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CompletedNCT07907081Updated Nov 4, 2026

Comparative Analysis of Chamomile Tea (Matricaria Chamomilla) and Green Tea (Camellia Sinensis) Against Hyperlipidemia

An interventional study of Chamomile tea (Matricaria chamomilla) and Green tea (Camellia sinensis) in Hyperlipidemia and Normal, sponsored by Iahtisham-Ul-Haq. Completed at 1 site in Pakistan. Open to male participants, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-04.

Sponsored by Iahtisham-Ul-Haq · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 7 years 11 months after the study started (first participant enrolled Nov 2018, registered Oct 2026).
Updated Nov 4, 2026Primary outcomes revisedInterventions changed+1 moreGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
25
Allocation
Randomized
Sex
Male
01

Study summary

Present study was conducted to compare the efficacy of green tea (Camellia sinensis) and chamomile tea (Matricaria chamomilla), administered individually, as a combined intervention, and as a sequential (morning/evening) regimen on glycemic, lipid, hepatic, and renal biomarkers in normal and hyperlipidemic subjects. Two parallel studies were conducted: Study I assessed the effects of intervention on normal subjects while Study II assessed the effect in hyperlipidemic subjects. Both studies consisted of an untreated control group and four tea-based intervention groups. The biochemical parameters including fasting blood glucose (FBG), low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), high-density lipoprotein (HDL), triglycerides (TG), total cholesterol (TC), aspartate aminotransferase (AST), alkaline phosphatase (ALP), alanine aminotransferase (ALT), bilirubin, urea, and creatinine were measured at baseline (Day 1) and after 30 days of intervention.

02

Conditions studied

  • Hyperlipidemia
  • Normal

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03

In context

Hyperlipidemias

841 studies on the registry are indexed under Hyperlipidemias; 108 are open to participants now.

This study's enrollment of 25 is below the median of 88 across 709 interventional studies indexed under Hyperlipidemias.

Browse Hyperlipidemias studies →

Lead sponsor

This is the only study on the registry with Iahtisham-Ul-Haq as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
Male
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Individuals with Hyperlipidemia with with no preexisting disorders like diabetes or history of drug abuse were selected for study II.

Exclusion criteria

Exclusion Criteria:

  • Individuals diagnosed with a chronic disease, mental or physical illness, and smokers were excluded from the trial.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
25 participants (actual)

Study arms

  • Experimental
    Green tea - Normal subjects

    Normal subjects who prepared and drank 200 ml of green tea per day for 30 days

    Other: Green tea (Camellia sinensis)

  • Experimental
    Chamomile tea - Normal subjects

    Normal subjects who prepared and drank 200 ml of chamomile tea per day for 30 days

    Other: Chamomile tea (Matricaria chamomilla)

  • Experimental
    Chamomile tea and Green tea Combined - Normal subjects

    Normal subjects who prepared and drank a mixed tea of 100 ml green tea and 100 ml of chamomile tea per day for 30 days

    Other: Chamomile tea (Matricaria chamomilla) · Other: Green tea (Camellia sinensis)

  • Experimental
    Green tea (morning) and Chamomile tea (evening) - Normal subjects

    Normal subjects who prepared and drank 100 ml of green tea in the morning and 100 ml of chamomile tea in the evening per day for 30 days

    Other: Chamomile tea (Matricaria chamomilla) · Other: Green tea (Camellia sinensis)

  • No intervention
    Control - Normal subjects

    Normal subjects who did not drink any tea

  • Experimental
    Green tea - Hyperlipidemic patients

    Hyperlipidemic patients who prepared and drank 200 ml of green tea per day for 30 days

    Other: Green tea (Camellia sinensis)

  • Experimental
    Chamomile tea - Hyperlipidemic patients

    Hyperlipidemic patients who prepared and drank 200 ml of chamomile tea per day for 30 days

    Other: Chamomile tea (Matricaria chamomilla)

  • Experimental
    Chamomile tea and Green tea Combined - Hyperlipidemic patients

    Hyperlipidemic patients who prepared and drank a mixed tea of 100 ml of green tea and 100 ml of chamomile tea per day for 30 days

    Other: Chamomile tea (Matricaria chamomilla) · Other: Green tea (Camellia sinensis)

  • Experimental
    Green tea (morning) and Chamomile tea (evening) - Hyperlipidemic patients

    Hyperlipidemic patients who prepared and drank 100 ml of green tea in the morning and 100 ml of chamomile tea in the evening per day for 30 days

