Presbycusis clinical trials
The registry lists 66 studies for Presbycusis across more than 10 countries. 21 are recruiting or about to start. 49 of them are mainly about Presbycusis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Status
Who runs them
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (5) · Yu-Hsiang Wu (4) · The Hong Kong Polytechnic University (3) · University Hospital, Angers (2) · Johns Hopkins University (2) · US Department of Veterans Affairs (2) · Chinese PLA General Hospital (2) · University Hospital, Toulouse (2)
What is being tested here
Drugs under test in Presbycusis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Dec 2026A Clinical Trial of the Safety and Efficacy of TJ0113 Capsules in the Treatment of Patients With Age-related Hearing Loss · Yilai Shu
- May 2027Hidden Hearing Loss in Older Adults · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
- Jul 2027Hearing Healthcare Assessment in Rural Communities · Matthew Bush, MD
- Aug 2027Optimizing Elderly Hearing Loss Care in Hong Kong A Cost-Effectiveness and Satisfactory Analysis of a Pilot Collaborative Model Between Otorhinolaryngologists and Family Medicine Specialists · Tseung Kwan O Hospital, Hong Kong
- Oct 2027First Clinical Study to Evaluate Safety, Tolerability & PK of DX243 in Healthy Volunteers and Patients With Hearing Loss · Dendrogenix
Who these studies take
Of the 9 Presbycusis studies recruiting now, 4 (44%) set no upper age limit and 2 (22%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 3 (33%) | 3 (33%) |
| 30 | 3 (33%) | 3 (33%) |
| 40 | 3 (33%) | 3 (33%) |
| 50 | 4 (44%) | 4 (44%) |
| 65 | 9 (100%) | 9 (100%) |
| 75 | 8 (89%) | 8 (89%) |
| 85 | 7 (78%) | 7 (78%) |
Across all 66 studies, recruiting or not: 12% stop at 75 or younger and 5% at 65; 2% take children; 2% are for women only and 0% for men only; 45% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Presbycusis studies take
Of 25 interventional studies with no phase under Presbycusis, half reached primary completion within 29 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 29 mo11–58 · 25 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Stopped1
- Cross-sectional and Prospective Study to Characterize Early-onset PresbycusisTerminatedOct 26, 2026NCT06354010
Studies
Recruiting first, then most recently updated. Showing 50 of 66. Browse all 66 → or search them.
- HEARS Maryland: Extending Capacity for Affordable, Accessible Hearing Care Through Older Adult Peer MentorshipNot yet recruitingNCT07699146Not applicable
- Barriers and Facilitators to OTC Hearing Aids SuccessRecruitingNCT06499805Not applicable1 country
- First In Human Randomised Trial of Rincell-1 in Adults With a Cochlear ImplantNot yet recruitingNCT07032038Phase 1/21 country
- Optimizing Elderly Hearing Loss Care in Hong Kong A Cost-Effectiveness and Satisfactory Analysis of a Pilot Collaborative Model Between Otorhinolaryngologists and Family Medicine SpecialistsNot yet recruitingNCT077821771 country
- Impact of Auditory Stimulation in Eating Pleasure (EDERE 2021)RecruitingNCT049230871 country
- Hidden Hearing Loss in Older AdultsRecruitingNCT076461191 country
- First Clinical Study to Evaluate Safety, Tolerability & PK of DX243 in Healthy Volunteers and Patients With Hearing LossRecruitingNCT07637981Phase 21 country
- Prediction of Age-Related Hearing Loss Based on Comprehensive Risk FactorsNot yet recruitingNCT07612618
- Management of Age-Related Auditory Decline and Early Warning of Its Co-occurring DementiaNot yet recruitingNCT076086401 country
- A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered SoundRecruitingNCT07304024Phase 1/21 country
- Benefits of Choir for Older Adults With Unaddressed Hearing Loss (WP2)RecruitingNCT06580847Not applicable5 countries
- Comparing the Efficacy of Domestic Versus Imported Hearing Aids in ARHLRecruitingNCT06882889Not applicable1 country
- Hearing-physical Activity InterventionNot yet recruitingNCT07071168Not applicable
- A Clinical Trial of the Safety and Efficacy of TJ0113 Capsules in the Treatment of Patients With Age-related Hearing LossNot yet recruitingNCT07012746Not applicable1 country
