Hearing Loss, Sensorineural clinical trials
The registry lists 346 studies for Hearing Loss, Sensorineural across more than 10 countries. 100 are recruiting or about to start. 273 of them are mainly about Hearing Loss, Sensorineural (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 3 narrower conditions too, such as Presbycusis: 470 studies, 136 open.
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Who runs them
Cochlear (31) · Sonova AG (18) · MED-EL Elektromedizinische Geräte GesmbH (17) · Med-El Corporation (12) · Oticon Medical (11) · Advanced Bionics AG (9) · Northwestern University (7) · Frequency Therapeutics (6)
What is being tested here
Drugs under test in Hearing Loss, Sensorineural studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Acetylcysteine | 1 | 0 | 2 |
| Prednisone | 1 | 0 | 1 |
| Sodium thiosulfate | 1 | 0 | 1 |
| Mannitol | 1 | 0 | 1 |
| FX-322 | 0 | 0 | 5 |
| Valganciclovir | 0 | 2 | 3 |
| Ganciclovir | 0 | 2 | 3 |
| Brimapitide | 0 | 2 | 2 |
| NS101 | 0 | 0 | 1 |
| Donepezil | 0 | 0 | 1 |
Drug classes tested here Corticosteroids 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Multi-omics Characteristics and Prognosis of Idiopathic Sudden Sensorineural Hearing Loss · Dan Bing
- Nov 2026Improving Clinical Efficiency by Reducing Scheduled Follow-ups Using Cochlear America's Population Mean Mapping Strategy · Massachusetts Eye and Ear Infirmary
- Dec 2026Evaluation of Remote Programming of Cochlear Implants in Routine Cochlear Implant Follow-up · Advanced Bionics AG
- Dec 2026Anatomy-Based Fitting in Bimodal Cochlear Implant Users · Universitair Ziekenhuis Brussel
- Dec 2026Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting With or Without Synchronization · MED-EL Elektromedizinische Geräte GesmbH
- Dec 2026Single-Sided Deafness and Asymmetric Hearing Loss · Med-El Corporation
- Dec 2026Clinical Utility of Residual Hearing in the Cochlear Implant Ear · Ohio State University
- Dec 2026Cognitive Screening of Patients with Hearing Loss · University of Zurich
- Dec 2026Evaluation of the Efficacy and Safety of the Sullivan Cochlear Implant. · Todoc
- Dec 2026Protective Effect of Acetylcysteine Against Cisplatinum-Induced Ototoxicity: A Randomized Controlled Trial · Siriraj Hospital
Who these studies take
Of the 70 Hearing Loss, Sensorineural studies recruiting now, 39 (56%) set no upper age limit and 19 (27%) stop at 75 or younger. 26 (37%) take children under 18. 1 (1%) are for women only and 0 (0%) for men only; 17 (24%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 18 (26%) | 18 (26%) |
| 18 | 55 (79%) | 54 (77%) |
| 30 | 53 (76%) | 52 (74%) |
| 40 | 53 (76%) | 52 (74%) |
| 50 | 54 (77%) | 53 (76%) |
| 65 | 55 (79%) | 55 (79%) |
| 75 | 52 (74%) | 52 (74%) |
| 85 | 48 (69%) | 48 (69%) |
Across all 346 studies, recruiting or not: 27% stop at 75 or younger and 19% at 65; 25% take children; 1% are for women only and <1% for men only; 27% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hearing Loss, Sensorineural studies take
Of 162 interventional studies with no phase under Hearing Loss, Sensorineural, half reached primary completion within 22 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 22 mo6–44 · 162 studies | 14 mo2–23 · 80 studies | 32 mo18–49 · 82 studies |
| Observational | 49 mo13–… · 42 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
- Retrospectively Investigating Longitudinal Outcomes in MED-EL SONATA 2 Cochlear Implant Recipients.Nov 5, 2026NCT07697911
- Cisplatin-induced Cochlear and Vestibular Damage in Head and Neck CancerOct 20, 2026NCT06929468
Stopped1
- Cross-sectional and Prospective Study to Characterize Early-onset PresbycusisTerminatedOct 26, 2026NCT06354010
Newly registered3
- Post-Market Registry Study for Vibrant Hearing SolutionsOct 30, 2026NCT07906314
- Effect of a Totally Implantable Cochlear Implant on Tinnitus Severity in Adults With Preoperative TinnitusOct 26, 2026NCT07893860
- Comparing an AI-driven Hearing Test With the Standard Hearing Test in Adults With Hearing Loss and TinnitusOct 26, 2026NCT07895004
Studies
Recruiting first, then most recently updated. Showing 50 of 346. Browse all 346 → or search them.
