Hearing Loss, Noise-Induced clinical trials
The registry lists 46 studies for Hearing Loss, Noise-Induced across more than 10 countries. 10 are recruiting or about to start. 37 of them are mainly about Hearing Loss, Noise-Induced (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Who runs them
Frequency Therapeutics (4) · Washington University School of Medicine (3) · Direction Centrale du Service de Santé des Armées (2) · Medical Corps, Israel Defense Force (2) · University of California, San Francisco (2) · University of Michigan (2) · Chang Gung Memorial Hospital (1) · University Hospital Sestre Milosrdnice (1)
What is being tested here
Drugs under test in Hearing Loss, Noise-Induced studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| FX-322 | 0 | 0 | 4 |
| Zonisamide | 0 | 0 | 3 |
| Hyaluronic Acid | 0 | 0 | 1 |
| Alpha-tocotrienol quinone | 0 | 0 | 1 |
| Gluconic acid | 0 | 0 | 1 |
| Brimapitide | 0 | 0 | 1 |
| Gabapentin | 0 | 0 | 1 |
| Ebselen | 0 | 0 | 1 |
| Methylprednisolone | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Feb 2027OCCUPATIONAL NOISE AND CHEMICAL EXPOSURE EFFECTS ON AUDITORY AND VESTIBULAR FUNCTION · Ondokuz Mayıs University
- Mar 2027Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss · Restorear Devices LLC
- Aug 2027Prevention of Noise-Induced Hearing Loss in Primary Education · Erasmus Medical Center
Who these studies take
Of the 5 Hearing Loss, Noise-Induced studies recruiting now, 1 (20%) set no upper age limit and 4 (80%) stop at 75 or younger. 2 (40%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (60%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (20%) | 1 (20%) |
| 18 | 3 (60%) | 3 (60%) |
| 30 | 3 (60%) | 3 (60%) |
| 40 | 3 (60%) | 3 (60%) |
| 50 | 4 (80%) | 4 (80%) |
| 65 | 3 (60%) | 3 (60%) |
| 75 | 1 (20%) | 1 (20%) |
| 85 | 1 (20%) | 1 (20%) |
Across all 46 studies, recruiting or not: 61% stop at 75 or younger and 59% at 65; 15% take children; 0% are for women only and 2% for men only; 72% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
- A Multilevel Intervention to Prevent Noise Exposure in FarmworkersNov 9, 2026NCT07554378
Stopped1
- Apple Hearing StudyTerminatedNov 2, 2026NCT04172766
Studies
Recruiting first, then most recently updated. Showing 46 of 46. search them.
- A Multilevel Intervention to Prevent Noise Exposure in FarmworkersEnrolling by invitationNCT07554378Not applicable1 country
- OCCUPATIONAL NOISE AND CHEMICAL EXPOSURE EFFECTS ON AUDITORY AND VESTIBULAR FUNCTIONNot yet recruitingNCT078061231 country
- Intervention for Hearing Health Among Native AmericansNot yet recruitingNCT07534098Not applicable1 country
- Comparative Efficacy of Earplug Usage InstructionEnrolling by invitationNCT07731321Not applicable1 country
- Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing LossRecruitingNCT06729632Not applicable1 country
- A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered SoundRecruitingNCT07304024Phase 1/21 country
- Prevention of Noise-Induced Hearing Loss in Primary EducationRecruitingNCT07513077Not applicable1 country
- Regenerative Medicine and Stem Cell-Based Interventions for Inner Ear Trauma, Tinnitus, and Sensorineural Hearing LossEnrolling by invitationNCT07472023Early Phase 11 country
- Preschool Hearing ScreeningRecruitingNCT06058767Not applicable1 country
- Three-dimensional Perception of Sounds in Military with Acoustic TraumaRecruitingNCT054685671 country
- Apple Hearing StudyTerminatedNCT041727661 country
