Optic Neuritis: all 88 studies

Page 1 of 1. Open to participants first (16), then studies with results posted, then the rest; newest registration first within each.

• Early Prediction of Outcomes Following Optic Neuritis: Development and Acceptability of a Prognostic ToolNot yet recruitingNCT07704294
• Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation ResearchRecruitingNCT07623668Phase 3
• Prospective Evaluation of the 2022 Optic Neuritis Criteria When Optic Neuritis Is SuspectedRecruitingNCT07623252
• Modified Zipper Therapy for AQP4-IgG Positive Neuromyelitis Optica Spectrum DisorderRecruitingNCT07420296Phase 3
• Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)RecruitingNCT07100990Phase 3
• Evaluation of Optic Neuritis Using Synthetic Quantitative MRINot yet recruitingNCT06916182
• Efgartigimod for the Treatment of Acute Optic NeuritisRecruitingNCT06453694Phase 2
• Light Stimulation to Improve Visual Function After Optic Neuritis in Persons with Multiple SclerosisRecruitingNCT06389968Not applicable
• Acute Optic Neuritis Network: an International Study That Invesitages Subjects With a First-ever Episode of Acute Inflammation of the Optic NerveRecruitingNCT05605951
• Edaravone in the Treatment of Optic NeuritisRecruitingNCT05540262Not applicable
• VIsual Pathways Model in Neuro-inflammatory DisordersRecruitingNCT05487989
• Azathioprine in MOGADRecruitingNCT05349006Phase 3
• Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)RecruitingNCT05017142
• Retinal Neuro-vascular Coupling in Patients With Multiple SclerosisRecruitingNCT03401879Not applicable
• Optic Neuritis Differential Diagnosis StudyRecruitingNCT03370965Not applicable
• Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)RecruitingNCT02521311Phase 2
• An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSDCompletedNCT04201262Phase 3Results posted
• A Study of the Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum DisorderTerminatedNCT04155424Phase 2/3Results posted
• Effect of Phenytoin on the Ganglion Cell Layer in Patients With Optic NeuritisCompletedNCT02939937Phase 2Results posted
• Long-Term Assessment of Remyelinating TherapyCompletedNCT02657915Phase 2Results posted
• Ublituximab for Acute Neuromyelitis Optica (NMO) RelapsesCompletedNCT02276963Phase 1Results posted
• Electric Stimulation of the Eye to Improve Vision After TraumaCompletedNCT02019927Not applicableResults posted
• An Open Label Extension Trial of Eculizumab in Relapsing NMO PatientsCompletedNCT02003144Phase 3Results posted
• A Randomized Controlled Trial of Eculizumab in AQP4 Antibody-positive Participants With NMO (PREVENT Study)TerminatedNCT01892345Phase 3Results posted
• Fingolimod (FTY720) in Acute Demyelinating Optic Neuritis (ADON)TerminatedNCT01757691Phase 2Results posted
• BIIB033 In Acute Optic Neuritis (AON)CompletedNCT01721161Phase 2Results posted
• Ampyra for Optic Neuritis in Multiple SclerosisCompletedNCT01337986Phase 2/3Results posted
• A Randomized, Double-blind, Placebo-controlled, Multicenter Study of the Effects of Glatiramer Acetate (GA) on the Retinal Nerve Fiber Layer (RNFL) and Visual Function in Patients With a First Episode of Acute Optic Neuritis (AON). (Octagon)CompletedNCT00856635Phase 3Results posted
• Atacicept in Subjects With Optic NeuritisTerminatedNCT00624468Phase 2Results posted
• Long Term Study of Avonex Therapy Following a First Attack of Multiple SclerosisCompletedNCT00179478Phase 4Results posted
• Visual (Path)Ways in Multiple Sclerosis - Part IICompletedNCT06776224Not applicable
• Building Research With Artificial Intelligence in Neuro-OphthalmologyCompletedNCT06390579
• Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.TerminatedNCT05353413Not applicable
• Retrobulbar Methylprednisolone as Adjunctive Treatment in Optic Neuritis TrialStatus unknownNCT04942002Phase 2/3
• Post-COntrast 3D SE T1 Versus Coronal SE T1-WI MRI in Detecting Optic Neuritis (COCON)CompletedNCT04793087
• 3D FLAIR Versus Coronal T2-WI MRI in Detecting Optic Neuritis (FLACON)CompletedNCT04792866
• OCS-05 in Patients With Optic NeuritisCompletedNCT04762017Phase 2
• A Multi-Center, Open-Label Long-Term Extension Study of CNM-Au8 In Patients With Stable Relapsing Multiple SclerosisCompletedNCT04626921Phase 2/3
• Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics (RETIMUS)CompletedNCT04289909Not applicable
• Epidemiologic and Clinical Characteristics of Optic Neuritis in ChinaStatus unknownNCT04257734
• Fampridine-SR and Optic Neuritis RecoveryStatus unknownNCT04148781Early Phase 1
• Diagnosis of ON With or Without MS or NMOSDTerminatedNCT04131764
• Effect of Transorbital Electrical STIMulation of Optic Nerve on Remyelination After an Acute Optic NeuritisStatus unknownNCT04042363Not applicable
