Optic Neuritis clinical trials
The registry lists 81 studies for Optic Neuritis across more than 10 countries. 16 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Completed
- 39
- Recruiting
- 14
- Status unknown
- 13
- Terminated
- 10
- Active, not recruiting
- 2
- Not yet recruiting
- 2
Phase
- Phase 2
- 22
- Phase 3
- 14
- Phase 1
- 4
- Phase 4
- 3
- Early Phase 1
- 2
Where
- United States
- 24
- France
- 22
- United Kingdom
- 10
- Germany
- 10
- Canada
- 10
- China
- 7
Who runs them
Fondation Ophtalmologique Adolphe de Rothschild (8) · Biogen (3) · University Hospital, Lille (3) · First Affiliated Hospital of Guangxi Medical University (3) · National Eye Institute (NEI) (3) · Chinese PLA General Hospital (2) · Medical University of Vienna (2) · University of Calgary (2)
Studies
Recruiting first, then most recently updated. Showing 50 of 81 — search for more.
- Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)RecruitingNCT07100990Phase 31 country
- Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation ResearchRecruitingNCT07623668Phase 31 country
- Early Prediction of Outcomes Following Optic Neuritis: Development and Acceptability of a Prognostic ToolNot yet recruitingNCT077042941 country
- Prospective Evaluation of the 2022 Optic Neuritis Criteria When Optic Neuritis Is SuspectedRecruitingNCT076232521 country
- Modified Zipper Therapy for AQP4-IgG Positive Neuromyelitis Optica Spectrum DisorderRecruitingNCT07420296Phase 31 country
- Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)RecruitingNCT02521311Phase 21 country
- Efgartigimod for the Treatment of Acute Optic NeuritisRecruitingNCT06453694Phase 21 country
- VIsual Pathways Model in Neuro-inflammatory DisordersRecruitingNCT054879891 country
- Retinal Neuro-vascular Coupling in Patients With Multiple SclerosisRecruitingNCT03401879Not applicable1 country
- Evaluation of Optic Neuritis Using Synthetic Quantitative MRINot yet recruitingNCT06916182
- Edaravone in the Treatment of Optic NeuritisRecruitingNCT05540262Not applicable1 country
- Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)RecruitingNCT050171421 country
- Light Stimulation to Improve Visual Function After Optic Neuritis in Persons with Multiple SclerosisRecruitingNCT06389968Not applicable1 country
- Comparison of Diagnostic Performances of 3D FLAIR, DIR and PSIR Sequences in Optic NeuritisRecruitingNCT064942281 country
- Acute Optic Neuritis Network: an International Study That Invesitages Subjects With a First-ever Episode of Acute Inflammation of the Optic NerveRecruitingNCT0560595117 countries
- Optic Neuritis Differential Diagnosis StudyRecruitingNCT03370965Not applicable1 country
- Adjunctive Gypenosides for Acute Optic NeuritisTerminatedNCT02976766Phase 21 country
- Visual (Path)Ways in Multiple Sclerosis - Part IICompletedNCT06776224Not applicable1 country
- Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics (RETIMUS)CompletedNCT04289909Not applicable1 country
- The Longitudinal CONQUER Study of Rare Neuroimmunologic DisordersActive, not recruitingNCT016230761 country
- Linking Optic Nerve MRI and the Retinal Axonal Loss After Optic NeuritisCompletedNCT036513621 country
- An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSDCompletedNCT04201262Phase 313 countries
- Biobank For MS And Other Demyelinating DiseasesActive, not recruitingNCT004453671 country
- OCS-05 in Patients With Optic NeuritisCompletedNCT04762017Phase 21 country
- Building Research With Artificial Intelligence in Neuro-OphthalmologyCompletedNCT063905791 country
- CHRONIC OPTIC NEUROPATHY IN MULTIPLE SCLEROSISCompletedNCT02543788Not applicable1 country
- Optical Coherence Tomography and Optic Neuritis Not Related to Multiple SclerosisCompletedNCT039633101 country
- Expression of PARP-1 in Multiple Sclerosis PatientsCompletedNCT05196425Not applicable1 country
- High-Dose Vitamin D Induction in Optic NeuritisTerminatedNCT03302585Phase 21 country
- A Trial of Neuroprotection With ACTH in Acute Optic NeuritisTerminatedNCT01838174Phase 41 country
- Nanocrystalline Gold to Treat Remyelination Failure in Chronic Optic Neuropathy In Multiple SclerosisTerminatedNCT03536559Phase 23 countries
- The Effect of a Gluten Free Diet on the Permeability of the Blood Brain Barrier in Patients With CISCompletedNCT03451955Not applicable1 country
- Can Diffusion Tensor Imaging (DTI) of the Optic Ways Contributes to Predict the 6 Months Prognosis of Optic Neuritis (ON)?CompletedNCT03570385Not applicable1 country
- Natural History of Optic NeuritisTerminatedNCT018514342 countries
- Initial Clinical Presentation of Inflammatory Optic Neuritis Associated or Not With Autoantibodies Anti-Myelin-oligodendrocyte-glycoproteinCompletedNCT033455371 country
- Fampridine-SR and Optic Neuritis RecoveryStatus unknownNCT04148781Early Phase 11 country
- Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.Status unknownNCT05353413Not applicable1 country
- Ocular Manifestations in Rheumatic DiseasesCompletedNCT03753893
- Effectiveness of Plasma Exchange in Treating With Severe Acute AQP4-Ab Positive Optic NeuritisStatus unknownNCT03586557Not applicable1 country
- MOdification of VIsual Outcomes After Optic Neuritis in CIS or MS by Gilenya (MOVING Study)TerminatedNCT01647880Phase 2/31 country
- Visual Reconstitution Therapy After Optic NeuritisCompletedNCT01274702Phase 21 country
- Retrobulbar Methylprednisolone as Adjunctive Treatment in Optic Neuritis TrialStatus unknownNCT04942002Phase 2/31 country
- Optical Coherence Tomography and Optic Neuritis (OCTON)CompletedNCT025737921 country
- Repetitive Transorbital Alternating Current Stimulation in Acute Autoimmune Optic NeuritisTerminatedNCT03862313Not applicable1 country
- Post-COntrast 3D SE T1 Versus Coronal SE T1-WI MRI in Detecting Optic Neuritis (COCON)CompletedNCT047930871 country
- 3D FLAIR Versus Coronal T2-WI MRI in Detecting Optic Neuritis (FLACON)CompletedNCT047928661 country
- Epidemiologic and Clinical Characteristics of Optic Neuritis in ChinaStatus unknownNCT042577341 country
- Ampyra for Optic Neuritis in Multiple SclerosisCompletedNCT01337986Phase 2/31 country
- Treatment of Optic Neuritis With Erythropoietin: a Randomised, Double-blind, Placebo-controlled TrialCompletedNCT01962571Phase 31 country
- Long-Term Assessment of Remyelinating TherapyCompletedNCT02657915Phase 211 countries