DrugSupplement
Berberine clinical trials
Includes 12 studies of Berberine hydrochloride.
- studies test it
- 67
- open now
- 11
- in phase 3
- 12
- first study started
- 2004
Keep track of what changes. Save the Berberine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Development codes
Studies by the year they started
67 studies that test it; most in 2016 (7)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2005 | 1 |
| 2008 | 1 |
| 2009 | 1 |
| 2010 | 1 |
| 2012 | 1 |
| 2013 | 1 |
| 2014 | 4 |
| 2015 | 5 |
| 2016 | 7 |
| 2017 | 3 |
| 2018 | 5 |
| 2019 | 5 |
| 2020 | 4 |
| 2021 | 7 |
| 2022 | 6 |
| 2023 | 4 |
| 2024 | 3 |
| 2025 | 3 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 3
- Phase 2
- 14
- Phase 3
- 12
- Phase 4
- 18
- No phase
- 28
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 65
Xijing Hospital of Digestive Diseases (11) · Tianjin Anding Hospital (6) · Xijing Hospital (3) · The University of Hong Kong (3) · Shanghai Jiao Tong University School of Medicine (3) · S.LAB (SOLOWAYS) (2) · University Medicine Greifswald (2) · National Polytechnic Institute, Mexico (2)
Often tested with
Tested in the same studies.
Vonoprazan (2) · Cinnamon (1) · Gymnema sylvestre (1) · Bezafibrate (1) · Bifidobacterium spp. (1) · Amoxicillin (1) · Pioglitazone (1) · Inulin (1)
Studies
Open first, then newest update. How each study uses Berberine is read from its arms, and is right about nine times in ten.
Testing it · 67
- Berberine in Treating Negative Symptoms of Schizophrenia: Clinical Efficacy and MechanismsEnrolling by invitationNot applicableTianjin Anding HospitalNCT07356765Written as Berberine
- Effects of Berberine on the Human Gut MicrobiomeNot yet recruitingNot applicableJing-yuan Fang, MD, Ph. DNCT07519681Written as Berberine Hydrochloride
- Evaluation of the Synergistic Effect of Combining a Prebiotic and a Postbiotic on Intestinal DiscomfortRecruitingNot applicableUniversité Catholique de LouvainNCT07420231Written as Berberine
- Effects of Berberine on Cardiometabolic OutcomesNot yet recruitingNot applicableUniversity of Central LancashireNCT07541898Written as Berberine
- Anti-platelet Effect of Berberine in Patients After Percutaneous Coronary InterventionRecruitingPhase 4Peking Union Medical College HospitalNCT03378934Written as Berberine
- Efficacy and Safety of Berberine for Gastric Intestinal MetaplasiaNot yet recruitingPhase 4Xijing Hospital of Digestive DiseasesNCT07129460Written as Berberine hydrochloride
- Comparative Efficacy of Metformin and Berberine Among TCF7L2 (rs7903146) TT vs. CC Genotype Carriers With Type 2 DiabetesNot yet recruitingNot applicableS.LAB (SOLOWAYS)NCT06911983Written as Berberine
- Study on the Sex-specific, Lipid- and Lipoprotein-lowering Effects of BerberineEnrolling by invitationPhase 2/3The University of Hong KongNCT06782646Written as Berberine
- Study on the Efficacy and Safety of Berberine, Minocycline, Esomeprazole, and Colloidal Bismuth Quadruple Therapy in the Initial Treatment of Helicobacter Pylori.RecruitingPhase 4Xijing Hospital of Digestive DiseasesNCT06603688Written as Berberine
- Effects Of Berberine Plus Inulin On Diabetes Care in Patients With LADANot yet recruitingPhase 4Second Xiangya Hospital of Central South UniversityNCT04698330Written as Berberine
- Cardiovascular Diseases and Diabetes Prevention Programme in Metabolic Syndrome (CDPP)Not yet recruitingPhase 4Tang YidaNCT05105321Written as Berberine
- Efficacy and Safety of Berberine in Non-alcoholic SteatohepatitisTerminatedPhase 2Fudan UniversityNCT03198572Written as Berberine
- Berberine Improving Cognitive Impairments in SchizophreniaCompletedNot applicableTianjin Anding HospitalNCT07359209Written as Berberine
- Berberine Supplementation, Sprint Interval Training, and Immune Function StudyCompletedNot applicableUniversity of Northern ColoradoNCT07480018Written as Berberine
- A Clinical Study to Evaluate the Effects of Akkermansia Muciniphila and Berberine on Prediabetes Among Obese Subjects.CompletedNot applicableYu ChenNCT05720299Written as Berberine
- Study on The Efficacy and Safety of Vonoprazan-containing Berberine Triple Therapy in Helicobacter Pylori First-Line EradicationCompletedPhase 4Xijing Hospital of Digestive DiseasesNCT06514274Written as Berberine
- Evaluating the Tolerability and Effects of Berberine on Major Metabolic Biomarkers: A Pilot StudyCompletedNot applicableUniversity of Kansas Medical CenterNCT03976336Written as Berberine
- A Pilot Study of Berberine (Soloways ™) in Patients with Type 2 Diabetes Mellitus Carrying TCF7L2 PolymorphismsCompletedNot applicableS.LAB (SOLOWAYS)NCT06863922Written as Berberine
- Impact of OCT1 and CYP2D6 Genotypes on Pharmacokinetics of Berberine in Healthy VolunteersCompletedNot applicableUniversity Medicine GreifswaldNCT05463003Written as Berberine
- Sex Differences in Berberine PharmacokineticsCompletedNot applicableUniversity Medicine GreifswaldNCT05845931Written as Berberine
See all 67 studies that test Berberine →
As the comparator · 2 — what is tested is compared with Berberine
- Effect of Gamma-cyclodextrin on the Bioavailability of BerberineNot yet recruitingPhase 1EuroPharma, Inc.NCT04918667Written as Berberine
- Polycystic Ovary Syndrome (PCOS): Effect Of Letrozole and BerberineStatus unknownNot applicableHeilongjiang University of Chinese MedicineNCT01116167Written as Berberine
Codes
What other systems call Berberine · ClinicalTrials.gg INT007064
- MeSH (NLM) D001599BerberineConfirmed NLM, Wikidata
- UNII (FDA) 0I8Y3P32UFBERBERINEConfirmed FDA, NLM, Wikidata
- RxNorm 1437Confirmed FDA, Wikidata
- Wikidata Q176525berberineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C83551BerberineConfirmed FDA, Wikidata
- DrugBank DB04115One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D001599 | Berberine | Confirmed NLM, Wikidata |
| UNII (FDA) | 0I8Y3P32UF | BERBERINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1437 | — | Confirmed FDA, Wikidata |
| Wikidata | Q176525 | berberine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C83551 | Berberine | Confirmed FDA, Wikidata |
| DrugBank | DB04115 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.