Opiate Overdose: all 70 studies

Page 1 of 1. Open to participants first (11), then studies with results posted, then the rest; newest registration first within each.

• A Bundled Intervention to End Opioid OverdosesRecruitingNCT07485335Phase 4
• A Model to Save Lives Through a Volunteer First Responder Service Providing Antidote Treatment in Opioid OverdoseRecruitingNCT07079241Not applicable
• Reducing Overdose and Substance Use-related Stigma by Training Non-substance-using Friends and Family Members of People Who Use Opioids to Be Harm Reduction ChampionsRecruitingNCT06823453Not applicable
• Overdose Recovery and Care Access (ORCA) Qualitative Stakeholder Interviews and County-level DataRecruitingNCT06768814Not applicable
• Serious Game to Teach Opioid Overdose ResponseNot yet recruitingNCT06727786Phase 2
• Evaluation of Clinical Decision Support in Opioid TaperingNot yet recruitingNCT06527079
• UnityPhilly Response App for Overdose ReversalRecruitingNCT06466005Not applicable
• Naloxone for Opioid Associated Out of Hospital Cardiac ArrestNot yet recruitingNCT06251609Phase 2
• Improving Availability of Intranasal NaloxoneRecruitingNCT05877118Not applicable
• Removing Barriers: Community Partnering for Innovative Solutions to the Opioid CrisisRecruitingNCT05665179Not applicable
• Young Houston Emergency Opioid Engagement SystemRecruitingNCT04811014Phase 4
• Pharmacodynamic Evaluation of Intramuscular Nalmefene Autoinjector 1.5 mg Compared to Intranasal Narcan 4 mgCompletedNCT06719986Phase 1Results posted
• THRIVE: Culturally AdapTed Harm Reduction InterventionCompletedNCT06609278Not applicableResults posted
• A Bundled InterventionCompletedNCT06593093Phase 4Results posted
• Opioid Rapid Response System: Naloxone Training in CommunitiesCompletedNCT06238128Not applicableResults posted
• Pharmacokinetic Evaluation of Intranasal Nalmefene Using Three Dosing RegimensCompletedNCT05219669Phase 1Results posted
• Peer Intervention to Link Overdose Survivors to Treatment (PILOT)CompletedNCT05123027Not applicableResults posted
• Vaped Marijuana to Attenuate Naloxone-Precipitated WithdrawalTerminatedNCT05114460Phase 2Results posted
• Preventing Overdose Using Information and Data From the EnvironmentCompletedNCT05096429Not applicableResults posted
• User Acceptability of a Device-Based Opioid Overdose InterventionCompletedNCT04530591Results posted
• The Rhode Island Prescription and Illicit Drug StudyCompletedNCT04372238Not applicableResults posted
• Multi-Center Randomized Controlled Trial of Relay- NYC's Nonfatal Overdose Response ProgramCompletedNCT04317053Not applicableResults posted
• Increasing Naloxone Access for Persons Who Use OpioidsCompletedNCT04303000Phase 4Results posted
• SafetyNet Program for Opioid Use Disorder (OUD)CompletedNCT04253782Not applicableResults posted
• Preventing Opioid Overdose Mortality in the United StatesCompletedNCT03924505Not applicableResults posted
• Project OOPEN: Opioid Overdose Prevention, Education and InterventionCompletedNCT01788306Phase 4Results posted
• Pharmacokinetic (PK) Evaluation of Nalmefene FormulationsCompletedNCT07543276Phase 1
• Quantitative Xylazine Measurement in EDCompletedNCT06949605
• Developing and Evaluating a Machine-Learning Opioid Overdose Prediction & Risk-Stratification Tool in Primary CareActive, not recruitingNCT06810076Not applicable
• Machine-Learning Prediction and Reducing Overdoses With EHR NudgesActive, not recruitingNCT06806163Not applicable
• The Feasibility of Using the PulsePoint to Facilitate Overdose Education and Naloxone DistributionActive, not recruitingNCT06523985Not applicable
• Vending Machine Naloxone Distribution for Your Community (VENDY)Active, not recruitingNCT06429436Phase 4
