Dystonic Disorders clinical trials
The registry lists 95 studies for Dystonic Disorders across more than 10 countries. 19 are recruiting or about to start. 46 of them are mainly about Dystonic Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its narrower condition Dystonia, Focal, Task-Specific too: 103 studies, 21 open.
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Who runs them
National Institute of Neurological Disorders and Stroke (NINDS) (33) · Fondation Ophtalmologique Adolphe de Rothschild (5) · University of Texas Southwestern Medical Center (2) · Vima Therapeutics (2) · University Hospital, Lille (2) · University of Minnesota (2) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (2) · Boston Children's Hospital (2)
What is being tested here
Drugs under test in Dystonic Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Dec 2026Effects of Neuromodulation in Laryngeal Dystonia · MGH Institute of Health Professions
- Feb 2027Focused Ultrasound Unilateral Pallidotomy for Medication-Refractory Limb Dystonia · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
- Mar 2027A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia · Vima Therapeutics
- Jun 2027Neurosurgical Outcome Network · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
- Sep 2027Dystonia Genotype-Phenotype Correlation · University of Texas Southwestern Medical Center
Who these studies take
Of the 17 Dystonic Disorders studies recruiting now, 4 (24%) set no upper age limit and 6 (35%) stop at 75 or younger. 6 (35%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (29%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (29%) | 5 (29%) |
| 18 | 13 (76%) | 13 (76%) |
| 30 | 14 (82%) | 14 (82%) |
| 40 | 13 (76%) | 13 (76%) |
| 50 | 13 (76%) | 13 (76%) |
| 65 | 13 (76%) | 13 (76%) |
| 75 | 12 (71%) | 12 (71%) |
| 85 | 7 (41%) | 7 (41%) |
Across all 95 studies, recruiting or not: 36% stop at 75 or younger and 21% at 65; 29% take children; 0% are for women only and 1% for men only; 34% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered2
- Protocol in Musician's Focal Dystonia (MISA)Nov 6, 2026NCT07923799
- VTS Sensorimotor Neuromodulation in WCOct 26, 2026NCT07894198
Studies
Recruiting first, then most recently updated. Showing 50 of 95. Browse all 95 → or search them.
- Impact of rTMS on Abnormal Cortical fMRI in Patients With DystoniaRecruitingNCT07626216Not applicable1 country
- Focused Ultrasound Unilateral Pallidotomy for Medication-Refractory Limb DystoniaRecruitingNCT07168850Not applicable1 country
- VTS Sensorimotor Neuromodulation in WCNot yet recruitingNCT07894198Not applicable
- A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated DystoniaRecruitingNCT07304089Phase 22 countries
- Dystonia Genotype-Phenotype CorrelationRecruitingNCT034280091 country
- Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral PalsyRecruitingNCT06554288Phase 11 country
- Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult SubjectsRecruitingNCT06036199Not applicable1 country
- Attention and Eye Movement in Parkinson's DiseaseRecruitingNCT06899022Not applicable1 country
- Neurosurgical Outcome NetworkRecruitingNCT067240291 country
- A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia SyndromesRecruitingNCT065856051 country
- Effects of Neuromodulation in Laryngeal DystoniaRecruitingNCT05095740Not applicable1 country
- Abbott DBS Post-Market Study of Outcomes for Indications Over TimeRecruitingNCT040718479 countries
- Local Field Potentials in DystoniaRecruitingNCT073091331 country
- Brain Networks in DystoniaRecruitingNCT030429621 country
- Registry and Natural History of Epilepsy-Dyskinesia SyndromesRecruitingNCT069677271 country
- Video-supervised Motor and Awareness Training in Writer's CrampRecruitingNCT04611009Phase 21 country
