Meningitis clinical trials
The registry lists 268 studies for Meningitis across more than 10 countries. 28 are recruiting or about to start. 91 of them are mainly about Meningitis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 4 narrower conditions too, such as Meningitis, Meningococcal: 431 studies, 58 open.
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Who runs them
Sanofi Pasteur, a Sanofi Company (40) · Novartis Vaccines (24) · GlaxoSmithKline (16) · Pfizer (14) · National Institute of Allergy and Infectious Diseases (NIAID) (6) · Novartis (4) · Assistance Publique - Hôpitaux de Paris (4) · University of Oxford (4)
What is being tested here
Drugs under test in Meningitis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Dec 2026Acute Treatment and Long-term Assessment of Adult Infectious Meningitis · Hospital Israelita Albert Einstein
- Dec 2026Prospective Clinical Registry of Acute Treatment and Long-term Assessment of Children Meningitis · Hospital Israelita Albert Einstein
- Dec 2026Neuroendoscopic Surgery With Ommaya Reservoir Implantation vs. Burr Hole Drainage for Infantile Postmeningitis Subdural Lesions: Superior Efficacy, Critical Impact of Surgical Timing, and Pathogenic Bacteria as Risk Factors for Progression · Shengjing Hospital
- Jun 2027Hemorrhage Elimination During Lumbar Puncture Using Ultrasound Measurements (HELPUS) · Vanderbilt University Medical Center
- Aug 2027Clinical Characteristics and Prognostic Factors in Patients With Meningitis at Sohag Governorate. · Sohag University
- Nov 2027Adjunctive Doxycycline for Central Nervous System Tuberculosis · National University Hospital, Singapore
Who these studies take
Of the 17 Meningitis studies recruiting now, 11 (65%) set no upper age limit and 6 (35%) stop at 75 or younger. 7 (41%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (12%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (35%) | 6 (35%) |
| 18 | 14 (82%) | 14 (82%) |
| 30 | 13 (76%) | 13 (76%) |
| 40 | 13 (76%) | 13 (76%) |
| 50 | 13 (76%) | 13 (76%) |
| 65 | 12 (71%) | 12 (71%) |
| 75 | 12 (71%) | 12 (71%) |
| 85 | 11 (65%) | 11 (65%) |
Across all 268 studies, recruiting or not: 59% stop at 75 or younger and 57% at 65; 69% take children; 3% are for women only and 1% for men only; 50% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Meningitis studies take
Of 19 phase 3 interventional studies under Meningitis, half reached primary completion within 15 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 10 mo5–18 · 13 studies | — | — |
| Phase 3 | 15 mo7–28 · 19 studies | — | — |
| Interventional, no phase | 28 mo10–34 · 24 studies | — | — |
| Observational | 33 mo15–96 · 29 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Results posted1
Newly registered1
- A Pivotal Safety and Immunogenicity GBS-NN/NN2 Vaccine Maternal Immunisation TrialNov 6, 2026NCT07922226
Studies
Recruiting first, then most recently updated. Showing 50 of 268. Browse all 268 → or search them.
- A Pivotal Safety and Immunogenicity GBS-NN/NN2 Vaccine Maternal Immunisation TrialNot yet recruitingNCT07922226Phase 2/3
- Acute Treatment and Long-term Assessment of Adult Infectious MeningitisRecruitingNCT070274751 country
- Aciclovir Versus Placebo for HSV-2 MeningitisNot yet recruitingNCT05452928Phase 4
- BPaLMZ for TB MeningitisRecruitingNCT07227779Phase 21 country
- THiamine for Recovery In Vulnerable Early-life InfectionsNot yet recruitingNCT07868679Phase 21 country
- Group-based Emotional Awareness and Expression Therapy to Support Recovery After Acquired Brain Injury: A Clinical Development and Evaluation StudyRecruitingNCT07852936Not applicable1 country
- Meningitis: Burden, Causes, Screening and Prevention in Rural Northern UgandaRecruitingNCT05496673Not applicable1 country
- Prediction of Infectious Agents in the Biofire® FilmArray bioMérieux Meningitis/Encephalitis Panel Based on Clinical Syndrome and Cerebrospinal Fluid Parameters: a Diagnostic Stewardship Proposal.RecruitingNCT07432113Not applicable1 country
- Clinical Characteristics and Prognostic Factors in Patients With Meningitis at Sohag Governorate.Not yet recruitingNCT077689821 country
- Immune-Mitochondrial Correction in Military RecruitsNot yet recruitingNCT07622147Not applicable
- Regulating Emotions and Behaviors After Brain InjuryRecruitingNCT05393492Not applicable1 country
- Recovery Trajectory for Coma and Disorders of ConsciousnessRecruitingNCT076140741 country
- Adjunctive Doxycycline for Central Nervous System TuberculosisRecruitingNCT06446245Phase 23 countries
- Hemorrhage Elimination During Lumbar Puncture Using Ultrasound Measurements (HELPUS)RecruitingNCT07612644Not applicable1 country
- Prospective Clinical Registry of Acute Treatment and Long-term Assessment of Children MeningitisRecruitingNCT070624451 country