- Hearing Screening in Adults Over 50 Years OldEnrolling by invitationNCT06894927Not applicable1 country
- Increasing Physical Activity with a Social Robot-assisted Exercise Intervention in Older Adults with Hearing Loss: a Feasibility and Pilot Randomized Controlled TrialNot yet recruitingNCT06878339Not applicable
- Development of a Battery of Audiological Tests for the Precision Diagnosis of Age-related Hearing LossRecruitingNCT05312983Not applicable1 country
- Effects of Huperzine a on Presbycusis(Δ,kHz, DB,MMSE, AD)Enrolling by invitationNCT03101722Not applicable1 country
- Evaluation of a Digital Therapy of Auditory TrainingNot yet recruitingNCT05848661Not applicable
- Hearing and Cognition in Aging AdultsNot yet recruitingNCT061834501 country
- A Prospective Cohort Study On Change of Cognitive Function In Aged-related Hearing Loss With Hearing AidsRecruitingNCT05694039Not applicable1 country
- Cross-sectional and Prospective Study to Characterize Early-onset PresbycusisTerminatedNCT063540102 countries
- Improving Speech in Noise Perception for Individuals With Age-related Hearing LossCompletedNCT07192757Not applicable1 country
- Communication Training in Hearing Aid UsersCompletedNCT07798453Not applicable1 country
- Hearing Healthcare Assessment in Rural CommunitiesActive, not recruitingNCT05786794Not applicable1 country
- Evaluation of the Impact of Cochlear Implants on Cognition in Older AdultsCompletedNCT02729402Not applicable
- Sight and Hearing Investigation Into Effects on DeliriumCompletedNCT061766251 country
- Age-related Hearing Loss and Lexical DisordersCompletedNCT036383231 country
- Efficacy and Safety of Liuwei Dihuang Pill Versus Placebo in Presbycusis With Shen (Kidney)-Yin DeficiencyCompletedNCT05125081Phase 21 country
- Clinical Trial on Alzheimer Disease, Presbycusis and Hearing AidsCompletedNCT00488007Not applicable1 country
- Postural Modification and Hearing Aids in PresbycusisCompletedNCT05706051Not applicable1 country
- Auditory-Cognitive Dual-Task Intervention for Older Adults With Hearing LossCompletedNCT06486285Not applicable1 country
- Audiovestibular Function in Infratentorial Superficial SiderosisCompletedNCT042006641 country
- Hearing Aid and Individuals With Cognitive DisordersCompletedNCT04049643Not applicable1 country
- Cognitive Function and EEG Brain Network Remodeling Among Users of Hearing Aids With ARHLActive, not recruitingNCT068934321 country
- Cognitive Training to Improve Mobility in Middle-aged and Older AdultsCompletedNCT05418998Not applicable1 country
- Early Identification of Age-related Hearing ImpairmentCompletedNCT064183211 country
- Hearing for Communication and Resident EngagementCompletedNCT04575051Not applicable1 country
- Effects of PSAPs on Speech ProcessingCompletedNCT05076045Not applicable1 country
- Impact of Hearing Aid Service-delivery Model and Technology on Patient OutcomesCompletedNCT03579563Not applicable1 country
- Longitudinal Outcomes of Hearing AidsCompletedNCT04030299Not applicable1 country
- Hearing Aids Use in Elderly: Efficacy in Speech Perception and in Health-related Quality of LifeCompletedNCT043330431 country
- Task Training In Older Adults With Age-Related Hearing LossCompletedNCT05190081Not applicable1 country
- Study of Cognitive Reserve Disorder Affecting Depression in Aged Related Hearing Loss Via Rest State EEGStatus unknownNCT058927311 country
- PET-CT-based Study of Central Mechanisms of Cortical Metabolism in 18F-FDG and 18F-AV1451 Age-related DeafnessStatus unknownNCT057960111 country
- Evaluation of Hearing Aids Rehabilitation Within Age-related Hearing Loss Population.Status unknownNCT05331404Not applicable1 country
- FX-322 in Adults With Age-Related Sensorineural Hearing LossCompletedNCT04601909Phase 11 country
- Objective Measurement of Hearing Aid BenefitWithdrawnNCT04431622Not applicable
- Hearing Loss and Communication Needs in a Group Care Setting for Older AdultsStatus unknownNCT04659967Not applicable1 country
- Study of the Association Between Presbycusis With the Incidence of FrailtyStatus unknownNCT043601091 country