Johnson & Johnson: Osteoarthritis trials

The registry lists 81 Osteoarthritis studies with Johnson & Johnson as lead sponsor. 1 are open to participants now and 28 have results posted.

Phase 1 2Phase 2 5Phase 3 19Phase 4 22No phase 33(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))RecruitingNCT06631638Not applicable
• PINNACLE® DM RSA StudyTerminatedNCT05357664Not applicableResults posted
• Comparison of Alignment Achieved Using the VELYS Robotic-Assisted Solution Versus Manual Instrumentation in Total Knee ArthroplastyCompletedNCT04730271Not applicableResults posted
• ATTUNE Cementless FB Tibial Base Clinical StudyTerminatedNCT04630262Not applicableResults posted
• Pinnacle RSA StudyTerminatedNCT04070989Not applicableResults posted
• GLOBAL ICON Stemless Shoulder System Post Market Clinical Follow Up StudyTerminatedNCT03168672Not applicableResults posted
• Actis Total Hip System 2 Year Follow-upCompletedNCT02783274Not applicableResults posted
• The MONOVISC Hip Osteoarthritis StudyTerminatedNCT02698865Phase 3Results posted
• ATTUNE Single-Use Instrumentation vs. ATTUNE Reusable Instrumentation in Primary Total Knee ArthroplastyCompletedNCT02574312Not applicableResults posted
• Ceramic-on-Ceramic (COC) 36mm Acetabular Bearing Insert Post Approval Study-New Subjects (COC36mmPAS)CompletedNCT02096211Not applicableResults posted
• An Efficacy and Safety Study of Fentanyl Transdermal Patch in Filipino Participants With Osteoarthritis and Chronic Low Back PainCompletedNCT01795898Phase 4Results posted
• An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Participants With OsteoarthritisCompletedNCT01774929Phase 4Results posted
• Efficacy and Safety Study of Transdermal Therapeutic System (TTS) Fentanyl in Participants With Osteoarthritis Knee PainCompletedNCT01742897Phase 4Results posted
• An Efficacy, Safety and Effects on Quality of Life of Tramadol/Paracetamol as Add-on Therapy in Chronic OsteoarthritisCompletedNCT01728246Phase 4Results posted
• Sigma CR150 Versus Sigma CR Knee RCTCompletedNCT01418378Phase 4Results posted
• An Efficacy and Safety Study for Tapentadol Extended Release (JNS024ER) in Chronic Pain ParticipantsCompletedNCT01124604Phase 2Results posted
• Switching Drug Therapy for the Prevention of Blood Clot Formation From Enoxaparin to Rivaroxaban After Orthopedic Surgery for Either Total Hip or Total Knee ReplacementCompletedNCT01094886Phase 3Results posted
• A Confirmatory Study of Fentanyl in Participants With Osteoarthritis or Low Back PainCompletedNCT01008618Phase 3Results posted
• Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the KneeCompletedNCT00980798Phase 3Results posted
• 36 mm Ceramic-on-Ceramic Acetabular Cup Total Hip ReplacementCompletedNCT00953719Not applicableResults posted
• A Study to Determine the Difference in Low Contact Stress (LCS) Duofix Versus Low LCS Porocoat Knee SystemsCompletedNCT00733499Not applicableResults posted
• A Study to Compare the Press Fit Condylar (P.F.C.) Sigma Rotating-platform High-flexion (RP-F) Versus the Press Fit Condylar (P.F.C.) Sigma Rotating-platform (RP) Knee ImplantsTerminatedNCT00733369Phase 4Results posted
• Minimally Invasive Total Knee Replacement - Navigated Versus Non-navigated StudyTerminatedNCT00733330Phase 4Results posted
• A Comparative Study of Tramadol Hydrochloride Plus Acetaminophen Tablets Maintenance Versus Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Maintenance in Participants With Knee OsteoarthritisCompletedNCT00635349Phase 4Results posted
• Multi-Center Comparative Trial of the ASR™-XL Acetabular Cup System vs. the Pinnacle™ Metal- on- Metal Total Hip SystemCompletedNCT00561600Not applicableResults posted
