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Oppositional Defiant Disorder clinical trials

The registry lists 86 studies for Oppositional Defiant Disorder across more than 10 countries. 16 are recruiting or about to start. 25 of them are mainly about Oppositional Defiant Disorder (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

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Status

Completed
60
Recruiting
13
Status unknown
6
Not yet recruiting
3
Terminated
2
Active, not recruiting
2

Phase

Phase 3
9
Phase 4
7
Phase 1
4
Phase 2
3

Where

United States
39
Germany
8
Sweden
6
Canada
4
Italy
3
Israel
2

Who runs them

Karolinska Institutet (6) · University of Pittsburgh (4) · Centre for Addiction and Mental Health (3) · University of South Florida (3) · Eli Lilly and Company (3) · Janssen Pharmaceutica N.V., Belgium (2) · Mental Health Services in the Capital Region, Denmark (2) · University of Cologne (2)

What is being tested here

Drugs under test in Oppositional Defiant Disorder studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Clonidine101
Risperidone036
Atomoxetine023
Omega-3 fatty acid002
Emoxypine succinate011
Olanzapine001
Aripiprazole001
Guanfacine001
Brexpiprazole001
Valproic Acid001

Drug classes tested here Antipsychotics 7

Coming up

0phase 3 studies under way
8studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 8

Who these studies take

Of the 13 Oppositional Defiant Disorder studies recruiting now, 2 (15%) set no upper age limit and 11 (85%) stop at 75 or younger. 11 (85%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (15%) take healthy volunteers.

Recruiting studies that take each age, of 13
AgeWomenMen
108 (62%)8 (62%)
183 (23%)3 (23%)
302 (15%)2 (15%)
402 (15%)2 (15%)
502 (15%)2 (15%)
652 (15%)2 (15%)
752 (15%)2 (15%)
852 (15%)2 (15%)

Across all 86 studies, recruiting or not: 88% stop at 75 or younger and 88% at 65; 97% take children; 0% are for women only and 3% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Oppositional Defiant Disorder studies take

Of 36 interventional studies with no phase under Oppositional Defiant Disorder, half reached primary completion within 28 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase28 mo19–48 · 36 studies—28 mo19–48 · 35 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

Studies

Recruiting first, then most recently updated. Showing 50 of 86. Browse all 86 → or search them.