontrolled hypertension (blood pressure >160/100 mm Hg)
  • Weighing ≥ 450 lbs (upper limit for body composition assessment)
  • Conditions or limitations that affect physical activity participation and/or the ability to --perform assessments
  • Has a medical or physical condition that make moderate intensity physical activity (like a brisk walk) difficult or unsafe
  • Unwilling to obtain medical clearance (if indicated by prescreening)
  • Women who are pregnant or trying to become pregnant in the next 6 months
  • Planning to relocate out of the area in the next 6 months
  • Participating in another exercise and/or randomized research project
  • Unwilling or unable to do any of the following: give informed consent; read/understand English; perform resistance training in their home, record and upload virtual exercise assessment sessions, and other protocol specific requirements
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
37 participants (actual)

Study arms

  • Experimental
    Intervention/Treatment

    A home-based resistance training condition that is delivered through a web-based platform.

    Behavioral: Resistance Training

Interventions

  • BehavioralResistance Training

    A home-based resistance training condition that is delivered through a web-based platform.

    Also known as: RT

05

What researchers measure

Primary outcomes

  1. Feasibility of recruitment

    The number of participants enrolled in the trial

    Time frame: Baseline

  2. Feasibility of retention

    The proportion of participants who complete the study out of those who enrolled in the study

    Time frame: Month 4

  3. Intervention adherence

    The number of participants adhering to the intervention

    Time frame: Month 4

Secondary outcomes

  1. Change in resistance training behaviors

    The number of days of resistance training completed

    Time frame: Baseline and Month 4

  2. Change in blood pressure

    Systolic and diastolic blood pressure measured by an automated device

    Time frame: Baseline, Month 4

  3. Change in HbA1C

    HbA1C measured by a point-of-care device

    Time frame: Baseline, Month 4

  4. Change in body composition

    Percent body fat measured by dual-energy x-ray absorptiometry

    Time frame: Baseline, Month 4

  5. Change in handgrip strength

    The highest value of 3 maximal attempts on each hand

    Time frame: Baseline, Month 4

  6. Change in the number of chair stands

    The number of chair stands completed in 30 seconds

    Time frame: Baseline, Month 4

06

Study locations

1 site
  • University of Alabama at Birmingham
    Birmingham, Alabama 35294, United States
07

Registry details

Key details

Study ID
NCT06360536
Lead sponsor
University of Alabama at Birmingham
Collaborators
National Institute on Minority Health and Health Disparities (NIMHD)
Responsible party
Amber W. Kinsey, PhD (Assistant Professor, University of Alabama at Birmingham) — Principal investigator
First posted
Apr 11, 2024
Start date
Mar 19, 2026
Primary completion
Oct 1, 2026 (estimated)
Completion
Jun 30, 2027 (estimated)
Last update
May 22, 2026

Study contacts

Amber W Kinsey, PhD
principal investigator · University of Alabama at Birmingham

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.

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