- National Bacterial Meningitis Study in Children and NewbornsRecruitingNCT046645691 country
- Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health PerspectiveRecruitingNCT073589101 country
- Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral PathologiesRecruitingNCT073322341 country
- Neuroendoscopic Surgery With Ommaya Reservoir Implantation vs. Burr Hole Drainage for Infantile Postmeningitis Subdural Lesions: Superior Efficacy, Critical Impact of Surgical Timing, and Pathogenic Bacteria as Risk Factors for ProgressionNot yet recruitingNCT07320599
- Evolving Diagnostic Approaches to Undocumented Lymphocytic Meningitis and MeningoencephalitisEnrolling by invitationNCT071868811 country
- Bedside Ultrasound on the Effectiveness of Lumbar Puncture in Children.RecruitingNCT06584864Not applicable1 country
- Causes of Secondary and Prolonged Fever During Treatment of Bacterial Meningitis and Viral EncephalitisNot yet recruitingNCT06971133
- Neonatal Comfort Seat Allowing Safe Lumbar Puncture and Minimizing Failure: a Randomized Controlled TrialNot yet recruitingNCT06811428Not applicable
- Phase II Clinical Study of Contezolid for the Treatment of Tuberculous MeningitisEnrolling by invitationNCT06811025Phase 1/21 country
- Central Nervous System Infections in DenmarkRecruitingNCT034184411 country
- Improving Diagnosis and Prediction of Outcome in Patients With Severe Disorders of ConsciousnessRecruitingNCT062839011 country
- Lebanese Interhospital Pneumococcal Surveillance ProgramRecruitingNCT009016021 country
- Establishment of Prevention and Control System of Central Nervous System InfectionNot yet recruitingNCT047223281 country
- A Phase 3 Study to Assess the Immune Response and Safety of rMenB+OMV NZ in Primed Healthy Participants (10 to 20 Years Old)CompletedNCT06995430Phase 34 countries
- Impact of a PCT(Procalcitonin) Rapid Test -Based Approach on ATB (Antibiotics) Use in Children With Fever Without SourceCompletedNCT03607162Not applicable2 countries
- A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant WomenActive, not recruitingNCT06592586Phase 2/32 countries
- Safety and Immunogenicity of GSK Meningococcal Group B Vaccine and 13-valent Pneumococcal Vaccine Administered Concomitantly With Routine Infant Vaccines to Healthy InfantsCompletedNCT03621670Phase 32 countries
- MUSic Therapy In Complex Specialist NeurorehabilitationCompletedNCT05777499Not applicable1 country
- Clinical Performance of QIAstat-Dx® Meningitis/Encephalitis (ME) Panel PlusActive, not recruitingNCT068200601 country
- Understanding the Immune Response to Two Different Meningitis VaccinesCompletedNCT01593514Phase 41 country
- A Study on the Immune Response and Safety of a Vaccine Against N. Meningitidis Serogroup B Infection in Healthy Infants From 2 Months of AgeActive, not recruitingNCT06113198Phase 41 country
- Meningococcal Serogroup ACYWX Conjugate Vaccine in Comparison With MenACWY-TT Conjugate VaccineCompletedNCT05093829Phase 31 country
- Molecular Panel Evaluation for Diagnosis of Infections of the Central Nervosous SystemCompletedNCT067205191 country
- Evaluation of New Biomarker-based Approaches for Improving the Diagnosis of Childhood Tuberculous MeningitisCompletedNCT043089281 country
- Primary Immunodeficiencies and Obstetrical Neuraxial AnaesthesiaCompletedNCT064490661 country
- Integrative Approach to Identify Environmental Risk Factors for CC-17 Group B Streptococcal Neonatal InfectionCompletedNCT02471937Not applicable1 country
- Interest of the Detection of Hyper-virulent Clone ST17 of Group B Strep (GBS) for the Prevention of Neonatal GBS MeningitisCompletedNCT01719510Not applicable1 country
- Risk Factors and Outcomes in Patients Treated in Neurocritical CareCompletedNCT070526561 country
- Analysis of Cerebrospinal Fluid in Patients With Cerebral Toxoplasmosis at CHSD (2004-2024)CompletedNCT070440371 country
- A Study to Evaluate Safety and Immunogenicity of Haemophilus Influenzae Serotype A VaccineActive, not recruitingNCT06465420Phase 11 country
- QIAstat-Dx® Meningitis/Encephalitis Panel Performance Evaluation Study 001CompletedNCT050924381 country
- A Human Controlled Infection Study with Neisseria Lactamica in Malian AdultsCompletedNCT04665791Not applicable1 country
- Study to Assess the Safety and Immunogenicity of GSK Meningococcal Group B Vaccine When Administered Concomitantly With GSK Meningococcal MenACWY Conjugate Vaccine in Healthy Subjects of 16-18 Years of AgeCompletedNCT04318548Phase 32 countries
- BIGlobal Intervention Study: Improving Diagnosis and Management of Suspected Brain Infections GloballyCompletedNCT041903033 countries
- Infections of the Central Nervous SystemWithdrawnNCT038565281 country