- Heart Rate Variability Biofeedback Training in Psychogenic DisordersRecruitingNCT04777825Not applicable1 country
- Sensorimotor Integration in Monogenic Parkinson-dystonia SyndromesRecruitingNCT057137211 country
- Enhancing Sensorimotor Processing in Children With DystoniaNot yet recruitingNCT05612464
- Cholinergic Receptor Imaging in DystoniaCompletedNCT026894661 country
- Deep Brain Stimulation Surgery for Focal Hand DystoniaActive, not recruitingNCT02911103Phase 1/21 country
- Protocol in Musician's Focal Dystonia (MISA)CompletedNCT079237991 country
- An Observational Study of Individuals With Isolated DystoniaActive, not recruitingNCT071116631 country
- Agency in DystoniaCompletedNCT03351218Not applicable1 country
- Stimulation of the Dentate Nucleus of the Cerebellum for the Treatment of Refractory Spasticity With or Without DystoniaCompletedNCT07231302
- Propensity to Develop Plasticity in the Parieto-Motor Networks in Dystonia From the Perspective of Abnormal High-Order Motor ProcessingCompletedNCT02504905Early Phase 11 country
- İnvestigating Dysphagia in Pediatric DystoniaActive, not recruitingNCT068157571 country
- An Open-label Study to Define the Safety, Tolerability and Clinical Activity of Deutetrabenazine (AUstedo) in Adult Study Subjects With DYsToniaCompletedNCT04173260Phase 1/21 country
- Assessment of Long-term Clinical Response to BoNT in Cervical DystoniaCompletedNCT058845281 country
- Description of the Evolution of Functional Dysphonia Managed by HypnotherapyTerminatedNCT051798111 country
- The Effect of Dystonia Severity on Participation in Daily Living Activities and Caregivers in Children of Cerebral Palsy With Secondary DystoniaCompletedNCT063075611 country
- Electrophysiological and Neuroimaging Correlates of the Effect of Zolpidem in Patients With Focal DystoniaCompletedNCT04692285Phase 12 countries
- Effect of the Visual Information Change in Functional DystoniaTerminatedNCT03270189Not applicable1 country
- Using Wearable and Mobile Data to Diagnose and Monitor Movement DisordersStatus unknownNCT042314871 country
- Neuropathology of Spasmodic DysphoniaCompletedNCT001185861 country
- Botulinum Toxin Type A for Foot Dystonia-associated Pain in Parkinson's DiseaseStatus unknownNCT04277247Phase 2/31 country
- Validation of the Zigzag Tracking Task Test for the Evaluation of Handwriting Difficulties in Writer's CrampTerminatedNCT028822951 country
- Movement Disorders and Early Maladaptive SchemasCompletedNCT037173761 country
- Compare Two Guidance Techniques for Botulinum Toxin Injections for the Treatment of Limb Spasticity and Focal DystoniaCompletedNCT02334683Not applicable1 country
- Excessive Crying in Children With Cerebral Palsy and Communication DeficitsCompletedNCT04523935Phase 4
- Oral Zinc Supplementation to Enhance Botulinum Neurotoxin ResponseCompletedNCT05095493Not applicable
- Finger Individuation Training With a Training Device Versus Conventional Rehabilitation for Writer's CrampTerminatedNCT02882334Not applicable1 country
- Characterization of Manual Dexterity by Finger Force Manipuladum (FFM) in Patients With Writer's Cramp and in Control SubjectsCompletedNCT03797638Not applicable1 country
- Precision-targeted Transcranial Magnetic Stimulation in the Treatment of Primary DystoniaStatus unknownNCT04727177Early Phase 11 country
- Multi-Target Pallidal and Thalamic Deep Brain Stimulation for Hemi-DystoniaStatus unknownNCT02982304Phase 11 country
- Motor and Non-motor Symptoms in Cervical DystoniaStatus unknownNCT045601011 country
- Loss of Depotentiation in Focal DystoniaTerminatedNCT032061121 country
- Non-Motor Features of Cervical Dystonia (CD)CompletedNCT034719231 country
- Long-Term Motor Learning in Focal Hand DystoniaCompletedNCT003250911 country
- Brain Changes in BlepharospasmTerminatedNCT004873831 country