- Effect of a Totally Implantable Cochlear Implant on Tinnitus Severity in Adults With Preoperative TinnitusNot yet recruitingNCT07893860Not applicable1 country
- Retrospective Analysis of Speech Performance Using the HiRes Ultra and HiRes Ultra 3D Cochlear ImplantRecruitingNCT063015811 country
- Retrospectively Investigating Longitudinal Outcomes in MED-EL SONATA 2 Cochlear Implant Recipients.RecruitingNCT076979111 country
- Post-Market Registry Study for Vibrant Hearing SolutionsEnrolling by invitationNCT079063141 country
- Long Term Follow-up Study of AAVAnc80-hOTOF Gene TherapyEnrolling by invitationNCT066964563 countries
- Barriers and Facilitators to OTC Hearing Aids SuccessRecruitingNCT06499805Not applicable1 country
- Comparing an AI-driven Hearing Test With the Standard Hearing Test in Adults With Hearing Loss and TinnitusEnrolling by invitationNCT078950041 country
- Cisplatin-induced Cochlear and Vestibular Damage in Head and Neck CancerRecruitingNCT069294681 country
- Alpha-Tectorin, Interleukin-10 and Thiol-Disulfide Homeostasis in Children With Congenital Hearing LossRecruitingNCT078605801 country
- First In Human Randomised Trial of Rincell-1 in Adults With a Cochlear ImplantNot yet recruitingNCT07032038Phase 1/21 country
- Gene Therapy Trial for Otoferlin Gene-mediated Hearing LossRecruitingNCT05821959Phase 34 countries
- Genetic and Epigenetic Background of Inner Ear Dysfunction in Turner SyndromeRecruitingNCT065070071 country
- Vestibular and Postural Function in an Unselected Group of Children With Sensorineural Hearing LossRecruitingNCT062297171 country
- Open-label Study of SKY-GJB2 in Pediatric Subjects With GJB2-mediated Hearing LossRecruitingNCT07627971Phase 1/21 country
- Auditory Intranerve Stimulation Perceptual StudyRecruitingNCT07789665Not applicable1 country
- Listening Effort in Cochlear Implant UsersRecruitingNCT06516575Not applicable1 country
- Assessing the Effect of Computer-based Auditory Training on Adult Cochlear Implant Speech and Quality-of-life OutcomesRecruitingNCT06607146Not applicable1 country
- A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin MutationsRecruitingNCT05788536Phase 1/25 countries
- Clinical Evaluation of Hearing Aid OTC Self-Assessment Methods for Adults With Perceived Mild-to-Moderate Hearing LossNot yet recruitingNCT07738237Not applicable1 country
- Middle Ear Optical Coherence Tomography Imaging and Vibrometry in Patients With Hearing LossNot yet recruitingNCT077329201 country
- The Effect of Anatomy-based Fitting on the Perception of Speech in Noise and Music in Single-sided Deaf Cochlear Implant UsersRecruitingNCT07703800Not applicable1 country
- Intracochlear Platelet-rich Fibrin Application in Cochlear ImplantationRecruitingNCT05215197Not applicable1 country
- Anatomy-Based Fitting in Bimodal Cochlear Implant UsersRecruitingNCT07691853Not applicable1 country
- Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode ArrayRecruitingNCT069364491 country
- Perceptual Adaptation Following Cochlear Implantation (Aim 3a)RecruitingNCT07039435Not applicable1 country
- Anatomy-Based Fitting in Unexperienced Cochlear Implant UsersRecruitingNCT05451628Not applicable1 country