- The Growing Burden of Hearing-Related Disability.CompletedNCT077986871 country
- A Phase 2b Study of SPI-1005 to Prevent Acute Noise Induced Hearing LossWithdrawnNCT02779192Phase 21 country
- Noise-Induced Hearing Loss-Acute Exposure Treatment (UA)TerminatedNCT04774250Phase 21 country
- Hearing/ET/Vestibular in Balloon PilotsCompletedNCT072003101 country
- Understanding the Consequences of Recreational Noise ExposureCompletedNCT050763441 country
- Noise-Induced Hearing Loss-Acute Exposure TreatmentTerminatedNCT04768569Phase 21 country
- Does Sound Conditioning Protect Against Temporary Hearing DamageCompletedNCT038788751 country
- Verification of the Efficacy/safety of the Intratympanic Drug Delivery for Hearing LossCompletedNCT04766853Phase 1/21 country
- FX-322 in Adults With Stable Sensorineural Hearing LossCompletedNCT04120116Phase 21 country
- FX-322 in Adults With Acquired Sensorineural Hearing LossCompletedNCT05086276Phase 21 country
- Determination of the Effects of Noise Level in the Operating RoomStatus unknownNCT05636488
- Study of Diagnostic Biomarkers of Acute Acoustic TraumaStatus unknownNCT048322301 country
- Study of the Use of Hearing Protection Equipment in the Occurence of Acute Acoustic Trauma in the ArmyCompletedNCT048049821 country
- The Effect of Acupuncture on Patients With Noise-induced Hearing LossStatus unknownNCT05511753Not applicable
- Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL)TerminatedNCT02903355Phase 31 country
- FX-322 in Adults With Age-Related Sensorineural Hearing LossCompletedNCT04601909Phase 11 country
- Noise Exposure and Near-Infrared LightCompletedNCT03834714Not applicable1 country
- FX-322 in Adults With Severe Sensorineural Hearing LossCompletedNCT04629664Phase 11 country
- Protective Effects of EPI-743 on Noise-Induced Hearing LossCompletedNCT02257983Phase 21 country
- Efficacy of Various Treatments for Acute Acoustic Trauma.Status unknownNCT044829981 country
- ABR Characteristics and Salivary Cortisone Concentration in Noise-exposed WorkersStatus unknownNCT041833611 country
- Prevention of Noise-induced Hearing LossWithdrawnNCT02049073Phase 1/21 country
- Risk Factors for Hearing Loss as a Result of Exposure to Noise During Military Training in the IDFStatus unknownNCT03314116Not applicable1 country
- Micronutrients to Prevent Noise-induced Hearing LossCompletedNCT00808470Phase 21 country
- Test of Hearing Health Education Programs for Farm and Rural YouthCompletedNCT02472821Not applicable1 country
- Improvement of Tinnitus After Oral Zinc on Patients With Noise-induced Hearing LossCompletedNCT02951715Not applicable
- TUNE! Teaching the UK About Noise Exposure: A Pilot StudyCompletedNCT00916305Not applicable1 country
- Test of a Web-based Intervention to Promote Hearing Protector UseCompletedNCT01454895Not applicable1 country
- Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus NACCompletedNCT02259595Phase 11 country
- Hearing Loss Prevention for VeteransCompletedNCT01038336Not applicable1 country
- Efficacy of AM-111 in Patients With Acute Sensorineural Hearing LossCompletedNCT00802425Phase 21 country
- Prevention of Noise-induced Damage by Use of AntioxidantsStatus unknownNCT01727492Not applicable1 country
- Incidence of Tinnitus Amongst Teenagers and Young Adults mp3 UsersCompletedNCT011872511 country
- Study of Attention Deficit/Hyperactivity Disorder Using Transcranial Magnetic StimulationCompletedNCT000019151 country
- The Effect of Gabapentin on the Sensation and Impact of TinnitusCompletedNCT00257270Phase 2