Essential Tremor clinical trials
The registry lists 261 studies for Essential Tremor across more than 10 countries. 74 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-23.
Status
- Completed
- 126
- Recruiting
- 57
- Status unknown
- 23
- Terminated
- 16
- Not yet recruiting
- 11
- Withdrawn
- 11
Phase
- Phase 2
- 38
- Phase 1
- 14
- Phase 3
- 10
- Phase 4
- 5
- Early Phase 1
- 4
Where
- United States
- 138
- Canada
- 22
- France
- 20
- Spain
- 11
- Germany
- 11
- China
- 11
Who runs them
InSightec (13) · National Institute of Neurological Disorders and Stroke (NINDS) (12) · University of Florida (11) · Mayo Clinic (8) · Cala Health, Inc. (5) · KU Leuven (5) · University of Texas Southwestern Medical Center (5) · University Hospital, Bordeaux (5)
Studies
Recruiting first, then most recently updated. Showing 50 of 261 — search for more.
- Magnetoencephalography (MEG) Pilot StudyRecruitingNCT07446192Not applicable1 country
- Phenotype/Genotype Correlations in Movement DisordersRecruitingNCT000188891 country
- Deep Brain Stimulation Therapy in Movement DisordersRecruitingNCT02119611Not applicable1 country
- Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor FunctionRecruitingNCT07056348Not applicable1 country
- Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle ControlRecruitingNCT07056361Not applicable1 country
- Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's DiseaseRecruitingNCT074284471 country
- Stereotactic Radiosurgery for Essential Tremor and Parkinsonian TremorRecruitingNCT017341221 country
- Effects of Microelectrode-based Brain Stimulation in HumansNot yet recruitingNCT07820189Not applicable1 country
- Neurofeedback Using Implanted Deep Brain Stimulation ElectrodesRecruitingNCT05101161Not applicable1 country
- Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNSRecruitingNCT065536252 countries
- Boston Scientific Registry of Deep Brain Stimulation for Treatment of Essential Tremor (ET)RecruitingNCT040324709 countries
- 3-D Tractography FUS Ablation for Essential TremorRecruitingNCT06331052Not applicable1 country
- Deep Brain Stimulation (DBS) Retrospective Outcomes StudyRecruitingNCT036646096 countries
- Deep Brain Stimulation Surgery for Movement DisordersRecruitingNCT01581580Not applicable1 country
- EMBRACE Tremor BiFUSRecruitingNCT06974916Not applicable7 countries
- Physiological Brain Atlas DevelopmentRecruitingNCT005750811 country
- Non-Invasive Neuromodulation for Essential Tremor: Long-Term Safety and Effectiveness StudyRecruitingNCT07774598Not applicable1 country
- LIFUS For Neurological DisordersRecruitingNCT07417280Not applicable1 country
- Image-Guided DBS ProgrammingNot yet recruitingNCT07433699Not applicable1 country
- Circadian Adaptive DBS in Essential TremorRecruitingNCT06635811Not applicable1 country
- Human Cognition During Surgery: Stimulation-based and Cholinergic ModulationNot yet recruitingNCT07721272Early Phase 11 country
- Motor Network PhysiologyRecruitingNCT04957095Not applicable1 country
- Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory TremorRecruitingNCT07049003Phase 11 country
- Coordinated Reset Deep Brain Stimulation for Essential TremorRecruitingNCT05897775Phase 11 country
- Open Label Study for the Use of Low Intensity Focused Ultrasound for Essential TremorRecruitingNCT07599592Early Phase 11 country
- Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential TremorRecruitingNCT062936381 country
- Closed-loop TMS for TremorRecruitingNCT07574164Not applicable1 country
- Attention and Eye Movement in Parkinson's DiseaseRecruitingNCT06899022Not applicable1 country
- Transcranial Temporal Interference Stimulation (tTIS) To Modulate Essential TremorNot yet recruitingNCT07531238Not applicable1 country
- Effects of Stimulation Patterns of Deep Brain StimulationEnrolling by invitationNCT02553525Not applicable1 country
- Cerebellar Research in Ultrasound StimulationNot yet recruitingNCT07508696Not applicable1 country
- Cortical-Basal Ganglia Speech NetworksRecruitingNCT04286308Not applicable1 country
- Motor and Non-Motor Effects of Low-Intensity Focused Ultrasound (LIFU) as a Neuromodulation Tool in Essential TremorNot yet recruitingNCT07484152Phase 1/2
- Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator RecipientsRecruitingNCT07455760Not applicable1 country
- Ultrasound Neuromodulation in Essential TremorRecruitingNCT06610877Not applicable1 country
- ET Stigma Response to Tremor SuppressionRecruitingNCT074307611 country
- Dual Lead Thalamic Deep Brain Recording (DBR)-DBS Interface for Closed Loop Control of Severe Essential TremorRecruitingNCT04212780Not applicable1 country
- Algorithms for Programming DBS Systems for ETRecruitingNCT03984643Not applicable1 country
- Dual-Site Transcranial Magnetic Stimulation of the Supplementary Motor Area and Cerebellum for the Treatment of Essential Tremor.RecruitingNCT07344194Phase 1/21 country
- Abbott DBS Post-Market Study of Outcomes for Indications Over TimeRecruitingNCT040718479 countries
- Neuromodulation Strategies for Treatment-Resistant Essential Tremor Using Chronos™ DBSNot yet recruitingNCT07302867Not applicable1 country
- Proof of Concept Study on BP1.4979 Effect on Essential TremorRecruitingNCT07074002Phase 21 country
- Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated DystoniaRecruitingNCT05317390Not applicable1 country
- Home Use Study of Targeted Mechanical Stimulation for Tremor ReliefRecruitingNCT07078422Not applicable1 country
- The Efficacy of Aldehyde Dehydrogenase Enzyme in Essential Tremor Patients: A Single-Center StudyEnrolling by invitationNCT07238725Not applicable1 country
- Directional Versus Nondirectional DBS for ETRecruitingNCT04828798Not applicable1 country
- A Study of Wearable Device in Essential Tremor PatientsEnrolling by invitationNCT05976074Not applicable1 country
- Analysis of Clinical Outcomes in Patients Undergoing Magnetic Resonance-Guided Focused Ultrasound for Medication-Refractory TremorRecruitingNCT072122441 country
- Identifying Markers of Disease Subtypes and Disease Progression in the Syndrome of Essential TremorEnrolling by invitationNCT063495381 country
- Modulate Tremor Severity With Low-intensity Focused Ultrasound Stimulation Targeting the Deep Nucleus of Patients With Refractory Hand Tremor.RecruitingNCT07172295Not applicable1 country