    Other: Chamomile tea (Matricaria chamomilla) · Other: Green tea (Camellia sinensis)

  • No intervention
    Control - Hyperlipidemic patients

    Hyperlipidemic patients who did not drink any tea

Interventions

  • OtherChamomile tea (Matricaria chamomilla)

    Chamomile tea (200 ml) per day for 30 days/ Chamomile tea (100 ml) and Green tea (100 ml) combined per day for 30 days/ Green tea (100 ml) in the morning and Chamomile tea (100 ml) in the evening per day for 30 days

  • OtherGreen tea (Camellia sinensis)

    Green tea (200 ml) per day for 30 days/ Chamomile tea (100 ml) and Green tea (100 ml) combined per day for 30 days/ Green tea (100 ml) in the morning and Chamomile tea (100 ml) in the evening per day for 30 days

06

What researchers measure

Primary outcomes

  1. Serum Low-density lipoprotein (LDL) cholesterol concentration (milligrams per deciliter)

    LDL was measured according to enzymatic reactions in serum or plasma by using Hitachi 704 analyzer serviced by Roche diagnostics

    Time frame: Baseline and 30 days

  2. Serum High-density lipoprotein (HDL) cholesterol concentration (milligrams per deciliter)

    HDL was measured according to enzymatic reactions in serum or plasma by using Hitachi 704 analyzer serviced by Roche diagnostics

    Time frame: Baseline and 30 days

  3. Serum Very low-density lipoprotein (VLDL) cholesterol concentration (milligrams per deciliter)

    VLDL was measured according to enzymatic reactions in serum or plasma by using Hitachi 704 analyzer serviced by Roche diagnostics

    Time frame: Baseline and 30 days

  4. Serum total cholesterol concentration (milligrams per deciliter)

    Total cholesterol was measured according to enzymatic reactions in serum or plasma by using Hitachi 704 analyzer serviced by Roche diagnostics.

    Time frame: Baseline and 30 days

  5. Serum triglycerides concentration (milligrams per deciliter)

    Triglycerides were measured according to enzymatic reactions in serum or plasma by using Hitachi 704 analyzer serviced by Roche diagnostics

    Time frame: Baseline and 30 days

Secondary outcomes

  1. Fasting Blood Glucose concentration (milligrams per deciliter)

    Fasting Blood Glucose was measured by using enzymatic method in Roche Modular P chemistry analyzer

    Time frame: Baseline and 30 days

  2. Serum alanine aminotransferase (ALT) concentration (milligrams per deciliter)

    ALT was measured by using Hitachi 704 analyzer serviced by Roche diagnostics

    Time frame: Baseline and 30 days

  3. Serum aspartate aminotransferase (AST) concentration (milligrams per deciliter)

    AST was measured by using Hitachi 704 analyzer serviced by Roche diagnostics

    Time frame: Baseline and 30 days

  4. Serum alkaline phosphatase (ALP) concentration (milligrams per deciliter)

    ALP was measured by using Hitachi 704 analyzer serviced by Roche diagnostics

    Time frame: Baseline and 30 days

  5. Serum bilirubin concentration (milligrams per deciliter)

    Bilirubin was measured by using Hitachi 704 analyzer serviced by Roche diagnostics

    Time frame: Baseline and 30 days

  6. Serum urea concentration (milligrams per deciliter)

    Urea was analyzed with refrigerated serum in Beckman Synchron LX20

    Time frame: Baseline and 30 days

  7. Serum creatinine concentration (milligrams per deciliter)

    Creatinine was analyzed with refrigerated serum in Beckman Synchron LX20

    Time frame: Baseline and 30 days

07

Study locations

1 site
  • Imperial College of Business Studies
    Lahore, Punjab Province, Pakistan
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

2 registry updates since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Nov 2018 to primary completion in Mar 2019, 4 months.

Of 162 non-industry interventional studies with no phase under Hyperlipidemias, half reached primary completion within 16 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 31. This study's 4 months is below that.

