An observational study in Optic Neuritis, Multiple Sclerosis and Encephalopathy, sponsored by Fondation Ophtalmologique Adolphe de Rothschild. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-03-15.
Sponsored by Fondation Ophtalmologique Adolphe de Rothschild · Observational
3D FLAIR, 3D T1 FAT SAT, coronal T2 and coronal T1 dixon sequences were usually used to assess visual deficits in MRI. Optic nerve examination is preferably performed using a coronal T2 sequence in order to detect a hypersignal suggestive of inflammation whereas brain examination is preferably performed using a 3D FLAIR sequence to highlight signs of spatial dissemination and lesions suggestive of multiple slerosis (MS).
Recently, a study based on a small number of patients showed the interest of 3D FLAIR in the detection of the hypersignal of the optic nerve.The objective of this retrospective study is to determine whether a single 3D FLAIR sequence allows simultaneous exploration of the optic nerve and the brain for the positive diagnosis of optic neuropathy and/or MS.
88 studies on the registry are indexed under Optic Neuritis; 16 are open to participants now.
This study's enrollment of 1,200 is above the median of 150 across 25 observational studies indexed under Optic Neuritis.
Browse Optic Neuritis studies →Fondation Ophtalmologique Adolphe de Rothschild is the lead sponsor of 316 studies on the registry; 78 are open to participants now.
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Patients presenting with acute visual loss and explored by MRI
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Comparing 3D FLAIR versus Coronal T2-WI MRI in detecting Optic Neuritis
Detection of optic neuropathies using MRI
MRI comparison of the diagnostic performance of the 3D FLAIR sequence and the T2 coronal in the detection of optic neuropathies.
Time frame: 1 hour
Ran from Jan 2018 to primary completion in Mar 2020, 26 months.
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This study is completed, as verified in Mar 2021. You cannot join it, but the record below documents what was studied.
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