• Nalmefene vs Naloxone for the Treatment of Recurrent Respiratory Depression After Opioid OverdoseWithdrawnNCT06408714Phase 3
• Clinical Decision Support to Improve System Naloxone Co-prescribingCompletedNCT06271668
• Safety, Tolerability, and Pharmacokinetics of CSX-1004CompletedNCT06005402Phase 1
• Health Insurance Instability and Mortality Among Patients Receiving Bup Tx for OUDActive, not recruitingNCT05944133
• Kentucky Access to Recovery EvaluationCompletedNCT05889702
• Blood Naloxone Levels Following Intradermal Injection in HumansWithdrawnNCT05876572Phase 4
• Clinical Outcomes From NalmefeneWithdrawnNCT05808881Phase 4
• Supporting Treatment Access and Recovery Through Linkage and SupportActive, not recruitingNCT05713695Not applicable
• Tailoring Overdose Education for Black ChurchesWithdrawnNCT05645016Not applicable
• Development of a Tracheal Sound SensorCompletedNCT05506267
• Evaluation of a Novel Intervention to Prevent Polysubstance Overdoses Involving Illicit StimulantsCompletedNCT05493475Not applicable
• Evaluating an Intervention to Prevent Overdoses in Rural and Urban CountiesActive, not recruitingNCT05463341Not applicable
• Pharmacokinetics (PK) and Safety of Multiple Doses of Intranasal Naloxone in Healthy AdultsCompletedNCT05377255Phase 1
• Pharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy VolunteersCompletedNCT05363501Phase 1
• ARM-ED: Advanced Respiratory Monitoring Events in Drug ToxicityCompletedNCT05358132
• More Individualized Care: Assessment and Recovery Through EngagementCompletedNCT05122676Not applicable
• Community and Familial Impacts of the Opioid CrisisCompletedNCT05116852
• Preventing Opioid Overdose Deaths by Empowering Pharmacists to Dispense NaloxoneCompletedNCT05093309Not applicable
• European Cohort Study of the Effectiveness of Take Home NaloxoneStatus unknownNCT05072249
• Opioids and Police Safety StudyStatus unknownNCT05008523Not applicable
• Ultrasound-guided PENG Block in Total Hip ReplacementCompletedNCT04984109Not applicable
• Naloxone Education in Total Joint PatientsStatus unknownNCT04868552Not applicable
• Extended-release Injectable Buprenorphine for Individuals at High Risk of OverdoseStatus unknownNCT04815590
• Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER)WithdrawnNCT04740099Not applicable
• A Single-Dose, Bioequivalence Study of FMXIN001 4 mg Microspheres PowderCompletedNCT04713709Phase 1
• Developing and Testing the Opioid Rapid Response SystemCompletedNCT04589676Not applicable
• Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory DepressionCompletedNCT04301895Phase 1
• Patient Reported Outcomes for Opioid Use DisorderCompletedNCT03985163
• Measures to Improve Outcomes After an Opioid OverdoseWithdrawnNCT03968237
• Recovery Initiation and Management After Overdose (RIMO) ExperimentCompletedNCT03895827Not applicable
• Development of an Algorithm That Predicts Hypoventilation Due to an Opioid OverdoseStatus unknownNCT03845699
• FAVOR Opioid Recovery Coaching EvaluationCompletedNCT03798470Not applicable
• Naloxone Treatment in Skåne County - Effect on Drug-related Mortality and Overdose-related ComplicationsStatus unknownNCT03570099
• Rapid Self-Testing to Prevent Fentanyl Overdose Among Young People Who Use DrugsCompletedNCT03373825Not applicable
• Piloting a Naloxone Intervention in PhiladelphiaCompletedNCT03305497
• Incidence and Predictors of Opioid Overdose and Death Among Long-Term Users of Opioid AnalgesicsCompletedNCT02662153
• Risks and Benefits of Naloxone PrescribingCompletedNCT02535494Not applicable
• Naloxone Nasal Spray Pharmacokinetic StudyStatus unknownNCT01622504Phase 1

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