• Optical Coherence Tomography and Optic Neuritis Not Related to Multiple SclerosisCompletedNCT03963310
• Repetitive Transorbital Alternating Current Stimulation in Acute Autoimmune Optic NeuritisTerminatedNCT03862313Not applicable
• Ocular Manifestations in Rheumatic DiseasesCompletedNCT03753893
• Linking Optic Nerve MRI and the Retinal Axonal Loss After Optic NeuritisCompletedNCT03651362
• BN201 SAD MAD Study in Healthy SubjectsCompletedNCT03630497Phase 1
• Effectiveness of Plasma Exchange in Treating With Severe Acute AQP4-Ab Positive Optic NeuritisStatus unknownNCT03586557Not applicable
• Can Diffusion Tensor Imaging (DTI) of the Optic Ways Contributes to Predict the 6 Months Prognosis of Optic Neuritis (ON)?CompletedNCT03570385Not applicable
• The Effect of a Gluten Free Diet on the Permeability of the Blood Brain Barrier in Patients With CISCompletedNCT03451955Not applicable
• Initial Clinical Presentation of Inflammatory Optic Neuritis Associated or Not With Autoantibodies Anti-Myelin-oligodendrocyte-glycoproteinCompletedNCT03345537
• High-Dose Vitamin D Induction in Optic NeuritisTerminatedNCT03302585Phase 2
• Adjunctive Gypenosides for Acute Optic NeuritisTerminatedNCT02976766Phase 2
• Pupillometry Dynamic Measures in Patients Without Ocular or Neurological DiseaseCompletedNCT02894281
• The Correlation Between AQP-4 Ab and the Visual Function of Patients With Demyelinating ON at OnsetStatus unknownNCT02886377
• Optic Neuritis and Ganglion Cell LayerCompletedNCT02864134
• The French Cohort and Biobank of Devic's Neuromyelitis Optica and Related Neurological Disorders (NMOSD) (NOMADMUS)CompletedNCT02850705
• CHRONIC OPTIC NEUROPATHY IN MULTIPLE SCLEROSISCompletedNCT02543788Not applicable
• Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple SclerosisStatus unknownNCT02220244Phase 3
• Pilot Study of alpha1-antitrypsin to Treat Neuromyelitis Optica RelapsesWithdrawnNCT02087813Phase 1
• Interest of Dynamic Measures of the Pupil in Optic NeuritisCompletedNCT02004054
• Defining the Functional and Neuro-Protective Potential of ACTHAR in Acute Optic NeuritisCompletedNCT01987167Early Phase 1
• Treatment of Optic Neuritis With Erythropoietin: a Randomised, Double-blind, Placebo-controlled TrialCompletedNCT01962571Phase 3
• Natural History of Optic NeuritisTerminatedNCT01851434
• A Trial of Neuroprotection With ACTH in Acute Optic NeuritisTerminatedNCT01838174Phase 4
• Amiloride Clinical Trial In Optic NeuritisCompletedNCT01802489Phase 2
• Optical Coherence Tomography in Multiple Sclerosis PatientsCompletedNCT01774123
• The Longitudinal CONQUER Study of Rare Neuroimmunologic DisordersActive, not recruitingNCT01623076
• Optic Neuritis Recovery After Oral or IV CorticosteroidsCompletedNCT01524250Phase 2/3
• Effect of Vitamin D on Retinal Changes in Patient With Optic Neuritis by Optic Coherence TomographyStatus unknownNCT01465893Phase 2
• Neuroprotection With Phenytoin in Optic NeuritisCompletedNCT01451593Phase 2
• TLR-9 Antagonism in Steroid Resistant Optic NeuritisCompletedNCT01424735Not applicable
• Lipoic Acid as a Treatment for Acute Optic NeuritisCompletedNCT01294176Phase 1
• Visual Reconstitution Therapy After Optic NeuritisCompletedNCT01274702Phase 2
• AIMSPRO in the Treatment of Bladder Dysfunction in Secondary Progressive Multiple SclerosisStatus unknownNCT01228396Phase 2
• Neuroprotection and Repair in Optic NeuritisTerminatedNCT01073813Phase 2
• Safety Study of a Single IVT Injection of QPI-1007 in Chronic Optic Nerve Atrophy and Recent Onset NAION PatientsCompletedNCT01064505Phase 1
• Evaluation of Neural Loss in Multiple Sclerosis and Neuromyelitis Optica Using High Resolution OctStatus unknownNCT01024985
• Biobank For MS And Other Demyelinating DiseasesActive, not recruitingNCT00445367
• Mesenchymal Stem Cells in Multiple Sclerosis (MSCIMS)CompletedNCT00395200Phase 1/2
• Safety and Efficacy Study of Erythropoietin as add-on Therapy of Methylprednisolone to Treat Acute Optic NeuritisCompletedNCT00355095Phase 2
• Effect of High-Dose Prednisolone (Solu Dacortin®) Treatment on Choroidal and Optic Nerve Head Blood Flow in HumansCompletedNCT00312325Phase 4
• Simvastatin Treatment of Patients With Acute Optic NeuritisStatus unknownNCT00261326Phase 3
• Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event.WithdrawnNCT00037115Phase 4
• Longitudinal Optic Neuritis Study (LONS)Status unknownNCT00000147Not applicable
• Optic Neuritis Treatment Trial (ONTT)Status unknownNCT00000146Phase 3
• Intravenous Immunoglobulin Therapy in Optic NeuritisCompletedNCT00000117Phase 3

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