- Microtable® Method for Cochlear Implantation Investigational Device Exemption (IDE)Not yet recruitingNCT03101917Not applicable1 country
- Protein Biomarkers and Host RNA Expression Profiles in Congenital Cytomegalovirus InfectionRecruitingNCT076353681 country
- Maximizing Quality of Life After Cancer Through RehabilitationNot yet recruitingNCT07622407Not applicable1 country
- Natural History in Children up to 16 Years With Mild to Profound Hearing Loss Due to Mutations in GJB2 / OTOF GenesRecruitingNCT054028131 country
- Clinical Evaluation of the RH210 Hearing AidRecruitingNCT07572357Not applicable1 country
- Evaluation of Remote Programming of Cochlear Implants in Routine Cochlear Implant Follow-upRecruitingNCT068943031 country
- Improving Clinical Efficiency by Reducing Scheduled Follow-ups Using Cochlear America's Population Mean Mapping StrategyRecruitingNCT06960616Not applicable1 country
- Speech Perception of a Tonotopy-based Fitting for Cochlear Implant Recipients for 6 Months With Conventional SettingRecruitingNCT06723262Not applicable1 country
- Comparison of Speech Understanding Between Tonotopy-based Fitting and Setting Based on Evolutionary AlgorithmsRecruitingNCT06737185Not applicable1 country
- A Randomized Trial of Intratympanic Drug Delivery: Evaluating the Efficacy and Safety of Dexamethasone-Loaded Exosomes Versus Standard Therapy in Acute Sensorineural Hearing Loss.RecruitingNCT07568184Not applicable1 country
- Understanding Individual Listening StrategiesEnrolling by invitationNCT06962540Not applicable1 country
- Characterizing Variability in Hearing Aid Outcomes in Among Older Adults With Alzheimer's DementiaRecruitingNCT04240561Not applicable1 country
- A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered SoundRecruitingNCT07304024Phase 1/21 country
- Effects of Binaural Hearing on Listening Effort and Cognitive Development in Mandarin-speaking Children With Cochlear ImplantsRecruitingNCT075097881 country
- BEARS Training Package to Maximise Hearing Abilities in Older Children and Teenagers With Bilateral Cochlear ImplantsRecruitingNCT05808543Not applicable1 country
- Yiyuancong for the Treatment of Sudden Sensorineural Hearing LossRecruitingNCT07505667Not applicable1 country
- Impact of Anatomy-Based Cochlear Implant Programming on Early PerformanceEnrolling by invitationNCT06734039Not applicable1 country
- Regenerative Medicine and Stem Cell-Based Interventions for Inner Ear Trauma, Tinnitus, and Sensorineural Hearing LossEnrolling by invitationNCT07472023Early Phase 11 country
- Optimizing Cochlear Implant Laterality in Patients With Unilateral Vestibular WeaknessNot yet recruitingNCT07452653Not applicable
- Otoferlin Gene-mediated Hearing Loss Natural History StudyRecruitingNCT055720737 countries
- Cochlear Implant Recipients: Comprehensive Longitudinal EvaluationRecruitingNCT073802691 country
- Preschool Hearing ScreeningRecruitingNCT06058767Not applicable1 country
- Correlations Between Subjective and Objective Responses to Cochlear Implant StimulationNot yet recruitingNCT07371299
- Protective Effect of Acetylcysteine Against Cisplatinum-Induced Ototoxicity: A Randomized Controlled TrialRecruitingNCT07364747Phase 21 country