Pfizer: Osteoarthritis trials

The registry lists 39 Osteoarthritis studies with Pfizer as lead sponsor. 2 are open to participants now and 20 have results posted.

Early Phase 1 1Phase 1 7Phase 2 9Phase 3 21Phase 4 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study to Learn About Study Medicine Called Berobenatide in Adults With Knee Pain and Overweight or Obesity (VESPER-OA 1)RecruitingNCT07919678Phase 3
• A Study to Learn About Berobenatide Given Once Weekly in Adults With Knee Osteoarthritis and Overweight or Obesity With or Without Type 2 Diabetes (VESPER-OA 2)RecruitingNCT07915609Phase 3
• Protocol to Monitor the Neurological Development of Infants With Exposure in Utero From Birth to 15 Months in Tanezumab Clinical StudiesCompletedNCT03031938Phase 3Results posted
• Study of the Analgesic Efficacy and Safety of Subcutaneous Tanezumab in Subjects With Osteoarthritis of the Hip or Knee.CompletedNCT02709486Phase 3Results posted
• Long-term Observational Study of Subjects From Tanezumab Studies Who Undergo a Total Knee, Hip or Shoulder ReplacementCompletedNCT02674386Phase 3Results posted
• A Study Of The Safety And Efficacy Of PF-04191834 In Patients With Osteoarthritis Of The KneeTerminatedNCT01147458Phase 2Results posted
• Safety Extension Study Of Tanezumab When Administered By Subcutaneous Injection To Patients With OsteoarthritisTerminatedNCT01127893Phase 3Results posted
• Efficacy And Safety Study Of Tanezumab Subcutaneous Administration In Osteoarthritis - A Subcutaneous/Intravenous Bridging StudyTerminatedNCT01089725Phase 3Results posted
• Tanezumab In Osteoarthritis Of The Hip Or KneeTerminatedNCT00985621Phase 3Results posted
• Long-Term Study Of The Safety Of Tanezumab In Arthritis PatientsTerminatedNCT00960804Phase 3Results posted
• Analgesic Efficacy And Safety of Tanezumab Added On To Diclofenac SR In Patients With Osteoarthritis Of The Knee Or HipTerminatedNCT00864097Phase 3Results posted
• Tanezumab and Nerve Function In Arthritis PatientsTerminatedNCT00863772Phase 3Results posted
• Tanezumab in Osteoarthritis of the Hip or Knee (2)CompletedNCT00863304Phase 3Results posted
• Tanezumab In Osteoarthritis Of The Knee (2)CompletedNCT00830063Phase 3Results posted
• Extension Study Of Tanezumab In OsteoarthritisTerminatedNCT00809783Phase 3Results posted
• Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or HipTerminatedNCT00809354Phase 3Results posted
• Tanezumab in Osteoarthritis Of The HipCompletedNCT00744471Phase 3Results posted
• Tanezumab in Osteoarthritis of the KneeCompletedNCT00733902Phase 3Results posted
• A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the KneeCompletedNCT00565812Phase 2Results posted
• Measuring Gait And Self-Reported Pain In Patients With Osteoarthritis Of The Knee Using Placebo/Oxycodone/Celecoxib.TerminatedNCT00484718Phase 4Results posted
• A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or KneeCompletedNCT00420992Phase 3Results posted
• Open-label Extension Study Of RN624CompletedNCT00399490Phase 2Results posted
• X-Ray Study Investigating The Safety And Efficacy Of SD-6010 In Subjects With Osteoarthritis Of The KneeWithdrawnNCT01438918Phase 3
• A Study of ARRY-371797 in Patients With Osteoarthritis of the KneeCompletedNCT01366014Phase 2
• Clinical Trial to Examine the Pain Relief of PH-797804 Alone Or With Naproxen in Subjects With Osteoarthritis of the KneeCompletedNCT01102660Phase 2
• Study To Assess Changes In The Number Of Nerves In The Skin At The Site Where Where Tanezumab Is InjectedCompletedNCT01030640Phase 1
• Brain Imaging To Examine The Effect Of Naproxen In Hand Osteoarthritis PatientsCompletedNCT00830050Early Phase 1
• A Study To Assess The Ability Of Tramadol, Naproxen And Oxycodone To Affect The Pain Thresholds Of Patients With Osteoarthritis Of The ThumbCompletedNCT00743587Phase 1
• Double-Blind, Double Dummy, Randomized Comparison Study to Evaluate the Efficacy and Safety of Valdecoxib 10 mg Once Daily and Naproxen 500 mg Twice Daily in Treating the Signs and Symptoms of Osteoarthritis of the KneeCompletedNCT00652808Phase 3
• A Double-Blind, Double Dummy, Randomized Comparison Study Of The Efficacy And Safety Of Valdecoxib 10mg Once Daily And Naproxen 500mg Twice Daily In Treating The Signs And Symptoms Of Osteoarthritis Of The Knee Or Hip In TaiwanCompletedNCT00648258Phase 3
• A 2 Week Blinded Study For Pain Due To Arthritis Of The KneeTerminatedNCT00483977Phase 2
• Study Evaluating AGG-523 in Subjects With Severe Osteoarthritis Requiring Total Knee ReplacementCompletedNCT00454298Phase 1
• Study Evaluating AGG-523 in Subjects With OsteoarthritisCompletedNCT00427687Phase 1
• A Study Of The Effect Of CE-224535 On Knee OA (Osteoarthritis) PainTerminatedNCT00418782Phase 2
• A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The KneeTerminatedNCT00396955Phase 2
• A Phase II Study Looking at Moderate to Severe Osteoarthritis Knee PainCompletedNCT00394563Phase 2
• A Study Of The Effect Of CJ-023,423 On The Incidence Of Stomach UlcersCompletedNCT00392080Phase 1
• Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in HealthyCompletedNCT00380900Phase 1
• Study Evaluating rhMBP-2/CPM in Open Wedge OsteotomiesCompletedNCT00243295Phase 1