Counting every sponsor, half of 166 studies reached it within 16 months; a quarter within 7 and three quarters within 31.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 25, 2026
First posted
Oct 30, 2026
StartActual
Nov 12, 2018
Primary completionActual
Mar 15, 2019
CompletionActual
Mar 15, 2019
Last update
Nov 4, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Interventions
Removed Chamomile tea and Green tea combined·Green tea (morning) and Chamomile tea (evening)
Nov 4, 2026
Primary outcomes
5 edited
What changed in the outcomes
  • ChangedBefore LDLNow Serum Low-density lipoprotein (LDL) cholesterol concentration (milligrams per deciliter)Time frame: Baseline and 30 days
  • ChangedBefore HDLNow Serum High-density lipoprotein (HDL) cholesterol concentration (milligrams per deciliter)Time frame: Baseline and 30 days
  • ChangedBefore VLDLNow Serum Very low-density lipoprotein (VLDL) cholesterol concentration (milligrams per deciliter)Time frame: Baseline and 30 days
  • ChangedBefore Total cholesterolNow Serum total cholesterol concentration (milligrams per deciliter)Time frame: Baseline and 30 days
  • ChangedBefore TriglyceridesNow Serum triglycerides concentration (milligrams per deciliter)Time frame: Baseline and 30 days
Nov 4, 2026
Secondary outcomes
7 edited
What changed in the outcomes
  • EditedFasting Blood Glucose concentration (milligrams per deciliter)Time frame: Baseline and 30 days
  • ChangedBefore ALTNow Serum alanine aminotransferase (ALT) concentration (milligrams per deciliter)Time frame: Baseline and 30 days
  • ChangedBefore ASTNow Serum aspartate aminotransferase (AST) concentration (milligrams per deciliter)Time frame: Baseline and 30 days
  • ChangedBefore ALPNow Serum alkaline phosphatase (ALP) concentration (milligrams per deciliter)Time frame: Baseline and 30 days
  • ChangedBefore BilirubinNow Serum bilirubin concentration (milligrams per deciliter)Time frame: Baseline and 30 days
  • ChangedBefore UreaNow Serum urea concentration (milligrams per deciliter)Time frame: Baseline and 30 days
  • ChangedBefore CreatinineNow Serum creatinine concentration (milligrams per deciliter)Time frame: Baseline and 30 days
Nov 4, 2026
Registered
First appeared on the registry
Oct 30, 2026
Show all 2 updates
  1. Nov 4, 2026
    Primary outcomes 5 edited
    What changed in the outcomes
    • ChangedBefore LDLNow Serum Low-density lipoprotein (LDL) cholesterol concentration (milligrams per deciliter)Time frame: Baseline and 30 days
    • ChangedBefore HDLNow Serum High-density lipoprotein (HDL) cholesterol concentration (milligrams per deciliter)Time frame: Baseline and 30 days
    • ChangedBefore VLDLNow Serum Very low-density lipoprotein (VLDL) cholesterol concentration (milligrams per deciliter)Time frame: Baseline and 30 days
    • ChangedBefore Total cholesterolNow Serum total cholesterol concentration (milligrams per deciliter)Time frame: Baseline and 30 days
    • ChangedBefore TriglyceridesNow Serum triglycerides concentration (milligrams per deciliter)Time frame: Baseline and 30 days
    Secondary outcomes 7 edited
    What changed in the outcomes
    • EditedFasting Blood Glucose concentration (milligrams per deciliter)Time frame: Baseline and 30 days
    • ChangedBefore ALTNow Serum alanine aminotransferase (ALT) concentration (milligrams per deciliter)Time frame: Baseline and 30 days
    • ChangedBefore ASTNow Serum aspartate aminotransferase (AST) concentration (milligrams per deciliter)Time frame: Baseline and 30 days
    • ChangedBefore ALPNow Serum alkaline phosphatase (ALP) concentration (milligrams per deciliter)Time frame: Baseline and 30 days
    • ChangedBefore BilirubinNow Serum bilirubin concentration (milligrams per deciliter)Time frame: Baseline and 30 days
    • ChangedBefore UreaNow Serum urea concentration (milligrams per deciliter)Time frame: Baseline and 30 days
    • ChangedBefore CreatinineNow Serum creatinine concentration (milligrams per deciliter)Time frame: Baseline and 30 days
    Interventions Removed Chamomile tea and Green tea combined·Green tea (morning) and Chamomile tea (evening)
    + 1 other change: description
  2. Oct 30, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07907081
Lead sponsor
Iahtisham-Ul-Haq
Responsible party
Iahtisham-Ul-Haq (Principal Investigator, Imperial College of Business Studies, Pakistan) — Sponsor-investigator
First posted
Oct 30, 2026
Start date
Nov 12, 2018
Primary completion
Mar 15, 2019
Completion
Mar 15, 2019
Last update
Nov 4, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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