Drug
Edaravone clinical trials
Also written MCI-186, Radicut, MT-1186 and Radicava.
- studies test it
- 36
- open now
- 4
- in phase 3
- 6
- first study started
- 2001
Keep track of what changes. Save the Edaravone studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Combined with it in one product
Studies by the year they started
36 studies that test it; most in 2021 (6)
| Year | Studies |
|---|---|
| 2001 | 1 |
| 2004 | 2 |
| 2006 | 2 |
| 2007 | 1 |
| 2009 | 2 |
| 2011 | 1 |
| 2013 | 1 |
| 2016 | 3 |
| 2017 | 1 |
| 2018 | 4 |
| 2019 | 5 |
| 2020 | 2 |
| 2021 | 6 |
| 2022 | 2 |
| 2023 | 1 |
| 2024 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 13
- Phase 2
- 9
- Phase 3
- 6
- Phase 4
- 6
- No phase
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 20 · Other 16
Shionogi (18) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (2) · Shanghai Auzone Biological Technology Co., Ltd. (1) · Hui-Sheng Chen (1) · Nanjing Yoko Biomedical Co., Ltd. (1) · Kumamoto University (1) · Combination Therapy for Acute Ischemic Stroke Study Group (1) · Yi Yang (1)
Often tested with
Tested in the same studies.
Dexborneol (7) · Taurine (1) · Nerve Growth Factor (1) · Scopolamine (1) · Atropine (1) · Dexmedetomidine (1) · Urinastatin (1) · Tranexamic Acid (1)
Studies
Open first, then newest update. How each study uses Edaravone is read from its arms, and is right about nine times in ten.
Testing it · 36
- Edaravone and Dexborneol Sublingual Tablet for Treating Chemotherapy- Induced Cognitive Impairment StudyRecruitingPhase 4Chuansheng ZhaoNCT07454473Written as Edaravone Dexborneol
- Edaravone in the Treatment of Optic NeuritisRecruitingNot applicableFirst Affiliated Hospital of Guangxi Medical UniversityNCT05540262Written as Edaravone
- Safety and Efficacy of Edaravone Dexborneol for Acute Ischemic StrokeNot yet recruitingPhase 4Yi YangNCT06645522Written as Edaravone dexborneol
- Treatment of Acute Ischemic Stroke With Rt-PA Combined With Edaravone DexborneolRecruitingPhase 4The Second Hospital of Hebei Medical UniversityNCT06248242Written as Edaravone dexborneol
- Edaravone-Sodium Ozagrel Comparative Post-Marketing Study on Acute Ischemic StrokeCompletedPhase 4ShionogiNCT00200356Written as Edaravone
- Phase 3 Study of MCI-186 for Treatment of Amyotrophic Lateral SclerosisCompletedPhase 3ShionogiNCT01492686Written as MCI-186
- Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS)CompletedPhase 3ShionogiNCT00330681Written as MCI-186
- Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) Who Met Severity Classification IIICompletedPhase 3ShionogiNCT00415519Written as MCI-186
- Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With Amyotrophic Lateral Sclerosis (ALS)CompletedPhase 3ShionogiNCT00424463Written as MCI-186
- Extension Study Following the Studies MT-1186-A03 or A04 to Evaluate the Safety of Oral Edaravone in Subjects With ALSCompletedPhase 3ShionogiNCT05568615Written as MT-1186
- Clinical Pharmacology Study of Oral Edaravone in Amyotrophic Lateral Sclerosis Patients With GastrostomyCompletedPhase 1ShionogiNCT04254913Written as MT-1186
- Safety and Pharmacokinetics of MCI-186 in Subjects With Acute Ischemic StrokeCompletedPhase 2ShionogiNCT00821821Written as MCI-186
- Study of Oral Edaravone in Healthy Adult MalesCompletedPhase 1ShionogiNCT04481750Written as MT-1186
- PK Study in Subjects With Severe Hepatic ImpairmentCompletedPhase 1ShionogiNCT03664544Written as MCI-186
- Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study)CompletedPhase 1ShionogiNCT04481789Written as MT-1186
- Comparative Bioavailability Study of Oral Edaravone Administered Orally and Via a Nasogastric TubeCompletedPhase 1ShionogiNCT04776135Written as MT-1186
- Clinical Pharmacology Study of Oral Edaravone in Patients With Amyotrophic Lateral SclerosisCompletedPhase 1ShionogiNCT04176224Written as MT-1186
- Bioequivalence Study of Oral Suspension and Intravenous Formulation of Edaravone in Healthy Adult SubjectsCompletedPhase 1ShionogiNCT04493281Written as MT-1186
- Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Hepatic ImpairmentCompletedPhase 1ShionogiNCT03289234Written as MCI-186
- Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Renal ImpairmentCompletedPhase 1ShionogiNCT03289208Written as MCI-186
See all 36 studies that test Edaravone →
Given in every arm · 2 — Edaravone is usual care beside what is tested
As the comparator · 3 — what is tested is compared with Edaravone
- Study of Compound Edaravone Injection for Treatment of Acute Ischemic StrokeSuspendedPhase 2Nanjing Yoko Biomedical Co., Ltd.NCT04984577Written as Edaravone Injection
- Study of Compound Edaravone Injection for Treatment of Acute Ischemic StrokeCompletedPhase 3Jiangsu Simcere Pharmaceutical Co., Ltd.NCT02430350Written as Edaravone Injection
- Compound Edaravone Injection for Acute Ischemic StrokeCompletedPhase 2Jiangsu Simcere Pharmaceutical Co., Ltd.NCT01929096Written as Edaravone Injection
Codes
What other systems call Edaravone · ClinicalTrials.gg INT006749
- MeSH (NLM) D000077553EdaravoneConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) S798V6YJRPEDARAVONEConfirmed FDA, NLM, Wikidata
- RxNorm 1921877Confirmed FDA, Wikidata
- Wikidata Q335099edaravoneConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C74323EdaravoneConfirmed FDA, Wikidata
- DrugBank DB12243One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077553 | Edaravone | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | S798V6YJRP | EDARAVONE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1921877 | — | Confirmed FDA, Wikidata |
| Wikidata | Q335099 | edaravone | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C74323 | Edaravone | Confirmed FDA, Wikidata |
| DrugBank | DB12243 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.