An observational study in Optic Neuritis and Multiple Sclerosis, sponsored by Fondation Ophtalmologique Adolphe de Rothschild. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-03-15.
Sponsored by Fondation Ophtalmologique Adolphe de Rothschild · Observational
3D FLAIR, 3D T1 FAT SAT, coronal T2 and coronal T1 dixon sequences were usually used to assess visual deficits in MRI. Optic nerve examination is preferably performed using a coronal T2 sequence in order to detect a hypersignal suggestive of inflammation whereas brain examination is preferably performed using a 3D T1 sequence to highlight signs of spatial dissemination and lesions suggestive of multiple slerosis (MS). No study has yet investigated the detection capabilities of 3D T1 for the detection of optic nerve inflammation. The objective of this retrospective study was to determine whether a single 3D T1 sequence allows simultaneous exploration of the optic nerve and the brain for the positive diagnosis of optic neuropathy and/or MS.
88 studies on the registry are indexed under Optic Neuritis; 16 are open to participants now.
This study's enrollment of 1,200 is above the median of 150 across 25 observational studies indexed under Optic Neuritis.
Browse Optic Neuritis studies →Fondation Ophtalmologique Adolphe de Rothschild is the lead sponsor of 316 studies on the registry; 78 are open to participants now.
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Patients with visual acuity loss explored by MRI between january 2018 and january 2020
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Comparing 3D T1 versus coronal T1 MRI in detecting Optic Neuritis
Detection of optic neuropathies using MRI
MRI comparison of the diagnostic performance of the 3D T1 sequence and the T1 coronal in the detection of optic neuropathies.
Time frame: 1 hour
Ran from Jan 2018 to primary completion in Jan 2018, 0 months.
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This study is completed, as verified in Mar 2021. You cannot join it, but the record below documents what was studied.
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