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Not yet recruitingNCT07730567Updated Jul 28, 2026

A Study to Evaluate the Pharmacokinetic Interaction and the Safety of AD-236A and AD-236B

A Phase 1 interventional study of Treatment A(AD-236A) and Treatment B(AD-236B) in Hyperlipidemia and Diabete Type 2, sponsored by Addpharma Inc.. Not yet recruiting at 1 site in South Korea. Open to participants aged 19 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-28.

Sponsored by Addpharma Inc. (part of Yuhan Corporation) · Phase 1, Interventional, and Treatment

Phase
Phase 1
Study type
Interventional
Enrollment
44
Allocation
Non-randomized
Ages
19 Years to 55 Years
Sex
All
01

Study summary

To evaluate the pharmacokinetic interaction and the safety of AD-236A and AD-236B in healthy adult volunteers

02

Conditions studied

  • Hyperlipidemia
  • Diabete Type 2
03

In context

Hyperlipidemias

861 studies on the registry are indexed under Hyperlipidemias; 110 are open to participants now.

This study's planned enrollment of 44 is below the median of 88 across 735 interventional studies indexed under Hyperlipidemias.

Browse Hyperlipidemias studies →

Lead sponsor

Addpharma Inc. is the lead sponsor of 58 studies on the registry; 25 are open to participants now.

First submitted after Addpharma Inc. became part of Yuhan Corporation.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
19 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Healthy adult volunteers aged ≥19 and ≤55 years at the time of the screening visit
  • Body weight ≥50 kg (≥45 kg for females) and (BMI) between 18.0 kg/m² and 30.0 kg/m² at the time of the screening visit

Exclusion criteria

Exclusion Criteria:

  • Participation in another clinical study with an drug within the 6 months from scheduled first administration
  • Other exclusions applied
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

Investigational drug or device

A drug or device being studied in a clinical trial.

It may be new, or already approved and being studied for another use, dose or form. Criteria often leave out people who took part in another study of one within a recent period, commonly 30 days or five half-lives.

05

Study design

Phase
Phase 1
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
44 participants (estimated)

Study arms

  • Experimental
    Arm A

    Period 1 : Treatment A(AD-236A), Period 2 : Treatment C(AD-236A+AD-236B)

    Drug: Treatment A(AD-236A) · Drug: Treatment C(AD-236A+AD-236B)

  • Experimental
    Arm B

    Period 1 : Treatment B(AD-236B), Period 2 : Treatment C(AD-236A+AD-236B)

    Drug: Treatment B(AD-236B) · Drug: Treatment C(AD-236A+AD-236B)

Interventions

  • DrugTreatment A(AD-236A)

    AD-236A Oral Tablet

  • DrugTreatment B(AD-236B)

    AD-236B Oral Tablet

  • DrugTreatment C(AD-236A+AD-236B)

    AD-236A+AD-236B Oral Tablet

06

What researchers measure

Primary outcomes

  1. 1. Area under the plasma concentration-time curve during dosing interval at steady state (AUCτ,ss)

    AUCτ,ss

    Time frame: pre-dose (0hour) to 24 hours post-dose

  2. Maximum concentration of drug in plasma at steady state (Cmax,ss)

    Cmax,ss

    Time frame: pre-dose (0hour) to 24 hours post-dose

07

Study locations

1 site
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 28, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07730567
Lead sponsor
Addpharma Inc.
Responsible party
Sponsor
First posted
Jul 28, 2026
Start date
Jul 29, 2026 (estimated)
Primary completion
Sep 13, 2026 (estimated)
Completion
Sep 26, 2026 (estimated)
Last update
Jul 28, 2026

Study contacts

Heeyoung Hong
Contact
hyhong@addpharma.co.kr
821094710619

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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