• Clinical Investigation of the LCS® Complete Posterior Stabilized Mobile-bearing Total Knee SystemCompletedNCT00487565Not applicableResults posted
• An Open-label Extension Study With Flexible Dosing of Extended-release (ER) Tapentadol (CG5503) to Treat Patients With Moderate to Severe Chronic PainCompletedNCT00487435Phase 3Results posted
• ORTHOVISC Shoulder Osteoarthritis StudyCompletedNCT00436969Phase 3Results posted
• A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol (CG5503) Prolonged-Release (PR) and Oxycodone Controlled-Release (CR) in Patients With Chronic PainCompletedNCT00361504Phase 3Results posted
• China ATTUNE® StudyCompletedNCT03542045
• DSJ-2016-07 ATTUNE® Cementless CR RP JapanCompletedNCT03193034Not applicable
• 14022 ATTUNE Cementless RP Clinical Performance EvaluationActive, not recruitingNCT02839850Not applicable
• A Clinical Trial Study of Knee System in Primary Total Knee Arthroplasty in ChinaCompletedNCT02399046Not applicable
• Evaluation of Post-Operative Recovery in ATTUNE® Total Knee ArthroplastyCompletedNCT02339610
• Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3002CompletedNCT02336698Phase 3
• Study of Efficacy, Safety of Fulranumab Adjunctive Use in OA of Hip or Knee, PAI3001CompletedNCT02336685Phase 3
• PS150 Total Knee Arthroplasty Outcomes RegistryCompletedNCT02319291
• Study of Safety, Efficacy of Fulranumab Adjunctive Use in OA of Hip or Knee, PAI3007CompletedNCT02301234Phase 3
• Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3003CompletedNCT02289716Phase 3
• Facet Wedge Post Market StudyCompletedNCT02203448
• Ceramic On Ceramic (COC) 36mm PAS IDE Rollover Subjects; Ceramic Acetabular Bearing With Ceramic Femoral Head in Total Hip ReplacementCompletedNCT02096198
• Survivorship of Attune Primary Total Knee ProsthesisActive, not recruitingNCT01754363Not applicable
• Prospective, Multiconfiguration Study to Assess Functional Performance of Primary Total Knee Arthroplasty SystemCompletedNCT01746524
• 28mm Ceramic-on-Ceramic Total Hip Replacement StudyTerminatedNCT01657435
• An Open-label Evaluation of Tapentadol Extended Release (ER) in Participants With Moderate to Severe Chronic Pain After Conversion From Hydrocodone, Oxycodone Controlled Release (CR), and/or Morphine Sustained Release (SR)WithdrawnNCT01631513Phase 4
• CoMplete™ Acetabular Hip SystemTerminatedNCT01543230Not applicable
• Postmarketing Study to Determine Performance of the SIGMA HP® PARTIAL KNEE SYSTEMCompletedNCT01529099Phase 4
• 10003 PRO Current ProductsCompletedNCT01497730
• A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-39439335 in Patients With OsteoarthritisCompletedNCT01343303Phase 1
• A Controlled Study of an Herbal Topical Patch in Treating Osteoarthritis (OA) of the KneeCompletedNCT01183624Phase 4
• Observational Study Investigating the Effectiveness of Fentanyl Matrix in Relieving Pain and Improving Function in Patients With Osteoarthritis of the Knee or HipCompletedNCT01119885
• A Safety and Tolerability Study of JNJ-42160443 in Patients With Moderate to Severe, Chronic Knee Pain From OsteoarthritisTerminatedNCT01094262Phase 2
• A Study of the Tolerability of Titrated Dose Tramadol/Acetaminophen Combination Tablet in Korean Patients With OsteoarthritisCompletedNCT01063842Phase 4
• Treatment of Medial Compartmental Osteoarthritis Grade 1-4 With TomoFix™ Small or ConservativelyCompletedNCT01048710
• A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Osteoarthritis-related PainTerminatedNCT00973141Phase 2
• A Clinical Study to Investigate the Effect on Pain Relief of a Single Dose of JNJ-39439335 in Patients With Chronic Osteoarthritis Pain of the KneeCompletedNCT00933582Phase 1
• Study to Assess the Stability, Efficacy and Safety of the Silent™ Hip Prosthesis in Primary Total Hip ReplacementCompletedNCT00894140Not applicable
• Multi-centre Study to Assess Long-term Safety and Efficacy of the Silent™ Hip Prosthesis in Primary THRTerminatedNCT00878046Not applicable
• Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip ReplacementTerminatedNCT00872547Phase 4
• A Study to Determine the Performance of the Press Fit Condylar (P.F.C.) Sigma RP-F Knee SystemTerminatedNCT00761410Phase 4
• An Exploratory Study of Tramadol Hydrochloride in Patients With Osteoarthritis of the Knee or Low Back PainCompletedNCT00752661Phase 2
• Efficacy and Safety of Tapentadol Extended Release Tablets in the Treatment of Moderate to Severe Pain in Subjects With Knee OsteoarthritisCompletedNCT00745069Phase 2
• Long-term Clinical Effectiveness of the Delta Xtend Reverse Total ShoulderTerminatedNCT00737087Not applicable
• A Study to Evaluate the DePuy Minimally Invasive Unicompartmental KneeTerminatedNCT00734084Phase 4
• Survivorship of the Press Fit Condylar (P.F.C.) Sigma Fixed Bearing Knee With a Cobalt Chrome Tibial TrayCompletedNCT00734019
• The Press Fit Condylar (P.F.C.) Sigma Metal-backed Versus All-polyCompletedNCT00733928Phase 4
• Outcome Study of Total Knee Arthroplasty in Asian PatientsCompletedNCT00733694Phase 4
• The Press Fit Condylar (P.F.C.) Sigma Rotating Platform (RP) TC3 Revision Knee in Revision Knee ArthroplastyTerminatedNCT00733681Phase 4
• A Study to Evaluate the Performance of the DePuy Low Contact Stress (LCS®) Complete Anterior-Posterior Glide (APG) Mobile Bearing KneeTerminatedNCT00733486Phase 4
• Global® AP™ Total Shoulder ArthroplastyCompletedNCT00719771Not applicable
• A Four-Week Study Comparing Acetaminophen Extended Release and Rofecoxib in the Treatment of Osteoarthritis of the KneeCompletedNCT00568295Phase 3
• A Study of the Effect on Pain Control of Treatment With Fentanyl, Administered Through the Skin, in Patients With Rheumatoid Arthritis or OsteoarthritisCompletedNCT00524160Phase 4
• A Study to Evaluate the Effectiveness and Safety of Slow Release Hydromorphone HCL for Treatment of Patients With OsteoarthritisCompletedNCT00411164Phase 3
• An Effectiveness, Safety and Quality of Life Measures With Hydromorphone HCL, Dilaudid CR (Controlled Release)CompletedNCT00399048Phase 3
• A Study to Evaluate 90-Day Safety of Tapentadol(CG5503) Immediate Release (IR) or Oxycodone Immediate Release in Patients With Chronic PainCompletedNCT00364546Phase 3
• A Study to Evaluate the Effectiveness and Safety of Multiple Doses of Tapentadol(CG5503) in Patients Awaiting Joint Replacement SurgeryCompletedNCT00361582Phase 3
• An Effectiveness and Safety Study of Acetaminophen Extended Release Caplets in the Treatment of Osteoarthritis of the Hip or Knee.CompletedNCT00240799Phase 3
• An Effectiveness and Safety Study of Two Doses of Acetaminophen Extended Release Caplets in the Treatment of Osteoarthritis of the Hip or KneeCompletedNCT00240786Phase 3
• A Safety and Effectiveness Study of Acetaminophen (4000 mg/Day) and Naproxen (750 mg/Day) in the Treatment of Osteoarthritis of the Hip or KneeCompletedNCT00240773Phase 3
• A Study of the Effect on Pain Control of Treatment With Fentanyl, Administered Through the Skin, Compared With Placebo in Patients With OsteoarthritisCompletedNCT00236366Phase 4
• A Randomised Multi-centre Study to Compare the Short-term Outcomes of Minimally Invasive and Conventional Surgery in Primary Total Hip ReplacementTerminatedNCT00208416Phase 4